• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.3877-3880
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• 2016

Nausea and vomiting are among the most serious side effects of chemotherapy, in some cases leading to treatment interruption or chemotherapy dose reduction. Ginger has long been known as an antiemetic drug, used for conditions such as motion sickness, nausea-vomiting in pregnancy, and post-operation side effects. One hundred and fifty female patients with breast cancer entered this prospective study and were randomized to receive ginger (500 mg ginger powder, twice a day for 3 days) or placebo. One hundred and nineteen patients completed the study: 57 of them received ginger and 62 received ginger for the first 3 chemotherapy cycles. Mean age in all patients was 48.6 (25-79) years. After 1st chemotherapy, mean nausea in the ginger and control arms were 1.36 (${\pm}1.31$) and 1.46 (${\pm}1.28$) with no statistically significant difference. After the $2^{nd}$ chemotherapy session, nausea score was slightly more in the ginger group (1.36 versus 1.32). After $3^{rd}$ chemotherapy, mean nausea severity in control group was less than ginger group [1.37 (${\pm}1.14$), versus 1.42 (${\pm}1.30$)]. Considering all patients, nausea was slightly more severe in ginger arm. In ginger arm mean nausea score was 1.42 (${\pm}0.96$) and in control arm it was 1.40 (${\pm}0.92$). Mean vomiting scores after chemotherapy in ginger arm were 0.719 (${\pm}1.03$), 0.68 (${\pm}1.00$) and 0.77 (${\pm}1.18$). In control arm, mean vomiting was 0.983 (${\pm}1.23$), 1.03 (${\pm}1.22$) and 1.15 (${\pm}1.27$). In all sessions, ginger decreased vomiting severity from 1.4 (${\pm}1.04$) to 0.71 (${\pm}0.86$). None of the differences were significant. In those patients who received the AC regimen, vomiting was less severe ($0.64{\pm}0.87$) comparing to those who received placebo ($1.13{\pm}1.12$), which was statistically significant (p-Value <0.05). Further and larger studies are needed to draw conclusions.

• Transactions of the Korean Society of Automotive Engineers
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• v.21 no.4
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• pp.128-134
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• 2013

High bending collapse performance (maximum resistance force and mean resistance force) of body center pillar is an important design target for vehicle safety against side impact. In this study, effect of the upper section shape and the thickness of outer reinforcement on bending collapse performance was investigated for the center pillar of a large passenger car. First, through bending collapse analyses using simple models with uniform section, an optimized center pillar upper section was chosen. Next, bending collapse performance for various models of the actual center pillar with changing the thickness of outer reinforcement were analyzed. The finally designed model showed distinctive enhancement in bending collapse performance nearly without weight increase.

• Korean Journal of Applied Biomechanics
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• v.22 no.2
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• pp.183-191
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• 2012

The objective of this study was to evaluate the plantar foot pressure of skilled and unskilled players during a free throw. The experiment performed here in measured the movement route of the mean foot pressure, maximum foot pressure, and center of pressure in four event zones (ready, maximum knee flexion, release event, and maximum knee extension) for both groups while they were wearing the plantar foot pressure measurement equipment under identical conditions. The major findings are as follows. When getting ready (RD) during a free throw, the skilled player group had higher mean and maximum foot pressures, although neither variable showed significant differences statistically. For the maximum knee flexion (MF) during a free throw, the skilled player group had higher mean and maximum foot pressures, but only the mean foot pressure significantly differed statistically. For the release event (RE) during a free throw, the unskilled player group had higher mean and maximum foot pressures, but only the mean foot pressure significantly differed statistically. During the maximum knee extension (ME) of a free throw, the unskilled player group had a higher mean foot pressure, and the skilled player group had a higher maximum foot pressure. No significant correlation was found between the two groups. For the skilled player group, movement towards the center of pressure showed a stable form that moved from the rear to the front and from side to side during a free throw. For the unskilled player group, movement towards the center of pressure was unstable, which made it impossible to move from the rear to the front and from left to right.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.36S no.8
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• pp.30-38
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• 1999

