• Clinical and Experimental Pediatrics
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• v.49 no.11
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• pp.1125-1139
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• 2006

In 1991, the Ministry of Health & Social affairs adopted a nationwide service program for neonatal screening of phenylketonuria, galactosemia, maple syrup urine disease, homocystinuria, histidinemia & congenital hypothyroidism for newborns delivered from low class pregnant women registered in health centers. Government decreased the test items from six to two, PKU & congenital hypothyroidism to increase test numbers with same budget from 1995. Government decided to test PKU & hypothyroidism for all newborns from 1997. 78 laboratories wanted to participate for neonatal screening test in 1999. Government didn't decide laboratory center for a certain district and placed responsibility on free competition. Government are planning to test 573,000 newborns from 1998, Government decided to screen 6 items PKU, congenital hypothyroidism, maple syrup urine disese, homocystinuria, galactosemia and congenital adrenal hyperplasia from 2006. 17 laboratores are participating now. The cost of screening test is supported by both the federal government and local government on a 40-60 basis. In case a patient with an inherited metabolic disease is diagnosed by screening of government program, special milk is provided at government's expense. Interlaboratory quality control was started 6 times a year from 1994. According to the government project, 3,707,773 newborns were screened. 86 PKU, 718 congenital hypothyroidism were detected. So incidence of PKU is 1/43,114 and congenital hypothyroidism is 1/4,612. Maeil dairy company produced new special formula for PKU, MMA and PA, MSUD, urea cycle disorder, homocystinuria, isovaleric acidemia from Oct. 1999. The cost benefit of performing screening procedures coupled with treatment has been estimated to be as high as 1.77 times in PKU, 11.11 times in congenital hypothyroidism than cost without screening. We are trying to increase the budget to test all newborns for Tandem mass sereening & Wilson disease from 2008. Now it is a very important problem to decrease laboratory numbers of neonatal screening in Korea. So we are considering 4-5 central laboratories which cover all newborns and are equipped with tandem mass spectrometer & enzyme immunoassay for TSH, 17OHP & enzyme colorimetric assay for galactose.

• Transactions of the Korean Society of Automotive Engineers
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• v.5 no.5
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• pp.51-66
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• 1997

A heat transfer model of the intake valve in a spark ignition engine is presented, which is calibrated with a number of the valve temperature profiles measured during engine warm-up for the gaseous fuel(propane). The valve is divided into four identical elements for which the assumption of lumped thermal mass is applied. The calibration is made so that the difference between the measued and simulated valve temperatures becomes minimal. Then the model is applied to the cases of the liquid fuel(indolene) to estimate the amount of the liquid fuel vaporized from the intake valve by assuming that fuel evaporation accounts for the deficit of the heat balance budget. The results of the model show quantitative contribution of each heat transfer source to the heat balance. The behavior of the calculated mass fraction of the fuel vaporized from the intake valve explains how the liquid fuel evaporate during engine warm-up. The mass fraction at warmed-up condition is closely related with the fraction directly targeted on the valve back by the fuel spray geometry.

• Journal of the korean society of oceanography
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• v.38 no.1
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• pp.11-16
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• 2003

The three dimensional structure of thermohaline circulation in a D-plane is investigated using a conceptual two layer model and a scaling argument. In this simple model, the water mass formation region is excluded. The upper layer represents the oceans above the main thermocline. The lower layer represents the deep ocean below the thermocline and is much thicker than the upper layer. In each layer, geostrophy and the linear vorticity balance are assumed. The cross interfacial velocity that compensates for the deep water mass formation balances downward heat diffusion from the top. From the above relations, we can determine the thickness of the upper layer, which is the same as thermocline depth. The results we get is basically the same as that we get for an f-plane ocean or the classical thermocline theory. Mass budget using the velocity scales from the scaling argument shows that western boundary and interior transports are much larger than the net meridional transport. Therefore in the thermohaline circulation, horizontal circulation is much stronger than the vertical circulation occuring on a meridional plane.

