• Title/Summary/Keyword: Medical simulation

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A Distributed address allocation scheme based on three-dimensional coordinate for efficient routing in WBAN (WBAN 환경에서 효율적인 라우팅을 위한 3차원 좌표 주소할당 기법의 적용)

  • Lee, Jun-Hyuk
    • Journal of Digital Contents Society
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    • v.15 no.6
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    • pp.663-673
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    • 2014
  • The WBAN technology means a short distance wireless network which provides each device interactive communication by connecting devices inside and outside of body. Standardization on the physical layer, data link layer, network layer and application layer is in progress by IEEE 802.15.6 TG BAN. Wireless body area network is usually configured in energy efficient using sensor and zigbee device due to the power limitation and the characteristics of human body. Wireless sensor network consist of sensor field and sink node. Sensor field are composed a lot of sensor node and sink node collect sensing data. Wireless sensor network has capacity of the self constitution by protocol where placed in large area without fixed position. In this paper, we proposed the efficient addressing scheme for improving the performance of routing algorithm by using ZigBee in WBAN environment. A distributed address allocation scheme used an existing algorithm that has wasted in address space. Therefore proposing x, y and z coordinate axes from divided address space of 16 bit to solve this problems. Each node was reduced not only bitwise but also multi hop using the coordinate axes while routing than Cskip algorithm. I compared the performance between the standard and the proposed mechanism through the numerical analysis. Simulation verified performance about decrease averaging multi hop count that compare proposing algorithm and another. The numerical analysis results show that proposed algorithm reduced the multi hop better than ZigBee distributed address assignment

Additive hazards models for interval-censored semi-competing risks data with missing intermediate events (결측되었거나 구간중도절단된 중간사건을 가진 준경쟁적위험 자료에 대한 가산위험모형)

  • Kim, Jayoun;Kim, Jinheum
    • The Korean Journal of Applied Statistics
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    • v.30 no.4
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    • pp.539-553
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    • 2017
  • We propose a multi-state model to analyze semi-competing risks data with interval-censored or missing intermediate events. This model is an extension of the three states of the illness-death model: healthy, disease, and dead. The 'diseased' state can be considered as the intermediate event. Two more states are added into the illness-death model to incorporate the missing events, which are caused by a loss of follow-up before the end of a study. One of them is a state of the lost-to-follow-up (LTF), and the other is an unobservable state that represents an intermediate event experienced after the occurrence of LTF. Given covariates, we employ the Lin and Ying additive hazards model with log-normal frailty and construct a conditional likelihood to estimate transition intensities between states in the multi-state model. A marginalization of the full likelihood is completed using adaptive importance sampling, and the optimal solution of the regression parameters is achieved through an iterative quasi-Newton algorithm. Simulation studies are performed to investigate the finite-sample performance of the proposed estimation method in terms of empirical coverage probability of true regression parameters. Our proposed method is also illustrated with a dataset adapted from Helmer et al. (2001).

EEG 16 channel variations between the non-stimulation and the moxibustion stimulated subjects for CV4, CV8, and CV12 acupuncture points (중완, 신궐 및 관원 경혈의 뜸 자극과 무 자극 대상군의 16채널 뇌파 변화에 관한 연구)

  • Yoon, Dong-Eop;Song, Hong-Bok
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.12
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    • pp.2755-2760
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    • 2010
  • The moxibustion therapy of orient medical is well known. Moxibustion method is used to burning moxibustion. The variation factors of the moxibustion stimulation for body can be applied to the electronic moxibustion method. This study is to analyze and examine the electroencephalogram(EEG) variations for moxibustion stimulation. In experiment, we divided six healthy male subjects into two same sized groups : with and without stimuli. The given stimuli are the moxibustion for CV4(Kwan-Won), CV8(Shin-Guel), and CV12(Jung-wan) acupuncture points. We have analyzed the power spectrum for ${\alpha}$, ${\beta}$, ${\delta}$, ${\Theta}$ waves and the average EEG variation level and each channels variation level of EEG. The result was that the moxibustion stimulation decreased the EEG levels of parietal lobe(ch 2, 3, 6, 7) according to the somatosensory system. And the apparent different points are that mild-heat($42{\sim}44^{\circ}C$) stimulation generating ${\alpha}$-wave is increased and ${\beta}$-wave is decreased, also slight-hot($45{\sim}48^{\circ}C$) stimulation made ${\alpha}$-wave decrease and ${\beta}$-wave increase for occipital lobe(ch 4,8) on the simulation group.

