• The Journal of the Society of Korean Medicine Diagnostics
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• v.10 no.2
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• pp.67-78
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• 2006

Objectives : To review the method, validity and reliability of Impedance Cardiography and to study its oriental medical application. Method : The papers reviewed in this study were searched through internet search engines such as Springer, Science Direct, and China National Knowledge Infrastructure. Conclusion : In this study, the methodological limitations, validity and reliability of impedance cardiography were examined. Impedance Cardiography is recognized as a highly accurate non-invasive tool to assess hemodynamic parameters. The ability of impedance cardiography to assess hemodynamic parameters in non-invasive way is very suitable for researches on the effect of oriental medical therapeutics or the validation of oriental medical diagnostic.

• Journal of Korean Medical classics
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• v.21 no.4
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• pp.133-159
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• 2008

Every field of studies form its theory through its universal method and own method based on respective views with its own culture and contributes to academic advancement with appropriate research methodology within theory. Therefore, If methology of oriental medicine is not include universal method and particularity method in research methology, it will not obtain scientific character and lose its logic. The methology of oriental medicine is classified by two approaches, universal methology of natural science which inspect the effect through experimentation on the fact, and particularity methology of human science which understand the effect through translation on the value(politics, economics, society, philosophy, history and culture). In this paper, the methodology of oriental medicine contains duality including both universality and particularity.

• Journal of Computing Science and Engineering
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• v.11 no.4
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• pp.109-110
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• 2017

• Journal of the Korean Society for information Management
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• v.30 no.2
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• pp.207-225
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• 2013

Due to the development of science and technology, the convergence of various disciplines has been fostered. Accordingly, interdisciplinary studies have increasingly been expanded by integrating knowledge and methodology from different disciplines. The primary focus of biblimetric methods is on investigating the intellectual structure a field, and analysis of the characterization of interdisciplinary studies is overlooked. In this study, we aim to identify the intellectual structure of the field of medical informatics through author co-citation analysis and co-word analysis by the representative journal "IEEE ENG MED BIOL." In addition, we examine authors and MeSH Terms of top three representative journals for further analysis of the field. We examine the intellectual structure of the medical informatics field by author and word clusters to identify the network structure of medical informatics disciplines.

• Proceedings of the Korea Information Processing Society Conference
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• 2004.05a
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• pp.1083-1086
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• 2004

Switched Network는 Shared Network 에 비해서 스니핑에 안전하다. 하지만 비교우위일뿐 절대적으로 스니핑에 안전한 것은 아니다. 이미 Switched Network 상에서 스니핑을 할 수 있는 공격툴들이 많이 소개되어 있다. 본 논문에서는 Switched Network 상에서 ARP(Address Resolution Protocol) 스푸핑을 통한 ARP 캐시 오염을 통하여 스니핑이 가능한 시나리오를 기술한다. 이러한 시나리오를 탐지하기 위한 기존의 방법은 DHCP와 같은 동적인 환경이 포함된 경우 False Positive 를 자주 발생시키기 때문에 문제가 된다. 여기에서는 이러한 False Positive를 줄인 탐지 방법을 제시하고자 한다.

• 대한예방의학회:학술대회논문집
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• 2000.10a
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• pp.185-186
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• 2000

• Genomics & Informatics
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• v.1 no.2
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• pp.87-93
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• 2003

DNA microarray is currently the most prominent tool for investigating large-scale gene expression data. Different algorithms for measuring gene expression levels from scanned images of microarray experiments may significantly impact the following steps of functional genomic analyses. $Affymetrix^{(R)}$ recently introduced high-density microarrays and new statistical algorithms in Microarray Suit (MAS) version 5.0$^{(R)}$. Very high correlations (0.92 - 0.97) between the new algorithms and the old algorithms (MAS 4.0) across several species and conditions were reported. We found that the column-wise array correlations had a tendency to be much higher than the row-wise gene correlations, which may be much more meaningful in the following higher-order data analyses including clustering and pattern analyses. In this paper, not only the detailed comparison of the two sets of algorithms is illustrated, but the impact of the introducing new algorithms on the further clustering analysis of microarray data and of possible pitfalls in mixing the old and the new algorithms were also described.

