• Toxicological Research
• /
• 제34권3호
• /
• pp.199-210
• /
• 2018

Skeletal muscle can be ultrastructurally damaged by eccentric exercise, and the damage causes metabolic disruption in muscle. This study aimed to determine changes in the metabolomic patterns in urine and metabolomic markers in muscle damage after eccentric exercise. Five men and 6 women aged 19~23 years performed 30 min of the bench step exercise at 70 steps per min at a determined step height of 110% of the lower leg length, and stepping frequency at 15 cycles per min. $^1H$ NMR spectral analysis was performed in urine collected from all participants before and after eccentric exercise-induced muscle damage conventionally determined using a visual analogue scale (VAS) and maximal voluntary contraction (MVC). Urinary metabolic profiles were built by multivariate analysis of principal component analysis (PCA) and orthogonal partial least square-discriminant analysis (OPLS-DA) using SIMCA-P. From the OPLS-DA, men and women were separated 2 hr after the eccentric exercise and the separated patterns were maintained or clarified until 96 hr after the eccentric exercise. Subsequently, urinary metabolic profiles showed distinct trajectory patterns between men and women. Finally, we found increased urinary metabolites (men: alanine, asparagine, citrate, creatine phosphate, ethanol, formate, glucose, glycine, histidine, and lactate; women: adenine) after the eccentric exercise. These results could contribute to understanding metabolic responses following eccentric exercise-induced muscle damage in humans.

• 대한물리의학회지
• /
• 제13권4호
• /
• pp.85-94
• /
• 2018

PURPOSE: This study was conducted to determine the effects of therapeutic exercise on range of motion (ROM), the manual muscle test (MMT), functional movement screen (FMS) and radiological evaluation in a youth football player with football-specific anterior pelvic tilt (APT). METHODS: The subject of this case report was a 12-year-old youth football player, who presented with football-specific APT. Therapeutic exercise consisted of hamstring stretch, prone hip extension, abdominal crunch, bridging with isometric hip abduction, plank exercise with posterior tilt and posterior pelvic tilting exercise using a swiss-ball for 40 min/day, twice a week for 8-weeks. ROM, MMT, FMS (deep squat, hurdle step, inline lunge, shoulder mobility, active straight-leg raise, rotary stability and trunk stability push-up) and radiographs (lumbar lordotic and sacral horizontal angle) were analyzed before and after week 8 of therapeutic exercise. RESULTS: The ROM, MMT, and FMS increased and the lumbar lordotic angle and sacral horizontal angle improved after 8-weeks of therapeutic exercise. CONCLUSION: The results of this case report suggest that therapeutic exercise improves ROM, MMT and radiography associated parameters in youth football players with football-specific APT. These findings have clinical implications for therapeutic exercise in youth football players with football-specific APT.

• 대한물리의학회지
• /
• 제16권1호
• /
• pp.111-121
• /
• 2021

PURPOSE: This study examined the effects of core stability exercise on the strength, activation of the trunk muscle, and pulmonary function in a Guillain-Barre syndrome (GBS) patient. METHODS: A 38-year-old male with GBS was enrolled in the study. A core stability exercise program was implemented for four weeks with a duration of 30 min/day and a frequency of three days/week. The program consisted of abdominal crunch, Swiss ball crunch, bicycle crunch, medicine ball sit-up with a toss, medicine ball rotational chest pass, raised upper body and lower body, and dead bug. Measurements of the strength of the trunk muscle (trunk flexion and hip flexion), activation of trunk muscles (rectus femoris; RA, external oblique abdominal; EOA, internal oblique abdominal; IOA, erector spinae; ES), and pulmonary function (forced expiratory capacity; FVC, forced expiratory volume at one second; FEV1) were taken before and after four weeks of core stability exercise. RESULTS: The strength of trunk muscles increased in the trunk and hip flexion after four weeks of core stability exercise, respectively, compared to the baseline levels. Activation of the trunk muscles increased in RA, EOA, and IOA after four weeks of core stability exercise compared to baseline levels, but decreased in ES after four weeks of core stability exercise compared to the baseline levels. The pulmonary function increased in FVC and FEV1 after four weeks of core stability exercise compared to the baseline levels. CONCLUSION: These results suggest that core stability exercise improves strength, Activation of the trunk muscle, And pulmonary function in patients with GBS.

