• Journal of Biomedical Engineering Research
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• v.24 no.4
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• pp.363-367
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• 2003

Contact area and pressure are important factors which directly influence a life of knee implants. Since implant's mechanical functions should be experimentally evaluated for clinical use, many studies using a knee simulator and a pressure sensor system have been conducted. However it has not been reported that the contact pressure's distribution of a knee implant motion was estimated in real-time during a gate cycle. Therefore. the objective of this study was to analyze the contact pressure distribution for the motion of a joint using the knee simulator and I-scan sensor system. For this purpose, we developed a force-controlled dynamic knee simulator to evaluate the mechanical performance of artificial knee joint. This simulator includes a function of a soft tissue and has a 4-degree-of-freedom to represent an axial compressive load and a flexion angle. As axial compressive force and a flexion angle of the femoral component can be controlled by PC program. The pressure is also measured from I-scan system and simulator to visualize the pressure distribution on the joint contact surfaces under loading condition during walking cycle. The compressive loading curve was the major cause for the contact pressure distribution and its center move in a cycle as to a flexion angie. In conclusion, this system can be used to evaluate to the geometric interaction of femoral and tibial design due to a measured mechanical function such as a contact pressure, contact area and a motion of a loading center.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.10a
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• pp.834-837
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• 2015

In this paper, we designed the FPGA hardware-based real-time ECG simulator, which generates an analog ECG signal within the range of 0 to 5 volts and described function. The ECG signal generated by the simulator can be applied to laboratory tests, the medical device, and the calibration study in various ways. ECG signals generated by simulator are obtained with conventional 24bit quantization to generate the signal data, and they are sampled and quantized to 1kHz of the 8-bit resolution when used as actual data. The proposed simulator is implemented using xilix Spartan-3 and data are transmitted through an RS-232 between the PC and the FPGA simulator. The transmitted data are stored in the memory and the stored data are printed out with the analog ECG signal through DAC (0808). It can also control the heart rate (HR) via the two buttons level UP-DOWN. We used existing ECG input rating for the evaluation of the designed system and evaluated differential circuit for obtaining QRS waveform and the output signal. We finally could obtained proper the result.

• Biomedical Engineering Letters
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• v.8 no.4
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• pp.383-392
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• 2018

For prompt gamma ray imaging for biomedical applications and environmental radiation monitoring, we propose herein a multiple-scattering Compton camera (MSCC). MSCC consists of three or more semiconductor layers with good energy resolution, and has potential for simultaneous detection and differentiation of multiple radio-isotopes based on the measured energies, as well as three-dimensional (3D) imaging of the radio-isotope distribution. In this study, we developed an analytic simulator and a 3D image generator for a MSCC, including the physical models of the radiation source emission and detection processes that can be utilized for geometry and performance prediction prior to the construction of a real system. The analytic simulator for a MSCC records coincidence detections of successive interactions in multiple detector layers. In the successive interaction processes, the emission direction of the incident gamma ray, the scattering angle, and the changed traveling path after the Compton scattering interaction in each detector, were determined by a conical surface uniform random number generator (RNG), and by a Klein-Nishina RNG. The 3D image generator has two functions: the recovery of the initial source energy spectrum and the 3D spatial distribution of the source. We evaluated the analytic simulator and image generator with two different energetic point radiation sources (Cs-137 and Co-60) and with an MSCC comprising three detector layers. The recovered initial energies of the incident radiations were well differentiated from the generated MSCC events. Correspondingly, we could obtain a multi-tracer image that combined the two differentiated images. The developed analytic simulator in this study emulated the randomness of the detection process of a multiple-scattering Compton camera, including the inherent degradation factors of the detectors, such as the limited spatial and energy resolutions. The Doppler-broadening effect owing to the momentum distribution of electrons in Compton scattering was not considered in the detection process because most interested isotopes for biomedical and environmental applications have high energies that are less sensitive to Doppler broadening. The analytic simulator and image generator for MSCC can be utilized to determine the optimal geometrical parameters, such as the distances between detectors and detector size, thus affecting the imaging performance of the Compton camera prior to the development of a real system.

