• 한국정보시스템학회지:정보시스템연구
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• 제31권2호
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• pp.179-196
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• 2022

Purpose The purpose of this study is to examine what expectations and mediating factors are needed as variables necessary for the intention to use logistics hollowing out, and at the same time, what factors strengthen medical SCM competitiveness. In order to develop competitive competency variables for medical institutions that affect the intention to use logistics cavitation, we would like to examine the key success factors applying AHP model analysis. Design/methodology/approach For AMOS analysis, we conducted an online survey of four universities and analyzed 212 samples. The analysis method used SPSS, and AMOS. We proposed several factors categorized as reliability, SCM advance, and scalability. Findings The results showed that all proposed variables (competitive competencies for HSCM, expected performance) had a significant impact on intention of physical distribution cooperation. According to the measurement methods proposed in this study, key success factors for strengthening the capacity of HSCM can increase the need for physical distribution cooperation through expected performance.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9635-9641
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• 2014

Background: This retrospective study was aimed to investigate the efficacy of prophylactic agents in hepatocellular carcinoma (HCC) patients receiving TACE and compare the difference between lamivudine and entecavir. Materials and Methods: A consecutive series of 203 HBV-related HCC patients receiving TACE were analyzed including 91 patients given prophylactic agents. Virologic events, defined as an increase in serum HBV DNA level to more than 1 log10 IU/ml higher than the nadir level, hepatitis flares due to HBV reactivation and progression free survival (PFS) were the main endpoints. Results: Some 48 (69.6%) reached virologic response. Prophylaxis significantly reduced virologic events (8.8% vs 58.0%, p=0.000) and hepatitis flares (1.1% vs 13.4%, p=0.001). Patients presenting undetectable HBV DNA levels displayed a significantly improved PFS as compared to those who never achieved undetectable HBV DNA. Prophylaxis and e-antigen positivity were the only significant variables associated with virologic events. In addition, prophylaxis was the only independent protective factor for hepatitis flares. Liver cirrhosis, more cycles of TACE, HBV DNA negativity, a lower Cancer of the Liver Italian Program score, non-metastasis and no hepatitis flares were protective factors for PFS. Prophylactic lamivudine demonstrated similar efficacy as entecavir. Conclusions: Prophylactic agents are efficacious for prevention of HBV reactivation in HCC patients receiving TACE. Achievement of undetectable HBV DNA levels displayed a significant capability in improving PFS. Moreover, persistent tumor residual lesions, positive HBV DNA and hepatitis B flares might be causes of tumor progression in these patients.

• 대한의용생체공학회:의공학회지
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• 제28권3호
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• pp.410-416
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• 2007

This paper presents quantitative analysis of a training system based on an unstable platform and a visual interactive system for improving sense of equilibrium. The training system consists of an unstable platform, a force plate, a safety harness, a monitoring device, and a personal-computer. To confirm the effects of the training system, fifteen young volunteers and five elderly volunteers went through a series of balance training using the system. During the training, we measured relevant parameters such as the time a subject maintain his or her center of pressure on a target, the time a subject moves his or her center of pressure to the target, and the mean absolute deviation of the trace before and after training with this system and training programs to evaluate the effects of the training. The results showed that the training system can successfully assess the gradual improvement of the postural control capability of the subject in the system and showed a possibility of improving balance of the subject. Moreover, the significant improvement in the postural capability of the elderly subject suggests that elderly subjects can benefit more from the training using the system for the improvement of sense of equilibrium.

