• The Journal of Information Systems
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• v.31 no.2
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• pp.179-196
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• 2022

Purpose The purpose of this study is to examine what expectations and mediating factors are needed as variables necessary for the intention to use logistics hollowing out, and at the same time, what factors strengthen medical SCM competitiveness. In order to develop competitive competency variables for medical institutions that affect the intention to use logistics cavitation, we would like to examine the key success factors applying AHP model analysis. Design/methodology/approach For AMOS analysis, we conducted an online survey of four universities and analyzed 212 samples. The analysis method used SPSS, and AMOS. We proposed several factors categorized as reliability, SCM advance, and scalability. Findings The results showed that all proposed variables (competitive competencies for HSCM, expected performance) had a significant impact on intention of physical distribution cooperation. According to the measurement methods proposed in this study, key success factors for strengthening the capacity of HSCM can increase the need for physical distribution cooperation through expected performance.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9635-9641
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• 2014

Background: This retrospective study was aimed to investigate the efficacy of prophylactic agents in hepatocellular carcinoma (HCC) patients receiving TACE and compare the difference between lamivudine and entecavir. Materials and Methods: A consecutive series of 203 HBV-related HCC patients receiving TACE were analyzed including 91 patients given prophylactic agents. Virologic events, defined as an increase in serum HBV DNA level to more than 1 log10 IU/ml higher than the nadir level, hepatitis flares due to HBV reactivation and progression free survival (PFS) were the main endpoints. Results: Some 48 (69.6%) reached virologic response. Prophylaxis significantly reduced virologic events (8.8% vs 58.0%, p=0.000) and hepatitis flares (1.1% vs 13.4%, p=0.001). Patients presenting undetectable HBV DNA levels displayed a significantly improved PFS as compared to those who never achieved undetectable HBV DNA. Prophylaxis and e-antigen positivity were the only significant variables associated with virologic events. In addition, prophylaxis was the only independent protective factor for hepatitis flares. Liver cirrhosis, more cycles of TACE, HBV DNA negativity, a lower Cancer of the Liver Italian Program score, non-metastasis and no hepatitis flares were protective factors for PFS. Prophylactic lamivudine demonstrated similar efficacy as entecavir. Conclusions: Prophylactic agents are efficacious for prevention of HBV reactivation in HCC patients receiving TACE. Achievement of undetectable HBV DNA levels displayed a significant capability in improving PFS. Moreover, persistent tumor residual lesions, positive HBV DNA and hepatitis B flares might be causes of tumor progression in these patients.

• Journal of Biomedical Engineering Research
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• v.28 no.3
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• pp.410-416
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• 2007

This paper presents quantitative analysis of a training system based on an unstable platform and a visual interactive system for improving sense of equilibrium. The training system consists of an unstable platform, a force plate, a safety harness, a monitoring device, and a personal-computer. To confirm the effects of the training system, fifteen young volunteers and five elderly volunteers went through a series of balance training using the system. During the training, we measured relevant parameters such as the time a subject maintain his or her center of pressure on a target, the time a subject moves his or her center of pressure to the target, and the mean absolute deviation of the trace before and after training with this system and training programs to evaluate the effects of the training. The results showed that the training system can successfully assess the gradual improvement of the postural control capability of the subject in the system and showed a possibility of improving balance of the subject. Moreover, the significant improvement in the postural capability of the elderly subject suggests that elderly subjects can benefit more from the training using the system for the improvement of sense of equilibrium.

• The Journal of the Korea Contents Association
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• v.21 no.11
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• pp.543-552
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• 2021

Marketing-Sales-Interface(MSI) capabilities are known to have a positive impact on sales performance as pharmaceutical salespersons's ability to more effectively communicate their knowledge and experience in the market with internal resources in the organization. This study was conducted to analyze the mediating effect of pharmaceutical salespersons marketing-sales-interface (MSI) ability on sales performance through job satisfaction. Salespersons from five pharmaceutical companies nationwide were studied, and the survey was carried out for about a week from April 15 to April 23, 2021, and a total of 257 questionnaires were used for the final analysis. The main analysis result of this research is that, first, the MSI capabilities that pharmaceutical salespersons perceive showed a statistically significant positive (+) impact on job satisfaction and sales performance. Also, the MSI capabilities that pharmaceutical salespersons perceive had a statistically significant positive (+) impact on sales performance by mediating job satisfaction. The analysis results suggest the importance of MSI capability and job satisfaction for improving the sales performance of pharmaceutical salespersons. This study aims to come up with measures and provide baseline data related to salesperson management by paying attention to the mediating effects of job satisfaction on the impact of MSI on sales performance.

