• Korean Journal of Veterinary Research
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• v.37 no.2
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• pp.301-310
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• 1997

Diabetes mellitus is associated with a wide range of pathophysiological in the kidney. This study was designed to examine the effects of high glucose concentration on IGF-I binding and glucose transporters in renal proximal tubule cells. The results were as follows : The binding of $^{125}I-IGF-I$ reached the peak at the 30 minutes and gradually decreased by the time dependent manner. The binding of $^{125}I-IGF-I$ was inhibited by the unlabelled IGF-I($10^{-14}{\sim}10^{-8}M$) in a concentration dependent manner. The relative affinity of IGF-I receptor for IGF-I, IGF-II and insulin exhibited typical type 1 binding(IGF-I > insulin > IGF-II). However IGF-II did not compete for the cultured cell membrane $^{125}I-IGF-I$ binding site at $10^{-14}{\sim}10^{-8}M$. Under optimal conditions, IGF-I binding to the membranes from 5mM and 20mM glucose treated cells was analyzed. It was found that 20mM glucose treated cells exhibited higher binding activity for IGF-I. In order to further substantiate this increase in IGF-I binding sites, we performed affinity-labelling studies. The cross-linked cell membrane subjected to SDS-PAGE; labelled material was detected by autoradiography. 20mM glucose treated cells exhibited higher levels. The initial rate of $methyl-{\alpha}-D-glucopyranoside({\alpha}-MG)$ uptake was significantly lower($74.41{\pm}6.71%$) in monolayers treated with 20mM glucose than those of 5mM glucose. However, 3-O-methyl-D-glucose(3-O-MG) uptake was not affected by glucose concentration in culture media. IGF-I significantly increased ${\alpha}-MG$ uptake in both 5mM and 20mM glucose treated cells. However, 3-O-MG uptake was not affected by IGF-I in both conditions. In conclusion, 20mM glucose increased binding sites of $^{125}I-IGF-I$, inhibited Na/glucose cotransporter activity. But 20mM glucose did not change facilitated glucose transporter.

• The Journal of the Korea Contents Association
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• v.14 no.4
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• pp.37-46
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• 2014

Industrialization and urbanization have led automobiles to transform into more than just modes of transportation; they have become daily necessities as well as extensions of living spaces where a variety of activities can be done and automotive applications of the latest information technology are accelerated. Though material abundance has increased in the modern society, the conflicts and the stress emerging from a social structure focused on competition have increased as well. Such lifestyles generate a need for personal space and media content for healing the body and the mind. This research explores the automotive application of video content with the goal of refreshing the minds of the passengers. To this end, previous studies have investigated the emotional effect of videos, focusing on the responses of diverse groups of adults (age group of 20 to 60) who frequently used automobiles, which had video displays installed in them. The results showed that watching video contents on a full window inside a car influenced the creation of positive feelings7 and emotional satisfaction. The research attempts to study the methods of providing video contents and the effects of watching them that could aid the emotional well-being of passengers, and presents the possibility of emotional satisfaction created by a convergence of cars and multimedia contents in the future.

• Journal of Wetlands Research
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• v.14 no.1
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• pp.75-87
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• 2012

Hyporheic zone is a region beneath and alongside a stream, river, or lake bed, where there is mixing of shallow groundwater and surfacewater. Hyporheic exchange controls a variety of physical, biogeochemical and thermal processes, and provides unique ecotones in a aquatic ecosystem. Field and experimental observations, and modeling studies indicate that hyporheic exchange is mainly in response to pressure gradients driven by the geomorphological features of stream beds. In the reach scale of a stream, pool-riffle structures dominate the exchange patterns. Flow over a pool-riffle sequence develops recirculation zones and stagnation points, and this flow structures make irregular pressure gradient which is driving force of the hyporheic exchange. In this study, 3 D hydro-dynamic model solves the Reynolds-averaged Navier-Stokes equations for the surface water and Darcy's Law and the continuity equation for ground water. The two sets of equations are coupled via the pressure distribution along the interface. Simulation results show that recirculation zones and stagnation points in the pool-riffle structures dominantly control the upwelling and downwelling patterns. With decrease of recirculation zones, length of donwelling zone formed in front of riffles is reduced and position of maximum downwelling point moves downward. The numerical simulation could successfully predict the behavior of hyporheic exchange and contribute the field study, river management and restoration.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.11 no.1
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• pp.153-166
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• 1991

