• 한국식생활문화학회지
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• 제13권5호
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• pp.431-460
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• 1998

After the Japanese Invasion of Korea in 1592, correspondents of Chosun called on Japan twelve times, as a mission, from 1607 to 1811. The suite of Chosun Communication Facilities (correspondents) was composed of nearly 500 people including a senior envoy, a junior envoy, other envoyes, and cooks. After preparing traveling expenses, Sifts, foods, medicinal stuffs, and ginseng, they shipped people and freight in three passenger ships and three freighters. They departed from Pusan for Edo(Tokyo). There were 28 stop-overs on their way to Edo and the banquet was given for them at every stop. The arrangements of the table for each banquet were made up of 753 Seon(tables), 3Jeup(soups) and 15Che(dishes). 753Seon(tables) is Ganban(the table for decoration) and a substantial food reception was composed of 3Jeup(soups) and 15Che(dishes). 753Seon(tables) was called Dadopoong(the food of refreshment) style and this was the standard arrangement of the banquet table in Japan. It was comprised of 3Jeup(soups) and 15Che(dishes). On their way from Edo to Thusima Island, food was afforded to correspondents for later preparation and dining. The banquet that the master of Thusima Island gave was composed of the first and second style banquets. The first one was Chusun style and the second one was Japanese style.

• 디지털융복합연구
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• 제14권12호
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• pp.583-590
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• 2016

본 연구는 동양 식품학과 서양 식품학 원리의 융합적 접근을 통해 식품의 새로운 가치를 찾아보고자 계획, 수행되었다. 이에 따라 백복령, 산약, 연육 및 검인 등 4가지 재료에 대해 기미(氣味)를 기초로 섭취효능을 정리하였고, 일반 영양성분, 무기질, 유리당 및 항산화활성을 분석하여 동 서 융합적 섭취효능에 대한 접근을 시도하였다. 동양 식품학적으로 4가지 재료들은 소화기관인 비위(脾胃)를 건강하게 하는 섭취효능이 있음을 확인하였고 서양 식품학적으로는 인의 함량이 높은 탄수화물 급원식품임을 알 수 있었다. 또한 전자공여능에 의한 자유기 소거능, ABTS 자유기 소거능, SOD 유사활성을 통해 분석한 재료들의 항산화 활성은 검인의 활성이 다른 재료들에 비해 유의적으로 높게 나타났다. 영양성분 함량 또는 기미 분석만으로는 이 재료들의 특징을 온전히 이해하기에는 한계가 있다고 보여진다. 이에 따라 식품에 대한 다양한 측면에서의 특성을 접근해 보는 시도가 필요함을 인지할 수 있다. 본 연구결과는 재료의 동 서 융합적 특성과 효능을 돌출하여 향후 이 재료들을 활용한 건강음식, 기능성 식품 등의 레시피 구성을 위한 근거자료 및 식품의 특성을 판단할 때 동 서 융합적 시각의 필요성을 인지하는데 기초자료가 되리라 사료된다.

• International Journal of Oral Biology
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• 제35권4호
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• pp.191-195
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• 2010

Oleanolic acid is a natural triterpenoid that exists widely in foods and some medicinal herbs. The purpose of this study was to determine the antimicrobial activity of oleanolic acid against Streptococcus mutans strains isolated from a Korean population. Antimicrobial activity against these bacteria was evaluated by minimal inhibitory concentration (MIC) and time kill curves. The tolerance of human gingival fibroblasts and human periodontal ligaments to oleanolic acid was tested using a methyl thiazolyl tetrazolium (MTT) assay. The $MIC_{90}$ value of oleanolic acid for both S. mutans and S. sobrinus isolated from Koreans was 8 ${\mu}g/ml$. Oleanolic acid showed bactericidal effects against S. mutans ATCC $25175^T$ and S. sobrinus ATCC $33478^T$ at $1\;{\times}\;MIC$ ($8{\mu}g/ml$) and had no cytotoxic effects against KB cells at this dose. The results suggest that oleanolic acid could be useful in the future development of oral hygiene products for the prevention of dental caries.

• Molecules and Cells
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• 제41권7호
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• pp.646-652
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• 2018

