• Journal of the Korean Society of Radiology
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• v.85 no.4
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• pp.714-726
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• 2024

Researchers have developed various algorithms utilizing artificial intelligence (AI) to automatically and objectively diagnose patterns and extent of pulmonary emphysema or interstitial lung diseases on chest CT scans. Studies show that AI-based quantification of emphysema on chest CT scans reveals a connection between an increase in the relative percentage of emphysema and a decline in lung function. Notably, quantifying centrilobular emphysema has proven helpful in predicting clinical symptoms or mortality rates of chronic obstructive pulmonary disease. In the context of interstitial lung diseases, AI can classify the usual interstitial pneumonia pattern on CT scans into categories like normal, ground-glass opacity, reticular opacity, honeycombing, emphysema, and consolidation. This classification accuracy is comparable to chest radiologists (70%-80%). However, the results generated by AI are influenced by factors such as scan parameters, reconstruction algorithms, radiation doses, and the training data used to develop the AI. These limitations currently restrict the widespread adoption of AI for quantifying pulmonary emphysema and interstitial lung diseases in daily clinical practice. This paper will showcase the authors' experience using AI for diagnosing and quantifying emphysema and interstitial lung diseases through case studies. We will primarily focus on the advantages and limitations of AI for these two diseases.

• Korea Journal of Hospital Management
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• v.23 no.2
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• pp.54-66
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• 2018

Purpose: This study was to figure out relationships of perceived Technology Readiness Index(TRI), usefulness, acceptance intension, and the recognition of substitute employment of medical personnel on the artificial intelligence (AI) and internet of things (IoT) among main technologies. Methodology: To achieve the purpose, this study utilized structured survey tools to conduct a questionnaire survey of nursing, administrative and medical technology professionals at six university hospitals in Korea metropolitan area. A PLS(Partial Least Square) Path analysis was utilized To analyze the material. Findings: In the relation with the technology readiness and perceived usefulness, it had a positive influence to the perceived usefulness when the optimism and innovativeness were higher and the discomfort was lower. In the relation with the technology readiness and acceptance intension, it showed a positive influence when the innovativeness was higher and the discomfort was lower. In the relation with the perceived usefulness and acceptance intension, it had a positive influence to the acceptance intension when the perceived usefulness was higher. In the relation with the acceptance intension and the recognition of substitute employment, it showed a positive influence to the recognition of substitute employment when the acceptance intension was higher. Practical Implications: Judging based on the above study results and reference reviews, it confirmed that it is necessary to prepare in the level of hospital organization in the $4^{th}$ Industrial Revolution. They should increase the efficiency of human resources through the technological factors or changes of employment types for the additional demands of human resources to handle increasing medical demands or induce to secure necessary abilities which are changing at the right time by performing the $4^{th}$ Industrial Revolution related re-training continuously to develop the value of existing human resources.

• Journal of Biomedical Engineering Research
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• v.44 no.2
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• pp.125-138
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• 2023

The development of AI systems for radiation therapy is important to improve the accuracy, effectiveness, and safety of cancer treatment. The current system has the disadvantage of monitoring patients using CCTV, which can cause errors and mistakes in the treatment process, which can lead to misalignment of radiation. Developed the PMRP system, an AI automation system that uses depth cameras to measure patient's fine movements, segment patient's body into parts, align Z values of depth cameras with Z values, and transmit measured feedback to positioning devices in real time, monitoring errors and treatments. The need for such a system began because the CCTV visual monitoring system could not detect fine movements, Z-direction movements, and body part movements, hindering improvement of radiation therapy performance and increasing the risk of side effects in normal tissues. This study could provide the development of a field of radiotherapy that lags in many parts of the world, along with the economic and social importance of developing an independent platform for radiotherapy devices. This study verified its effectiveness and efficiency with data through phantom experiments, and future studies aim to help improve treatment performance by improving the posture correction mechanism and correcting left and right up and down movements in real time.

• Imaging Science in Dentistry
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• v.54 no.3
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• pp.232-239
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• 2024

Purpose: The use of artificial intelligence (AI) and deep learning algorithms in dentistry, especially for processing radiographic images, has markedly increased. However, detailed information remains limited regarding the accuracy of these algorithms in detecting mandibular fractures. Materials and Methods: This meta-analysis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Specific keywords were generated regarding the accuracy of AI algorithms in detecting mandibular fractures on radiographic images. Then, the PubMed/Medline, Scopus, Embase, and Web of Science databases were searched. The Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) tool was employed to evaluate potential bias in the selected studies. A pooled analysis of the relevant parameters was conducted using STATA version 17 (StataCorp, College Station, TX, USA), utilizing the metandi command. Results: Of the 49 studies reviewed, 5 met the inclusion criteria. All of the selected studies utilized convolutional neural network algorithms, albeit with varying backbone structures, and all evaluated panoramic radiography images. The pooled analysis yielded a sensitivity of 0.971 (95% confidence interval [CI]: 0.881-0.949), a specificity of 0.813 (95% CI: 0.797-0.824), and a diagnostic odds ratio of 7.109 (95% CI: 5.27-8.913). Conclusion: This review suggests that deep learning algorithms show potential for detecting mandibular fractures on panoramic radiography images. However, their effectiveness is currently limited by the small size and narrow scope of available datasets. Further research with larger and more diverse datasets is crucial to verify the accuracy of these tools in in practical dental settings.

