• 동의생리병리학회지
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• 제19권6호
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• pp.1573-1579
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• 2005

This study was undertaken to define the effect of DaeSiHo-Tang extract on the hypertension in spontaneous hypertensive rat and norepinephrine-induced arterial contraction in rabbit. Systolic blood pressure and blood velocity were significantly attenuated by administration of DaeSiHo-Tang extract. but blood flow and renin-angiotensin-aldosterone system unaffected by DaeSiHo-Tang extract. The relaxation effect of DaeSiHo-Tang extract was dependent on the presence of endothelium, showing that DaeSiHo-Tang extract-induced relaxation was not observed in the strips without endothelium. The endothelium-dependent relaxation induced by DaeSiHo-Tang extract was decreased by the pretreatment of $N{\omega}$-nitro-L-arginine or methylene blue, but it was not observed in the strips pretreated with indomethacin or tetraethylammonium chloride. When $Ca^{2+}$ was applied, the strips which were contracted by norepinephrine in a $Ca^{2+}$-free solution, arterial contraction was increased. But pre-treatment of DaeSiHo-Tang extract inhibited contractile response to $Ca^{2+}$. These results indicate that antihypertensive effect of DaeSiHo-Tang extract is due to descend arterial resistance by the arterial relaxation through the formation of nitric oxide in the vascular endothelial cells.

• 동의생리병리학회지
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• 제19권6호
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• pp.1622-1628
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• 2005

This study was undertaken to define the effect of SoPung-Tang extract on hypertension in spontaneous hypertensive rat and norepinephrine- induced arterial contraction in rabbit. In order to investigate the effect of SoPung-Tang extract on contracted rabbit carotid arterial strips, transverse strips with intact or damaged endothelium were used for the experiment using organ bath. To analyze the mechanism of SoPung-Tang extract-induced relaxation, SoPung-Tang extract infused into contracted arterial strips induced by norepinephrine after treatment of indomethacin, Nu-nitro-L-arginine, methylene blue or tetraethylammonium chloride. Blood pressure was significantly decreased five days after administration of SoPung-Tang extract. SoPung-Tang extract relax arterial strip with endothelium contracted by norepinephrine, but in the strips without endothelium, SoPung-Tang extract- induced relaxation was significantly inhibited. SoPung-Tang relax arterial strip contracted by norepinephrine, but in the strips contracted by high $K^+$, SoPung-Tang extract-induced relaxation was significantly inhibited. The endothelium-dependent relaxation induced by SoPung-Tang extract was decreased by the pre-treatment of $N{\omega}$-nitro-L-arginine or methylene blue, but it was not observed in the strips pre-treated with indomethacin or tetraethylammonium chloride. When $Ca^{2+}$ was applied, the strips which were contracted by norepinephrine in a $Ca^{2+}$-free solution, arterial contraction was increased. But pre-treatment of SoPung-Tang extract inhibited contractile response to $Ca^{2+}$. We suggest that SoPung-Tang could be applied effectively for hypertension and may suppress influx of extra-cellular $Ca^{2+}$ through the formation of nitric oxide in the vascular endothelial cells.

• 동의생리병리학회지
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• 제19권6호
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• pp.1496-1503
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• 2005

