• Journal of Pharmacopuncture
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• v.23 no.4
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• pp.201-211
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• 2020

Objectives: The purpose of this study is to comprehensively review Korean domestic studies and investigate the research trends of pharmacopuncture therapy on cervical pain caused by traffic accidents. Methods: Domestic studies between February 1999 and May 2020 from four Korean databases were searched with combinations of keywords 'cervical pain', 'traffic accident', 'whiplash injury', and 'pharmacopuncture'. Results: 17 studies were selected for review, including 7 randomized controlled trials, 5 retrospective observational studies, 3 case reports, and 2 non-randomized controlled trials. Each study was reviewed by published year, study type, types of pharmacopuncture solutions, selected acupuncture points, dosage of pharmacopuncture solutions, frequency of treatment, concurrent treatments, outcome measurements, and the effectiveness of pharmacopuncture therapy. The results are as follows: (1) It showed that the total number of published studies had increased slightly in the last 10 years compared to the previous decade. (2) The pharmacopuncture solutions used in the studies were in the following order: Bee-Venom (蜂毒), Jungsongouhyul (中性瘀血), Hwangryunhaedoktang (黃連解毒湯) and Soyeom (消炎). Frequently used acupuncture points were GB20, GV21, A-shi point, GV16, EX-B2, and SI15 in order. (3) The most commonly used total injection dosage was 1.0 cc at a time, and the frequency of treatment was twice a week. (4) Concurrent treatments such as acupuncture, herbal medication, physical therapy and Chuna manual therapy were performed in all 17 studies. (5) Pharmacopuncture therapy showed positive effects on cervical pain caused by traffic accidents in all 17 studies reviewed. Conclusion: Pharmacopuncture therapy was effective in cervical pain caused by traffic accidents in all 17 studies selected. Further studies will be needed using more larger scales and more objective data to confirm the effectiveness of pharmacopuncture therapy and to generalize its application.

• Journal of Korean Clinical Nursing Research
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• v.19 no.1
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• pp.105-114
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• 2013

Purpose: The purpose of this study was to apply laughter therapy to clinical practice and investigate its effects on patients' anxiety and depression in order to increase the quality of nursing for patients with inflammatory bowel disease (IBD). Methods: The study was conducted based on the non-equivalent control group pretestposttest design. The participants include 20 patients with IBD in the control group and 17 in the experiment group. Data was collected from July 10th, 2011 to January 22nd, 2012. Laughter therapy was administered once a day for five consecutive days. Results: The anxiety score was significantly different between the two groups and indicates that laughter therapy is effective for reducing anxiety among patients with IBD. Futhermore, there were differences in the depression scores of the experiment group between the pre-test and post-test, but no significant differences were found between the two groups. Conclusion: The results show that laughter therapy was effective in reducing anxiety among patients with IBD but did not decrease depression directly. Considering that the experiment group had a bigger reduction rate in depression scores than the control group. However, it is expected that laughter therapy will serve as an emotional nursing intervention for patients with IBD.

• Radiation Oncology Journal
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• v.13 no.1
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• pp.79-85
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• 1995

Purpose : To assess the efficacy of recombinant human granulocyte-macrophage colony-stimulating factor(GM-CSF) in the neutropenia by radiotherapy. Materials and Methods : Eleven patients with various solid tumor were treated with a daily subcutaneous dose of GM-CSF(3-7microgram/kg) for 5days during the radiotherapy. Before and during the course of the study all the patients were monitored by the recording of physical examination, the complete blood count with differential and reticulocyte count and liver function test. Eight patients received prior or concurrent chemotherapy. Results : In 10 patients, the neutrophilic nadir was significantly elevated and the lenght of time that Patients had a neutrophil count below $10^3/mm^3$ a threshold known to be critical to acquiring infective complications was shortened following GM-CSF injection. A significant rise (two fold or greater) of neutrophil count was seen in 10 of 11 patients. In most patients, discontinuation of GM-CSF resulted in a prompt return of granulocyte counts toward baseline. However the neutrophil count remained elevated over $10^3/mm^3$ during radiation therapy, and radiotherapy delays were avoided. Other peripheral blood components including monocytes and platelets also increased after GM-CSF treatment. No significant toxicity was encountered with subcutaneous GM-CSF treatment. Conclusion : GM-CSF was well tolerated by subcutaneous route and induced improvement in the neutropenia caused by radiotherapy.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.4
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• pp.1425-1430
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• 2012

