• The Journal of Pediatrics of Korean Medicine
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• v.12 no.1
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• pp.145-162
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• 1998

The purpose of this study was to determine the effects of oriental medical care on growth deficiency children. These cases were collected to investigate the effects of oriental medical care on growth deficiency children. So the cases were divided into 5 groups. The growth velocity was compared to a normal growth curve, and the results are as follows: 1. Oriental medical care was efficient when the epiphysial plates were not closed. 2. In female middle school beyond 1st grade students and in male middle school 3rd grade students who had almost closed epiphysial plates, the oriental medical care was not efficient and did not promote growth velocity. endothelium were used for the experiment using organ bath. 3. In the cases where the parent were very short, the effects of the oriental medical care to promote growth velocity was not efficient. 4. when we treated children of normal height, their growth velocity was over the normal growth curve. 5. In preschool aged children, oriental medical care was very efficient to promote children's growth. 6. The principle oriental medical care was to make balanced their body and digestive organs by using herb medicines that have the capability to promote the growth of the bones, and build strong muscles.

• BMB Reports
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• v.38 no.1
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• pp.28-33
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• 2005

A gene coding a novel isoform of carbamyl phosphate synthetase I (CPS1) was cloned from a human testicular library. As shown by cDNA microarray hybridization, this gene was expressed at a higher level in human adult testes than in fetal testes. The full length of its cDNA was 3831 bp, with a 3149 bp open reading frame, encoding a 1050-amino-acid protein. The cDNA sequence was deposited in the GenBank (AY317138). Sequence analysis showed that it was homologous to the human CPS1 gene. The putative protein contained functional domains composing the intact large subunit of carbamoyl phosphate synthetase, thus indicated it has the capability of arginine biosynthesis. A multiple tissue expression profile showed high expression of this gene in human testis, suggesting the novel alternative splicing form of CPS1 may be correlated with human spermatogenesis.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.49 no.4
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• pp.9-15
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• 2012

With the rise of internet and e-commerce, this is more applicable now than ever. People rely on computer networks to provide them with news, stock prices, e-mail and online shopping. People's credit card details, medical records and other personal information are stored on computer systems. Many companies have a web presence as an essential part of their business. The research community uses computer systems to undertake research and to disseminate findings. The integrity and availability of all these systems have to be protected against a number of threats. Amateur hackers, rival corporations, terrorists and even foreign governments have the motive and capability to carry out sophisticated attacks against computer systems. Therefore, the field of information and communication security has become vitally important to the safety and economic well being of society as a whole. This paper provides an overview of IDS and IPS, their functions, detection and analysis techniques. It also presents comparison of security capability and characteristics of IDPS techniques. This will make basis of IDPS(Intrusion Detection and Protection System) technology integration for a broad-based IDPS solutions

• Progress in Medical Physics
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• v.25 no.3
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• pp.185-192
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• 2014

The purpose of this study is to evaluate the results for the quality assurance through a statistical analysis on the output characteristics of linear accelerators belonging to Yeungnam University Medical Center by using the Shewhart-type chart, Exponentially weighted moving average chart (EWMA) chart, and process capability indices $C_p$ and $C_{pk}$. To achieve this, we used the output values measured using respective treatment devices (21EX, 21EX-S, and Novalis Tx) by medical physicists every month from September, 2012 to April, 2014. The output characteristics of treatment devices followed the IAEA TRS-398 guidelines, and the measurements included photon beams of 6 MV, 10 MV, and 15 MV and electron beams of 4 MeV, 6 MeV, 9 MeV, 12 MeV, 16MeV, and 20 MeV. The statistical analysis was done for the output characteristics measured, and was corrected every month. The width of control limit of weighting factors and measurement values were calculated as ${\lambda}=0.10$ and L=2.703, respectively; and the process capability indices $C_p$ and $C_{pk}$ were greater than or equal to 1 for all energies of the linear accelerators (21EX, 21EX-S, and Novalis Tx). Measured values of output doses with drastic and minor changes were found through the Shewhart-type chart and EWMA chart, respectively. The process capability indices $C_p$ and $C_{pk}$ of the treatment devices in our institution were, respectively, 2.384 and 2.136 for 21EX, 1.917 and 1.682 for 21EX-S, and 2.895 and 2.473 for Novalis Tx, proving that Novalis Tx has the most stable and accurate output characteristics.