• 한국콘텐츠학회논문지
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• 제21권11호
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• pp.543-552
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• 2021

마케팅-영업-인터페이스(MSI) 능력은 영업사원들이 시장에서의 지식과 경험을 보다 효과적으로 조직 내부 자원들과 소통하는 능력으로서 영업성과에 긍정적인 영향을 주는 것으로 알려져 있다. 본 연구는 제약회사 영업사원의 마케팅-영업-인터페이스(MSI) 능력이 직무만족도를 통해 영업성과에 영향을 미치는 매개효과를 분석하였다. 전국 제약회사 5곳의 영업사원을 대상으로 2021년 4월 15일부터 4월 23일까지 설문조사를 실시하였으며, 총 257부를 최종 분석에 사용하였다. 분석 결과 영업사원이 지각하는 MSI능력은 직무만족도 및 영업성과에 통계적으로 유의한 정(+)의 영향을 보였다. 또한 제약회사 영업사원이 지각하는 MSI능력은 직무만족도를 매개하여 영업성과에 통계적으로 유의한 정(+)의 영향을 보였다. 분석결과는 제약회사 영업사원의 영업성과 향상을 위해 MSI능력과 직무만족도의 중요성을 시사하며, 직무만족도의 매개효과에 주목하여 영업사원 관리와 관련된 방안 마련이 필요함을 보여준다.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제13권3호
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• pp.131-140
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• 2007

의료정보서비스로 인해 병원에서의 디지털화는 환자관리에 빠른 발전이 있었다. 여기에 더하여 병원 어디에서나 언제든지 의료정보서비스를 제공하려는 노력을 하고 있다. 유비쿼터스 환경에서의 주요 요구사항은 DICOM 표준을 이용한 영상 뷰어시스템과 의료정보서비스를 지원하는 서버시스템 간에 통신할 수 있는 기능이다. 본 논문은 의료정보서비스를 제공하기 위해 RFID 기술을 이용한 이동 단말기 기반의 원격 네트워킹 시스템을 기술한다. 전반적인 구성을 적용하기 위해 본 논문은 우선 DICOM 뷰어 시스템을 개발하였고, 환자 정보를 저장하기위한 데이타베이스를 구성하였으며 모바일 터미널 환경에서 서버/클라이언트 네트워킹 시스템을 구현하였다. 특히, 본 논문은 문자 기반 통신은 물론 의료영상 기반 통신의 가능성을 보여주었다.

• 한국인터넷방송통신학회논문지
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• 제13권6호
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• pp.161-166
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• 2013

최근 정보기술 발달로 산업 전 분야에서 IT 융합이 보편적으로 이루어지고 있다. 특히 의료IT 융합분야는 사용자 서비스 측면에서 많은 변화를 보이고 있다. 본 논문에서는 사용자 서비스 측면에 하나의 사례로 기존 종이처방전을 모바일을 이용한 QR코드로 전송할 수 있는 환경을 제안하고자 한다. QR코드는 종이처방전의 출력에서 전달, 보관하는 과정상의 부담을 최소화할 수 있다. 또한 정보 표현을 다양하고 폭넓게 활용할 수 있으며, 정보 복원과 암호화가 가능하므로 개인 정보 노출 및 변조의 위험을 최소화할 수 있는 미디어로 간주된다. 따라서 QR코드의 기능을 의료분야에 유합함으로서 사용자의 편의는 물론 정보의 기밀성, 저장능력을 발휘할 것으로 기대한다.

• Journal of Microbiology and Biotechnology
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• 제26권12호
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• pp.2184-2191
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• 2016

The time-consuming and high-cost preparation of soluble peptide-major histocompatibility complexes (pMHC) currently limits their wide uses in monitoring antigen-specific T cells. The single-chain trimer (SCT) of peptide-${\beta}2m$-MHC class I heavy chain was developed as an alternative strategy, but its gene fusion is hindered in many cases owing to the incompatibility between the multiple restriction enzymes and the restriction endonuclease sites of plasmid vectors. In this study, overlap extension PCR and one-step cloning were adopted to overcome this restriction. The SCT gene of the $OVA_{257-264}$ peptide-$(GS_4)_3-{\beta}2m-(GS_4)_4-H-2K^b$ heavy chain was constructed and inserted into plasmid pET28a by overlap extension PCR and one-step cloning, without the requirement of restriction enzymes. The SCT protein was expressed in Escherichia coli, and then purified and refolded. The resulting $H-2K^b/OVA_{257-264}$ complex showed the correct structural conformation and capability to bind with $OVA_{257-264}$-specific T-cell receptor. The overlap extension PCR and one-step cloning ensure the construction of single-chain MHC class I molecules associated with random epitopes, and will facilitate the preparation of soluble pMHC multimers.