This study aims to define the relationship between brain and heart through several literatures about oriental medicine and the conclusions are as follows. Heart in oriental medicine is called as Sinmyeongjishim(神明之心) which has a close connection with Mind, Consciousness, Emotion, and Physiological instinct of Drain in modern medicine. According to Oriental medicine, Brain stores Wonsin(元神) as Heart stores mind(神). Heart is where mind rests whereas Brain is where mind reveals. The external evidences that prove the relationship of Heart and Mind are as follows: First, with ears, eyes, mouth, and nose the subject of cognition is recognized as Sinmyeongjishim(神明之心). Second, Bulin(不仁), which means decreased movement power and sensibility of limbs, proves that Sinmyeongjishim(神明之心) is involved with movement power and sensibility of limbs. The physiological evidences that prove the relationship of Heart and Mind are as follows; First, Heart as the operation of Sinmyeongjishim(神明之心) manages language. Second, Heart is related with Tongue. Third, Heart is linked to Ears through the ear hole. Fourth, Heart is a store of Mind. Fifth, the five viscera control emotional and psychological activities. The pathological evidence of the relationship of Heart and Mind is that the symptoms of heart disease which are related to Sinmyeongjishim(神明之心) are also related to the functions of Brain. Though Brain has a close connection with Heart in oriental medicine, it is recognized that there are distinctive symptoms of disease of Brain and Hyeolyookjishim(血肉之心) respectively. The relationship of Heart and Brain has been researched in this study, even though there are not enough written materials about oriental medicine. But the fact that the majority of Heart operation is deeply connected with Brain activities cannot be denied. Therefore the research of Heart should be done as well as Brain in the clinical study of Brain.

• 동의생리병리학회지
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• 제28권6호
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• pp.577-584
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• 2014

The purpose of this study was to examine how the term Yin-Yang and Sasang categorized in the book "Huangdineijing". In order to investigate how the terms are used, we reviewed the text including the terms expressed in the manner of [(Yin/Yang) within (Yin/Yang)] and [Sasang]. We found three forms of expressions; [(Yin/Yang) within (Yin/Yang)], [Sasang], [(Sasang) within (Yin/Yang)]. Two paragraphs of [(Yin/Yang) within (Yin/Yang)] was found in one chapter, two paragraphs of [(Sasang)] was found in two chapters, and three paragraphs of [(Sasang) within (Yin/Yang)] was found in three chapters. We found five types of relation between [(Yin/Yang) within (Yin/Yang)], [Sasang], and five phases in "Huangdi neijing" as follows; (1) Yang within Yin, lesser Yang, and wood (2) Yang within Yang, greater Yang, and fire (3) ( ), ( ), and extreme Yin (4) Yin within Yang, lesser Yin, and metal, and (5) Yin within Yin, greater Yin, and water. And, as for the [(Yin/Yang) within (Yin/Yang)] and [(Sasang) within (Yin/Yang)], the classification criteria for Yin-Yang were brightness, abdomen/back or lumbar. The order of Sasang with the description form of [Sasang] or [(Sasang) within (Yin/Yang)] in "Siqi Tiaoshen Dalun" and "Liu Jie ZangXiang Theory" was lesser Yang, greater Yang, greater Yin, and lesser Yin, which is based on the meridian system or a plant-shaped change order. We discussed the results and its implication for the analysis of medical classics with the consideration of previous studies on Yin-Yang theories in "Huangdi neijing".

• Korean Journal of Acupuncture
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• 제22권4호
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• pp.129-147
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• 2005

Objectives and methods : This research aims to study about Gimunchimbeop(奇門鍼法) from original text of ${\ulcorner}$Singyeol(神訣) and Bosingyeol(保身訣)${\lrcorner}$. I could know is contents about Gimunchim-beop(奇門鍼法) through result that interprets original text of ${\ulcorner}$Singyeol(神訣) and Bosingyeol(保身訣)${\lrcorner}$ with Hyeonto(懇吐) and analyzes, and Gimunchimbeop(奇門鍼法)'s contents are as following. Results and Conrlusions : ${\ulcorner}$Singyeol(神訣) and Bosingyeol(保身訣)${\lrcorner}$ is seen uses Honggukpoyeol-beop(洪局布列法)'s Saenggipalgwae(生氣八卦) among Gimunpogukbeop(奇門鐵法), and Yearngukpoyeol-beop(姻局布列法) that do Sigapoguk(時家布局) by putting first. It Introduced method that depends to Saenggipalgwae(生氣八卦) in Sigapoguk(時家布局)'s occasion and selects, and doctors depend to Bideungpalbeop(飛謄八法)'s Palmaekpalhyeolbaegugungpal-gwaedo(八販八穴配九嘗八卦圖) deciding Bongwae(本卦) via a day to look at patient and selects Juhyeol(主穴), Assign Saenggipalgwae(生氣八卦) laying stress on Bongwae(本卦) and makes Bojohyeol(補助穴) equivalent to Saenggi(生氣), good luck(福德) and Cheoneui(天宜). but, this need study more should use distinguishing how because was not proved. Wonpando(圓板圖) and Babdo(方圖) from Eumyangdun(陰賜遁)'s from 1 Guk(局) to 9 Guk(局) are thing for Yeamgukpoyeolbeop(姻局布列法). But it is few references about there decides Hyeolwi(穴位) that use even if arrange actually. Through ${\ulcorner}$Singyeol(神訣) and Bosingyeol(保身訣)${\lrcorner}$, I could know truth that took advantage of strange news to acupuncture methods(鐵法) but specific practical use method does not remain. Need to establish body of theory in reply in hereafter therefore and prove the effect through presence at a sickbed practical use.

