• Journal of Preventive Medicine and Public Health
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• v.40 no.2
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• pp.122-129
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• 2007

During the last decade, genomic cohort study has been developed in many countries by linking health data and genetic data in stored samples. Genomic cohort study is expected to find key genetic components that contribute to common diseases, thereby promising great advance in genome medicine. While many countries endeavor to build biobank systems, biobank-based genome research has raised important ethical concerns including genetic privacy, confidentiality, discrimination, and informed consent. Informed consent for biobank poses an important question: whether true informed consent is possible in population-based genomic cohort research where the nature of future studies is unforeseeable when consent is obtained. Due to the sensitive character of genetic information, protecting privacy and keeping confidentiality become important topics. To minimize ethical problems and achieve scientific goals to its maximum degree, each country strives to build population-based genomic cohort research project, by organizing public consultation, trying public and expert consensus in research, and providing safeguards to protect privacy and confidentiality.

• Journal of Korean Medical classics
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• v.28 no.1
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• pp.71-95
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• 2015

Objectives : I'd like to introduce a Korean medical scientist, Lee Gyoojoon (李圭晙, 1855-1923)'s achievements about Huangdi's Internal Classic (黃帝內經, HIC) to examine the Section of Viscera and Bowels to inspect the Medical Classics (稽經藏府篇, SVBIM) of the Double grinded Medical Mirror (醫鑑重磨, DMM), which is a medical book published in 1922, his last studies. And I'd like to describe its meaning of medical history. Methods : For this, I compared the DMM with two primary texts, the representative medical books of Joseon dynasty, Treasured Mirror of Eastern Medicine (東醫寶鑑, TMEM) and Lee's former research result of HIC, Major Essentials of Huangdi's Internal Classic Plain Question (黃帝內經素問大要, MEHIC), in the aspects of the original text, annotation, editing, attached theses, and so on. Results : Lee Gyoojoon criticized the TMEM in two aspects. First, it was unfocused and miscellaneous, second, it intended to help Yin Qi (陰氣) and reduce Yang Qi (陽氣) so that it regards a prime mover, Yang Qi, as an enemy. In order to solve these problems he deleted miscellaneous articles and sort out the points to accord with the HIC. As a result, he had written the Section of SVBIM of the DMM in the form of revising the subtitles or refuting the contents of TMEM and quoted the partial texts of MEHIC to be written by the view of Supporting Yang Qi (扶陽). Conclusions : Lee Gyoojoon proposed the Supporting Yang Qi medicine to preserve the Heart fire (心火) based on his lifelong Neo-Confucianism (性理學) study. The Section of SVBIM of the DMM showed how to apply his medical theory, which is achieved by the study of the medical classic HIC to real clinical medicine through a medium of the TMEM. In addition, it could explain concretely how the Confucianists studied the medicine and how Confucianism can impact to the development of medical theory.

• Clinical and Experimental Vaccine Research
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• v.12 no.2
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• pp.87-96
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• 2023

The fast development of vaccines against the novel coronavirus disease is among the most critical steps taken to control this potentially fatal viral disease. Like other vaccines, the coronavirus disease 2019 (COVID-19) vaccines can also cause unwanted reactions. Erythema multiforme (EM) is among the oral mucocutaneous side effects of COVID-19 vaccines. This study aimed to comprehensively review the reported cases of EM since the global onset of COVID-19 vaccination. Data from 31 relevant studies regarding the type and dose of COVID-19 vaccines administered, time of initiation of symptoms, age, and gender of patients, site of involvement, patients' medical history, and treatment options were extracted. In total, 90 patients were identified with EM as a side effect of COVID-19 vaccination across studies. EM had the highest frequency after receiving the first dose of mRNA vaccines in older individuals. The first symptoms of EM appeared in less than 3 days in 45% and after 3 days in 55% of patients. EM is not a common side effect of COVID-19 vaccination, and fear of its occurrence should not impede vaccination.