On providing MPEG-2 video service through the ATM network, it is necessary for network provider to have the ATM QoS objectives in order to guarantee quality of service required by end users at the application layer. In this paper, the degradation of QoS caused by cell losses at application layer is assessed quantitatively by GIQ model considering AAL layer and is evaluated qualitatively by MOS from the viewpoint of the end users in order to analyze the relation between CLR and QoS of MPEG-2 video. From the simulation and empirical results, we know that CLR and $GIQ_{mean}$ for guaranteeing QoS of MOS grade 5(Excellent) are $CLR{\le}4{\times}10^7$ & $GIQ_{mean}{\ge}99.4%$ and those for guaranteeing QoS of MOS grade 4(Good) are $CLR{\le}2{\times}10^6$ & $GIQ_{mean}{\ge}99.705%$.

• Journal of Trauma and Injury
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• v.34 no.1
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• pp.13-20
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• 2021

Purpose: Nutritional therapy in the intensive care unit is an essential factor for patient progress. The purpose of this study was to compare resting energy expenditure (REE) calculated by prediction equations (PEs) to the REE measured by indirect calorimetry (IC) in trauma patients. Methods: Patients admitted to the trauma intensive care unit who received mechanical ventilation between January and December 2015 were enrolled. REE was measured by IC (CCM Express, MGC Diagnostics) and calculated by the following PEs: Harris-Benedict, Fleisch, Robertson and Reid, Ireton-Jones, and the maximum value (25 kcal/kg/day) of the European Society for Clinical Nutrition and Metabolism (ESPEN). All patients were ventilated at a fraction of inspired oxygen (FiO2) below 60%. Results: Of the 31 patients included in this study, 24 (77.4%) were men and seven (22.6%) were women. The mean age of the patients was 49.7±13.2 years, their mean weight was 68.1±9.6 kg, and their mean Injury Severity Score was 26.1±11.3. The mean respiratory quotient on IC was 0.93±0.19, and their mean FiO2 was 38.72%±6.97%. The mean REE measured by IC was 2,146±444.36 kcal/day, and the mean REE values calculated by the PEs were 1,509.39±205.34 kcal/day by the Harris and Benedict equation, 1,509.39±154.33 kcal/day by the Fleisch equation, and 1,443.39±159.61 kcal/day by the Robertson and Reid equation. The Ireton-Jones equation yielded a higher value (2,278.90±202.35 kcal/day), which was not significantly different from the value measured using IC (p=0.53). The ESPEN maximum value (1,704.03±449.36 kcal/day) was lower, but this difference was likewise not significant (p=0.127). Conclusions: The REE measured by IC was somewhat higher than that calculated using PEs. Further studies are needed to determine the proper nutritional support for trauma patients.

• Korean Journal of Transplantation
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• v.31 no.4
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• pp.200-206
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• 2017

Background: Risk factors for bone avascular necrosis (AVN), a common late complication after kidney transplantation (KT), are not well known. Methods: Patients that underwent living-donor KT at Asan Medical Center between January 2009 and July 2016 were included in this retrospective study to determine the incidence and risk factors for AVN after KT. Results: Among 1,570 patients that underwent living-donor KT, 33 (2.1%) developed AVN during a mean follow-up of 49.8±25.0 months. Additionally, AVN was diagnosed at a mean of 13.9±6.6 months after KT. The mean cumulative corticosteroid dose during the last follow-up in patients without AVN (9,108±3,400 mg) was higher than that that in patients with AVN (4,483±1,114 mg) until AVN development (P<0.01). More patients among those with AVN (n=4, 12.1%) underwent steroid pulse treatment because of biopsy-proven rejections during the first 6 months after KT than patients without AVN (n=68, 4.4%; P=0.04). Female (hazard ratio [HR], 2.29; P=0.04) and steroid pulse treatment during the first 6 months (HR, 2.31; P=0.02) were significant AVN risk factors as revealed by the Cox proportional multivariate analysis. However, no significant differences in rejection-free graft survival rates were observed between the two groups (P=0.67). Conclusions: Steroid pulse treatment within 6 months of KT and being female were independent risk factors for AVN development.

