• Proceedings of the Korean Geotechical Society Conference
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• 2005.03a
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• pp.1126-1133
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• 2005

The effects of mean particle size and uniformity coefficient of dredged soils to the liquefaction resistance strength and dynamic characteristics are experimentally studied in this paper. Representative 4 mean particle sizes and 3 uniformity coefficients were selected and 12 representative particle size distribution curves which have different mean particle sizes and uniformity coefficients, were artificially manufactured using the real dredged river soil. Cyclic triaxial tests and torsional shear tests were carried out to analyze the effect of mean particle size and uniformity coefficient to the liquefaction resistance strength and dynamic characteristics of soils.

• Structural Engineering and Mechanics
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• v.36 no.1
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• pp.19-36
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• 2010

The load and resistance factors are generally obtained using the First Order Reliability Method (FORM), in which the design point should be determined and derivative-based iterations have to be used. In this paper, a simple method for estimating the load and resistance factors using the first four moments of the basic random variables is proposed and a simple formula for the target mean resistance is also proposed to avoid iteration computation. Unlike the currently used method, the load and resistance factors can be determined using the proposed method even when the probability density functions (PDFs) of the basic random variables are not available. Moreover, the proposed method does not need either the iterative computation of derivatives or any design points. Thus, the present method provides a more convenient and effective way to estimate the load and resistance factors in practical engineering. Numerical examples are presented to demonstrate the advantages of the proposed fourth moment method for determining the load and resistance factors.

• Journal of Korean Neurosurgical Society
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• v.48 no.4
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• pp.319-324
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• 2010

Objective : The aim of this study was to analyze the correlation between thromboembolic complications and anti platelet drugs before and after neurointervention. Methods : Blood samples and radiographic data of patients who received a neurointervention (coil embolization, stent placement or both) were collected prospectively. Rapid platelet function assay-aspirin (RPFA-ASA) was used to calculate aspirin resistance in aspirin reaction units (ARU). For clopidogrel resistance, a P2Y12 assay was used to analyze the percentage of platelet inhibition. ARU > 550 and platelet inhibition < 40% were defined as aspirin and clopidogrel resistance, respectively. Results : Both aspirin and clopidogrel oral pills were administered in fifty-three patients before and after neurointerventional procedures. The mean resistance values of all patients were 484 ARU and < 39%. Ten (17.0%) of 53 patients showed resistance to aspirin with an average of 597 ARU, and 33 (62.3%) of 53 patients showed resistance to clopidogrel with an average of < 26%. Ten patients demonstrated resistance to both drugs, 5 of which suffered a thromboembolic complication after neurointervention (mean values : 640 ARU and platelet inhibition < 23%). Diabetic patients and patients with hypercholesterolemia displayed mean aspirin resistances of 513.7 and 501.8 ARU, and mean clopidogrel resistances of < 33.8% and < 40.7%, respectively. Conclusion : Identifying individuals with poor platelet inhibition using standard regimens is of great clinical importance and may help prevent cerebral ischemic events in the future. Neurointerventional research should focus on ideal doses, timing, choices, safety, and reliable measurements of anti platelet drug therapy, as well as confirming the clinical relevance of aggregometry in cerebrovascular patients.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.1 no.1
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• pp.54-62
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• 1998

This study measured the shearing resistance of the roots of the Sasamorpha purpurascens, Miscanthus sinensis, Lespedeza cyrtobotrya by the tensile strength gained through their individual tensile test for the Root Reinforcement Model. The results to have measured this stress by experiment are as follows. 1) The mean root diameter of the Lespedeza cyrtobotrya used for this experiment was 2.19mm and the mean tensile stress was calculated as $929.489kgf/cm^2$. As for the Sasamorpha purpurascens, its mean root diameter was 1.727mm, and the mean tensile stress was $292.069kgf/cm^2$. And as for the Miscanthus sinensis, its mean root diameter was 0.814mm, and the mean tensile stress was $696.947kgf/cm^2$. And so, it was grasped that Lespedeza cyrtobotrya was highest in tensile stress. 2) ${\Delta}Cr(kg/cm^2)$ of the shearing resistance calculated by estimating the areal ratio of roots at $10^{-3}$ is $1.069kg/cm^2$ in Lespedeza cyrtobotrya, $0.336kg/cm^2$ in Sasamorpha purpurascens, and $0.801kg/cm^2$ in Miscanthus sinensis. That is, Lespedeza cyrtobotrya has the highest shearing resistance. However, since a precise analysis of the controlled factors of the slope analyses are demanded for more accurate dynamic analyses, the future demands a study on this.

• Journal of the Korean Geotechnical Society
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• v.21 no.7
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• pp.13-20
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• 2005

For experimental study on the effect of particle size distribution on the liquefaction resistance strength, particle size distribution curves of the dredged soil were investigated. In this process, four mean particle sizes and three uniformity coefficients were defined representatively and twelve representative particle size distribution curves which have different mean particle size and uniformity coefficient, were defined and manufactured by using the real dredged river soil. Cyclic triaxial tests and resonant column tests were carried out to analyze the effect of mean particle size and uniformity coefficient on the liquefaction resistance strength and dynamic characteristics.

