• Title/Summary/Keyword: Mechanical Index

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The Effects of Dokhwalgisaeng-tang(Duhuoqisheng-tang ) and Jungsongouhyul Pharmacopuncture on Pain Control and Nerve Regeneration in the Crush-induced Sciatic Nerve Injury of the Rat Model (독활기생탕(獨活寄生湯) 및 중성어혈약침(中性瘀血藥鍼)이 좌골신경 압좌손상 백서의 통증과 신경 재생에 미치는 영향)

  • Lee, Sang-Gyu;Won, Jae-Kyun;Yeom, Seung-Ryong;Lee, Su-Kyung;Song, Yung-Sun;Kwon, Young-Dal
    • Journal of Korean Medicine Rehabilitation
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    • v.19 no.3
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    • pp.15-32
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    • 2009
  • Objectives : The purpose of this Study was to identify the effect of Dokhwalgisaeng-tang(Duhuoqisheng-tang) and Jungsongouhyul pharmacopuncture on pain control and nerve regeneration after crush injury in rat sciatic nerve. Methods : Neuropathic pain was induced by crush-induced model of right sciatic nerve. Animal groups were divided as follows; Group I: no treatment control group, Group II : experimental group treated with Dokhwalgisaeng-tang(Duhuoqisheng-tang), Group III : experimental group treated with Jungsongouhyul pharmacopuncture, and Group IV : experimental group treated with Dokhwalgisaeng-tang(Duhuoqisheng-tang) and Jungsongouhyul pharmacopuncture. To evaluate pain intensity, each group was observed paw withdrawal threshold and immunoreactivity on the c-fos before and after respective treatments in five hours, first, third, and fifth day. To evaluate nerve regeneration, those were observed SFI(Sciatic Functional Index) and GAP-43(Growth Associated Protein 43) after each treatment in seventh and thirteenth day. Results : 1. Paw withdrawal threshold to the mechanical stimuli made the significant difference between group IV and the control group after five days of the experiment. 2. Paw withdrawal threshold to the thermal stimuli made the significant difference between group I and III, I and IV, II and IV. 3. In immunohistochemical response of c-fos, as time passes, the immunoreactivity of all groups was decreased gradually. Especially, group IV was observed the lowest after three days. 4. The differences of sciatic function indexes in each group were significantly between group I and III, I and IV, II and IV after 14 days, and between group I and III, I and IV, II and IV, III and IV after 21 days. 5. In immunohistochemical response of GAP-43, all groups had higher GAP-43 immunoreactivity at the 14 days from post-injury and group IV showed highest immunoreactivity. Conclusions : Based on above the results, it is proposed that Dokhwalgisaeng-tang(Duhuoqisheng-tang) and Jungsongouhyul pharmacopuncture may be helpful as a treatment in neuropathic pain and nerve regeneration in rat model.

Preparation and Characterization of Anti-reflective and Anti-static Double Layered Films by Sol-Gel Spin-Coating Method (졸-겔 스핀코팅법에 의한 반사방지 및 정전기방지 복층막의 제조 및 특성)

  • 이준종;최세영
    • Journal of the Korean Ceramic Society
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    • v.34 no.1
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    • pp.79-87
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    • 1997
  • Anti-reflective and anti-static double layered films were prepared on the VDT panel by sol-gel spin-coating method. Their electrical, opticla, and mechanical properties were investigated. The outer SiO2 film with low re-fractive index was coated over the inner ATO(Antimony-doped Tin Oxide)-SiO2 film which was prepared by mixing ATO sol with SiO2 at molar ratio of 68:32 to satisfy the interference condition of double layers. The heat treatment was conducted at 45$0^{\circ}C$ for 30 min where residual organics were completely removed. The sheet resistance of ATO single layer showed the minimum value of 6$\times$107$\Omega$/$\square$ at 3 mol% addition of Sb and that of SiO2/ATO-SiO2 increased slightly with increasing SiO2 mol% up to 30 mol%, and then increased steeply to the value of 3$\times$108$\Omega$/$\square$ at 32 mol%. The reflectance of double layered films was about 0.64% at the wavelength of 550nm and the transmittance increased about 3.20%. The hardness of double layered films was almost the same as that of uncoated VDT panel, 471.4kg.f/mm2.

