• Journal of Navigation and Port Research
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• v.34 no.3
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• pp.175-180
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• 2010

In the almost application parts, GNSS being used the primary navigation system on world-widely. However, some of nations attempt or deliberate to enhance current Loran system, as a backup to satellite navigation system because of the vulnerability to the disturbance signal. Loran interests in supplemental navigation system by the development and enhancement, which is called eLoran, and that consists of advancement of receiver and transmitter and of differential Loran in order to increase the accuracy of current Loran-C. A significant factor limiting the ranging accuracy of the eLoran signal is the ASF in the TOAs observed by the receiver. The ASF is mostly due to the fact that the ground-wave signal is likely to propagate over paths of varying conductivity and topography. This paper presents comparison results between the predicted ASF and the measured ASF in a southern east region of Korea. For predicting ASF, the Monteath model is used. Actual ASF is measured from the legacy Loran signal transmitted Pohang station in the GRI 9930 chain. The test results showed the repeatability of the measured ASF and the consistent characteristics between the predicted and the measured ASF values.

• Journal of Navigation and Port Research
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• v.37 no.4
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• pp.375-381
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• 2013

In order to establish eLoran system it needs the betterment of a receiver and a transmitter, the add of data channel to loran pulse for loran system information and the differential Loran for compensating Loran-c signal. Precise ASF database map is essential if the Loran delivers the high absolute accuracy of navigation demanded at maritime harbor entrance. In this study we developed the ASF mapping method using predicted ASFs compensated by the measured ASFs for maritime in the harbor. Actual ASF is measured by the legacy Loran signal transmitted from Pohang station in the GRI 9930 chain. We measured absolute propagation delay between the Pohang transmitting station and the measurement points by comparing with the cesium clock for the calculation of the ASFs. Monteath model was used for the irregular terrain along the propagation path in the Yeongil Bay. We measured the actual ASFs at the 12 measurement points over the Yeongil Bay. In our ASF-mapping method we estimated that the each offsets between the predicted and the measured ASFs at the 12 spaced points in the Yeongil. We obtained the ASF map by adjusting the predicted ASF results to fit the measured ASFs over Yeungil bay.

• Journal of Navigation and Port Research
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• v.35 no.8
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• pp.619-624
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• 2011

A significant factor limiting the ranging accuracy of Loran (Long Range Navigation) signal is the additional secondary factor (ASF) in the time of arrival (TOA) measurements. Precise ASF values are essential if Loran deliver the high absolute accuracies demanded for aircraft approach, maritime harbour entrance. We measured the absolute propagation delay between Pohang Loran signal and Loran receiver output signal by comparing with Cesium atomic clock. In this study we measured ASFs between Pohang 9930M station and the 12 measurement points in the Yeongil Bay by using the measurement technique of absolute time delay. The measurement points were spaced at interval of 3 km by 3 km. An E-field antenna and an H-field antenna were used to improve the accuracy of ASF measurements and a DGPS (Differential GPS) receiver was used for accurate positions. We have gotten the result that the measured ASFs were compared with the predicted ASFs through this measurement technique.

• Journal of Navigation and Port Research
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• v.40 no.1
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• pp.15-20
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• 2016

In this study we measured a differential ASF to improve the accuracy of time synchronization with the signal transmitted from Pohang 9930M Loran station. We obtained the differential ASF which is calculated from a difference of the TOA measurements between KRISS and Chungnam National University(CNU), and KRISS and National Maritime PNT Office respectively. The TOA measurement at KRISS was measured by UTC(KRIS) reference clock and other sites were measured by atomic clocks respectively. The time variations of differential ASF measurements at CNU and National Maritime PNT Office were within $0.1{\mu}s$ and $0.05{\mu}s$ respectively. And we found the time variations of $0.1{\mu}s$ depending on the surrounding radio-wave environments from the differential ASF measurements of 60 minute moving averages. We can improve the accuracy of time synchronization of the local clock to within 10 ns by compensating the differential ASF through removing the common component of ASF. And we measured the absolute ASF between the Pohang transmit station and KRISS by the measurement technique of absolute time delay using a cesium atomic clock. The average ASF between two points is about $3.5{\mu}s$.

