• The Korean Journal of Emergency Medical Services
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• v.12 no.3
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• pp.87-98
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• 2008

Purpose : This study was designed to figure out the necessity of continuing basic CPR education for the higher grade students of elementary school. The assessment contents were knowledge, practice ability, precision level of CPR skills and continuation of the educational efficiency. Methods : Twenty two students of 4th and 5th grade of elementary school in K city in Chungcheongnam-do were recruited for this study. The study method was a control group of non-synchronized design. A preliminary study was done on October 27 in 2006. The main study was performed from February 14 to May 11 in 2007. The researcher adopted the method of Kyung-hui, Kang (1998) such as awareness, attitude and knowledge in control group, emergency medical technician test protocol, Anne/SkillReporter$^{(R)}$ in case of the basic CPR knowledge. Four times of measures were done in shortly after practicing CPR, 4 weeks after the education, 8 weeks after the education, and 12 weeks after the education. By using SPSS/PC+ (version 12.0), the researcher analyzed the collected data based on frequency, percentage, repeated measurement, ANOVA (analysis of variance), and sidak (multiple comparison - sidak). Results : 1) The confidence of people in the control group in terms of practicing CPR showed a statistically meaningful difference (t = 10.230, p = .000) before/after CPR education. Therefore, hypothesis No.1-1 was accepted. 2) The educational necessity of people in the control group showed no statistically meaningful difference (t = -1.695, p = 0.105) before/after CPR education. Therefore, hypothesis No.1-2 was rejected. 3) The knowledge points of people in the control group showed a statistically meaningful difference (t = -7.731, p = .000) before/after CPR education. Therefore, hypothesis No.2 was accepted. 4) The confidence of people in the control group in terms of practicing CRP showed no meaningful difference (F = 2.789, p = 0.072) as time passed. Therefore, hypothesis No.3 was rejected. 5) The knowledge of people in the control group showed a meaningful difference (F = 9.090, p = .000) as time passed. Therefore, hypothesis No.4 was accepted. 6) The capability of people in the control group in terms of practicing CPR showed a statistically meaningful difference (F = 42.795, p = .000) as time passed. Therefore, hypothesis No.5 was accepted. 7) The precision level of CPR skill of people in the control group showed a statistically meaningful difference (F = 25.198, p = .000) as time passed. Therefore, hypothesis No.6-1 was accepted. 8) The precision level of chest compression skill of people in the control group showed a statistically meaningful difference (F = 5.188, p = .003). Therefore, hypothesis No.6-2 was accepted. Conclusion : In a nutshell, CPR education for the 4th and 5th graders of elementary schools had an influence on their confidence in practicing CPR and on their knowledge. This study showed that as time passed. the educational effect declined in terms of knowledge point, capability of practicing CPR, and the precision level of CRP skill. The results of the study could be postulated into the fact that re-education within 8 weeks after the first education was essential to retaining the educational effect. Therefore, we need to vitalize the CPR education for elementary school students repeatedly on a regular basis in order to continue the educational effect after they were grown-ups and to make them play their roles as a first aider.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.sup3
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• pp.155-160
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• 2016

Breast cancer (BC) is the second most common cancer in the world and by far the most frequent cancer among women, with an estimated 1.67 million new cancer cases diagnosed in 2012 (25% of all cancers). Polygene expression analysis is used to predict the prognosis and determine the most appropriate treatment regimen. The objective of this study was to examine the gene expression profiles of SIRT3, HRAS, LSP1, SCUBE2 and AP2A2 in Iranian women with BC.A total of 136 patients including healthy controls were categorized into three groups based on the relapse of the disease. Expression of desired genes in formalin-fixed, paraffin embedded tissues collected from all groups of participants was analyzed via the RT PCR method. RNA extraction and cDNA synthesis were performed then real-time quantitative PCR was carried out. Gene expression analysis revealed that the expression of SIRT3 was equal among patient and control groups. LSP1 was down regulated in all patient groups relative to controls but reduced expression in the metastatic group relative to the non-metastatic one was not significant. HRAS was significantly overexpressed in total and metastatic tumor samples versus normal but not in non-metastatic cases. SCUBE2 expression showed significant over-expression in both overall tumor samples and the non-metastatic group as compared to normal tissues. Gene expression level of AP2A2 in all groups was not detectable. Our data are compatible with a tumor suppressor role of LSP1 related to potential prognostic factor for tumor recurrence and outcome. This study for the first time assayed the prognostic value and changes in the expression of SIRT3, LSP1, HRAS, SCUBE2 and AP2A2 genes in women with breast cancer in the Iranian population and findings confirmed potential biomarker and prognostic capability of these genes. Such expression profiling data can critically improve prognosis and treatment decisions in cancer patients.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.1259-1264
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• 2007

Microstereolithography technology has potential capability for fabrication of 3D microstructures. It evolved from conventional SLA which is one of the RP processes. In a microstereolithography process, 3D microstructures can be easily fabricated by continuously stacking 2D layer which is photopolymerized using a liquid prepolymer. Combination between biocompatible/biodegradable photocurable prepolymer and 3D complex fabrication in microstereolithography makes broad application areas such as medical, pharmaceutic, and bio devices. In particular, a 3D microneedle for transdermal drug delivery and a scaffold for tissue engineering are fabricated using this technology. In this paper, the authors address development of microstereolithography system adapted to large surface and fabrication of various microstructures. In addition, to apply human body we suggest a biodegradable 3D microneedle and a scaffold using biodegradable photocurable prepolymer.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.403-404
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• 2007