• Journal of the Korean Society for Marine Environment & Energy
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• v.12 no.4
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• pp.248-254
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• 2009

Budgets of fresh water, salt, DIP and DIN in the Youngsan river estuary were estimated seasonally in order to clarify the characteristics of material cycling and flux of nutrients with a simple box model. Inflow volumes of freshwater into system was approximately $36.481{\times}10^6{\sim}663.634{\times}10^6m^3/month$ and existing water mass of freshwater in system calculated by salt budget was approximately $2.515{\times}10^6{\sim}5.812{\times}10^6m^3$. Mean residence time of freshwater was calculated to be about 0.26~2.03 day. water exchange $1,248{\times}10^6{\sim}9,489{\times}10^6m^3/month$ assumed with salinity between estuary and adjacent ocean. Inflow mass of DIN and DIN were approximately 76.63~1,149.91 ton/month and 2.91~61.22 ton/month, respectively. Residence times of DIP and DIN were calculated to be 0.45~1.10 day and 0.28~1.92 day, respectively. The ratio of water residence time versus DIP, DIN residence time was calculated that freshwater residence time was longer than DIP, DIN residence time except for summer season. Thus, We assume that circulation of Nutrients in the system will happen rapidly except for summer season. Specially DIP in Winter could assume to outer input source existence because of seawater inflow in system and high DIP concentration in open sea.

• Korean Journal of Soil Science and Fertilizer
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• v.49 no.1
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• pp.60-65
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• 2016

The main objective of this research was to estimate the total mass of nitrogen discharged from various sources in paddy field area of South Korea in 2010 and 2013. Input and output budgets for nitrogen were estimated by mass balance approach. The mass balance approach reduces the effect of flow variations, and the large scale approach minimizes local effects, resulting in easier and faster establishment of strategy for nonpoint pollution problems. Nitrogen inputs were chemical fertilizer, compost, atmospheric deposition, biological fixation, and agricultural water, while crop uptake, denitrification, volatilization, and infiltration were nitrogen outputs. The estimated total nitrogen inputs for paddy field in South Korea were $266,211ton\;yr^{-1}$, $260,729ton\;yr^{-1}$, while those of total nitrogen outputs were $168,463ton\;yr^{-1}$, $164,994ton\;yr^{-1}$ in 2010 and 2013, respectively. Annual amounts of potential nitrogen outflow from paddy field were $97,748ton\;yr^{-1}$, $95,735ton\;yr^{-1}$ in 2010 and 2013. Also, annual rate of potential nitrogen outflow were 36.7%, 36.7% in 2010 and 2013, respectively.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.1
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• pp.49.1-49.1
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• 2017

In order to investigate the origin of multiple stellar populations in the halo and bulge of the Milky Way, we have constructed chemical evolution models for the low-mass proto-Galactic subsystems such as globular clusters (GCs). Unlike previous studies, we assume that supernova blast waves undergo blowout without expelling the pre-enriched gas, while relatively slow winds of massive stars, together with the winds and ejecta from low and intermediate mass asymptotic giant branch stars, are all locally retained in these less massive systems. We first applied these models to investigate the origin of super-helium-rich red clump stars in the metal-rich bulge as recently suggested by Lee et al. (2015). We find that chemical enrichments by the winds of massive stars can naturally reproduce the required helium enhancement (dY/dZ = 6) for the second generation stars. Disruption of these "building blocks" in a hierarchical merging paradigm would have provided helium enhanced stars to the bulge field. Interestingly, we also find that the observed Na-O anticorrelation in metal-poor GCs can be reproduced, when multiple episodes of starbursts are allowed to continue in these subsystems. Specific star formation history with decreasing time intervals between the stellar generations, however, is required to obtain this result, as would be expected from the orbital evolution of these subsystems in a proto-Galaxy. The "mass budget problem" is also much alleviated by our models without ad-hoc assumptions on star formation efficiency and initial mass function.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.1
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• pp.46.1-46.1
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• 2018

