• 제목/요약/키워드: Medicinal Material

검색결과 493건 처리시간 0.029초

Phytobiotic소재 선발을 위한 약용식물 추출물의 항산화 및 항균 활성 (Antioxidative and Antimicrobial Activities of Medicinal Plant Extracts for Screening Phytobiotic Material)

  • 정희경;김영진;박병권;박승춘;정유석;홍주헌
    • 한국식품영양과학회지
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    • 제36권10호
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    • pp.1235-1240
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    • 2007
  • Phytobiotic으로 활용 가능한 소재를 선발하기 위하여 9종의 약용식물인 진피, 매자나무 뿌리, 매자나무 줄기, 상백피, 석곡, 석창포, 취나물, 택사, 호장근의 열수 추출물을 대상으로 항산화성 및 항균활성을 조사하였다. 호장근은 총폴리페놀 함량이 $725.8{\mu}g/mL$로 가장 높았으며, 전자공여능이 85.9%, 아질산염 소거능이 92.7%로 우수한 항산화성을 나타내었다. 또한 호장근은 0.8 mg/mL의 농도에서 P. aeruginosa, E. coli, B. cereus, S. Typhimurium, L. monocytogenes, K. pneumoniae, S. aureus의 생육을 저해하였다. 호장근 추출물은 7종의 균주에 대해 항균활성을 나타내었고, 특히 K. pneumoniae, S. aureus에 대해서 지속적인 항균활성을 나타내었다. K. pneumoniae, S. aureus에 대한 $IC_{50}$은 각각 6.24 mg/mL, 1.8 mg/mL이었다. 호장근은 항산화성 및 항균활성을 동시에 가지는 기능성 약용식물 추출물로 가축의 phytobiotic소재로 활용 가능함을 확인하였다.

감초 육성품종 뿌리 추출물의 In vitro 활성 평가 (Evaluation of the In vitro Activity of Glycyrrhiza Cultivar Roots)

  • 이승은;이정훈;박춘근;김형돈;이윤지;서경혜;정현수;장재기;김동휘
    • 한국약용작물학회지
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    • 제27권2호
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    • pp.115-125
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    • 2019
  • Background: Glycyrrhiza radix (licorice root) have been used as an oriental medicine material for long time, and its protective effects on oxidative stress, inflammation and cognition deficit have been recently reported. However, the cultivation of Glycyrrhiza species as medicinal crops is associated with some problems such as low productivity and early leaf fall, etc. To resolve this problems, Glycyrrhiza cultivars have been developed by direct hybridization of each Glycyrrhiza species by Korean researchers. The present study was conducted to compare the Glycyrrhiza cultivar radix (Dagam, Sinwongam and Wongam) for their anti-oxidation, anti-inflammation, and cognition improvement effects and levels of liquiritin, isoliquiritigenin and licochalcone in order to select an excellent cultivar as a material resource. Methods and Results: For evaluating the inhibitory efficacies of the Glycyrrhiza cultivar extracts on oxidative stress and inflammation in BV2 cells, we measured their reactive oxygen species (ROS) production and nitric oxide (NO) release after treating them with lipopolysccharide. The scavenging activities on 2,2-diphenyl-1-picrylhydrazyl (DPPH) and peroxynitrite ($NOO^-$) radicals were evaluated. Cell proliferation and N-methyl-D-aspartate receptor (NMDAR) inhibition were analyzed. The total phenol, liquiritin, isoliquiritigenin and licochalcone A content in the extracts of the three culivars were quantified. Furthermore, the correlation coefficient between the activities and contents of total phenol, liquiritin, isoliquiritigenin and licochalcone A were also calculated. The results indicated that Sinwongam exhibited potent anti-oxidant, anti-inflammatory and NMDAR inhibititory activities. Sinwongam also showed higher total phenol and licochalcone A contents than the other cultivars. Among the three cultivars, Dagam exhibited a positive effects on NO release inhibition, cell proliferation and contents of liquiritin and isoliquiritigenin. Conclusions: Sinwongam is expected to be the most useful resource as a functional material for anti-oxidation/anti-inflammation and cognition improvement among the three studied licorice cultivars.