• Parasites, Hosts and Diseases
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• v.57 no.2
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• pp.101-115
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• 2019

The pathogenesis of cerebral malaria is biologically complex and involves multi-factorial mechanisms such as microvascular congestion, immunopathology by the pro-inflammatory cytokine and endothelial dysfunction. Recent data have suggested that a pleiotropic T-cell immunomodulatory protein (TIP) could effectively mediate inflammatory cytokines of mammalian immune response against acute graft-versus-host disease in animal models. In this study, we identified a conserved homologue of TIP in Plasmodium berghei (PbTIP) as a membrane protein in Plasmodium asexual stage. Compared with PBS control group, the pathology of experimental cerebral malaria (ECM) in rPbTIP intravenous injection (i.v.) group was alleviated by the downregulation of pro-inflammatory responses, and rPbTIP i.v. group elicited an expansion of regulatory T-cell response. Therefore, rPbTIP i.v. group displayed less severe brain pathology and feverish mice in rPbTIP i.v. group died from ECM. This study suggested that PbTIP may be a novel promising target to alleviate the severity of ECM.

• The Journal of the Convergence on Culture Technology
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• v.5 no.2
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• pp.177-182
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• 2019

As progress of technology, Artificial Intelligence is applied in various fields of industry such as finance, production, medical treatment, service, art by changing the way they look continuously. As AI is progressive area, We have to know what kind of changing is merged in human society by AI. In this paper, through the investigations of Artificial Intelligence's concept and the way Artificial Intelligence's technology is implemented in modern industry, we studied positive effect and negative effect of AI. By this study, In conclusion, by realizing how close Artificial Intelligence had come to our life, we can prepare to seek a foothold to deal with this Artificial Intelligence.

• Proceedings of the Korea Information Processing Society Conference
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• 2021.11a
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• pp.779-782
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• 2021

Survival time analysis is one of the main methods used by the pathologist to prognosis for cancer patients. In this paper, we strive to estimate the individual survival time of Adenocarcinoma (ADC) lung cancer patients from pathological images by adopting the convolutional neural network called the SurvPatchV1 model. First, we extracted tissue patches from the whole-slide images (WSI) to deal with extremely large dimensions of WSI. Then the survival time of each patch is estimated through the SurvPatchV1 model. Finally, the individual survival time of each patient is computed. The proposed method is trained and tested on the subset of the NLST dataset for ADC lung cancer. The result demonstrates that our model can obtain all tissue information in lieu of only tumor information in a whole pathological image to estimate the individual survival time.

• Journal of Korea Society of Digital Industry and Information Management
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• v.19 no.4
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• pp.97-115
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• 2023

In South Korea, chronic kidney disease(CKD) impacts around 4.6 million adults, leading to a high reliance on hemodialysis. For effective dialysis, vascular access is crucial, with decisions about vascular surgeries often made during dialysis sessions. Anticipating these needs could improve dialysis quality and patient comfort. This study investigates the use of Artificial Intelligence(AI) to predict the timing of surgeries for dialysis vessels, an area not extensively researched. We've developed an AI algorithm using predictive maintenance methods, transitioning from machine learning to a more advanced deep learning approach with Long Short-Term Memory(LSTM) models. The algorithm processes variables such as venous pressure, blood flow, and patient age, demonstrating high effectiveness with metrics exceeding 0.91. By shortening the data collection intervals, a more refined model can be obtained. Implementing this AI in clinical practice could notably enhance patient experience and the quality of medical services in dialysis, marking a significant advancement in the treatment of CKD.

• Korean Journal of Acupuncture
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• v.41 no.1
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• pp.27-32
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• 2024

Objectives : This study developed an AI-based patient chatbot and examined the usability and educational effectiveness of the chatbot in the context of Korean medicine education. Methods : The patient chatbot was developed using the AI chatbot builder 'Danbee', and a total of five experts were surveyed and interviewed to determine the usability, effectiveness, advantages, disadvantages, and improvement points of the chatbot. Results : The patient chatbot was found to have high usability and educational effectiveness. The advantages of the patient chatbot were 1) it provided students with practical experience in performing clinical skills, 2) it provided instructors with assessment materials while reducing their teaching burden, and 3) it could be effectively used for horizontal and vertical integration education. The disadvantages and improvements of the patient chatbot were 1) improving the accuracy of intention inference, 2) providing students with specific instructions for problem-solving activities, and 3) providing assessment results and feedback about students' activities. Conclusions : This study is significant in that it proposes a new training method to overcome the limitations of the existing doctor-patient simulation. It is hoped that this study will stimulate further research on the improvement of students' clinical skills using artificial intelligence.

• Journal of Information Technology Applications and Management
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• v.28 no.1
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• pp.1-12
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• 2021

The purpose of this study is to analyze the medical ecosystem in the post-corona era. In addition, this study introduces a new medical CRM model that allows primary-level hospitals to overcome the economic difficulties and to occupy a competitive advantage in the post-corona era. The medical environment in the post-corona era is expected to be changed by non-face-to-face treatment, reinforcement of public medical care, the transformation of a medical system centered on the primary-level hospitals, and the use of AI and big data technologies. The medical CRM model presented in this study emphasizes the establishment of mutual customer relationships through close information exchange between patients, primary-level hospital, and the government. In the post-corona era, primary-level hospitals should not simply be approached as private hospital pursuing profitability. These should be reestablished as the hospitals that can provide public health care services while ensuring stable profitability.