• Journal of Positioning, Navigation, and Timing
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• v.2 no.2
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• pp.109-114
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• 2013

The vulnerability of GPS to interference signals was reported in the early 2000s, and an eLORAN system has been suggested as a backup navigation system for replacing the existing GPS. Thus, relevant studies have been carried out in the United States, Europe, Korea, etc., and especially, in Korea, the research and development is being conducted for the FOC of the eLORAN system by 2018. The required performance of the eLORAN system is to meet the HEA performance, and to achieve this, it is essential to perform ASF correction based on a dLORAN system. ASF can be divided into temporal ASF, nominal ASF, and spatial ASF. Spatial ASF is the variation due to spatial characteristics, and is stored in an eLORAN receiver in the form of a premeasured map. Temporal ASF is the variations due to temporal characteristics, and are transmitted from a dLORAN site to a receiver via LDC. Unlike nominal ASF that is obtained by long-term measurement (over 1 year), temporal ASF changes in a short period of time, and ideally, real-time correction needs to be performed. However, it is difficult to perform real-time correction due to the limit of the transmission rate of the LDC for transmitting correction values. In this paper, to determine temporal ASF correction frequency that shows satisfactory performance within the range of the limit of data transmission rates, relative variations of temporal ASF in summer and winter were measured, and the stability of correction values was analyzed using the average of temporal ASF for a certain period.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.11
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• pp.1776-1788
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• 2019

Objective: The demands for measures to improve disease resistance and productivity of livestock are increasing, as most countries prohibit the addition of antibiotics to feed. This study therefore aimed to uncover functional feed additives to help enhance livestock immunity and disease resistance, using Acanthopanax sessiliflorus fruit extract (ASF). Methods: ASF was extracted with 70% EtOH, and total polyphenolic and catechin contents were measured by the Folin-Ciocalteu and vanillin assay, respectively. The 3D4/31 porcine macrophage cells ($M{\Phi}$) were activated by phorbol 12-myristate 13-acetate (PMA), and cell survival and growth rate were measured with or without ASF treatment. Flow-cytometric analysis determined the lysosomal activity, reactive oxygen species levels (ROS), and cell cycle distribution. Nuclear factor kappa B ($NF-{\kappa}B$) and superoxide dismutase (SOD) protein expression levels were quantified by western blotting and densitometry analysis. Quantitative polymerase chain reaction was applied to measure the lipid metabolism-related genes expression level. Lastly, the antibacterial activity of 3D4/31 $M{\Phi}$ cells was evaluated by the colony forming unit assay. Results: ASF upregulated the cell viability and growth rate of 3D4/31 $M{\Phi}$, with or without PMA activation. Moreover, lysosomal activity and intracellular ROS levels were increased after ASF exposure. In addition, the antioxidant enzyme SOD2 expression levels were proportionately increased with ROS levels. Both ASF and PMA treatment resulted in upregulation of $NF-{\kappa}B$ protein, tumor necrosis factor $(TNF){\alpha}$ mRNA expression levels, lipid synthesis, and fatty acid oxidation metabolism. Interestingly, co-treatment of ASF with PMA resulted in recovery of $NF-{\kappa}B$, $TNF{\alpha}$, and lipid metabolism levels. Finally, ASF pretreatment enhanced the in vitro bactericidal activity of 3D4/31 $M{\Phi}$ against Escherichia coli. Conclusion: This study provides a novel insight into the regulation of $NF-{\kappa}B$ activity and lipid metabolism in $M{\Phi}$, and we anticipate that ASF has the potential to be effective as a feed additive to enhance livestock immunity.

• Journal of the Institute of Convergence Signal Processing
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• v.12 no.2
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• pp.107-112
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• 2011

Several developed countries have been developing their own satellite navigation systems, such as Europe's Galileo, China's BEIDOU, and Japan's QZSS, to cope with clock errors and signal vulnerabilities of GPS. In addition, modernization of Loran, eLoran, for GPS backup has been conducted. In Korea, a dependent navigation system has been required and for GPS backup, the need for utilization of time synchronization infrastructure through the modernization of Loran has been raised. Loran signal uses 100Khz groundwave. A significant factor limiting the ranging accuracy of the Loran signal is the ASF arising from the fact that the groundwave signal is likely to propagate over paths of varying conductivity and topography. Thus, an ASF compensation method is very important for Loran and eLoran navigation. This paper introduces the propagation delay model and then compares and analyzes the estimations from the propagation delay model and measured ASFs.

