• 제목/요약/키워드: Mass-production

검색결과 3,581건 처리시간 0.039초

Rapid and Quantitative Analysis of Clavulanic Acid Production by the Combination of Pyrolysis Mass Spectrometry and Artificial Neural Network

  • Kang, Sung-Gyun;Lee, Dae-Hoon;Ward, Alan-C.;Lee, Kye-Joon
    • Journal of Microbiology and Biotechnology
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    • 제8권5호
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    • pp.523-530
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    • 1998
  • Rapid and quantitative analysis of physiological change and clavulanic acid production was studied by the combination of pyrolysis mass spectrometry (PyMS) and artificial neural network (ANN) in Streptomyces clavuligerus. Firstly, the continuous culture studies were carried out to get the physiological background and PyMS samples. Clavulanic acid production was inversely related to growth rate: Mycelium growth and $q_{cal}$ were optimum at 0.1 $h^{-1}\; and \;0.025 h^{-1}$ respectively. Changes in specific nutrient uptake rates ($q_{gly}$ and $q_{amn}$) also affected clavulanic acid production since clavulanic acid production appeared to be stimulated by the limitation of carbon and nitrogen. Fermentation broth containing mycelium taken from continuous cultures was analyzed by PyMS, and the PyMS spectra were analyzed with multivariate statistics. PCCV plots revealed that samples harvested under the same culture condition were clustered together but samples from different culture conditions formed separate clusters. To deconvolute the pyrolysis mass spectra so as to obtain quantitative information on the concentration of clavulanic acid, ANN was trained on Py MS data using a radial basis function classifier. The results showed that the physiological stages with different growth rate were successfully differentiated and it was possible to monitor the clavulanic acid production precisely and rapidly.

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High Cell Density Cultivation of Pseudomonas oleovorans for the Production of Poly(3-Hydroxyalkanoates)

  • Lee, Sang-Yup
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제1권1호
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    • pp.51-53
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    • 1996
  • Fed-batch culture of Pseudomonas oleovorans was carried out for the production of medium-chain-length polyhydroxyalkanoates (MCL-PHAs) using octanoate as a carbon source. Octanoate and the salt solution containing ammounium sulfate and magnesium sulfate were intermittently fed in the course of fermentation. Cell mass and PHA concentrations of 42.8 and 16.8g/L, respectively, could be obtained in 40 h. The PHA content and the PHA productivity were 39.2% and 0.42 g PHA/L-h, respectively. The yields of cell mass and PHA were 0.71 g dry cell mass/g octanoate and 0.28g PHA/g octanoate, respectively. Therefore, octanoate can be used for the production of MCL-PHAs to a high concentration with high productivity.

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A Method of Squeegee pressure Optimization for Mass Production Thick Film Heaters Using SPC and Neural Network

  • Luckchonlatee, Chayut;Chaisawat, Ake
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2002년도 ITC-CSCC -1
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    • pp.22-25
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    • 2002
  • The Mass production of ceramic heater has encountered with the estimation for the proper parameters of the printing conditions. This paper presents a method to estimate the squeegee pressure. It uses resistance distribution from the trial run with approximate squeegee pressure which comes from statistical process control (SPC). Then, the resistance distribution and its total resistance are input to the backpropagation neural networks that can recognize resistance's distribution patterns. The value of output network derived from the input value can identify to the appropriate squeegee pressure. The experimental results are demonstrated In ensure the efficiency and the reliability of this method with the accuracy 96.75 percent. Indeed, embedded on this method will aid us to reduce the loss from the normal mass production.

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Accumulated organic matter, litterfall production, and decomposition tell us the status of litter dynamics in forests

  • Kim, Jae-Geun
    • Journal of Ecology and Environment
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    • 제35권2호
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    • pp.99-109
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    • 2012
  • Litterfall dynamics in forests are assessed by estimating biomass production and decomposition. However, there have been few studies on how litter dynamics impact the health and management of ecosystems. Here, a new approach to measure and assess ecosystem function is presented based on conventional methods using littertraps, litterbags, and the mass on the forest floor. To assess the status of litter dynamics, the decay rate (k) was estimated from a litterbag experiment, and removal rates ($k_i$) were determined from mass balance on the forest floor at 21 sites on three mountains in South Korea. The $k_3$ (organic mass ratio of $O_i$ and $O_e+O_a$ + A horizons in November) values in an equilibrium state in South Korea were within the range of $k{\pm}0.174$ when considering the annual variation of litterfall production. This study also suggests that sampling sites for these types of studies should be in the middle, not at the ends, of steady slopes on the forest floor.