• Korean Journal of Oriental Medicine
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• v.17 no.3
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• pp.9-15
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• 2011

The Qiantang Medical School(錢塘醫派) formed on the basis of the education provided by L$\ddot{u}$shantang(侶山堂) in the specific area of Hangzhou(杭州) displays clear differences from other medical schools in that it combined medicine with educational and research activities. The Qiantang Medical School(錢塘醫派) played an important part in the history of the traditional Chinese medicine via providing the education through Confucian academies and the researches conducted to find appropriate treatment methods based on the climate and natural environment of the southern part of China. The tradition of joint researches on the classical works of Chinese medicine is equally important in terms of the traditional Chinese medicine.

• Journal of Korean Medical classics
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• v.37 no.2
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• pp.31-48
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• 2024

Objectives : The purpose of this paper is to find the corresponding pathological situation of the Renmai(任脈), Dumai(督脈), and Chongmai(衝脈) at the Cun(寸), Guan(關), Chi(尺) pulse positions using the Qikoujiudaomai diagnostic method in order to find the pathological pattern of the Eight Extra Meridians. The pulse positions are divided into nine parts, using a three dimensional surface-middle-bottom concept. Methods : Relevant contents in classical texts such as the Maijing, Qijingbamaikao, Zabingyuanliuxizhu, Maiyijianmo were examined, along with previous studies on the topic. The findings were that the Renmai, Dumai, Chongmai examination of the Qikoujiudaomai manifested as floating, tight, firm patterns in the Cun, Guan, Chi positions. Results & Conclusions : n terms of the Renmai, the converging and fast Qi manifested in the three positions as a tight pattern; in the Dumai, the extended and scattering Qi manifested in the three positions as a floating pattern; in the Chongmai, the excessive, solid and full Qi manifested in the three positions as a firm pattern. Once the pathological qi overflows in the 12 meridians, disease happens in the Eight Extra Meridians. As such, disease in the Renmai, Dumai, Chongmai were connected to the main meridians as three branches from one root. Through this study, it could be concluded that diagnosis and acupuncture treatment through the Qikoujiudaomai method is possible.

• Clinical and Experimental Pediatrics
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• v.55 no.8
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• pp.259-264
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• 2012

Wheezing is one of the most frequent complaints that lead to the use of medical resources in younger children. Generally, wheezing is caused by bronchiolitis and resolves spontaneously without recurrence, but sometimes, wheezing can progress into asthma. Early data on the natural history of childhood wheezing was mostly obtained from retrospective reviews of medical records or from questionnaires, which made it difficult to exclude biases. Now that many cohort studies are available, reviewing the results of birth cohort studies makes it possible to understand the natural course of early childhood wheezing and the risk factors for asthma. In this study, we have reviewed the various phenotypes of early childhood wheezing and their natural courses to help select the most appropriate management modalities for the different types of early childhood wheezing.

• Journal of Korean Medical classics
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• v.26 no.1
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• pp.85-98
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• 2013

Objectives : Final assessment of realized on forecasting studies of the literature sector on traditional Korean medicine (2000-2010) revealed results as follows. Methods : We investigated the related peer-reviewed papers and research project reports through Oriental Medicine Advanced Searching Integrated System(OASIS) of Korea Institute of Oriental Medicine(KIOM) and several publishers. Results : Of total five projects, two were realized and three were partially done. The projects 'It wil be standardized by establishing the concept of traditional Korean medical terms' and 'CDs containing traditional medicine books from China, Japan and Korea wiil be released' were decided to be realized. In addition to those, the projects 'Systematic database will be build up for TKM books', 'translation and annotation versions on TKM old books will be completed', and 'A wide range of literature related to traditional medicine of each Asian countries' were concluded to be partially realized. Five projects on predicting TKM in the year 2006-2007 analyzed in 1996 were evaluated as realized or partially realized. Likewise, the five predictions should be reviewed whether it will be necessary in the future after assessment on their realization. Conclusion : Furthermore, it should be studies if the new projects are needed for the future in addition to the existing challenges.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5427-5432
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• 2015