• The Journal of Korean Medicine
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• v.30 no.1
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• pp.95-108
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• 2009

Objectives: Uwhangchungsim-won (DC) has been used in various medical fields such as stroke, hypertension, atherosclerosis, autonomic imbalance and mental instability, etc. The aim of this study was to evaluate the effect of UC on cerebral hemodynamics and estimate the appropriate dose of UC. Methods: We studied changes of hyperventilation-induced cerebrovascular reactivity and mean blood flow velocity of middle cerebral arteries (MCA) using transcranial Doppler. We observed the changes of mean blood pressure, pulse rate and expiratory CO2 using S/5 Compact Anesthesia Monitor from 10 healthy young volunteers who were administered UC twice a day in the 1 st section and then once a day in the 2nd section. Results: Mean blood pressure tended to decrease at 1 hour and pulse rate tended to decrease at 2 hours after second administration. After 2 hours, mean blood pressure rose to state before administration, but pulse rate maintained from 2 hours to 4 hours. The changes were not statistically significant. Cerebral blood flow velocity in middle cerebral artery was not statistically significant after second administration. Cerebrovascular reactivity increased from 2 hours to 4 hours after second administration. Conclusions: This study provides that administration of UC twice a day is more effective on hyperventilation-induced cerebrovascular reactivity than administration of UC once a day.

• Journal of Environmental Health Sciences
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• v.15 no.2
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• pp.1-9
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• 1989

A pilot study was conducted in order to measure indoor and outdoor formaldehyde levels during August 3 - 22, 1988 in several underground spaces in Seoul. Formaldehyde concentrations were monitored during 1 week in selected sampling areas (subway station, underground shopping center, underpass, tunnel, underground parking lot) using passive formaldehyde monitors. In order to investigate a relationship between respiratory prevalence and levels of formaldehyde, each subject was asked to answer respiratory questions. The mean formaldehyde concentrations were 60.1 ppb in subway station, 122.2 ppb in underground shopping stores, 72.1 ppb in underpasses, 39.7 ppb in tunnel, and 75.9 ppb in underground parking lots, respectively. The mean indoor formaldehyde concentrations in underground environments varied from 28.6 ppb to 118.7 ppb. Generally, the mean formaldehyde concentrations in ticketing office in subway stations appeared higher than those level measured in platform. The mean formaldehyde concentrations of underground shopping center in Gangnam Terminal were higher than any other areas and it exceeded 100 ppb of the American Ambient Air Quality Standards of formaldehyde. Prevalence rates of respiratory symptoms of dwellers seemed to be related to higher indoor formaldehyde levels.

• Communications for Statistical Applications and Methods
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• v.13 no.3
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• pp.607-619
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• 2006

We consider the problem of testing the existence of change in mean and estimating the change-point when the data are from the normal distribution. A change-point estimator using the likelihood ratio test statistic, Gombay and Horvath (1990) test statistic, and nonparametric change-point estimator using Carlstein (1988) empirical distribution are studied when there exists one change-point in the mean. A power study is done to compare the change test statistics. And a comparison study of change-point estimators for estimation capability is done via simulations with S-plus software.

• The Journal of Korean Society for Radiation Therapy
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• v.9 no.1
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• pp.50-55
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• 1997

The optimal management of uveal melanoma is still a matter of controversy. To determine the effect of Gamma Knife surgery for patients with uveal malanoma. the authors reviewed the results of 5 patients underwent Gamma Knife sugery between Sep. 1993 and Dec. 1996. The mean age was 60.7 years ranging from 42.5 to 76.5 years. Median follow-up was 13.29 months and the patient with follow up period more than 6 months was 4. The mean tumor volume was $3442 mm^3$(mean diameter 15.3 mm) and all patients were irradiated with a mean maximum dose of 74Gy(range $60\~80\;Gy$), using the $50\%$ isodose. After Gamma Knife surgery. one pateint showed complete disapperance in tumor size with follow-up 32 months, one enucleation due to progression, and 2 no interval change. In regard to vision, one patient blind. one enucleation, and 2 patients had no interval change. According to our experiences, Gamma Knife surgery for uveal melanoma be able to achieve local tumor control, spare the eyeball, and have possibility of save vision.