In order to investigate the origin of multiple stellar populations in the halo and bulge of the Milky Way, we have constructed chemical evolution models for the low-mass proto-Galactic subsystems such as globular clusters. Unlike previous studies, we assume that supernova blast waves undergo blowout without expelling the pre-enriched gas, while relatively slow winds of massive stars, together with the winds and ejecta from low and intermediate mass asymptotic-giant-branch stars, are all locally retained in these less massive systems. We find that the observed Na-O anti-correlations in metal-poor GCs can be reproduced when multiple episodes of starbursts are allowed to continue in these subsystems. A specific form of star formation history with decreasing time intervals between the stellar generations, however, is required to obtain this result, which is in good agreement with the parameters obtained from our stellar evolution models for the horizontal-branch. The "mass budget problem" is also much alleviated by our models without ad-hoc assumptions on star formation efficiency and initial mass function. We also applied these models to investigate the origin of super helium-rich red clump stars in the metal-rich bulge as recently suggested by Lee et al. (2015). We find that chemical enrichments by the winds of massive stars can naturally reproduce the required helium enhancement (dY/dZ = 6) for the second-generation stars. Disruption of proto-globular clusters in a hierarchical merging paradigm would have provided helium enhanced stars to the bulge field.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.283-287
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• 2015

Within the context of the hugely successful SAGE-LMC and SAGE-SMC surveys, Spitzer photometry observations of the Large and Small Magellanic Clouds have revealed millions of infrared point sources in each galaxy. The brightest infrared sources are generally dust producing and mass-losing evolved stars, and several tens of thousands of such stars have been classified. After photometrically classifying these objects, the dust production by several kinds of evolved stars - such as Asymptotic Giant Branch stars and Red Supergiants - can be determined. SAGE-Spec is the spectroscopic follow-up to the SAGE-LMC survey, and it has obtained Spitzer-IRS $5-40{\mu}m$ spectroscopy of about 200 sources in the LMC. Combined with archival data from other programs, observations at a total of ~1000 pointings have been obtained in the LMC, while ~250 IRS pointings were observed in the SMC. Of these, a few hundred pointings represent dust producing and mass-losing evolved stars, covering a range in colors, luminosities, and thus mass-loss rates. Red Supergiants and O-rich and C-rich AGB stars - the main dust producers - are well represented in the spectroscopic sample. This paper will summarize what we know about the mineralogy of dust producing evolved stars, and discuss their relative importance in the total dust budget.

• Journal of the korean society of oceanography
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• v.37 no.3
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• pp.117-124
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• 2002

Anthropogenic changes have been made to the water budget for the Mediterranean Sea as a result of river diversion projects. The decrease in freshwater inflow to the Mediterranean represents an effective increase in the overall net evaporation over the basin. Hydraulic control models for the exchange between the Mediterranean and Atlantic through the Strait of Gibraltar predict that the salinity of the Mediterranean should increase if the net evaporation over the Mediterranean increases. Increases in the salinity of the deep waters in both the western and eastern Mediterranean basins have been observed. The causes of such higher deep water salinity are attributed to increases in intermediate water salinity which are ultimately mixed down into the deep sea during wintertime buoyancy loss events. The pattern of the Mediterranean salinity increase is instructive for understanding how the water mass properties in a basin change over time as a result of anthropogenic changes.

• Journal of Korean Society for Atmospheric Environment
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• v.26 no.2
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• pp.118-136
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• 2010

Photochemical characteristics of ozone ($O_3$) and its precursors such as $O_3$ budget and $O_3-NO_x$-VOC sensitivity were analyzed in different physico-chemical properties of air masses around the Mexico City Metropolitan Area (MCMA) using aircraft observations during March 2006. The physico-chemical properties of air masses were categorized into 5 groups: boundary layer (BL), biomass burning (BB), free tropospheric continent (FTCO) and marine (FTMA), and Tula industrial complex (TIC). Results from the $O_3$ budget analysis indicated that $O_3$ production for BL, FTCO, and FTMA (for BB and TIC) was mainly controlled by a photochemical production pathway, a reaction of NO with $HO_2$ (with $RO_2$), while the main pathway of photochemical $O_3$ destruction for BL, FTCO, and FTMA (for BB and TIC) was a reaction of $HO_2$ with $O_3$ (of $H_2$ with $O^1$(D)). In addition, most of air mass categories (especially FTCO) were estimated to be $NO_x$-sensitive for $O_3$ production with lower $NO_y$, higher ratios of the other indicator species (e.g., $O_3/(NO_y-NO_x$), $H_2O_2/HNO_3$, etc.), and the lower removal rate of radicals ($\leq$0.5) by the reaction of OH with $NO_2$ than those of the VOC-sensitive condition.