• Journal of agricultural medicine and community health
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• v.24 no.1
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• pp.35-47
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• 1999

Medication non-compliance among the elderly results in medical problems and substantial cost to the health care system. This study investigate predicted variable related to the medication task ability among elderly. This study was done in the selected 4 villages in Kimchun County of Kyungbuk Province from July to August, 1996. The subject was the resident that 202 adults above 60 years of age. The questionnaire of interview included medication task ability, socio-demographic data, COOP/WONCA chart, family ABGAR score. BDI(Beck depression inventory), ADL(activities of daily living), IADL(instrumental activities of daily living), and MMSE-K(minimental state examination-Korean version). The results were as followed : 1. Approximately 49% of study population was taking drug medication currently. We found that 93% of study population was successful at the medication task all alone, 6% was failure at the medication task all alone, so need help partly or completely. 2. Significant variables between group of medication task ability were age, educational attainment, IADL, and MMSE-K in univariate analysis. And significant correlated variables with medication task ability were ADL, IADL, MMSE-K, and BDI in correlation analysis. 3. Major predictors to medication task ability on multiple logistic regression were IADL and sex finally. Findings suggest that IADL is related to medication task ability than other test battery of health status, so IADL could be used to necessary for medication management and add information to conventional methods of assessing mental status.

• The Journal of Pediatrics of Korean Medicine
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• v.23 no.1
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• pp.95-113
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• 2009

Objectives This study was investigated to find how the orally administrated Moschus, herbal combination with Moschus, and herbal combination improves the rats' memory and rats' liver. These medications are generally known asthe memory improvement. Methods This study used the Sprague Dawley rats. They were divided into two groups - SD rats and orally administrated Saline(Control group). 0.473 mg/kg Moschus(HM-A), 153.9 mg/kg herbal composition without Moschus(HM-B), and 165.95 mg/kg herbal composition with Moschus combined(HM-C) Control, saline were orally administered. Each group was trained in the eight-arm radial maze task at the conditions of before oral administrated, and also right after third, sixth, and eighth by oral administration. Lastly, these animals were killed and were tested for brain tissue and serum AST/ALT level to measure how the medications were effected to the liver function. Results The result of radial eight-arm maze task test, the HM-B and HM-C groups showed significant decrease in mistakes from the fourth day of testing. Whereas, the HM-A group showed increasing in the error rate. HM-A and HM-C group of rats had significantly increased amount of acetylcholinesterase in the CA1 region of hippocampus, compared to the control group. Whereas, HM-B and HM-C group had increased level of ChAT compared to the control group. On the other hand, each experimental group did not show any significant difference to the level of serum AST/ALT and the weight ratio of the liver to the body. Conclusions This study provided evidences that the orally administered memory improvement herbal medication, and Moschus were effective to improve memory.