생약재 추출물로부터 주름 개선 소재의 발굴 및 이를 이용한 화장품의 안정성 시험 (Screening of Anti-wrinkle Resource from Herbal Medicinal Extracts and Stability Test of Its Cosmetic Products)

  • 조은아;조은혜;최선주;박근형;김소영;정윤주;구창섭;하병집;장동일;채희정
    • 한국약용작물학회지
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    • 제19권2호
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    • pp.126-135
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    • 2011
  • Various herbal medicinal extracts were examined for the development of cosmetic products with anti-oxidative and anti-wrinkle activity. First, total polyphenol contents and DPPH radical scavenging activities of herbal medicinal extracts were measured. Most herbal samples, except for DW extracts of Portulaca oleracea, Caesalpinia sappan, Taraxacum platycarpum, Carthamus tinctorius, and 70% EtOH extracts of Taraxacum platycarpum and Carthamus tinctorius, showed DPPH radical scavenging activity over 80% at a concentration of $400{\mu}g/m{\ell}$. SOD-like antioxidant activity of DW extracts of Syzygium aromaticum, DW extracts of Eriobtrya japonica and 70% EtOH extracts of Sophora japonica was measured as 40%, 35% and 80%, respectively at a dry matter concentration of $50{\mu}g/m{\ell}$. In elastase inhibition assay, DW extracts of Lycium chinense ($50{\mu}g/m{\ell}$) and 70% EtOH extracts of Areca catechu ($50{\mu}g/m{\ell}$) showed 50% and 40% of inhibition, respectively. At a concentration of $1.250{\mu}g/m{\ell}$, DW extracts of Lycium chinense and 70% EtOH extracts of Areca catechu showed 10% and 30% of collagenase inhibition, respectively. Skin and lotion samples were prepared using the two herbal extracts of high anti-wrinkle activity: Lycium chinense extract and Areca catechu extract. The storage stability of skin and lotion containing each of the selected herbal extracts was evaluated. pH and viscosity were used as stability indicators for the stability test under different storage temperatures and freeze-thaw cycle conditions. The skin and lotion containing each of DW extract of Lycium chinense and 70% EtOH extract of Areca catechu was showed high pH and viscosity stability. The skin and lotion containing DW extracts of Lycium chinense showed relatively higher stability than the skin and lotion containing 70% EtOH extract of Areca catechu, at cycle chamber and freeze-thaw conditions. In summary, these results indicated that cosmetics containing DW extract of Lycium chinense were relatively stable, and this herbal extract could be used as a stable functional cosmetic material.

작약(芍藥) 분주묘(分株苗) 크기에 따른 생육(生育)과 품질(品質) (Effects of Divided Crown Size on the Growth and Quality of Paeonia lactiflora Pallas)

  • 김세종;박준홍;김기재;박소득;최부술
    • 한국약용작물학회지
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    • 제6권3호
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    • pp.198-203
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    • 1998
  • 작약 분주묘의 크기에 따른 생육과 품질을 조사하여 재배법 개선의 기초자료로 활용코자 1994년 10월부터 3개년간 의성에서 의성작약을 공시하여 수행한 시험 연구 결과는 다음과 같다. 1. 작약의 분주묘 크기가 클수록 출현을 및 활착율은 높은 경향이 었으며 지상부 생육도 양호하었다. 2. 소묘$(30{\sim}50g)$재배의 지하부 수량은 1,921kg/10a이었으나 중묘$(60{\sim}80g)$는 2,304kg, 대 묘$(60{\sim}80g)$는 2,674kg으로서 각각 30%, 39% 증수되어 재식종묘 크기가 클수록 증수 되었다. 3. 분주묘 크기별 뿌리 굵기 10mm이상의 상품량은 소묘재배가 1,406kg/10a인데 비하여 중묘는 1,554kg/10a, 대묘는 1,769kg/10a으로 중묘와 대묘 재배시 상품율은 각각 11%, 26%높았다. 4. 분주묘 크기별 소득은 소묘가 1,133천원/10a인 데 비하여 중묘나 대묘는 각각 28%, 48% 증가 되었고 노두 생산량도 분주묘가 클수록 증수되었다.