• Journal of Biomedical Engineering Research
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• v.45 no.1
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• pp.49-55
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• 2024

Accurate measurement of blood pressure is essential for classifying an individual's disease, identifying blood pressure-related risks, and managing health. Due to the environmental and health hazards of mercury sphygmomanometers, automatic sphygmomanometers using the oscillometric method are widely used in hospitals as well as in general homes, and have established themselves as a practical standard sphygmomanometer. In this study, we developed a blood pressure simulator using an actuator that provides simulated pressure to an automatic blood pressure cuff. The developed blood pressure simulator adopts an arm-shaped cylindrical shape similar to the situation in which a person measures blood pressure with an automatic blood pressure monitor, and implements a method of transmitting pressure to the cuff using a pressure plate. Accuracy was evaluated through the mean and standard deviation of the difference with the commercialized blood pressure simulator BP PUMP 2, and reproducibility was confirmed using two automatic blood pressure monitors. The developed blood pressure simulator enables automatic blood pressure monitoring in a simple manner and also meets the evaluation standards for accuracy and reproducibility. In the future, as a standardized blood pressure simulator, it is expected to be of great help in evaluating and verifying the performance of automatic blood pressure monitors by supplementing precise hardware and software and building a blood pressure database.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.852-856
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• 2005

This paper proposes a new design of the ECG simulator with high resolution by using small amount of memories based on discrete least square estimation equations instead of reading the stored data inside the look-up table. The experimental results have shown that the ECG simulator using discrete least square estimation equations can display the bipolar limb leads ECG signals with low PRD (percent root-mean-square difference) while taking the less amount of memories than the previous method which used the look-up table to store ECG data for ECG simulation.

• International Journal of Fuzzy Logic and Intelligent Systems
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• v.1 no.1
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• pp.104-112
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• 2001

Simply, Nonlinear dynamics theory means the complicated and noise-like phenomena originated form nonlinearity involved in deterministic dynamical system. An almost all the natural signals have nonlinear property. However, there exist few analysis software tool or package for a research and development of applications. We develop nonlinear time series analysis simulator is to provide a common and useful tool for this purpose and to promote research and development of nonlinear dynamics theory. This simulator is consists of the following four modules such as generation module, preprocessing module, analysis module and ICA module. In this paper, we applied to Electroencephalograph (EEG), as it turned out, our simulator is able to analyze nonlinear time series. Besides, we could get the useful results using the various parameters. These results are used to diagnostic the brain diseases.

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.76-77
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• 1998

In this paper, the authors have implemented a blood flow simulator and a blood flowmeter probe using self-mixing effect of the laser diode. The purpose of the blood simulator is to simulate microvascular blood flow in tissue. It consists of melinex film (thickness = $125{\mu}m$) which has similar optical characteristics to epidermis and porous polyethylene filter (Vyon, porosity 35%, mean pore size $50{\mu}m$, thickness=1 mm) which has similar optical characteristics to dermis. The blood flowmeter probe consists of laser diode(5 mW, 780 nm wavelength), CD lens(focal lenght 12 mm), current-to-voltage converter, highpass filter, and preamplifier. It doesn't need optical fiber, therefore, implementation of the probe is simpler than conventional probe using optical fiber.

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.135-136
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• 1998

The purpose of this study is to develope a validation method for driving simulator. Physiological responses such as EOG, ECG, and driver's behaviour were measured by using actual vehicles. The characteristics of the recognition of the acceleration by the human are investigated. These results showed that physiological responses was changed by the driving environment. Subject recognized that he drove more than real distance and turning angle.

• Journal of Biomedical Engineering Research
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• v.18 no.1
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• pp.9-16
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• 1997

We develop an automatic imaging matching technique for combining portal image and simulator image for improvements in localization of treatment in radiation therapy. Fusion of images from two imaging modalities is treated as follows. We archive images thxough a frame-yabber. The simulator and portal images are edge detected and enhanced with interpolated adaptive histouam equalization and combined using geometrical parameters relating the coordinates of two image data sets which are calculated using Fourier descriptors. We don't use any kind of imaging markers for patient's convenience. clinical use of this image matching technique for treatment planning will result in improvements in localization of treatment volumes and critical structures. These improvements will allow greater sparing of normal tissues and more precise delivery of energy to the desired irradiation volume.

• Journal of the Institute of Electronics and Information Engineers
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• v.49 no.10
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• pp.187-193
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• 2012

Digital X-ray image detector has been applied for medical and industrial fields. Photoconductors have been used to convert the X-ray energy to electrical signal on the direct digital X-ray image detector and amorphous selenium (a-Se) has been used as a photoconductor, normally. In this work, we use 2-dimensional device (2-D) simulator to study about physical phenomena in the a-Se, when we irradiate electromagnetic radiation (${\lambda}=486nm$) on the a-Se surface. We evaluate the electron-hole generation rate, electron-hole recombination rate, and electron/hole distribution in the a-Se using 2-D simulator. This simulator divides the device into triangle and calculates using interpolation method. This simulation method has been proposed for the first time and we expect that it will be applied for the development of digital X-ray image detector.