• Journal of the Korean Data Analysis Society
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• 제20권6호
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• pp.2967-2980
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• 2018

본 연구에서는 의료 공급사슬 상에서 구매자에 해당하는 병원과 공급자와의 관계의 성과를 향상시킬 수 있는 방안에 대해 모색하고자 하였다. 보다 구체적으로, 거래기간과 병원의 규모에 해당하는 병상 수가 통제된 상황 하에서 구매자-공급자 간의 정보공유와 구매자가 인식한 공급자의 역량에 대한 신뢰가 구매자의 관계성과에 미치는 영향을 알아보고자 하였다. 아울러, 거래기간과 병상 수가 통제된 상태에서, 상호작용 공정성이 정보공유와 관계성과, 역량신뢰와 관계성과에 미치는 영향력에 대해 조절효과를 가지는지 파악하고자 하였다. 이를 위해 신뢰성 분석, 전체 탐색적 요인분석 및 확인적 요인분석, 판별타당성 분석을 거친 후 통제변수가 포함된 조절적 회귀분석을 수행하였다. 연구 결과, 구매자-공급자 간의 정보공유와 구매자가 인식한 공급자의 역량에 대한 신뢰는 모두 구매자의 관계성과에 긍정적인 영향력의 관계가 있음을 확인할 수 있었다. 아울러, 상호작용 공정성의 조절효과와 관련해서는 정보공유와 관계성과의 관계에서는 상호작용 공정성이 조절효과가 나타나지 않았지만, 역량신뢰와 관계성과의 관계에서는 상호작용 공정성이 조절효과가 있음을 실증적으로 확인할 수 있었다.

• 한국병원경영학회지
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• 제17권3호
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• pp.1-22
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• 2012

The purpose of this study is to analyze the mediating effect of informatization level between characteristics of introducing information system and organizational performance in hospital settings, and to provide suggestions to improve the performance level of strategic information system of hospitals. In order to achieve study purpose, a causal path model was developed and empirically tested. Data were collected from 746 managers of 92 hospitals keeping information system in Busan, Ulsan and Kyungnam Province using self-administered structured questionnaire. Major results of this study were as follows; The results of the path analysis showed that organizational characteristics variables except informatization strength within health industry had significant effects on informatization level, and had indirect effects on organizational performance mediated by informatization level. On the other hand, informatization level, especially revelation capability among informatization level variables, was found to have significant direct effect on organizational performance. These results of empirical test imply that informatization level variables are both important affecting factors on organizational performance and mediating factors between organizational characteristics and organizational performance. Therefore, in order to increase organizational performance, measures improving informatization level should be developed and carried out continuously. And, especially, focusing on building and strengthening revelation capability is crucial to those efforts.

• 한방안이비인후피부과학회지
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• 제29권4호
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• pp.24-33
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• 2016

Objectives : This study is to investigate the anti-inflammatory and anti-oxidant effects of Tongbi-san extract (TS) on RAW264.7 macrophages using by cell cytotoxicity, Nitric Oxide (NO) and Prostaglandin $E_2$ ($PGE_2$) production and 1,1-diphenyl-2-picryl ghdrazyl (DPPH) free radical scavenging capability. Methods : Cell cytotoxicity was measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The production of NO was measured by Griess assay. The production of $PGE_2$ was measured by immunoassay. And the anti-oxidant activity was measured by the DPPH method. Results : TS did not increased significantly compared to the TS untreated group in the cell cytotoxicity. TS inhibited NO and $PGE_2$ production in lipopolysaccharide-stimulated RAW 264.7 cells. TS had the DPPH free radical scavenging capability. Conclusion : The anti-inflammtory and anti-oxidant effects of TS may be use for a treatment of anti-inflammatory diseases.