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A Review of the Assessment Tools in Clinical Trials for Patients Injured in Traffic Accidents in South Korea (국내 교통사고 후유증 환자의 평가도구에 대한 임상연구 실태조사)

  • Jo, Hee Jin;Kwon, Min Soo;Kim, Jung Hwan;Jo, Dae Hyun;Choi, Ji Eun;Han, Ji Sun;Lee, Seung Min;Lee, Sang Hoon;Nam, Sang Soo
    • Journal of Acupuncture Research
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    • v.33 no.4
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    • pp.15-31
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    • 2016
  • Objectives : The aim of this study is to review the instruments used to assess patient condition and the effects of Korean medical treatment for patients injured in traffic accidents in clinical studies in the Korean medical field published in South Korea. Methods : A literature study was performed, and clinical studies on patients injured in traffic accidents visiting Korean medical clinics or hospitals were examined. Data about chief complaints, tools used to assess either patients' condition or the effectiveness of Korean medical treatment, and time point of assessment were extracted. The studies were classified according to symptom. The use-frequency and the parent category of the assessment tools were also analyzed. Results : 78 studies were selected and classified into 5 categories based on the chief complaints, neck pain, lower back pain, headache, psychological symptoms and unspecified symptoms. Various scales were used to report the patient's pain severity, and functional or psychological status resulting from traffic accidents. Pain index, in particular VAS, was most frequently used and a few mechanical instruments and Korean medicinal assessment tools were mentioned. Conclusion : Most instruments used in Korean medicine clinical studies on patients injured in traffic accidents are self-reported tools. To assess both the patient's condition precisely and the effectiveness of Korean medical treatment on patients injured in traffic accidents, more appropriate and unified tools should be designed that consider pain, functional disability, psychological status and objective assessments measured by devices together.

Synthesis and Characterization of Novel Polythiourethanes (새로운 폴리(티오우레탄)의 합성 및 특성)

  • 김경만;허영태;박인환;이범재
    • Polymer(Korea)
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    • v.27 no.5
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    • pp.470-476
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    • 2003
  • In order to obtain high refractive plastic materials, 1,2 -ethylenedisulfanylbis(2-mercaptomethyl-1-ethanthiol) (ESTT) was newly prepared in good yield by the reaction of 1,2-ethylenedisulfanylbis(2-bromomethyl-1-ethanthiol) (ESTB) with thiourea followed by hydrolysis using an aqueous ammonia solution and characterized by $^1$H-NMR (-SH at 1.7 ppm), $\^$13/C-NMR(-CH$_2$SH at 28.4 ppm) and FT-IR (-SH at 2540 cm$\^$-1/) spectroscopy, etc. Polythiourethanes (PTU) were obtained from the combinations of ESTT with each of 4,4'-methylenebis(phenylisocyanate) (MDI), tolyene 2,4-diisocyanate (TDI), isophorone diisocyanate (IPDI), mxylene diisocyanate (XDI), and 1,6-diisocyanatohexane (HMDI) in the presence of dibutyltin dilaurylate as a catalyst, in a casting mold, and characterized by FT-IR (existence of N=C=O) spectroscopy and elemental analyzer (sulfur content). Accordingly, their thermal, mechanical and optical properties were investigated by using DSC, TGA, hardness tester and refractometer: both the melting point on DSC and crystallinity on X -ray diffraction (XRD) for specimens of PTUs were not observed. PTUs with T$\_$g/s above 110 $^{\circ}C$ showed good hardness (Shore D) in the range of 86 to 89. Thermal stabilities of PTUs obtained by using ESTT and each of diisocyanates containing aromatic rings were especially good. Also, the optical transmittances of amorphous PTUs through UV-visible source in the range of 400 to 600 nm were good. PTUs showed refractive indexes above 1.60, and their refractive indexes gradually increased with increase of sulfur contents.

Modeling on Rheological Behavior of Cement Paste under Squeeze Flow (압축 유동하에 있는 시멘트 페이스트의 유변학적 거동에 관한 모델링)

  • Min, Byeong-Hyeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.9
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    • pp.405-413
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    • 2020
  • The normal stress of cement paste measured under squeeze flow is divided into an elastic solid region at strains between 0.0003 and 0.003 and a strain-hardening region at strains of 0.003 and 0.8. A modeling equation at the strain-hardening region was proposed. First, from the viewpoint of fluid behavior, the power-law non-Newtonian fluid model, with a power-law consistency (m) of 700 and a power index (n) of 0.2, was applied. The results showed good agreement with the experimental results except for an elastic solid region. Second, from the viewpoint of ductile yielding solid behavior, the force balance model was applied, and the friction coefficient between the sensor part measuring the load and the surface of the cement paste was derived as a polynomial of the normal strain by applying the half-interval search method to the experimental data. The results showed good agreement with the experimental results only in the middle normal strain region at strains between 0.003 and 0.3. The rheological behavior of the cement paste under squeeze flow was more consistent with the experimental results from the viewpoint of power-law non-Newtonian fluid behavior than from the viewpoint of ductile yielding solid behavior in the strain-hardening region.