• The Journal of Korean Physical Therapy
• /
• 제32권1호
• /
• pp.21-28
• /
• 2020

Purpose: This study identified the effects of physical therapists on the quality of life when applying exercise-based movement techniques to breast cancer survivors. Methods: To conduct meta-analysis, 186 RCT studies were searched in five databases (RISS, Pubmed, CINAHL, Medline, and Cochrane Library), without limitation, for the year of publication, and papers published in April 2018 were selected. Four studies met the inclusion criteria and were selected for meta-analysis based on the risk of bias. The basic demographic data, athletic characteristics, and outcome data were extracted from all included clinical trials. The data were analyzed using the RevMan 5.2 program. Results: As a result of meta-analysis, exercise-based movement techniques applied by the control group (Pilates, yoga, tai chi, and qigong) or physical therapists showed no significant difference in the impact on the quality of life of breast cancer survivors. Conclusion: In this study, exercise-based movement techniques mediated by control groups or physical therapists showed no significant difference in the quality of life of breast cancer survivors, but the types and duration of exercise in each study varied, and the number of subjects was small. Considering randomized studies, more randomized studies will be needed to draw conclusions.

• PNF and Movement
• /
• 제17권3호
• /
• pp.353-368
• /
• 2019

Purpose: This study investigated the effects of trunk exercise using less-affected extremities on gait and balance in chronic stroke patients. Methods: Thirty subjects with chronic stroke disease were divided into two groups: a trunk exercise group that used less-affected extremities (n=15) and a general trunk exercise group (n=15). All interventions were conducted 30 min a day, 6 times per week, for 3 weeks. Gait parameters were measured before and after the intervention using Zebris FDM-1.5. In addition, all subjects were evaluated using the Trunk Impairment Scale, the Berg Balance Scale, and the Functional Gait Assessment before and after the intervention. Results: Both groups showed improvements on all outcome measured pre- to post-intervention (p<0.05). The groups exhibited significant differences for TIS, BBS, FGA, gait speed, step length, and cadence at post-intervention (p<0.05). Conclusion: This study showed that trunk exercise using less-affected extremities has therapeutic benefits on gait and balance in individuals with chronic stroke disease.

• 농촌의학ㆍ지역보건
• /
• 제32권1호
• /
• pp.41-51
• /
• 2007

Objectives: The aim of this study was to evaluate the effects of exercise on the cardiovascular and musculoskeletal variables and quality of life in elderly women. Methods: The study subjects were 22 in experimental group and 21 in the control group, all of who were aged 65 years and over. The subjects in the experimental group were under an exercise program 3 times a week for one year. To assess the effects of exercise in the study group, blood pressure, heart rate, lipid profile, bony metabolism, grip strength, flexibility, reaction time, and quality of life were measured. Results: Exercise showed the significant differences between experimental and control groups on the variables of the diastolic blood pressure, HDL-cholesterol, urinary deoxypyridinoline, flexibility, and quality of life. Compared to before the exercise in the study group, the urinary DPD level and quality of life were significantly improved at 3 months, and diastolic blood pressure, serum HDL-cholesterol, and flexibility were significantly improved by 1 year. Conclusions: The study results underscore the efficacy of exercise and the need for regular exercise programs that are designed for older persons.

• 대한물리의학회지
• /
• 제13권3호
• /
• pp.141-150
• /
• 2018

PURPOSE: This study was conducted to understand the adaptive responses of different modes of physical exercises utilizing skeletal muscle and the comprehensive relevance of AMPK signaling that can be activated by physical exercise as a potential molecular target in human health problems such as neuromuscular disorders (NMDs). METHODS: Most of the contents in this review article are based on recent publications concerning the main topics of interest. The reference literatures cited were obtained by basic searches of overseas academic databases such as PubMed and ScienceDirect using EndNote X7.8. RESULTS: The phenotypic adaptive responses of skeletal muscle during endurance- and resistance-based exercise training (ET and RT respectively) appear to be distinct. To explain the adaptive responses in each single mode of exercises (ET, RT) along with combined exercise training (CT), AMPK signaling is proposed as an important molecular link among those differential modes of exercise and a promising molecular target of NMDs. CONCLUSION: Based on the available evidence, intracellular AMPK signaling activated by diverse stimuli including physical exercise can be a potential and promising therapeutic target for the prevention, amelioration or cure of various human health problems including NMDs and may also be beneficial for physical rehabilitation and emergency situations that may elicit acute metabolic stresses.