In an attempt to investigate the effect of intermedate principal stresses which are related to the stress-strain behavior of standard sands, a series of three-Principal stress control tests were conducted for individual stress paths. The results have shown that shear strengths of sands vary with the stress paths. The variations in internal friction angle are accorded with the Habibs stress parameter, b which represents Stress paths, showing on abropt increase at the values between 0.0 and 0.268, a moderate level between 0.268 and 0.682, and a slight decrease between 0.682 and 1.0 However, the friction angles under a triaxial extention state, were found relatively larger than under a triaxial compression state. In general, such veriations were found to have the same tendency without any relevant relation with the density of specimens and confining pressures. Therefore, it is concluded, that the shear strength of sands are positively influeced by the intermediate principal stresses present in the media. And the influnce of intermediate principal stresses on shear strengths of sands found from the present study are well compared with the previous studies by Lade-Duncan and Matsuoka-Nakai revealing a similar tendency within the failure criteria proposed by them.

• Fashion & Textile Research Journal
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• v.14 no.4
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• pp.614-628
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• 2012

The purpose of this study was to analyze research trends and make suggestions regarding the future of information technology (IT) in the fashion industry. In this study, 437 papers written regarding IT fashion from five major journals published between 2000 and 2011 were examined. The research areas were then organized by subject and keyword, and divided into 16 high-context categories. Two IT fashion maps were constructed, one from a fashion consumer's perspective, and the other based on the fashion industry's supply chain. This study identified important trends in IT fashion such as: 3D scanners, 3D digital renderings of the human form, 3D digital garments, smart garments, mass customization, production automation, online shopping, home shopping, online communities, e-commerce, digital media, virtual reality, e-tail, the digital generation, E-CRM, and education. Data from body scans was collected and applied to production, and research on smart textiles was also carried out. As for IT fashion's service areas, the majority of the research focused on online shopping or online communication. Additionally, research done on avatars and cyber space, and studies on social networking services are shown. The results of this study indicated that a new field of research has opened and that current research has been developing. Also, this study showed what is needed to expand and strengthen IT fashion.

• Korean journal of applied entomology
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• v.16 no.1 s.30
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• pp.47-53
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• 1977

Bacterial diseases of soybean has been recognized as a limiting factor of soybean production in Korea as it was estimated to cause around 10 percent of yield losses annually. The purpose of the study is to obtain information on the diseases through proving the kinds of pathogens and epidemiology, The wire brush method and multineedle appeared to be the best way of inoculation under all circumstances. Wire brush method, especially, was effective in shortening the incubation period and manifesting the lesion development by introducing more inoculum per unit of area. In case of spray inoculation it was necessary to apply a small amount(1 : 1,000) of wetting agent, twin-20, otherwise it was unabled to produce the diseases under field conditions. Two kinds of bacterial diseases caused by Pseudomonas glycinea and Xanthomonas phaseoli var. sljense were found from surveyed areas in Kore. Wild fire disease on soybean caused by Pseudomonas tabaci had not detectable during the experiment although there were several reports on the disease from other countries. when the pathogens were introduced into sterile soil, bacterial leaf blight pathogen could exsisted until 30 days while bacterial pustule pathogen survived only 4 days under the natural conditions of later June. Both bacteria, however, could produce the disease after more than 10 months period of storage in refrigerator when they were exsisted in infected plant tissues. In warehouse, non-temperature controlled, the bacteria lose their infectability within 6 months period from October to April even though they exsisted in infected tissues. Surface infested seeds with the pathogens could not produced the diseases on seedling stages of soybean plants when the seeds were planted in sterile soil after inoculation by dipping the seeds into bacterial suspensions, although germination was depressed by the pathogens when the seeds were planted on agar media.

• Journal of the Ergonomics Society of Korea
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• v.35 no.4
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• pp.205-223
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• 2016

Objective:This study introduced the status of studies and the projects related with agricultural accident prevention carried out by the Rural Development Administration. This study was conducted to promote Korean farmers' agricultural safety activation by analyzing study trends on farmers' agricultural work safety. Background: Agriculture is one of the dangerous industries, and the agricultural accident rate is on the rise, due to recent serious aging and increased female work force. Such a phenomenon emerges as a serious problem from the social perspective, and therefore measures for farmers' healthy and safe agricultural activities and accident prevention are required. Method: This study conducted literature review related with domestic and international agricultural safety and health. This study also examined the hazard factors of agricultural labor and injuries, agricultural safety and health system and policy, support and education for farmers' safety practice, and the status of convenience tools and protection equipment, based on major study activities performed by the Rural Development Administration for recent four to five years. Results: Through the study results, the status of Korea's agricultural safety system, compensation support policy, safety education of farmers for actual practice, and diverse channels including media were confirmed. This study also presented the R&D implementation status on convenience equipment and protective gear to prevent agricultural diseases and safety accidents. Conclusion: This study found out that continuous monitoring and efforts are required to prevent accidents for the Korea's agricultural labor environment and agricultural safety, and that social bond of sympathy formation is demanded through effect analysis on the implemented projects including education and support projects. Furthermore, it can be understood that agricultural accident prevention should be carried out through shift from current government-led top down approach to bottom-up approach from itself. Application: The results of this study can be utilized as useful data for farmers' safety and health.