A study on the event processing methods for ubiquitous sensor network (유비쿼터스 센서 네트워크를 위한 이벤트 처리 기법에 관한 연구)

  • Cho, Yang-Hyun;Park, Yong-Min;Kim, Hyeon-Gyu
    • Journal of the Korea Society of Computer and Information
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    • v.18 no.1
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    • pp.137-147
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    • 2013
  • The RFID(Radio Frequency Identification) and the WSN(Wireless Sensor Network) have technical similarities and mutual effects, they have been recognized to be studied separately, and sufficient studies have not been conducted on the technical integration of the RFID and the WSN. Therefore, EPC global which realized the issue proposed the EPC(Electronic Produce Code) Sensor Network to efficiently integrate and interoperate the RFID and WSN technologies based on the international standard EPC global network. The proposed EPC Sensor Network technology uses the Complex Event Processing method in the middleware to integrate data occurring through the RFID and the WSN in a single environment and to interoperate the events based on the EPC global network. However, as the EPC Sensor Network technology continuously performs its operation even in the case that the minimum conditions are not to be met to find complex events in the middleware, its operation cost rises. Therefore, to address the problems of the existing system, we defined the minimum conditions of the complex events to detect unnecessary complex events in the middleware, and proposed an algorithm that can extract complex events only when the minimum conditions are to be met. To examine the minimum conditions, a index and a query index are used to extract complex events. To evaluate the performance of the proposed methods, In the case of the method of extracting complex events based on a bitmap index, we used the existing extraction method and NS2 simulation to evaluate its performance and thus to show its good performance in terms of the number of operation and the processing time for the complex events.

The Impact of Population Aging on Energy Use and Carbon Emissions in Korea (인구 고령화가 에너지 사용과 탄소 배출에 미치는 영향)

  • Kim, Dong Koo;Park, Sunyoung
    • Journal of Environmental Policy
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    • v.13 no.2
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    • pp.99-129
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    • 2014
  • This research estimates the impact of population aging on energy use and carbon emissions by energy sources and by industrial sectors in Korea until 2035. For the estimation, the structural change in household consumption expenditure identified by the age-specific consumption pattern was analyzed in conjunction with energy and environment input-output tables. The estimation result presents that, despite the population aging, energy use and carbon emissions induced by household consumption continue to increase until 2026, and then that elevated levels of energy use and carbon emissions will be maintained for a considerable period of time. According to the estimation by energy sources, the use of natural gas will show substantial increase while the use of crude oil will switch to a downturn at a relatively early period. According to the estimation by industrial sectors, carbon emissions in the sectors with relatively high consumption share of old households such as medical health, dwelling, lighting, heating, air-conditioning, and food will have substantial increase, whereas those in the sectors associated with education, transport, catering, and accommodation services will turn downward relatively early. In addition, the study analyzes through policy simulation the impact of aging-related policy similar to the basic pension system, which is recently being discussed for legislation, on energy use and carbon emissions.

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Grand Average in MEG and Crude Estimation of Anatomical Site (뇌자도에서 전체 평균과 이를 이용한 해부학적 위치 추정)

  • Kwon H.;Kim K.;Kim J. M.;Lee Y. H.;Park Y. K.
    • Journal of Biomedical Engineering Research
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    • v.25 no.6
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    • pp.575-580
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    • 2004
  • In this work, a method is presented to find an anatomical site of a current source crudely in a standard brain using grand average of MEG data. Minimum norm estimation algorithm and truncated singular value decomposition were applied to calculate the distributed sources that can reproduce the measured signals. Grand average over all subjects was obtained from the transformed signals, which would be detected in a standard sensor plane by the obtained distributed current sources. In the simulation study, it was shown that the localized dipole using the grand average is consistent with the mean location of localized dipoles of all subjects within several mm even with large inter-individual differences of sensor positions. This result suggests that the mean location of low level signal source can be estimated as a dipole source in grand average and it was confirmed in the localization of the current source of N100m. when the localized dipole is registered on a standard brain. This result also suggests that the activity region obtained from grand average can be crudely estimated on a standard brain using the source location of the N100m as a reference point.

Development of Target-Controlled Infusion System in Plasma Concentration. PART1 : Establishment of Pharmacokinetic Model and Verification (혈중 목표 농도 자동 조절기(TCI) 개발 PART1 : 약동학적 모델의 수립과 검증)

  • 안재목;길호영
    • Journal of Biomedical Engineering Research
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    • v.23 no.5
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    • pp.341-349
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    • 2002
  • The target controlled infusion(TCI) pump system is a logical approach to the development of improved administration techniques of an intravenous anaesthetic agent. The principle of TCI system is based on an understanding of the pharmacokinetic properties, three or four compartment model. The TCI system is optimal and flexible control of the plasma drug concentration. But the clinical goal is always to achieve a therapeutic drug effect, not a therapeutic concentration. So we developed the algorithm to target the concentration at the site of drug effect rather than the concentration in the plasma. If impulse drug is inputted into body, the decline of plasma concentration with time is shown, resulting in the expression of the differential equation. Therefore, we must reformulate our three-compartment model as four-compartment model with the effect compartment. And we tested plasma targeting and effect targeting algorithm by computer simulation using four-compartment model. So we developed the TCI capable of applying all intravenous drugs by adjusting individual pharmacokinetic parameters independently.

