• Journal of Periodontal and Implant Science
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• 제35권4호
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• pp.1003-1017
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• 2005

이 논문은 단일조사 저출력 $CO_2$ Laser조사가 치주인대 섬유아세포의 증식과 분화에 미치는 영향을 살펴보고 가장 효과적인 에너지와 파워밀도(power density)를 알아보기 위해 다음과 같이 실험하였다. 0.5W 출력, 10.6 ${\mu}m$ 파장, 50 Hz 연속형 $CO_2$ Laser를 사용하여, 실험군은 laser tip과 배양된 세포 사이의 거리를 2cm, 3cm으로 나누고, 조사시간을 1초, 3초로 나누어 4개의 군으로 설정하였고 대조군은 laser를 조사하지 않은 군으로 하였다. 치주인대 섬유아세포의 증삭정도와 골모세포로의 분화정도를 보기 위하여 각각 MTT 실험과 ALP activity 실험을 시행하여 다음과 같은 결과를 얻었다. 1. Laser를 조사하고 난 후 5일째에, 모든 군에서 유의하게 세포가 증식되는 것을 확인할 수 있었고 조사방법간에 유의한 차이가 없었다. 2. 대조군과 살험군에서 0일째에 비하여 3일째, 5일째, 7일째, 10일째에 통계적으로 유의 하게 ALP activity가 증가하였고, 이중 2cm,1sec 군을 제외하면 3일째에서 가장 높은 ALP activity 값을 보였다. 특징적으로 2cm,1sec 군은 3일째부터 10일까지 통계적으로 유의하지는 않지만 시간이 지남에 따라서 ALP activity가 증가함을 보였다. 7일과 10일째에는 2cm,1sec, 3cm,3sec군에서 다른 군에 비하여 큰 activity값을 보였다. 이번실험에서 저출력 $CO_2$ Laser 조사는 세포의 증식보다는 분화에 더 큰 영향을 끼쳤고, 2cm, 1sec, 3cm, 3sec 군이 치주인대 섬유아세포의 분화에 가장 효과적인 laser 조사방법으로 분석되었다.

• The Journal of Korean Physical Therapy
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• 제22권6호
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• pp.77-83
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• 2010

Purpose: The aim of this study was to do numerical analysis of the wavelength dependence in low level laser therapy (LLLT) using a finite element method (FEM). Methods: Numerical analysis of heat transfer based on a Pennes' bioheat equation was performed to assess the wavelength dependence of effects of LLLT in a single layer and in multilayered tissue that consists of skin, fat and muscle. The three different wavelengths selected, 660 nm, 830 nm and 980 nm, were ones that are frequently used in clinic settings for the therapy of musculoskeletal disorders. Laser parameters were set to the power density of 35.7 W/$cm^2$, a spot diameter of 0.06 cm, and a laser exposure time of 50 seconds for all wavelengths. Results: Temperature changes in tissue based on a heat transfer equation using a finite element method were simulated and were dominantly dependent upon the absorption coefficient of each tissue layer. In the analysis of a single tissue layer, heat generation by fixed laser exposure at each wavelength had a similar pattern for increasing temperature in both skin and fat (980 nm > 660 nm > 830 nm), but in the muscle layer 660nm generated the most heat (660 nm ${\gg}$ 980 nm > 830 nm). The heat generation in multilayered tissue versus penetration depth was shown that the temperature of 660 nm wavelength was higher than those of 830 nm and 980 nm Conclusion: Numerical analysis of heat transfer versus penetration depth using a finite element method showed that the greatest amount of heat generation is seen in multilayered tissue at = 660 nm. Numerical analysis of heat transfer may help lend insight into thermal events occurring inside tissue layers during low level laser therapy.

• 한방안이비인후피부과학회지
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• 제28권2호
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• pp.112-120
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• 2015

Purpose : To observe effects of TKM (Traditional Korean Medicine) treatment for 2 patients who had verruca plana after having laser epilation of leg hair. Methods : We did retrospective chart review for 2 verucca plana patients who had been treated by TKM. TKM treatment included herbal treatment, herbal acupuncture and herbal ointment. Results : After TKM treatment, the patients' verucca plana remarkably disappeared and there was no recurrence. Conclusion : This study suggest that TKM may be an effective treatment for verucca plana.

• 산업기술연구
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• 제26권B호
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• pp.35-41
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• 2006

Recently, as ultrasonic medical devices are gradually developed, many of those requires smaller and more precision coaxial cables in probe. So, the use of micro coaxial cable becomes an efficient solution for ultrasonic machine. However, there are many difficulties in stripping micro coaxial cable by traditional mechanical process. In this paper, we use the Nd-YAG laser for the efficient stripping of conduct wire of cable. We propose a new method to strip the shield wire of micro coaxial cable. Through some experiments, we found that there is a new possibility in the proposed method. Also, in order to enhance the performance, we propose a preprocess of the cable before stripping.