• The Korean Journal of Physiology and Pharmacology
• /
• 제19권3호
• /
• pp.191-196
• /
• 2015

Attenuated functional exercise capacity in elderly and diseased populations is a common problem, and stems primarily from physical inactivity. Decreased function and exercise capacity can be restored by maintaining muscular strength and mass, which are key factors in an independent and healthy life. Resistance exercise has been used to prevent muscle loss and improve muscular strength and mass. However, the intensities necessary for traditional resistance training to increase muscular strength and mass may be contraindicated for some at risk populations, such as diseased populations and the elderly. Therefore, an alternative exercise modality is required. Recently, blood flow restriction (BFR) with low intensity resistance exercise (LIRE) has been used for such special populations to improve their function and exercise capacity. Although BFR+LIRE has been intensively studied for a decade, a comprehensive review detailing the effects of BFR+LIRE on both skeletal muscle and vascular function is not available. Therefore, the purpose of this review is to discuss previous studies documenting the effects of BFR+LIRE on hormonal and transcriptional factors in muscle hypertrophy and vascular function, including changes in hemodynamics, and endothelial function.

• Physical Therapy Rehabilitation Science
• /
• 제1권1호
• /
• pp.40-48
• /
• 2012

Objective: The aim of this study was to compare sling exercise group to McKenzie exercise group in patients with chronic neck pain. Design: Two group pretest-posttest design. Methods: Twenty subjects who have chronic neck pain were randomly divided into sling exercise group (n=10) and McKenzie exercise (n=10). Sling exercise group (n=10) received sling exercise for 30 minutes per day, twice a week over a 4 week period. And the other group were exercised McKenzie exercise (n=8) for 30 minutes per day, twice a week over a 4 week period. Neck disability index (NDI), Visual analog scale (VAS), algometer, digital manual muscle tester (MMT) and cervical muscle strength and cervical range of motion (ROM) are closely measured to identify the effect of sling exercise and McKenzie exercise. Results: For NDI, VAS, algometer on both trapezius, both rotation of cervical muscle strength, both lateral flexion of cervical muscle strength, cervical extension of ROM and both lateral flexion of ROM were significantly increased after intervention in sling exercise group (p<0.05), For VAS, algometer on both trapezius, left (Lt.) rotation of cervical muscle strength, Lt. lateral flexion of cervical muscle strength, cervical flexion and extension of ROM and Lt. lateral flexion of ROM were significantly increased after than before intervention in McKenzie exercise group (p<0.05). Conclusions: These study outcomes clearly support the notion that sling and McKenzie exercise improved pain, Muscle strength and ROM of patients with chronic neck pain. These results suggest that sling and McKenzie exercise program is suitable for chronic neck pain.

• 농촌의학ㆍ지역보건
• /
• 제29권1호
• /
• pp.185-194
• /
• 2004

건강증진사업을 실시하고 있는 충청남도 1개 군의 보건소에서 내원하는 주민 중 신체적 운동을 통하여 자신의 건강을 증진시키고자 하는 동기가 있는 주민을 대상으로 보건소의 운동 프로그램 교육을 받은 교육군 142명과 교육을 받지 않은 비교육군 72명에서 대하여 2003년 4월부터 9월까지 건강상태(SF-36) 변화와 운동행태의 변화에 대해 조사한 결과 다음과 같은 결론을 얻었다. 운동 프로그램을 교육받은 군에서는 비교육군에 비해 높은 운동지식과 태도를 보였으며, 교육 후 비교육군에 비해 운동 횟수의 증가를 보였다. 교육군에서 비교육군보다 건강상태의 점수가 전반적으로 높아졌으나 통계적으로 유의하지는 않았다. 운동 실천군은 운동 비실천군에 비해 운동에 대한 지식과 태도가 높았고, 조사 기간동안 운동 횟수의 증가를 보였다. 이와 같이 운동 교육 프로그램은 보건 기관 방문자들의 지식과 태도 및 운동을 다소 향상시켰다. 비교적 단기간의 소규모 연구로서 운동 교육 프로그램에 의한 건강상태의 증진효과는 뚜렷하지 않았으나 향후 적절한 강도의 장기적 운동 교육 프로그램을 통한 연구가 이루어 진다면 보다 긍정적인 효과를 기대할 수 있을 것으로 사료된다.