Analysis of Oscillometric Model based on Shape of Arterial Pressure (동맥압 형태를 고려한 오실로메트릭 모델분석)

  • 임성수;이경중
    • Journal of Biomedical Engineering Research
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    • v.21 no.4
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    • pp.411-417
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    • 2000
  • This paper describes the analysis of the oscillometric method based on the shape of arterial pressure and proposal of a new algorithm for estimating the blood pressure by computer simulation. In the first step, the arterial pressure model which is able to control the shape of arterial pressure was designed and then we simulated the oscillometric model using both the existing exponential model showing the static arterial pressure-volume relation and the designed arterial pressure model. By analyzing the correlation of characteristic ratio based on the shape of arterial pressure, we could find that the characteristic ratio was not the only standard parameter for estimating systolic and diastolic pressure. We were able to estimate the shape of arterial pressure by computing the correlation of arterial pressure shape with oscillation shape. Finally, we proposed an algorithm which is able to estimate systolic and diastolic pressure according to pressure(Pp) table constructed from the relation of maximum amplitude of oscillation and arterial pressure shape. We tested 60 arterial pressure waveforms having various arterial pressure shape and pulse. As a results, the absolute deviation average values of the estimation of systolic, diastolic and mean pressure were 1.62%, 2.40% and 2.20%, respectively. In conclusions, the proposed algorithm showed the possibility of usefullness in estimating the blood pressure.

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Calibration of CR-39 for Hadron Radiotherapy using 400 MeV/u C ions (400 MeV/u 탄소 이온에 대한 방사선치료 선량 측정용 고체비적검출기의 교정)

  • Kim, Sunghwan;Nam, Uk-Won;Lee, Jaejin;Park, Won-Kee;Pyo, Jeonghyun;Moon, Bong-Kon
    • Journal of radiological science and technology
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    • v.39 no.1
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    • pp.43-49
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    • 2016
  • In this study, equivalent dose and LET (Linear Energy Transfer) calibration of CR-39 SSNTD (Solid State Nuclear Track Detector) were performed using 400 MeV/u C heavy ions in HIMAC (Heavy Ion Medical Accelerator in Chiba) for high LET radiation therapy. The irradiated CR-39 SSNDTs were etched according the etching condition of JAXA (Japan Aerospace Exploration Agency). And the etched SSNTDs were analyzed by using Image J. Determined frequency mean dose (${\bar{y_D}}$)and dose-mean lineal energy (${\bar{y_F}}$)of 400 MeV/u C are about 8.5keV/mm and 10.1 keV/mm, respectively by using the CR-39 SSNTD. This value is very similar to the results calculated by GEANT4 Monte Carlo simulation and measured with TEPC (Tissue Equivalent Proportional Counter) active radiation detector. We could determine the equivalent dose and LET calibration factors of CR-39. And we confirmed that the CR-39 SSNTD was useful for high LET radiation dosimetry in hadron radiotherapy.

A Finite Element Simulation of Cancellous Bone Remodeling Based on Volumetric Strain (스폰지 뼈의 Remodeling 예측을 위한 체적 변형률을 이용한 유한요소 알고리즘)

  • Kim, Young;Vanderby, Ray
    • Journal of Biomedical Engineering Research
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    • v.21 no.4
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    • pp.373-384
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    • 2000
  • The goal of this paper is to develop a computational method to predict cancellous bone density distributions based upon continuum levels of volumetric strain. Volumetric strain is defined as the summation of normal strains, excluding shear strains, within an elastic range of loadings. Volumetric strain at a particular location in a cancellous structure changes with changes of the boundary conditions (prescribed displacements, tractions, and pressure). This change in the volumetric strain is postulated to predict the adaptive change in the bone apparent density. This bone remodeling theory based on volumetric strain is then used with the finite element method to compute the apparent density distribution for cancellous bone in both lumbar spine and proximal femur using an iterative algorithm, considering the dead zone of strain stimuli. The apparent density distribution of cancellous bone predicted by this method has the same pattern as experimental data reported in the literature (Wolff 1892, Keller et al. 1989, Cody et al. 1992). The resulting bone apparent density distributions predict Young's modulus and strength distributions throughout cancellous bone in agreement with the literature (Keller et al. 1989, Carter and Hayes 1977). The method was convergent and sensitive to changes in boundary conditions. Therefore, the computational algorithm of the present study appears to be a useful approach to predict the apparent density distribution of cancellous bone (i.e. a numerical approximation for Wolff's Law)

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