Development of Yeast Leavened Pan Bread Using Commercial Doenjangs (Korean Soybean Pastes): 1. Physicochemical Properties of Doenjang and Physical Properties of Bread Added with Doenjang (시판 된장을 이용한 식빵 제조: 1. 된장의 이화학적 특성 및 된장을 첨가한 식빵의 물리적 특성)

  • 오현주;문혜경;김창순
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.7
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    • pp.1002-1010
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    • 2003
  • This study was carried out to develope yeast leavened pan bread using the commercial Doenjangs (Korean soybean pastes). Physicochemical properties of the Doenjang products were measured such as aminonitrogen, pH, titratable acidity and salinity, reducing sugar, total free sugar, total organic acid, PDI (protein dispersibility index) and color. Seven products of Doenjang were freeze-dried and powdered to be used in bread formula at the levels of 2.5, 5.0, 7.5 and 10.0%. When the Doenjang powder was added up to 5.0%, the ovenspring during baking remarkably increased resulting in increased loaf volume. However, with Doenjang powder more than 7.5%, the loaf volume became smaller than the control as the dough expansion and ovenspring decreased. Thus when Doenjang was added to bread dough, the loaf volume was highly correlated with ovenspring (r=0.92) but it was not with dough expansion during 1st fermentation (r=0.56). The browning color of bread crust and crumb became deeper with decrease in L value as the addition of Doenjang powder increased. From the mechanical texture measurements of bread crumb, hardness, gumminess and chewiness decreased with addition of Doenjang powders. Regardless of the kinds of Doenjang, the Doenjang powders could be added into the bread dough up to 5.0%, improving the loaf volume and texture of yeast leavened pan bread and demonstrating the possibility of producing a functional bread using the Doenjang powders.

Clinical Results of Different Myocardial Protection Techniques in Aortic Stenosis

  • Lee, Jung Hee;Jeong, Dong Seop;Sung, Kiick;Kim, Wook Sung;Lee, Young Tak;Park, Pyo Won
    • Journal of Chest Surgery
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    • v.48 no.3
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    • pp.164-173
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    • 2015
  • Background: Hypertrophied myocardium is especially vulnerable to ischemic injury. This study aimed to compare the early and late clinical outcomes of three different methods of myocardial protection in patients with aortic stenosis. Methods: This retrospective study included 225 consecutive patients (mean age, 65{\pm}10 years; 123 males) with severe aortic stenosis who underwent aortic valve replacement. Patients were excluded if they had coronary artery disease, an ejection fraction <50%, more than mild aortic regurgitation, or endocarditis. The patients were divided into three groups: group A, which was treated with antegrade and retrograde cold blood cardioplegia; group B, which was treated with antegrade crystalloid cardioplegia using histidine-tryptophan-ketoglutarate (HTK) solution; and group C, treated with retrograde cold blood cardioplegia. Results: Group A contained 70 patients (31.1%), group B contained 74 patients (32.9%), and group C contained 81 patients (36%). The three groups showed significant differences with regard to the proportion of patients with a New York Heart Association functional classification ${\geq}III$ (p=0.035), N-terminal pro-brain natriuretic peptide levels (p=0.042), ejection fraction (p=0.035), left ventricular dimensions (p<0.001), left ventricular mass index (p<0.001), and right ventricular systolic pressure (p <0.001). Differences in cardiopulmonary bypass time (p=0.532) and aortic cross-clamp time (p=0.48) among the three groups were not statistically significant. During postoperative recovery, no significant differences were found regarding the use of inotropes (p=0.328), mechanical support (n=0), arrhythmias (atrial fibrillation, p=0.347; non-sustained ventricular tachycardia, p=0.1), and ventilator support time (p=0.162). No operative mortality occurred. Similarly, no significant differences were found in long-term outcomes. Conclusion: Although the three groups showed some significant differences with regard to patient characteristics, both antegrade crystalloid cardioplegia with HTK solution and retrograde cold blood cardioplegia led to early and late clinical results similar to those achieved with combined antegrade and retrograde cold blood cardioplegia.

