• Title/Summary/Keyword: Medical Department

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Positive Effects of Oral β-Glucan on Mucositis and Leukopenia in Colorectal Cancer Patients Receiving Adjuvant FOLFOX-4 Combination Chemotherapy

  • Karaca, Halit;Bozkurt, Oktay;Ozaslan, Ersin;Baldane, Suleyman;Berk, Veli;Inanc, Mevlude;Duran, Ayse Ocak;Dikilitas, Mustafa;Er, Ozlem;Ozkan, Metin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3641-3644
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    • 2014
  • The present study aimed to determine the effect of oral ${\beta}$-glucan on mucositis and leukopenia in 62 consecutive patients with colorectal cancer treated with an adjuvant FOLFOX-4 regimen. The patients were retrospectively evaluated in 2 groups: one group received ${\beta}$-glucan and the other did not (control group). Leucocytes, neutrophils, and platelets were evaluated before and 1 week after chemotherapy and oral mucositis and diarrhea were noted. Leucocyte and neutrophil counts after chemotherapy in the ${\beta}$-glucan group were $7,300/mm^3$ and $3,800/mm^3$, respectively, and the reductions, as compared to baseline, were not significant (p=0.673 and 0.784). The median platelet count was $264,000/mm^3$ after chemotherapy in the ${\beta}$-glucan group and the reduction, as compared to baseline, was borderline significant (p=0.048). In the control group, reduction in leucocyte, neutrophil, and platelet counts was statistically significant. Oral mucositis and diarrhea were less common in the ${\beta}$-glucan group. We conclude that ${\beta}$-glucan can be used to reduce the adverse effects of chemotherapy.

Improvement in emergency medical technician-basic training program : a review of the status of training institutions and designation criteria (2급 응급구조사 양성과정 개선방안 연구 : 양성기관 현황 및 지정기준 검토)

  • Lee, Nam-Jong;Shin, Dong-Min;Kim, Byung-Woo;Park, Si-Eun;Yoo, Eun-Ji;Yoon, Byoung-Gil;Yun, Seong-Woo;Yun, Hyeong-Wan;Lee, Kyoung-Youl;Choi, Jae-Woong;Hwang, Sung-Hoon
    • The Korean Journal of Emergency Medical Services
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    • v.23 no.2
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    • pp.139-151
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    • 2019
  • Purpose: To discuss the records and legal standards of emergency medical technician training institutions in Korea and abroad, to identify the problems, and to provide the basic resources for improving the EMT-basic training institutions. Methods: We received advice through an advisory meeting of experts (professors of department of emergency medical technicians) and interested parties (Korean Association of Emergency Medical Technicians, officials of emergency medical technician training institutions) and referred to various reports published by governments, official institutions, and other trustworthy organizations. Also, we communicated with the related experts abroad (3 countries) on the phone or by email for surveys. Results: Compared to the abroad, it is necessary to categorize the standards and procedures of designating the emergency medical technician training institutions in Korea and improve the management of training institutions to train competent emergency medical technicians. Conclusion: It is necessary to designate and manage continuously the emergency medical technician-basic training programs for the systematic primary healthcare service.

Identification of the DNA Binding Element of the Human ZNF333 Protein

  • Jing, Zhe;Liu, Yaping;Dong, Min;Hu, Shaoyi;Huang, Shangzhi
    • BMB Reports
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    • v.37 no.6
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    • pp.663-670
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    • 2004
  • ZNF 333 is a new and sole gene containing two KRAB domains which has been identified currently. It is a member of subfamilies of zinc finger gene complex which had been localized on chromosome 19p13.1. The ZNF333 gene mainly encodes a 75.5 kDa protein which contains 10 zinc finger domains. Using the methods of random oligonucleotide selection assay, electromobility gel shift assay and luciferase activity assay, we found that ZNF333 recognized the specific DNA core binding sequence ATAAT. Moreover, these data indicated that the KRAB domain of ZNF333 really has the ability of transcriptional repression.

Gastric Duplication Cysts in Adults: A Report of Three Cases

  • Kim, Su Mi;Ha, Man Ho;Seo, Jeong Eun;Kim, Ji Eun;Min, Byung Hoon;Choi, Min Gew;Lee, Jun Haeng;Kim, Kyung Mi;Choi, Dong Il;Sohn, Tae Sung;Bae, Jae Moon;Kim, Jae Jun;Kim, Sung;Lee, Jun Ho
    • Journal of Gastric Cancer
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    • v.15 no.1
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    • pp.58-63
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    • 2015
  • Gastric duplication cyst is a rare congenital anomaly of the gastrointestinal tract and is especially uncommon in adults. Most cases in adults are discovered incidentally on radiological examination or gastric endoscopy. Accurate diagnosis of these cysts before resection is difficult. Differential diagnoses are varied. Malignant transformation of a gastric duplication cyst is very rare. We present three cases of asymptomatic noncommunicating gastric duplication cysts in adults.

A Study on the Spatial Configuration Characteristics of Dental Department in Medical Center in Korea - Focused on the Medical Center in Seoul Area (한국 내 의과대학병원 내 치과의 공간구성특성에 관한 연구 - 서울지역 의과대학병원을 중심으로)

  • Jeong, Taejong
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.25 no.1
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    • pp.7-16
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    • 2019
  • Purpose: Analysis on the spatial configuration characteristics of dental department in medical center through examining outpatient department of medical center is necessary for the development of architectural planning of the dental healthcare system in Korea. This study has been performed to provide data for the planning of hospital architecture. Methods: Literature review of dental healthcare system and investigation on current status of dental department in medical center have been conducted. The plan and spatial configuration of seven medical centers in Seoul area have been analyzed. Results: The result of this study can be summarized in four points. The first one is that the clinical dental spaces are classified by dental school's dental hospital, dental department in medical center, dental hospital, private dental clinic, and public dental healthcare center in Korea. The second one is that the dental department in medical center is a result from medical law regulation and it is specified and subdivided with dental specialist system. The third one is that the types of the dental department in medical center are divided into independent type or comprehensive type according to the relationship with main outpatient department. The fourth one is that the spatial configuration of dental department in medical center is planned with 5-7 specialized departments and they are allocated in the dental department. Implications: In addition to the spatial configuration of dental department in medical center, it is necessary to analyze the other factors like circulation, relationship with other facilities in medical center to develop the dental healthcare system.