Neurodegeneration can result in memory loss in the central nervous system (CNS) and impairment of taste and smell in the peripheral nervous system (PNS). The neurodegeneration seen in Parkinson's disease (PD) is characterized by functional loss of dopaminergic neurons. Recent studies have also found a role for dopaminergic neurons in regulating taste memory rewards in insects. To investigate how taste memories and sugar sensitivity can be affected in PD, we utilized the $DJ-1{\beta}$ mutant fruit fly, $DJ-1{\beta}^{ex54}$, as a PD model. We performed binary choice feeding assays, electrophysiology and taste-mediated memory tests to explore the function of the $DJ-1{\beta}$ gene in terms of sugar sensitivity as well as associative taste memory. We found that PD flies exhibited an impaired ability to discriminate sucrose across a range of sugar concentrations, with normal responses at only very high concentrations of sugar. They also showed an impairment in associative taste memory. We highlight that the taste impairment and memory defect in $DJ-1{\beta}^{ex54}$ can be recovered by the expression of wild-type $DJ-1{\beta}$ gene in the dopaminergic neurons. We also emphasized the role of dopaminergic neurons in restoring taste memory function. This impaired memory property of $DJ-1{\beta}^{ex54}$ flies also allows them to be used as a model system for finding supplementary dietary foods that can improve memory function. Here we provide evidence that the associative taste memory of both control and $DJ-1{\beta}^{ex54}$ flies can be enhanced with dietary supplementation of the medicinal plant, omija.

• Preventive Nutrition and Food Science
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• 제9권4호
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• pp.361-366
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• 2004

Defatted methanol extracts of the medicinal plants, Rubus coreanus Miq. (RC) and Atractylodes japonica Koidzumi (AJ) were added at the levels of 0.1, 0.5, or $2\%$ (w/w) to high cholesterol diets and fed to ovariectomized Sprague-Dawley female rats, weighing 212.6 $\pm$ 1.8 g for four weeks. Weight gains were lower in RC and AJ groups than the control group, but there were no changes in uterus weights. Serum levels of triglyceride decreased by 20-$27\%$ in the experimental groups fed $0.1\%$ of each extract (O.1RC and O.1AJ), compared with that of control (Ovx). Serum cholesterol levels were not changed in the RC groups but increased in the group fed $2\%$ of the AJ extract. Liver levels of cholesterol and triglyceride were reduced in both the RC and AJ groups. Microscopic observation revealed that there were no morphological alterations in liver, lung, heart, spleen and kidney tissues of the experimental groups. Plasma levels of albumin, BUN, creatinine, sodium, potassium and phosphate in the IRC and AJ groups were in normal ranges. Serum GOT and GPT activities were, however, higher in the 2.0AJ than Ovx group. These results suggest that the extracts of the Rubus coreanus Miq. and Atractylodes japonica Koidzumi at dietary levels as low as $0.1\%$ may be utilized as hypotriglyceridemic ingredients for functional foods.

• The Korean Journal of Physiology and Pharmacology
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• 제13권2호
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• pp.85-89
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• 2009

Puerariae flos (PF) is a traditional oriental medicinal plant and has clinically been prescribed for a long time. The purpose of the present study was to examine the effect of PF on repeated stress-induced alterations of learning and memory on a Morris water maze (MWM) test in ovariectomized (OVX) female rats. The changes in the reactivity of the cholinergic system were assessed by measuring the immunoreactive neurons of choline acetyltransferase (ChAT) in the hippocampus after behavioral testing. The female rats were randomly divided into four groups: the nonoperated and nonstressed group (normal), the sham-operated and stressed group (control), the ovariectomized and stressed group (OS), and the ovariectomized, stressed and PF treated group (OSF). Rats were exposed to immobilization stress (IMO) for 14 d (2 h/d), and PF (400 mg/kg, p.o.) was administered 30 min before IMO stress. Results showed that treatments with PF caused significant reversals of the stress-induced deficits in learning and memory on a spatial memory task, and also increased the ChA T immunoreactivities. In conclusion, administration of PF improved spatial learning and memory in OVX rats, and PF may be useful for the treatment of postmenopausal-related dementia.

• 생명과학회지
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• 제18권4호
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• pp.441-446
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• 2008

본 연구는 토마토 추출물의 주방세제 유도성 건성피부에 대한 효능을 실험쥐에 식이방법과 피부도포방법으로 처리하여 확인하였다. 약 3주간의 주방세제 처리에 의한 건성 증후는 홍반의 심각한 상태를 나타내는 4정도의 visual scoring이 모든 군에서 확인되었다. 그러나 약 1주간의 토마토추출물의 식이와 피부도포를 통해 상당히 완화되거나 정상 피부에 가까운 0.7-1.0정도의 visual scoring이 확인되었다. 또한 광학현미경을 통해 건성의 또 다른 증후인 과각화 현상이 토마토추출물의 피부도포와 식이로 현저히 감소하는 것으로 확인되었다. 이러한 토마토추출물에 의한 건선성 증후의 완화는 피부 단백질 함량의 양적 변화를 유도하는 것으로 확인되어 토마토추출물의 건선성 피부의 예방과 개선에 주요한 기전으로 이해된다.