Compound eyes in nature present intriguing topics in physiological optics due to their unique optical scheme for imaging. For example, a bee's eye has thousands of integrated photonic units called ommatidia spherically arranged along a curvilinear surface so that each unit points in a different direction. The omni-directionally arranged ommatidium collects incident light with a narrow range of angular acceptance and independently contributes to the capability of wide field-of-view (FOV) detection. Artificial implementation of compound eyes has attracted a great deal of research interest because the wide FOV exhibits a huge potential for medical, industrial, and military applications. So far, imaging with a FOV over $90^{\circ}$ has been achieved only with fisheye lenses which rely on bulky and expensive multiple lenses and require stringent alignment. In this talk, we will discuss about the spherical 3D arrangement of the photonic structures of biologically inspired artificial compound eyes in a small form-factor to have and the functional and anatomical similiarity with natural compound eyes.

• Journal of Biomedical Engineering Research
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• v.15 no.3
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• pp.355-364
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• 1994

The most important requirement for the controller of a prosthetic arm is that it has a high fidelity discriminator where the motion control may be performed open loop using EMG signals as a control source. Therefore, it is very effective method to reduce the influence of misclassification of classifier for the total system performance. This paper presents the new function discrimination method which combines MLP classifier and frizzy filter by stages for the requirement. The major advantage of MLP is a consistent learning capability for the easy adaptation to environments. The fuzzy filter uses all informations of MLP outputs and prior EMG activity informations which increase as the experience increases. That property is superior to one which uses maximum output of MLP in view of information amounts and quality. Simulation result shows that proposed method is superior to the probabilistic model, MLP model and the combined model of both in the respect of discrimination quaity.

• Journal of Biomedical Engineering Research
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• v.30 no.2
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• pp.113-121
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• 2009

This study aims at designing and evaluating light source devices that can stably generate light with various wavelengths in order to make possible PDD using a photosensitizer and diagnosis using auto-fluorescence. The light source was a Xenon lamp and filter wheel, composed of an optical output control through Iris and filters with several wavelength bands. It also makes the inducement of auto-fluorescence possible because it is designed to generate a wavelength band of 380-420nm, 430-480nm, and 480-560nm. The transmission part of the light source was developed to enhance the efficiency of light transmission. To evaluate this light source, the characteristics of light output and wavelength band were verified. To validate the capability of this device as PDD, the detection of auto-fluorescence using mouse models was performed.

• Proceedings of the KOSOMBE Conference
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• v.1990 no.11
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• pp.48-51
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• 1990

A new in vivo high resolution imaging method which is performed with a newly developed three channel surface gradient coil (SGC) is described. The surface gradient coil can produce more than an order of magnitude stronger gradient fields with good linearity within a limited imaging region. To increase the signal to noise ratio (SNR), we have developed an RF coil integrated surface gradient coil set. In this paper, the geometrical structures and characteristics of the proposed surface gradient coil are discussed and experimentally obtained high resolution images ($50\;{\mu}m$ to $100\;{\mu}m$) of a water filled phantom and a human volunteer's knee using the new surface RF coil integrated SGC set are presented for the demonstration of the in vivo high resolution imaging capability of the new imaging method.

• Proceedings of the KOSOMBE Conference
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• v.1985 no.06
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• pp.15-19
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• 1985

This study deals with a kind of signal processing, Kalman filtering techniques, which are applied to ultrasound signal to improve resolution capability. The main advantage of Kalman filter algorithm for the analysis of reflected ultrasound signal is its recursive structure which can be easily adapted to time-varing system. In state-space description of the system, the 6th order system produces the best spectral approximation to the source pulse. As a result of spectrum analysis, 6th order estimator for two closely spaced (0.5mm) reflectors enhance resolution by 4dB - 10dB. By using this result, the possibility to detect even minute tumor is found.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2010.06a
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• pp.138-138
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• 2010

X-ray systems for medical treatment use noninvasive procedures. I fabricated a high tension generator of a full-wave rectification type using a LC resonant inviter. It is said that a full-wave rectifying X-ray equipment such as the fabricated system can shorten initiating period and be precision control because of stable output, compared with the X-ray equipment of a half wave rectifying type used in the usual clinical medicine. In order to evaluate the capability of the fabricated high tension generator, I performed exposure dose characteristics experiments.

• Journal of International Society for Simulation Surgery
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• v.2 no.2
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• pp.52-57
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• 2015

Virtual Reality makes a virtual environment more realistic and, furthermore, it provides a variety of experiences which we cannot have in reality. A drastic growth of GPU performance and increase of computing capability make virtual environment more realistic than ever. One important element of constructing virtual environment is to animate 3D characters. Many researchers have been studying 3D characters animating and a myriad of methods have been proposed to make them more realistic. In this paper, we discuss the technologies and characteristics of 3D character animation. We believe that realistic characters in Virtual Reality will be applied to various fields: education, film and game industry, business and, particularly, medical area such as telemedicine, virtual surgery, etc.