• 대한한의학회지
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• 제26권1호
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• pp.71-75
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• 2005

There are wide variations in the definition and functions of tri-jiao among investigators in the area of Chinese medicine. Given a wide spectrum of views, it is difficult to identify uniform opinions about the definition and functions of tri-jiao. This paper is intended to clarify the meaning of the tri-jiao, which was presented as 'it builds a waterway and serves as the passage for the flow of Shuidao' in ${\ulcorner}\;SuWen\;\cdot\;Linglanbidianlun\;{\lrcorner}$ a classic text of traditional Chinese medicine. Investigators have been divided in their opinions in interpreting this reference; some claim that tri-jiao regulates fluid metabolism in the entire body while others assert that the role of tri-jiao is limited to lower-jiao that controls urination function. However, this does not appear convincing given the description in other texts of ${\ulcorner}\;SuWen\;\cdot\;Linglanbidianlun\;{\lrcorner}$, in which functions of 12 organs were explained in a summarized manner. The assumption that the role of tri-jiao is closely linked with lower-jiao seems to have deviated from the meaning of the original texts. Besides, fluid metabolism involves the entire body, and any pathological changes caused by disorders of fluid metabolism can affect any part of the body, not only the lower area of the body cavity. The phrase, 'passage for the flow of Shuidao,' expressed in the texts of ${\ulcorner}\;SuWen\;\cdot\;Linglanbidianlun\;{\lrcorner}$ is likely to mean that body fluid is also distributed and transported to the whole body along with primordial-Qi via tri-jiao. The phrase, 'passage for the flow of Shuidao' means that tri-jiao is involved in regulating body fluid metabolism and that it plays an important role in fluid distribution.

• Journal of Acupuncture Research
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• 제25권5호
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• pp.77-87
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• 2008

Objectives : We would like to look into the understanding and errors of the changes in the 'Suhyeoljuchijeung' of acupuncture and moxibustion through the documentary study of Gomu's(高武) $\ll$Chimgujeolyochiyeong$\gg$ today. Methods : Based on Hwangyongsang(黃龍祥)'s study, the author of the $\ll$Chimgujeolyochiyeong$\gg$, date it was written, the number of volumes and edition, basic contents, basic constitution, referenced books and characteristics, influence on posterity, the documentary research results will be arranged. Results & Conclusions : 1. $\ll$Chimgujeolyochiyung$\gg$ was first printed in the 16th year of the Gajung(嘉靖) era during the Myeong(明) dynasty(1537). It has a total of 7 volumes and is divided into 3 books(帙). The first book is three volumes of $\ll$Chimgujeolyo(鍼灸節要)$\gg$, and the second and third books are 4 volumes of $\ll$Chimguchiyung(鍼灸聚英)$\gg$. 2. The main content of this book is 'Suhyeoljuchijeung' of volume 1, and was written based mainly on Wangjipjung(王執中)'s $\ll$Chimgujasenggyeong(鍼灸資生經)$\gg$. also it was the first to systematically arrange the indications of acupuncture points after $\ll$Myeongdanggyeong(明堂經)$\gg$. 3. The author, Gomu was influenced by the 'literary restoration movement(文學複古運動)' of the time, resulting in the 'Jongyeongsunggo(尊經崇古)' ideology being reflected in $\ll$Chimgujeolyochiyung$\gg$.