• 한국식품위생안전성학회지
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• 제36권5호
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• pp.440-446
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• 2021

GABA는 식물, 동물 및 미생물 등 자연계에 다양하게 존재하고 있으며, 항고혈압, 이뇨, 진정, 수면유도 및 항스트레스 등 다양한 효과가 있는 것으로 알려져 있어서 식품, 의약품 소재로 활용되고 있다. 본 연구에서는 김치로 부터 분리한 GABA 형성 유산균을 옥수수 수염 추출물에 적용하여 발효 특성과 발효물의 항산화 효과에 대해 분석하였다. 신규 L. plantarum LAB459의 분리와 동정은 생화학적 특성, 당자화성 및 16s rRNA 염기 서열 분석을 통해 확인되었다. 그리고 TLC와 HPLC 분석을 통해 분리된 L. plantarum LAB459가 GABA 생성능이 있는 것으로 나타났다. 그리고 탈지유가 포함된 옥수수 수염 열수 추출물에 대해 발효를 수행한 결과, 동결 건조된 발효물에 약 1 ㎍/mg 수준의 GABA가 형성된 것을 확인하였다. 또한 발효물에 대한 플라보노이드와 항산화 분석은 옥수수 수염 열수 추출물에 비해 더 높은 것으로 나타났다. 따라서 본 연구에서 분리된 L. plantarum LAB459는 다양한 식품 발효의 스타터 또는 식품 소재와 의약품 소재로 적용이 가능할 것으로 판단된다.

• Nutrition Research and Practice
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• 제13권6호
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• pp.529-534
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• 2019

BACKGROUND/OBJECTIVES: The leaves of Moringa oleifera (MO) and Moringa stenopetala (MS) commonly grown in Ethiopia possess potential nutritional and medicinal value. The aim of this study was to evaluate the nutritional and functional characteristics of the dried leaf powder from two Moringa species to develop sustainable nutritional supplements for Ethiopians from locally grown plant sources. MATERIALS/METHODS: Freshly harvested and air-dried MO and MS leaves were authenticated and the nutritional contents, such as protein, ash, lipids, and selected vitamins and minerals, were analyzed using standard analytical procedures. Amino acid compositions were also determined by an amino acid analyzer. Nine-week-old mice were randomly divided into four groups to investigate the anti-obesity effects of Moringa. The first group was fed a basal diet, the second group a high-fat diet, and the others were fed a high-fat diet containing 0.1% Moringa leaf powder from each species. After seven weeks, serum indices related to lipid profiles from each mouse were analyzed. RESULTS: The present study revealed high protein (28-29%) and ash (7-11%) contents. Glutamic acid, aspartic acid, proline, and leucine were the most abundantly found amino acids in both species. The predominant minerals in the leaf powder were calcium (826-1,530 mg/100 g), potassium (794-904 mg/100 g), and magnesium (286-431 mg/100 g). Pyridoxine (475.06 mg/100 g) and vitamin E (34.2 mg/100 g) were found only in MS. Niacin was found only in MO at 32.21 mg/100 g, whereas ascorbic acid was found in both species (3.89 and 6.19 mg/100 g dry weight for MO and MS, respectively). The results of the animal study showed that mice on a high-fat diet containing 0.1% MO leaf powder alleviated the elevation of cholesterol, triglycerides, and low-density lipoprotein cholesterol induced by the high fat diet. MO was more effective than MS in preventing hypercholesterolemia and fat deposition. CONCLUSION: The findings in this work confirmed that Moringa leaves of both MO and MS possessed high nutritional value but MO was better at preventing the harmful effects of the high-fat diet than MS.

• Fisheries and Aquatic Sciences
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• 제24권12호
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• pp.428-436
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• 2021

The aim of this study was to isolate and identify secondary metabolites from Sonchus brachyotus and evaluate their antioxidant and anti-inflammatory activities. In this study, we isolated three flavonoids from a 70% EtOH extract by Medium Pressure Liquid Chromatography (MPLC) and prep-High-Performance Liquid Chromatography (HPLC). To evaluate the biological activities (antioxidant and anti-inflammatory) of these flavonoids, their in vitro inhibitory activities against lipopolysaccharide (LPS)-induced reactive oxygen species (ROS) generation, nitric oxide (NO) production, and prostaglandin E₂ (PGE₂) secretion were determined. We successfully identified three flavonoids, namely luteolin (1), luteolin-7-O-β-D-glucoside (2), and luteolin-7-O-β-D-glucuronide (3) by spectral analyses. Luteolin (1) at 20 ㎍/mL inhibited ROS generation, NO production, and PGE₂ secretion by 48.6%, 61.28% and 12.10%, respectively, and luteolin-7-O-β-D-glucoside (2) inhibited NO and PGE₂ generation by 67.03% and 20.82%, respectively. Luteolin (1) and luteolin-7-O-β-D-glucoside (2) showed similar anti-inflammatory activities; however, luteolin (1) was observed to be a stronger antioxidant. Besides antioxidant and anti-inflammatory activities, S. brachyotus extract containing luteolin (1) and luteolin-7-O-β-D-glucoside (2) is considered to possess diverse biological activities. The results indicate that S. brachyotus is an edible medicinal plant, which is believed to be significant resource of functional foods.