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Effect of Soluble-silicate or Chitosan Foliar Spray on Ginseng Cultivated in Blue-white Plastic Film House

  • Seo, Sang Young;Cho, Jong hyeon;Kim, Chang Su;Kim, Hyo Jin;Kim, Dong Won;An, Min Sil;Jang, In Bae
    • 한국자원식물학회:학술대회논문집
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    • 한국자원식물학회 2019년도 추계학술대회
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    • pp.46-46
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    • 2019
  • The experiments were performed in the Jinan (elevation: 300 meters above sea level), Jeollabuk-do. Seedlings (n = 63 per $3.3m^2$) of ginseng cultivar (Cheonpung, Yeonpung) were planted on April 10, 2015. Shading material of plastic film house was blue-white film. Before the Planting seedling, silicate (3 kg/10 a) or chitosan (40 kg/10 a) was fertilized and foliar sprayed on the leaves 1000 times dilution solution once a month from May to September every year. The growth results of 5-year old ginseng surveyed in 2018 are as follows. The average air temperature in the plastic film house was the highest at $26.6^{\circ}C$ and $26.5^{\circ}C$ in July and August, respectively, and the highest temperature was $40.5^{\circ}C$ in July. The maximum daily temperature of $35^{\circ}C$ or more was 30 days, with the average soil temperature being $24.9^{\circ}C$ in August. The chemical properties of the test soil are as follows. pH was 6.4~6.9 level and EC was 0.35~0.46 dS/m. The organic matter content was 33.5~41.4 g/kg, and available-P content was 251.9~306.8 mg/kg. Exchangeable cations contents, such as K, Ca and Mg were all the appropriate ranges. The soil microbial density surveyed by the dilution plate method was 10~50 times higher than that of control (Non-treatment) and actinomycete density was 3~6 times higher. Pathogens of the genus Fusarium by Metagenome analysis decreased 91.3% and 68.2% respectively in the foliar sprayed of chitosan and soluble-silicate. The light intensity (PAR) in the blue-white film plastic film house gradually increased until July and then decereased, with the average of light intensity in March-October was $120.3umol/m^2/s$. The growth of aerial parts such as plant height and stem length was better than non-sprayed group in silicate or chitosan treatments and Yeonpung cultivar was superior to the Cheonpung cultivar. The SPAD value was higher in Yeonpung cultivar foliar sprayed with soluble-silicate. The growth of underground parts such as root length and taproot length were better in chitosan and soluble-silicate treatment than control, especially in Yeonpung cultivar foliar sprayed with chitosan was good in taproot length and taproot diameter, and fresh weight of root was 60.1 g. Ginsenoside contents were 24.9 mg/g and 22.4 mg/g, in the Cheonpung cultivar foliar sprayed with soluble-silicate or chitosan respectively, 28% and 15% higher than control (19.5 mg/g). The incidence of disease by Alteraria panax and Botrytis cinerea was 3~9% and 4~9%, respectively. High temperature damage rate was 3~5%.

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전통식물이 건강에 미치는 영향 (The Effect of a Traditional Food on Health)

  • 신민교
    • 동아시아식생활학회지
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    • 제6권2호
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    • pp.273-276
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    • 1996
  • The Traditional Food mean the plants which bear nutritional function and of which purpose is keeping health. However, when it is used for protection or cure of disease, we can call them medicinal substances. Therefore medicine and eating are ultimately same. Because of this point of a dietetic material medical foodstuff, if we obey Mother Nature and make a balanced diet, everyone will be able to enjoy a long life with keeping health.

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Immobilization of Alchidine on Polyvinyl Alcohol Gels

  • Soh, Dea-wha
    • Transactions on Electrical and Electronic Materials
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    • 제4권1호
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    • pp.11-14
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    • 2003
  • The regularities of immobilization of natural medicinal substances - alchidine on gels of poly(vinyl alcohol) - are investigated. It is shown that the polymer components of alchidine interact with nonionic polymer with formation of interpolymer complexes. The influence of the different factors on the properties of complexes is considered and the constants of alchidine distribution in the system gel - water are calculated.