Product Characteristics as Factors of Process Parameters in Starch Phosphates Preparation by Twin-screw Extruder (이축압출성형기로 인산전분 제조시 Process Parameters에 따른 제품의 특성)

  • Kim, Chong-Tai;Kim, Dong-Chul;Kim, Chul-Jin;Kim, Hae-Sung
    • Korean Journal of Food Science and Technology
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    • v.23 no.2
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    • pp.235-240
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    • 1991
  • Starch phosphates were prepared from the corn starch mixed with 2% sodium tripolyphosphate by twin-screw extruder with a feed rate of 20 kg/hr and an extrusion temperature of $130^{\circ}C$, and the effects of extrusion variables on the physicochemical properties (target parameters) of starch phosphates were investigated. Interrelations of system parameters (specific mechanical energy and extrudate moisture) and rheological properities of starch was analyzed by using the response surface analysis. Degree of substitution (DS) was increased with increasing the feed moisture, and showed the maximum value at the screw of near 250 rpm, Degree of gelatinization was proportionally increased with increasing the screw speed and decreasing the feed moisture. Apparent viscosity of the paste was increased with increasing the feed moisture, but it was not significantly affected by the screw speed. It was found by scanning electron microscopy that the starch microgranules were much more degradaded, and as consequent result, the intrinsic viscosity was decreased, whereas, water solubility index was increased. The rate of retrogradation of the gels was retarded with increasing DS and decreasing viscosity.

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Comforts Evaluation of Car Seat Clothing (자동차 시트 표피재의 감성평가)

  • Kim, Joo-Yong;Lee, Chae-Jung;Kim, An-Na;Lee, Chang-Hwan
    • Science of Emotion and Sensibility
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    • v.12 no.1
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    • pp.77-86
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    • 2009
  • A comfort evaluation of car seat clothing has been proposed for high comforts interior seat clothing. Car seat covers have received wide spread attention due to their man-machine interface working. And then, it will be necessary for measurements on delicate basic mechanical-properties, which closely relate with human touch feeling of its materials. In this research, we have utilized $KES-FB^{(R)}$(Kawabata Evaluation System) series, $^ST300{(R)}$ analogue softness tester and friction tester for measurement a physical properties. In order to consider both kansei and physical properties on interior seat covers, we firstly have established subjective words of judgement for the seat covers. Secondly, related them to the objective measurement of physical properties. Each kansei-language has clearly defined as 'Softness', 'Elasticity', 'Volume' and 'Stickiness' for the adjectives of leather car seat covers. These technical terms have correlated to physical properties in other words, h (mm), bending moment ($gf^*$cm/cm), To-Tm (mm) and ${\mu}$. At this time, fuzzy logic has utilized to predict the value of kansei language through physical values. On the basis of this result, finally it is possible to predict quality index of car seat covers using neural networks technique. In short, we develop a quality evaluation system of car seat clothing combining four physical quantities with kansei engineering.

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Effect of Gums on the Characteristics of the Dough in Making Frozen Dough (냉동생지 제조시 검류의 첨가가 반죽특성에 미치는 영향)

  • Lee, Jong-Min;Lee, Myung-Ku;Lee, Si-Kyung;Cho, Nam-Ji;Cha, Wook-Jin;Park, Jung-Kil
    • Korean Journal of Food Science and Technology
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    • v.32 no.3
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    • pp.604-609
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    • 2000
  • This study was carried out to investigate the possibilities of adopting xanthangum, guargum and ${\kappa}-carrageenan$ as cryprotectant by examining the rheological and structural properties of dough. Results of farinography showed that water absorption, development time and mechanical tolerance index in dough with the gums increased more than those of the control. It was also found that resistance in dough with the gums increased greatly, but extensibilities were similar to that of the control, resulting in increasing R/E values in the dough with the gums through extensograph. According to amylogram, gelatinization temperature of dough was $59.5^{circ}C$ and those of the dough with the gums were $58^{circ}C$. Even though maximum viscosity of the dough was 550 B.U in the control, those were 690 B.U, 780 B.U and 760 B.U in the dough with xanthangum, guargum, and ${\kappa}-carrageenan$, respectively. The control deeply increased the pH during frozen storage but the addition of ${\kappa}-carrageenan$ and xanthangum increased the pH slightly. The dough with the gums had more stable spaces than control in the microstructure through SEM.

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