Cyclin L2 is a novel member of the cyclin family, recently implicated in the regulation of cell cycle progression and/or transcriptional regulation. The present study was undertaken to investigate the effects of overexpression on tumor cell growth and chemosensitivity in human gastric cells in vitro. Cyclin L2 was transfected into human gastric cancer cell line BCG823 and expressed with a mammalian expression vector pcDNA3.1. The effects and mechanisms of cyclin L2 on cell growth, cell cycling and apoptosis were studied. Compared to control vectors, overexpression of cyclin L2 inhibited the growth of BCG823 cells and enhance their chemosensitivity to fluorouracil, docetaxel and cisplatin. The anti-proliferative effects of cyclin L2 could be due to G0/G1 arrest and apoptosis. Cyclin L2 induced G0/G1 arrest and apoptosis involved upregulation of caspase-3 and down regulation Bcl-2 and survivin. The results indicated that overexpression of cyclin L2 protein may promote efficient growth inhibition and enhance chemosensitivity to chemotherapeutic agents in human gastric cancer cells by inducing G0/G1 cell cycle arrest and apoptosis.

• Journal of the Korean Society of Physical Medicine
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• v.14 no.1
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• pp.53-61
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• 2019

PURPOSE: This study examined the dynamic range of motion (ROM) of the hip, knee, and ankle joint when wearing different shoe sole lifts, as well as the limb asymmetry of the range according to the leg length discrepancy (LLD) during normal speed walking. METHODS: The participants were 40 healthy adults. A motion analysis system was used to collect kinematic ROM data. The participants had 40 markers attached to their lower extremities and were asked to walk on a 6 m walkway, under three different shoe lift conditions (without an insole, 1 cm insole, and 2 cm insole). Visual3D professional software was used to coordinate kinematic ROM data. RESULTS: Most of the ROM variables of the short limbs were similar under each insole lift condition (p>.05). In contrast, when wearing a shoe with a 2 cm insole lift, the long limbs showed significant increases in flexion and extension of the knee joint as well as; plantarflexion, dorsiflexion, pronation, eversion, and inversion of the ankle joint (p<.05). Of the shoes with the insole lifts, significant differences in all ROM variables were observed between the left and right knees, except for the knee internal rotation (p<.05). CONCLUSION: As the insole lift was increased, more ROM differences were observed between the left and right limbs, and the asymmetry of the bilateral lower limbs increased. Therefore, appropriate interventions for LLD are needed because an artificial mild LLD of less than 2.0 cm could lead to a range of musculoskeletal problems of the lower extremities, such as knee and ankle osteoarthritis.

• Journal of Multimedia Information System
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• v.5 no.3
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• pp.171-178
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• 2018

According to the National Health Insurance Corporation in 2008, there were 17,764,428 physical therapy patients, exceeding 31 percent for the population covered by health insurance. This means that three out of 10 Koreans received physical therapy. And now, 10 years later, due to the aging population and the increase in the sports population, the number of patients with physical therapy is expected to be much more than a decade ago. Among them, many physical therapy patients were orthopedic and neurologic disorder. However, in the medical field applied to physical therapy, it is widely applied across all medical fields, including orthopedics, neurosurgery, pediatrics, gynecology, thoracic surgery and dentistry. It is believed that various cases of patients receiving physical therapy will be secured. as mentioned earlier, there will be a large number of patients with physical therapy treatments, making big data analytics easier. based on this, physical therapy applications are thought to be helpful in the analogy of disease and the development of effective physical therapy and will ultimately promote the development of physical therapy.

• Journal of Korean Medical Ki-Gong Academy
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• v.19 no.1
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• pp.1-24
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• 2019

Objective : The purpose of this study is to understand a medical Gigong's view of the human body through the analysis of medical Gigong techniques, and to understand the concept and treatment principle of Whidam's Su-Gi therapy as the Angyo(按蹻) Method of Doin Angyo(導引 按蹻) Methods : Among Medical Gigong, Sojucheon practice, Moosim-Gigong Riding stance, Moosim-Gigong Doinbeop, Hwalinsimbang Doinbeop and Donguibogam Jang-Bu Doinbeop were selected to analyze the practice method. The medical Gigong's views of the human body are organized into overviews and pathological perspective. The main concepts and clinical techniques of Whidam's Su-Gi therapy were summarized. Discussion : Understanding the principles of medical Gigong is necessary in order to understand the Angyo method of Doin Angyo. The principle of medical Gigong is to circulate around Three-Danjeon(丹田) on the human belly and Three-Gwan(關) on the human back by practicing medical Gigong, and to strengthen the life force by activating the viscera function by communicating between the limbs and the body. If there are Jeokchwi(積聚) and deviation, Whidam's Su-Gi therapy eliminates the Jeokchwi and adjusts the deviation. Conclusions : 1. The Angyo method of Doin Angyo originates from the practice of training to establish Danjeon for the right body and the right flow of air. 2. The principles of medical Gigong obtained through the analysis of Sojucheon(小周天) practice, Moosim-Gigong Riding stance, Moosim-Gigong Doinbeop, Hwalinsimbang Doinbeop and Donguibogam Jang-Bu Doinbeop are the medical Gigong's view of the human body and pathological perspective. 3. Whidam's Su-Gi therapy, which focuses on the elimination of Jeokchwi and the adjustment of deviation based on the medical Gigong's view of the human body, is a manual therapy that inherits the principle of the Angyo Method of Doin Angyo.