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.197-198
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• 1998

We tested the capability of Pointwise Correlation Dimension(PD2), Approximate Entropy (ApEn) and LZ complexity, as alternative measures of a biological signal. For this purpose, we analyzed standard data and a healthy child's 24-hour heart rate variability. Our conclusion is as follows. First, PD2, ApEn and LZ complexity can be used for discerning chaotic attractor, white noise, and periodic signal. Second, these measures show different characteristics on day and night. Third, these measures can be used for detecting time-varying characteristics of biological signals.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.05
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• pp.143-146
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• 1996

An adaptive digital filtering of the electroencophalogram(EEG) is a successful way of suppressing mains interference, but it affects some of the frequency components of the signal, an artifact which not be acceptable in some cases of automatic EEG processing. The types of electrical artifact seen on EEG records is described. Those are the EOG and the PVC roller pump noise. And we study the method for cancelling these artifacts. The method does not need the reference channel, and are obtained by cascading the linear predictor and the noise canceller. The simulation results illustrate the performances of the presented method in terms of the capability of interferences suppression.

• BMB Reports
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• v.51 no.11
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• pp.572-577
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• 2018

Recent studies showed that the PD-1/PD-L1 checkpoint blockade is a dramatic therapy for melanoma by enhancing antitumor immune activity. Currently, major strategies for the PD-1/PD-L1 blockade have mainly focused on the use of antibodies and compounds. Seeking an alternative approach, others employ endogenous proteins as blocking agents. The extracellular domain of PD-1 (ePD1) includes the binding site with PD-L1. Accordingly, we constructed a PD-1-based recombinantly tailored fusion protein (dFv-ePD1) that consists of bivalent variable fragments (dFv) of an MMP-2/9-targeted antibody and ePD1. The melanoma-binding intensity and antitumor activity were also investigated. We found the intense and selective binding capability of the protein dFv-ePD1 to human melanoma specimens was confirmed by a tissue microarray. In addition, dFv-ePD1 significantly suppressed the migration and invasion of mouse melanoma B16-F1 cells, and displayed cytotoxicity to cancer cells in vitro. Notably, dFv-ePD1 significantly inhibited the growth of mouse melanoma B16-F1 tumor cells in mice and in vivo fluorescence imaging showed that dFv-ePD was gradually accumulated into the B16-F1 tumor. Also the B16-F1 tumor fluorescence intensity at the tumor site was stronger than that of dFv. This study indicates that the recombinant protein dFv-ePD1 has an intensive melanoma-binding capability and exerts potent therapeutic efficacy against melanoma. The novel format of the PD-L1-blocked agent may play an active role in antitumor immunotherapy.

• Journal of Korean Society for Quality Management
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• v.45 no.3
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• pp.463-481
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• 2017

Purpose: This study provide the matching mechanism between startup and business incubator to enhance managerial performance of business incubator. In addition, we propose the differentiation strategy for business incubator based on the needs of startups. Methods: In order to carry out the research, we surveyed 216 startups who already have invested in venture capitals and angel investors and currently residing in business incubator and 30 venture capitals and angel investors. Based on survey results, we develop a business incubator capability table matching startup with business incubator. Results: Satisfaction and importance of the supporting programs varied depending on the startup experience and startup lifecycle. As a result, we recommended a R&D center for machinery/material, bio/medical and electric/electronics startups and individual office for ICT and knowledge service startups. In addition, we suggested a differentiation strategy to BI in university specialized for machinery/material, privately operated BI for electric/electronic, (local)government, R&D center and individual office for knowledge service respectively. Conclusion: In this study, business incubator capability table is applied to match startup with business incubator and it could be applied to evaluate the current status of business incubator. Furthermore, it will help to establish a future strategic direction for business incubator.

• Medical Lasers
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• v.10 no.1
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• pp.1-6
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• 2021

Intravital microscopy is a high-resolution imaging technique based on laser-scanning two-photon and confocal microscopy, which allows dynamic 3D cellular-level imaging of various biological processes in a living animal in vivo. This unique capability allows biomedical researchers to directly verify a hypothesis in a natural in vivo microenvironment at the cellular level in a physiological setting. During the last decade, intravital microscopy has become an indispensable technique in several fields of biomedical sciences such as molecular and cell biology, immunology, neuroscience, developmental, and tumor biology. The most distinct advantage of intravital microscopy is its capability to provide a longitudinal view of disease progression at the cellular-level with repeated intravital imaging of a single animal over time by saving the images after each session.

• Imaging Science in Dentistry
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• v.42 no.2
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• pp.115-119
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• 2012

Today, ultrasound imaging is being widely used to assess soft tissue lesions in the maxillofacial region. However, ultrasound investigations of intra-osseous lesions are rare, especially for tumors of the jaws. This report emphasized the capability of this useful imaging modality in identification of the characteristics of malignant conditions involving the bone. Mesenchymal chondrosarcoama, one of the unusual malignant conditions of the jaw, was presented in a young male with significant facial swelling. Different imaging modalities parallel with the histopathologic investigation confirmed the diagnosis. Interestingly, destruction of the bony cortex and new bone formation with a characteristic "sun ray appearance", highly suggestive of sarcomas, was manifested on the ultrasonograph. Thus, this report presented the ultrasonographic features of chondrosarcoma of mandible and considered the ultrasonography to be a useful imaging modality to evaluate intra-osseous jaw lesions.