• Journal of dental hygiene science
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• v.18 no.3
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• pp.147-154
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• 2018

This study aimed to evaluate the antimicrobial effects of Acanthopanax sessiliflorum fruit (ASF; Ogaza) extracts on Streptococcus mutans and Streptococcus sobrinus, which are agents that cause dental caries, and on Streptococcus mitis and Streptococcus salivarius, the microbial flora of the oral cavity. The ASF extracts obtained using 70% ethanol were fractionated in the order of ethyl acetate and n-Butanol, concentrated under reduced pressure, and lyophilized to give powdery solvent extracts. The antimicrobial activity of ASF extracts from each solvent was examined using the disk diffusion method. As a result, only those extracts obtained using an ethyl acetate solvent showed antimicrobial activity. These extracts were selected, and the minimum inhibitory concentration was measured by disk diffusion method at various extract concentrations. Results showed a minimum inhibitory concentration of 32 mg/ml. The viable cell count was measured to confirm the minimum bactericidal concentration. Results showed a minimum bactericidal concentration of 64 mg/ml. In the cytotoxicity test using normal human dermal fibroblast cells, the absorbance value of the test group was similar to that of the control group at 0.64, 1.28, and 6.4 mg/ml. The bacteria and their colonies were examined using a scanning electron microscope. Boundaries between the antimicrobial activity region and non-antimicrobial activity region were observed around the paper disk, which was immersed in the extract with 32 mg/ml concentration. Bacterial colonization was not observed in the area with antimicrobial activity. This finding suggests that ASF extracts can inhibit the growth of some microorganisms in the oral cavity, in addition to the effects of these extracts known to date. In particular, ASF extracts may be used as a preparation for preventing dental caries by adding the extract to the toothpaste or oral mouthwash.

• Journal of Navigation and Port Research
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• v.34 no.8
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• pp.603-607
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• 2010

The LORAN system had been used widely and it was an essential navigation aid for ships in the ocean until the GPS is adopted actively. In particular, it was essential functionality for the ships to sail the oceans. According to the advancement of industry, however, the current accuracy of traditional Loran is insufficient for the utilization of harbour approach, land navigation, and the field of survey and timing. Therefore it is necessary that the study on the improvement of the positioning accuracy of Loran. The one of the improving methods is to measure and compensate the propagation time delay between the transmitter and user's receiver, which is called as additional secondary factor (ASF). In this study, we measured the ASF between the Pohang master transmitting station (9930M) and four points where locate within 33 km apart from the transmitting station, using the measuring technique of the absolute time delay without a time of coincidence (TOC) table. As the result of measurement, the ranging error caused by the propagation delay was about 210 m at 33 km, however it can be reduced up to 40 m with ASF compensation.

• Journal of Korean Medicine for Obesity Research
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• v.16 no.2
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• pp.133-137
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• 2016

This study was conducted to investigate the effects of wild ginseng complex (WGC) pharmacopuncture combined with hyperthermia on abdominal obesity in post-menopause women. Two post-menopausal women were treated 5 times in 2 weeks with WGC pharmacopuncture on abdominal acupoints and 30 minutes of hyperthermia on abdominal area. Before treatment and after 5 treatments were finished, body weight (BW), body mass index (BMI), body fat ratio, waist circumference (WC), waist hip ratio, thickness of abdominal subcutaneous fat (ASF) were measured. In case 1, BW, BMI, WC, and ASF were reduced by 0.6 kg, $0.2kg/m^2$, 6 cm, and 18 mm respectively. In case 2, BW, BMI, WC, and ASF were reduced by 0.4 kg, $0.17kg/m^2$, 4.6 cm, and 12 mm respectively. This suggest that combined therapy of WGC pharmacopuncture and hyperthermia might be an effective treatment for abdominal obesity in post menopause women.