• Radiation Oncology Journal
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• v.16 no.3
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• pp.347-350
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• 1998

Purpose : This study is to see how much proportion of the patients receiving radiation therapy drop out during radiation therapy and to analyze the reason for the incomplete treatment. Materials and Methods : The base population of this study was 1,100 patients with registration numbers 901 through 2,000 at Department of Radiation Oncology, Samsung Medical Center, Seoul, Korea. Authors investigated the incidence of incomplete radiation therapy, which was defined as less than 95$\%$ of initially planned radiation dose, and the reasons for incomplete radiation therapy. Results : One hundred and twenty eight patients (12$\%$) did not complete the planned radiation therapy. The performance status of the incompletely treated patients was generally Poorer than that of the base population, and the aim of radiation therapy was more commonly palliative. The most common reason for not completing the planned treatment was the patients' refusal of further radiation therapy because of the distrust of radiation therapy and/or the poor economic status. Conclusion : Careful case selection for radiation therapy with consideration of the socioeconomic status of the patients in addition to the clinical indication would be necessary for the reduction of incomplete treatment, especially in the palliative setting.

• Physical Therapy Korea
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• v.30 no.1
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• pp.50-58
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• 2023

Background: This study was carried out to determine whether non-face-to-face physical therapy would have similar exercise effects to face-to-face physical therapy. Hence, we developed an approach for patients, unable to visit hospitals due to circumstances such as the COVID-19 pandemic, to conduct physical therapy comfortably at home. Objects: This study aimed to compare the effects of a face-to-face and a non-face-to-face physical therapy treatment on improving a rounded shoulder posture. Methods: The participants with rounded shoulders were randomly divided into a face-toface group (n = 15) and a non-face-to-face group (n = 15), and each group performed exercises for four weeks. The exercise program consisted of the bare hands exercise, Thera-Band exercise, and foam roller exercise. The participants in the face-to-face group came to a designated place to perform their exercises, and those in the non-face-to-face group performed the exercises at their own home using Google Meet (Google). Acromial height, total scapular distance (TSD), shoulder pain and dysfunction index (SPADI), and pectoralis minor thickness were measured. Data analysis was performed using the R Statistical Software (R Core Team), and a normality test was performed using the Shapiro-Wilk test. Results: There were no significant differences between the face-to-face and the non-face-toface groups (p > 0.05). When comparing the differences before and after the exercises, both the face-to-face and the non-face-to-face groups showed significant differences in acromial height, SPADI, and pectoralis minor thickness (p < 0.05), and both groups showed no significant difference in TSD before and after the exercises (p > 0.05). Conclusion: The results of this study support the results of previous studies reporting that shoulder stabilization exercise and pectoralis minor stretching training improves round shoulders. In addition, this study revealed that both the face-to-face and the non-face-to-face physical therapy treatments had therapeutic effects.

• Journal of Oriental Neuropsychiatry
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• v.27 no.2
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• pp.67-76
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• 2016

Objectives The purpose of this study is to report that a patient with obsessive-compulsive disorder (OCD) significantly responds to Korean medical treatments and psychotherapy.Methods We treated the patient with Korean medical treatments (acupuncture and herbal medication) and Melonis Calyx Vomiting Therapy. We also used psychotherapy including Li-Gyeung-Byun-Qi therapy. The patient was diagnosed by DSM-IV diagnostic criteria for OCD. We used Obsessive-Compulsive Inventory-Revised-Korean (OCI-R-K), Visual Analogue Scale (VAS), Beck’s Depression Inventory (BDI), and Beck’s Anxiety Inventory (BAI) to evaluate the patient.Results OCI-R-K score was decreased from 39 points to 9 points. BDI score was decreased from 14 points to 6 points. BAI score was decreased from 25 points to 13 points.Conclusions This study suggests that Korean medical treatment is an effective way to treat patients who suffer from OCD.