• Journal of the Korea Institute of Military Science and Technology
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• v.13 no.1
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• pp.41-49
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• 2010

In this paper, we propose a hierarchical RAM simulation model framework which are used to analyze the RAM specifications on the concept refinement phase. The hierarchical RAM simulation model framework consists of RAM simulation models, class library and each model's input and output data lists. The hierarchical RAM simulation models are co-operated with 3 kinds of model - type I, II, III. Type I, II models are used to analyze the target operational availability and Type III is used to establish the initial RAM specifications. Each model's input and output data lists are defined by considering each model's purpose of RAM analysis. The class library is arranged with each model's classes for implementing the hierarchical simulation models. The proposed framework may be applied for executing the RAM activities effectively.

• Journal of Yeungnam Medical Science
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• v.14 no.2
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• pp.399-414
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• 1997

There are several factors concerning to anemia in chronic renal failure patients. But when rHuEPO is used, most of these factors can be overcome, and the levels of hemoglobin are increased. However, about 10% of the renal failure patients represent rHuEPO-resistant anemia eventhough high dosage of rHuEPO. For these cases, desferrioxamine can be applied to correct rHuEPO resistnacy, and many mechanism of DFO are arguing. So we are going to know whether DFO can be applied to correct anemia of the such patients, how long its effect can be continued. The seven pateients as experimental group(DFO+EPO) who represent refractoriness to rHuEPO and the other seven patients as control group(EPO) were included. Experimental group had lower than 9 g/dL of hemoglobin levels despite high rHuEPO dosage (more than 4000U/Wk) and showed normocytic normochromic anemia. There were no definitve causes of anemia such as hemorrhage or iron deficiency. Control group patients had similar characteristics in age, mean dialysis duration but showed adequate response to rHuEPO. DFO was administered to experimental group for 8 weeks along with rHuEPO(the rHuEPO individual mean dosage had been determined by mean dosage of the previous 6 months. Total mean dosage; 123.5 U/Kg/Wk). After 8 weeks of DFO administration, the hemoglobin and rHuEPO dosage levels were checked for 15 consecutive months. It should be noted that the patients determined their own rHuEPO dosage levels according to hemoglobin levels and economic status. In conrol group, rHuEPO was administered by the same method used in experimental group without DFO through the same period. Fifteen months of observation period after DFO trial were divided as Time I(7 months after DFO trial) and Time II(8 months after Time I). The results are as follows: Before DFO trial, mean hemoglobin level of experimental group was 7.8 g/dL, which is similar level(p>0.05) to control group(mean Hb; 8.2 g/dL). But in experimental group, significantly(p<0.05) higher dosages of rHuEPO(mean; 123.5 U/Kg/Wk) than control group (mean; 41.6 U/Kg/Wk) had been used. It means resistancy to rHuEPO of experimental group. But after DFO trial, the hemoglobin levels of the experimental group were increased significantly(p<0.05), and these effect were continued to Time II.(Time I; mean 8.6g/dL, Time II; mean 8.6g/dL) The effects of DFO to hemoglobin were continued for 15 months after DFO trial with similar degree through Time I, Time II. Also, rHuEPO dosages used in the experimental group were decreased to similar levels of the control group after DFO trial and these effect were also continued for 15 months(Time I; mean 48.1 U/Kg/Wk. Time II; mean 51.8 U/Kg/Wk). In the same period, hemoglobin levels and rHuEPO dosages used in the control group were not changed significantly. Notibly, hemoglobin increment and rHuEPO usage decrement in experimental group were showed maxilly in the 1st month after DFO trial. That is, after the use of DFO, erythopoiesis was enhanced with a reduced rHuEPO dosage. So we think rHuEPO reisistancy can be overcome by DFO therapy. In conclusion, the DFO can improve the anemia caused by chronic renal failure at least over 1 year, and hence, can reduce the dosage of rHuEPO for anemia correction. Additional studies in order to determine the mechanism of DFO on erythropoiesis and careful attention to potential side effects of DFO will be needed.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.32 no.2
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• pp.107-111
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• 2010