• Journal of the Korean Society of Marine Environment & Safety
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• v.21 no.3
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• pp.240-245
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• 2015

In this study, experiments were performed using a model of a very large crude oil carrier (VLCC), which is a typical blunt ship, in a wave-making towing tank. The aim of the experiments was to determine the effect of added resistance in waves on the various operating conditions of a VLCC. An analysis of the results was conducted to determine the characteristics of resistance performance in waves. In addition, the characteristics of added resistance on a tanker were analyzed under irregular waves based upon the above result. The experimental results showed that added resistance was the highest around ${\lambda}/L=1.0$, and the added resistance increased with the increase of the ship speed. Furthermore, under even keel conditions, the added resistance was higher than that under the trim changes, and the smallest added resistance was measured at the trim by the stern. Based on the experimental results, this study proposes effective operating conditions by analyzing the characteristics of the mean added resistance and the expected extreme response in irregular waves.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.19 no.4
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• pp.251-258
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• 2016

Purpose: This study aimed to evaluate the utility of acanthosis nigricans (AN) severity as an index for predicting insulin resistance in obese children. Methods: The subjects comprised 74 obese pediatric patients who attended the Department of Pediatrics at Chosun University Hospital between January 2013 and March 2016. Waist circumference; body mass index; blood pressure; fasting glucose and fasting insulin levels; lipid profile; aspartate transaminase, alanine transaminase, glycated hemoglobin, C-peptide, and uric acid levels; and homeostatic model assessment insulin resistance (HOMA-IR) and quantitative insulin check sensitivity index (QUICKI) scores were compared between subjects with AN and those without AN. Receiver operating characteristic curves were used to investigate the utility of the AN score in predicting insulin resistance. HOMA-IR and QUICKI were compared according to AN severity. Results: The With AN group had higher fasting insulin levels ($24.1{\pm}21.0\;mU/L$ vs. $9.8{\pm}3.6\;mU/L$, p<0.001) and HOMA-IR score ($5.74{\pm}4.71$ vs. $2.14{\pm}0.86$, p<0.001) than the Without AN group. The AN score used to predict insulin resistance was 3 points or more (sensitivity 56.8%, specificity 83.9%). HOMA-IR scores increased with AN severity, from the Without AN group (mean, 2.15; 95% confidence interval [CI], 1.72-2.57) to the Mild AN (mean, 4.15; 95% CI, 3.04-5.25) and Severe AN groups (mean, 7.22; 95% CI, 5.08-9.35; p<0.001). Conclusion: Insulin resistance worsens with increasing AN severity, and patients with Severe AN (AN score ${\geq}3$) are at increased risk of insulin resistance.

• Journal of Ocean Engineering and Technology
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• v.11 no.2
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• pp.91-99
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• 1997

This paper presents theoretical formulations and numerical computations for predicting first-and second-order hydrodynamic force on a ship advvancing in waves. The theoretical formulation leads to linearized radiation and diffration problems solving the three-dimensional Green function integral equations over the mean wetted body surface. Green function representing a translating and pulsating source potantial for infinite water depth is used. In order to solve integral equations for three dimentional flows using Green function efficiently, the Hoff's method is adopted for numerical calculation of the Green function. Based on the first-order solution, the mean seconder-order forces and moments are obtained by directly integrating second-order pressure over the mean wetted body surface. The calculated items are carried out for analyzing the seakeeping characteristics of Series 60. The calculated items are hydrodynamic coefficients, wave exciting forces, frequency response functions and addd resistance in waves.

• Korean Journal of Exercise Nutrition
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• v.24 no.1
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• pp.29-36
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• 2020

[Purpose] The purpose of this study was to investigate the effects of short-term creatine intake on muscle fatigue induced by resistance exercise in healthy adolescent men, i.e., lactic acid concentration and wrist and head tremor measured by an accelerometer. [Methods] Twelve healthy adolescent men who had no experience with creatine intake were included. The subjects were randomly assigned to the creatine group and the placebo group, followed by 5 days of creatine and placebo intake, and 5 times of 5 sets of leg press, leg extension, bench press, and arm curl exercises at 70% repetition maximum (RM). The lactic acid concentration before and after exercising, rate of perceived exertion (RPE), and accelerometer-based wrist tremor and head tremor during exercise were measured. Subsequently, after 7 days to allow for creatine washout, the same exercise treatment and measurement were performed in each group after switching drug and placebo between the groups. [Results] The level of lactic acid before and after the acute resistance exercise trial was significantly lower in the creatine group than in the placebo group (P <0.05). The mean RPE during the resistance exercise was significantly lower in the creatine group than in the placebo group (P <0.05). There was no difference between the two groups in the mean wrist tremor during resistance exercise, but the mean head tremor values were significantly lower in the creatine group than in the placebo group in the arm curl, the last event of the exercise trials (P <0.05). [Conclusion] Short-term creatine intake reduces the blood fatigue factor increased by resistance exercise, and is thought to suppress fatigue, especially in the latter half of resistance exercise. Therefore, these findings indicate that short-term creatine intake can have an improved effect on anaerobic exercise performance.

• Transactions of the Korean Society of Automotive Engineers
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• v.21 no.4
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• pp.128-134
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• 2013

High bending collapse performance (maximum resistance force and mean resistance force) of body center pillar is an important design target for vehicle safety against side impact. In this study, effect of the upper section shape and the thickness of outer reinforcement on bending collapse performance was investigated for the center pillar of a large passenger car. First, through bending collapse analyses using simple models with uniform section, an optimized center pillar upper section was chosen. Next, bending collapse performance for various models of the actual center pillar with changing the thickness of outer reinforcement were analyzed. The finally designed model showed distinctive enhancement in bending collapse performance nearly without weight increase.