• Korean Journal of Acupuncture
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• 제25권4호
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• pp.1-15
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• 2008

Objectives : This study is designed to investigate the association between Samcho-gyeong(TE) and the lower branch of Meridian system. Methods : The base of the study was established by searching for the historic conception of Samcho. Thereafter the meaning of lower correlation was considered and the property of lower part of Samcho Meridian system studied. Results : Samcho is a kind of Yug-Bu(Six hollow viscera, 六腑). It is a functional internal organ, which has been continuously controversial in history. It covers wide range of the internal organs and plays various kinds of roles. Samcho and Simpo lack in interrelation of obverse and reverse. The conception of Sanghap(Upper correlation, 上合) in Naegyeong supplements the deficiency. To establish the conception of Sanghap between Yug-Bu and Hand meridians, there should be established the conception of Hahap(Lower correlation, 下合) between Yug-Bu and foot meridians for treating lower parts. The existence of Hahaphyeol(Lower confluent points, 下合穴) reveals that there were a lot of limits in treating JungHa-cho(Middle and Lower energizers, 中下焦) diseases only with the acupoints of the Hand meridians. Jogsamcho(Triple energizer of foot, 足三焦) meridian written in Taeso(太素), corresponds to the lower leg, and it is believed that it engages in treating diseases in the trunk of the body and Hacho(Lower energizer, 下焦). Conclusions : Therefore, it is believed that the lower part of meridian of Samcho can deal with the symptoms of lower back pain, leg pain, bladder disease, and so on. This study is meaningful in that it expands the range of treatment in acupoints of the regular meridians.

• 대한예방한의학회지
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• 제14권1호
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• pp.59-76
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• 2010

Background : The system for collecting and managing the terminologies of Korean oriental medicine is essential to facilitate researches of developing intelligent information architecture based on ontology. Objectives : The purpose of this paper is to develop system for collecting and managing system for terminologies of Korean oriental medicine. Methods : First we defined roles of users used in this system, and define the system workflow based on them. Then we developed web-based collecting and managing system in which multiuser can work simultaneously, and it is compose of relational database system. Results : The terminologies of Korean Oriental Medicine can be efficiently collected, purified, inspected, and utilized by using proposed system. Conclusions : The system, proposed in this paper, can be used the whole field of oriental medicines for basic technology and has great contributions to make intelligent information architecture of oriental medicine based on ontology concept.

• 동의생리병리학회지
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• 제33권5호
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• pp.249-254
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• 2019

This study is aimed to refute against medical opponent's claim that Korean medicine does not conform to the conditions of science. Analyses and refutations against a journal treatise and a Facebook column formally written for a logical criticism and attack were conducted. As an example of the logic of the knowledge production process in Chinese medicine, 8 principle theory was exemplified in the Han danasty Classics "Neijing" and "Shanghanlun" at first. The knowledge was continuously revised and accumulated historically and then completed through Ming、Cheng period. The differential diagnosis and treatment theory is a logical process of forming knowledge through the process of abduction, deduction and induction begun from "Shanghanlun" succeeded to nowadays and it is essentially equaled with the process of experimental inference by Claude Bernard. Examples of normal science status based on Kuhn's scientific standards include the theory of 8 principle, differntial diagnosis of viscera and bowel, 3 yang and 3 yin diseases of "Shanghanlun" and warm disease theory. Examples of science lost or get its normal status by refutation following Popper's standards were cold damage theory and warm disease theory respectively. This allowed Chinese medicine to follow the general principles of science that form scientific knowledge and to correspond with the demarcation standards and concepts of science. However, as one of the conditions for becoming a science, Chinese medicine is partially lacking in terms of the interpretation of text language or the accordance with modern knowledge. Therefore methods are required to supplement this lack through multi-faceted research such as literature-based, theoretical and clinical studies.