Purpose: The aim of this study is to compare the stability between Mg-incorporated implant, TiUnite and Machined implant. Materials and Methods: Premolars of 3 Mini pigs (24 months) were extracted. After 2 months later, total 27 fixtures of implants (9 of each design : Machined/ TiUnite/ Mg-incorporated) were inserted into the mandible of 3 mini-pig. Implant stability was estimated by RFA in installation to 2, 4 & 6 weeks. Statistical analysis of RFA values was performed with time and between groups using repeated measure ANOVA and turkey's multiple comparison test. Results: In analyzing the mean value for the observation periods, three types of implants yielded a slight decrease in RFA mean value after 2 week, followed by increase at 4-6 weeks. Mg incorporated oxidized implants demonstrated significantly higher RFA mean values at 6 weeks comparing other groups. The difference of RFA value with time and between groups was statistically significant. Conclusion: We concluded that Mg implants may reduce failure rates of clinical implants In the early period of bone healing and Mg implants may shorten the bone healing time from surgery to functional loading.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2010.11a
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• pp.143-148
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• 2010

A Statistical methods are used to determine the reliability of a Fuel Boost Pump for aviation. Failures are referenced from failure reports. The failure-free periods between successive failure events are evaluated in the form of weibull distribution. The results of analysis were calculated shape factor, scale parameter and mean time to failure. It found that the reason of failure is wear-out period.

• Proceedings of the KSR Conference
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• 2004.10a
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• pp.539-544
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• 2004

In this paper, we present reliability modeling and analysis method of the Automated Guideway Transit(AGT) vehicle system using analytical models, based on Markov Chains. The Markov model can express state transition of the AGT vehicle sys. that is considered to be in one of four states, such as basic operating (0), minor delay(1), major delay(2) and non-operating(3) state. The proposed Markov model is illustrated with a numerical example and cases to find a steady state availability, MTBF(mean time between failures), and MTTR(mean time to repair) under specified failure and repair rate arc demonstrated.

• Journal of the military operations research society of Korea
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• v.27 no.1
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• pp.58-72
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• 2001

This research deals with the weapon system RAM which is the reliability, availability and maintainability for weapon systems. This weapon system RAM is one of very important factors because it is related to the life cycle cost and combat readiness of weapon systems. Therefore, in this research we introduce the weapon system RAM and analyze the problems of weapon system RAM management during system life cycle including acquisition period. Finally we suggest an alternative to improve the weapon system RAM in various agencies which are the department of defense and army headquarter level, etc., in the process of defense acquisition.

• Journal of the Korean Data and Information Science Society
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• v.20 no.6
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• pp.1169-1175
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• 2009

In this paper, the inferences of data obtained from periodic inspection and type I censoring for the step-stress accelerated life test are studied. The exponential distribution with a failure rate function that a log-linear function of stress and the tampered failure rate model are considered. The maximum likelihood estimators of the model parameters are estimated and also the optimal stress change time which minimize the asymptotic variance of maximum likelihood estimators of parameters is determined. A numerical example will be given to illustrate the proposed inferential procedures and the sensitivity of the asymptotic variance of the estimated mean by the guessed parameters is investigated.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2001.04a
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• pp.59-62
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• 2001

Reliability engineering is regarded as the major and important roll for all industry. And advanced manufacturing systems with high speed and intelligent have been developing for the betterment of machining ability. In this study, we have systemized evaluation of reliability for machinery system. We proposed the reliability assessment and design review method using analyzing critical units of high speed and intelligent machine system. In addition, we have not only designed and developed test bed system for acquiring reliability data, but also apply QFD technique for satisfying quality function which is provided in design phase. From this study, we will expect to guide and introduce the reliability engineering in developing and processing phase of high quality product.

• Journal of Korean Institute of Industrial Engineers
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• v.18 no.1
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• pp.37-45
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• 1992

Common assumption we frequently encounter in early models of software reliability is that no new faults are introduced during the fault removal process. In real life, however, there are situations in which new faults are introducted as a result of imperfect debugging. This study alleviating this assumption by introducting the probability of perfect error-correction is an extension of Littlewood's work. In this model, the system reliability, failure rates, mean time to failure and average failure frequency are obtained. Here, when the probability of perfect error-correction is one, the results appear identical with those of the previous studies. In the respect that the results of previous studies are special cases of this model, the model developed can be considered as a generalized one.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.9 no.2
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• pp.141-147
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• 2016

NHPP software reliability models for failure analysis can have, in the literature, exhibit either constant, monotonic increasing or monotonic decreasing failure occurrence rates per fault. In this paper, infinite failures NHPP models that repairing software failure point in time reflects the situation, was presented for comparing property. Commonly used in the field of software reliability based on Flexible Weibull extension distribution software reliability of infinite failures was presented for comparison problem. The result is that a relatively small shaping parameter was effectively. The parameters estimation using maximum likelihood estimation was conducted and model selection was performed using the mean square error and the coefficient of determination.. In this research, software developers to identify software failure property follows shape parameter, some extent be able to help is considered.