• The Journal of Korean Medicine
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• v.33 no.4
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• pp.60-68
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• 2012

Objectives: By grasping trends in research, technology, and general characteristics of learning support tools, this study was conducted to present a model for research on Korean Medicine (KM) to make use of information technology to support teaching and learning. The purpose is to improve the future clinical competence of medical personnel, which is directly linked to national health. Methods: With papers and patents published up to 2011 as the objects, 438 papers were extracted from "Web of Science" and 313 patents were extracted from the WIPS database (DB). Descriptive analysis and network analysis were conducted on the annual developments, academic journals, and research fields of the papers, patents searched were subjected to quantitative analysis per application year, nation, and technology, and an activity index (AI) was calculated. Results: First, research on medical learning support tools has continued to increase and is active in the fields of computer engineering, education research, and surgery. Second, the largest number of patent applications on medical learning support tools were made in the United States, South Korea, and Japan in this order, and the securement of remediation technology-centered patents, rather than basic/essential patents, seemed possible. Third, when the results of the analysis of research trends were comprehensively analyzed, international research on e-PBL- and medical simulation-centered medical learning support tools was seen to expand continuously to improve the clinical competence of medical personnel, which is directly linked to national health. Conclusions: The KM learning support tool model proposed in the present study is expected to be applicable to computer-based tests at KM schools and to be able to replace certain functions of national KM doctor license examinations once its problem DB, e-PBL, and TKM simulator have been constructed. This learning support tool will undergo a standardization process in the future.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.6
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• pp.834-841
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• 2012

We in this paper propose a mobile application for supporting medical treatment based on Korean medicine ontology. It has three processes for treating patients. First, after a pattern is decided for patient' symptoms, a formula for the pattern is selected and medicinal materials constituting the formula is added or removed. Second, formulas are searched and prescribed for patient's symptoms without the process of the pattern decision. Third, after medicinal materials are searched for patient's symptoms, formulas consisting of the medicinal materials are prescribed. Our application aims to help korean medicine doctors treat patients through providing decision supporting functions such as the recommendation of symptoms of diseases accompanying patient's symptom. Doctors generally diagnosis patients according to their experiences and knowledges. Nevertheless, our application can help them, providing diverse forms of information that they may miss in the medical treatment.

• Genomics & Informatics
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• v.12 no.4
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• pp.187-194
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• 2014

Metabolic syndrome (METS) is a disorder of energy utilization and storage and increases the risk of developing cardiovascular disease and diabetes. To identify the genetic risk factors of METS, we carried out a genome-wide association study (GWAS) for 2,657 cases and 5,917 controls in Korean populations. As a result, we could identify 2 single nucleotide polymorphisms (SNPs) with genome-wide significance level p-values (< $5{\times}10^{-8}$), 8 SNPs with genome-wide suggestive p-values ($5{\times}10^{-8}{\leq}$ p < $1{\times}10^{-5}$), and 2 SNPs of more functional variants with borderline p-values ($5{\times}10^{-5}{\leq}$ p < $1{\times}10^{-4}$). On the other hand, the multiple correction criteria of conventional GWASs exclude false-positive loci, but simultaneously, they discard many true-positive loci. To reconsider the discarded true-positive loci, we attempted to include the functional variants (nonsynonymous SNPs [nsSNPs] and expression quantitative trait loci [eQTL]) among the top 5,000 SNPs based on the proportion of phenotypic variance explained by genotypic variance. In total, 159 eQTLs and 18 nsSNPs were presented in the top 5,000 SNPs. Although they should be replicated in other independent populations, 6 eQTLs and 2 nsSNP loci were located in the molecular pathways of LPL, APOA5, and CHRM2, which were the significant or suggestive loci in the METS GWAS. Conclusively, our approach using the conventional GWAS, reconsidering functional variants and pathway-based interpretation, suggests a useful method to understand the GWAS results of complex traits and can be expanded in other genomewide association studies.