• Journal of KIISE:Computing Practices and Letters
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• v.13 no.3
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• pp.131-140
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• 2007

A general medical information service in hospitals recently has been rapidly developed in the effective patient management due to the digitalization. In addition, the hospitals make an effort to support the medical information service in ubiquitous environment. A key requirement in ubiquitous environment is the ability to communicate between the image viewer system using the DICOM standard and a server system to support the medical information service. This paper describes a remote networking system based on the mobile terminal with RFID technology for the medical information service. In order to apply the overall configuration, we first implemented the DICOM viewer system, configured the database to store the patient information, and realized the server/client networking system in mobile terminal environment. In particular, this paper showed the capability for the medical image-based communication as well as the text-based communication.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.13 no.6
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• pp.161-166
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• 2013

With recent development in information technology, IT convergence has been achieved ubiquitously in all areas of industry. In particular, there have been a lot of changes in medical IT conversion sector in terms of user service. In this regard, this paper attempts to propose an environment in which the existing paper prescription can be transferred in the form of QR codes using mobile handsets as one of practices from the perspective of user service. QR codes can minimize the burden resulting from the process of the output, delivery and storage of paper prescriptions. In addition, they can utilize the representation of the information in a wide variety of ways, and they are considered to be media that can minimize the risk of personal information exposure and falsification due to the restoration and encryption of the information. Accordingly, the application of QR codes to the medical field is expected to improve confidentiality ad storage capability of the information, along with users' convenience.

• Journal of Microbiology and Biotechnology
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• v.26 no.12
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• pp.2184-2191
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• 2016

The time-consuming and high-cost preparation of soluble peptide-major histocompatibility complexes (pMHC) currently limits their wide uses in monitoring antigen-specific T cells. The single-chain trimer (SCT) of peptide-${\beta}2m$-MHC class I heavy chain was developed as an alternative strategy, but its gene fusion is hindered in many cases owing to the incompatibility between the multiple restriction enzymes and the restriction endonuclease sites of plasmid vectors. In this study, overlap extension PCR and one-step cloning were adopted to overcome this restriction. The SCT gene of the $OVA_{257-264}$ peptide-$(GS_4)_3-{\beta}2m-(GS_4)_4-H-2K^b$ heavy chain was constructed and inserted into plasmid pET28a by overlap extension PCR and one-step cloning, without the requirement of restriction enzymes. The SCT protein was expressed in Escherichia coli, and then purified and refolded. The resulting $H-2K^b/OVA_{257-264}$ complex showed the correct structural conformation and capability to bind with $OVA_{257-264}$-specific T-cell receptor. The overlap extension PCR and one-step cloning ensure the construction of single-chain MHC class I molecules associated with random epitopes, and will facilitate the preparation of soluble pMHC multimers.

• Journal of the Korean Data Analysis Society
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• v.20 no.6
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• pp.2967-2980
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• 2018

In this study, we intended to find out how to improve the relationship performance between a hospital who is a buyer and its suppliers in the medical supply chain. For specific, in control of the transaction period and the number of bed, we investigated the effect of information sharing between a buyer and its suppliers along with the trust for the suppliers' capabilities perceived by the buyer on the buyer's relationship performance. In addition, in control of the transaction period and the number of bed, we also examined the influences of moderating effect of the interactional justice on the relations between information sharing and relationship performance, and between capability-trust and relationship performance. For this, we conducted reliability analysis, exploratory/confirmatory factor analyses, discriminant validity analysis, and moderated multiple regression analysis including control variables. Our results showed that there are positive effects of information sharing between a buyer and suppliers, and the buyer's perceived trust for the suppliers' capability on the relationship performance while controlling the transaction period and the number of bed. Besides, we empirically confirmed that there was the moderating effect of the interactional justice on the relations between capability-trust and relationship performance, whereas we could not find that statistically significant moderating effect of the interactional justice on the relations between information sharing and relationship performance.

• Korea Journal of Hospital Management
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• v.17 no.3
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• pp.1-22
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• 2012

The purpose of this study is to analyze the mediating effect of informatization level between characteristics of introducing information system and organizational performance in hospital settings, and to provide suggestions to improve the performance level of strategic information system of hospitals. In order to achieve study purpose, a causal path model was developed and empirically tested. Data were collected from 746 managers of 92 hospitals keeping information system in Busan, Ulsan and Kyungnam Province using self-administered structured questionnaire. Major results of this study were as follows; The results of the path analysis showed that organizational characteristics variables except informatization strength within health industry had significant effects on informatization level, and had indirect effects on organizational performance mediated by informatization level. On the other hand, informatization level, especially revelation capability among informatization level variables, was found to have significant direct effect on organizational performance. These results of empirical test imply that informatization level variables are both important affecting factors on organizational performance and mediating factors between organizational characteristics and organizational performance. Therefore, in order to increase organizational performance, measures improving informatization level should be developed and carried out continuously. And, especially, focusing on building and strengthening revelation capability is crucial to those efforts.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.4
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• pp.24-33
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• 2016

Objectives : This study is to investigate the anti-inflammatory and anti-oxidant effects of Tongbi-san extract (TS) on RAW264.7 macrophages using by cell cytotoxicity, Nitric Oxide (NO) and Prostaglandin $E_2$ ($PGE_2$) production and 1,1-diphenyl-2-picryl ghdrazyl (DPPH) free radical scavenging capability. Methods : Cell cytotoxicity was measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The production of NO was measured by Griess assay. The production of $PGE_2$ was measured by immunoassay. And the anti-oxidant activity was measured by the DPPH method. Results : TS did not increased significantly compared to the TS untreated group in the cell cytotoxicity. TS inhibited NO and $PGE_2$ production in lipopolysaccharide-stimulated RAW 264.7 cells. TS had the DPPH free radical scavenging capability. Conclusion : The anti-inflammtory and anti-oxidant effects of TS may be use for a treatment of anti-inflammatory diseases.