• 한국정밀공학회지
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• 제26권9호
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• pp.64-71
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• 2009

Recently as ultrasonic medical devices are gradually developed, many of those require smaller and more precision coaxial cables in the probe. So, the use of micro coaxial cable becomes an efficient solution for ultrasonic machine. However, there are many difficulties in stripping micro coaxial cable by traditional mechanical process. In this paper we use the Nd:YAG laser for the efficient striping of conduct wire of cable. Through some experiments, we found that there is a new possibility in the proposed method. Also, we propose a pre-process of the cable before stripping in order to enhance the performance.

• Medical Lasers
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• 제8권2호
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• pp.97-100
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• 2019

Facial pores are a visible topographic feature of skin surfaces and are generally the enlarged openings of pilosebaceous follicles. Enlarged facial pores can be a significant cosmetic problem, particularly for women. Recently, gold nanoshell-mediated photothermal therapy (PTT) has been reported to be effective in treating recurrent acne. The treatment of enlarged facial pores with gold nanoshell-mediated PTT produced excellent results with no side effects. The two cases reported here demonstrate the possibility of gold nanoshell-mediated PTT as a safe and effective treatment for enlarged facial pores.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.385-387
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• 1997

Plasma luminescence spectroscopy was used or precise ablation of bone tissue during ultrashort pulse laser (USPL) micro-spinal surgery. Strong contrast of the luminescence spectra between bone marrow and spinal cord provided the real time feedback control so that only bone tissue can be selectively ablated while preserving the spinal cord.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2015년도 제49회 하계 정기학술대회 초록집
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• pp.140.1-140.1
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• 2015

Currently, As Plasma application is expanded to the industrial and medical industrial, Low temperature plasma characteristics became important. Especially in Medical industrial, Low temperature plasma directly adapted to human skin, so their plasma parameter is important. One of the plasma parameters is electron density, some kinds of method to measuring electron density are Thomson scattering spectroscopy and Millimeter-wave transmission measurement. But most methods is expensive to composed of experiment system. Heterodyne interferometer system is cheap and simple to setting up, So we tried to measuring electron density by Laser heterodyne interferometer. To measuring electron density at atmospheric pressure, we need to obtain the phase shift signal. And we use a heterodyne interferometer. Our guiding laser is Helium-Neon laser which generated 632 nm laser. We set up to chopper which can make a laser signal like a pulse. Chopper can make a 4 kHz chopping. We used Needle jet as Ne plasma sources. Interference pattern is changed by refractive index of electron density. As this refractive index change, phase shift was occurred. Electron density is changed from Townsend discharge's electron bombardment, so we observed phenomena and calculated phase shift. Finally, we measured electron density by refractive index and electron density relationship. The calculated electron density value is approximately 1015~1016 cm-3. And we studied electron density value with voltage.

• Journal of the Optical Society of Korea
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• 제15권4호
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• pp.373-379
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• 2011

Current therapeutic methods for suppressing muscle spasticity are intensive functional training, surgery, or pharmacological interventions. However, these methods have not been fully supported by confirmed efficacy due to the aggravation of the muscle spasticity in some patients. In this study, a combined system was developed to treat with a low-level laser and to monitor the region of the treatment using an optical spectroscopic probe that measures oxygen saturation and deoxygenation during low-level laser therapy (LLLT). The evaluation of the wavelength dependence for LLLT was performed using a Monte Carlo simulation and the results showed that the greatest amount of heat generation was seen in the deep tissue at ${\lambda}$ = 830 nm. In the oxy- and deoxygenation measurements during and after the treatment, oxygen-Hb concentration was significantly increased in the laser-irradiated group when compared to the control group. These findings suggest that LLLT using ${\lambda}$ = 830 nm may be of benefit in accelerating recovery of muscle spasticity. The combined system that we have developed can monitor the physiological condition of muscle spasticity during the laser treatment in real time and may also be applied to various myotonia conditions such as muscle fatigue, back-pain treatment/monitoring, and ulcer due to paralysis.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 추계학술대회 논문집 Vol.21
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• pp.397-398
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• 2008

This paper performed the basic study for fabricating the low level laser therapy apparatus, and one of the goals of this paper was to make this apparatus used handily. The apparatus has been fabricated using the 655nm laser diode and microprocessor unit. The apparatus used a 655 nm laser diode for laser medical therapy and was designed for a pulse width modulation type to increase stimulation effects. And then, each experiment was performed to irradiation group and non-irradiation group for cells. MTT assay method was chosen to verify the cell increase of two groups and the effect of irradiation on cell proliferation was examined by measuring 590nm transmittance of ELISA reader. As a result, the cell increase of cells was verified in irradiation group as compared to non-irradiation group.