• Korean Journal of Child Education & Care
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• v.18 no.3
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• pp.65-75
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• 2018

Objective: The purpose of this study is to find out the perception on childe abuse of pre-service childcare teachers who will become the closest witnesses to child abuse, and also whether they have the proper knowledge and attitude to report abuse. Methods: Surveys were conducted at five universities in Seoul and Kyonggi-province. We investigated students from child development major, and additionally students from other majors as a comparative group. Results: The results of this study are as follows: First, pre-service childcare teachers' level of abuse severity was significantly higher than other major students. They were more aware of child abuse reporting system and reporting obligations than other major students. Second, pre-service teachers had higher intention of reporting then other major students. However, both groups barely know about child protection institution, and have negative perception on the effect of reporting. Conclusion/Implications: In conclusion, this study suggests that pre-service teachers are more aware of child abuse and willing to report than other major students, however it is necessary to increase the reliability of report effectiveness. Also, it provide implications for future policy-making related to child abuse by suggesting that information transmission and promotion through mass media is necessary and efforts should be made to reduce the risk of disclosure of the identity of the complainant in reporting abuse.

• Journal of the Korea Society of Computer and Information
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• v.25 no.9
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• pp.203-212
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• 2020

The purpose of this study is to analyze the perception of non-face-to-face online undergraduate lectures experienced by foreign learners, to identify problems of online lectures, and to suggest improvements. For this study, the perception of online lectures was investigated and analyzed by foreign undergraduate students who took online lectures at A and B universities. Through this, I explored the design direction, complementary measures, and direction of online lectures to be held at Korean universities in the future. As a result of this study, non-real-time lectures through E campus were recognized as advantages in that they could learn repeatedly and listen to lectures at home., Real-time lectures using Zoom were recognized as an advantage of being able to communicate between professors and learners. Both types of online lectures had many tasks and had difficulty in focusing on the lecture until the end. In the future, it was found that the amount of lecture contents and the amount of tasks should be reduced and the condition and sound quality of the lecture image should be improved. As for the evaluation method, they preferred online evaluation rather than offline evaluation, and they preferred relative evaluation rather than absolute evaluation. The results of this study were able to closely understand how learners perceive online lectures. Also, when conducting online lectures, I was able to know the points that need to be improved in the future. The results of this study are expected to contribute to the design direction of online lectures and the development of online contents at each university.

• IMMUNE NETWORK
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• v.1 no.2
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• pp.170-178
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• 2001

Background: Korean mistletoe (Viscum album) extract has been found to posses immunostimulatory activity. In this study, Korean mistletoe extract, M11C (non-lectin components), was used to know whether this extract might activate mouse peritoneal macrophages to produce interleukin $1{\beta}$ (IL-$1{\beta}$). Methods: Hemagglutination assay was carried out to examine whether M11C contained a lectin or not. To know the effect of M11C on the production of IL-$1{\beta}$, the macrophages were treated by the M11C, and then collected the supernatant (M11C stimulated macrophages-conditioned media; MMCM). MMCM was analyzed for the IL-$1{\beta}$ quantification and mRNA expression by means of ELISA and RT-PCR, respectively. Results: Maximum effective dose and time of M11C on IL-$1{\beta}$ production from macrophages were $20{\mu}g/m{\ell}$ and 8 hours, respectively. This ELISA data was reconfirmed by immunoblotting assay. indicating that M11C is a good candidate for an immunomodulator. The dose and time dependent effects of M11C on the expression of IL-$1{\beta}$ mRNA from macrophages was also shown in expression of mRNA detected by RT-PCR. Treatment dose and time for the maximum expression of IL-$1{\beta}$ mRNA were $20{\mu}g/m{\ell}$ and 4 hours, respectively. Maximum gene expression of IL-$1{\beta}$ was much earlier than maximum production of it. Conclusion: As results, Korean mistletoe extract, M11C, may be used for an immunomodulator. This will be able to make up for and solve the problems caused by existent immunoagent with many adverse effects through many other studies in future including one molecule extraction.