Background: Oral cancer stands among the 10 top causes of cancer death in the world. Considering the role of epidemiologic information on planning and effective interventions, the present study aimed to investigate the epidemiology of oral cancer in Iran. Materials and Methods: The required information for this systematic review study was obtained from PubMed, Google Scholar, CINAHL,SID, Medlib, Magiran and Iranmedex databases, using key words "cancer", "oral cancer", "squamous cell carcinoma", "oral cavity carcinoma" and their Persian equivalents in combination with keywords of epidemiology, prevalence, etiology, frequency, and Iran from 1990 to 2014. From 1,065 related studies found, finally 25 were included to the study. Results: The mean age of 8,248 patients in 25 studies was $54.0{\pm}15.1years$. The male/female ratio for oral cancer was 1.91. Tongue with average percentage of 29.9 was the most involved site. Regarding microscopic grade, 65.7% of cases were grade 1. SCCs, accounting for an average of 70.0%, was the most common among all types of oral cancer. In the majority of studies, smoking including cigarette, hookah, and tobacco consumption was found to be a risk factor. Conclusions: The epidemiological pattern of oral cancer in Iran is somewhat similar to that of other countries. Yet the information on hand in this field is limited and considering the role of epidemiological data we suggest conducting more accurate studies to catch data that is required for effective programs and interventions.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.1
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• pp.89-105
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• 2013

Objectives : The aim of this study is to analyze the domestic research trend focusing on well-being studies in medicine. Through this study, the researchers attempt to explore the research trends of the well-being in Traditional Korean Medicine. Methods : Well-being as a key word was searched on representative domestic databases of articles and the researchers collected the articles of medical journals published from 1980 to 2012. Finally 416 articles of well-being were selected. Results : Among the fields of medicine, well-being studies have been mainly proceeded by nursing science, preventive medicine and psychiatry. Well-being studies that mainly analyzed the variables associated wih quality of life and well-being to cancer patients, workers and elderly. But every measuring instrument searched with well-being was adapted from western tools. And there has not been any study used measuring instrument of well-being and interventions related to Traditional Korean Medicine. Conclusions : In order to handle the new wave of well-being and quality of life, research methods using tools to measure these variables need to be developed. Furthermore, it seems to be necessary that research on how to take advantage of Yangseng that is health concept of Traditional Korean Medicine.

• Journal of Society of Preventive Korean Medicine
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• v.20 no.3
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• pp.1-8
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• 2016

Objectives : There is a correlation between student's satisfaction of education and their occupation satisfaction. Therefore, Korean medical school students' satisfaction toward their education is important for their medical ability in Traditional Korean Medicine(TKM). The purpose of this study is to investigate TKM school students' satisfaction of education and their perceptions of TKM level. Methods : The questionnaire used in this study is consisted of questions about students' satisfaction and their perception toward issues about TKM. 168 cases were collected, and I analyzed 164 cases. Results : 43.9% of students think that the ratio of western medical courses to TKM courses in TKM school's curriculum is 'Proper'. 54.3% of students do not satisfy their curriculum. But, 51.2% of students would recommend high school students for entrance to TKM school. 77.9% of students think 'TKM doctor should use modern medical device'. 92.7% and 61.9% of students think 'Needed' toward 'Cooperation of western medicine and Korean medicine', and 'Medical unification' each. There are correlations ; (1)'recognition toward ratio of curriculum', (2)'satisfaction of curriculum', (3)'degree of recommendation to enter the TKM School', (4)'relation between TKM and Traditional Chinese Medicine(TCM) or Complementary and Alternative Medicine(CAM)'. Conclusions : Student's satisfaction of education is not quite high than satisfaction of TKM study itself. Most of respondents agreed usage of medical devices. The more they thought that they had curriculum for western medicine, the lesser they thought that medical unification was ont needed. Further studies are needed to assess satisfactions of students for their education with more accuracy results.