미세조류 대량 생산용 광생물반응기 설계 (Design of Photobioreactor for Mass Production of Microalgae)

  • 안동규;조창규;정상화;이동기
    • 한국정밀공학회지
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    • 제28권2호
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    • pp.140-153
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    • 2011
  • The objective of this paper is to investigate into the design of photbioreactor for mass production of microalgae. Characteristics of previously developed photobioreactors were examined to obtain design factors, including light transfer, fluid dynamics and metabolic reactions, of the photobioreactor. Design technology of components related to the design factors, such as light sources, photobioreactor cases, spargers, mixer, etc., was discussed to improve the viability and the growth rate of microalgal and productivity of the photobioreactor. Finally a principle direction of the design for an airlift flat plane photobiorectors was investigated.

WS$_2$ 고체윤활제의 양산 및 적용 (Mass-production of WS$_2$ Solid Lubricant and Its applications)

  • 신동우;최인혁;윤대현;김경도
    • 한국윤활학회:학술대회논문집
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    • 한국윤활학회 1998년도 제28회 추계학술대회
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    • pp.221-226
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    • 1998
  • The processing conditions for the mass production of platelet WS$_2$ lubricant powder were optimized. The mixture of tungsten and sulfur powders was sealed in a vacuum of 10$^{-3}$ torr and heat-treated at 850$\circ$C for 2 h. The internal pressure of reaction chamber was maintained at certain level by controlling the release valve automatically. The reaction product was the platelet WS$_2$ powder with an average size of 15 $\mu$m. The synthesized WS$_2$ powder was then coated on the wiper-blade of automobiles and the commercial deep-grooved ball bearing using wet and dry coating methods, respectively. High lubricity and wear resistance of wet coated wiper-blade were confirmed by the life test of 70,000 cycles. The life-time of the ball bearing assembled after WS$_2$ coating onto each part increased 50 times compared to the non-coated ball bearing.

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전기화학적 에칭을 이용한 텅스텐 미세 탐침 가공 (Fabrication of Tungsten Probe using Electro-Chemical Etching)

  • 인치현;김규만;주종남
    • 한국정밀공학회지
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    • 제18권2호
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    • pp.111-118
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    • 2001
  • Tungsten probe is the most important part of a probe card, which is widely used for the performance test of wafer chips. Electro chemical etching becomes an exclusive choice for mass production of the tungsten probes. In the mass production, not only the shape of the probe but also the shape distribution of machined probes is important. A new method is proposed for the mass production of the tungsten probes. Tungsten wires are separated by a distance, and dipped into electrolyte. The dipping rate is controlled to shape the probes. Several experimental tests are performed to study the machining characteristics. From the test results, machining parameters including electrical conditions and anode position showed significant influences on the shape, repeatability, precision and quality of sharp tips.

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韓菓의 大量生産을 위한 연구 - 제조공정 및 기기설비류를 중심으로 - (A study on Mass Production of Korean Traditional Cookies - Manufacturing process and Machinery -)

  • 계승희;윤석인;염초애
    • 한국식품조리과학회지
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    • 제6권1호
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    • pp.67-73
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    • 1990
  • The purpose of this study is to investigate the manufacturing process for mass production of korean traditional cookies to be supplied to consumers with cheap price. Selected items for mass production is Yoomilkwa such as Yackwa. Maejackwa which preferred by consumers, and Chasookwa which was presented at royal party in YiDynasity. Standard mixing ratio of food material, manufacturing process, and machinery needed in each manufacturing process were suggested by the items of korean traditional cookies. Manufactured goods which is produced in large quantities by machinery are Yackwa model I, II Maejackwa model I, II, III, and Chasookwa model I, II.

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The Optimization of Hydrogen Reduction Process for Mass Production of Fe-8wt%Ni Nanoalloy Powder

  • Jung, Sung-Soo;Kang, Yun-Sung;Lee, Jai-Sung
    • 한국분말야금학회:학술대회논문집
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    • 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part2
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    • pp.1331-1332
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    • 2006
  • The present investigation has attemped to optimize hydrogen reduction process for the mass production of Fe-8wt%Ni nanoalloy powder from ball milled $Fe_2O_3-NiO$ powder. In-situ hygrometry study was performed to monitor the reduction behavior in real time through measurement of water vapor outflowing rate. It was found that the reduction process can be optimized by taking into account the apparent influence of water vapor trap in the reactor on reduction kinetics which strongly depends on gas flow rate, reactor volume and reduction.

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Facile mass production of thermally reduced graphene oxide

  • Lee, Seung-Jun;Park, Sung-Jin
    • Carbon letters
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    • 제13권1호
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    • pp.48-50
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    • 2012
  • Mass production of graphene-based materials, which have high specific surface area, is of importance for industrial applications. Herein, we report on a facile approach to produce thermally modified graphene oxide (TMG) in large quantities. We performed this experiment with a hot plate under environments that have relatively low temperature and no using inert gas. TMG materials showed a high specific surface area (430 $m^2g^{-1}$). Successful reduction was confirmed by elemental analysis, X-ray photoelectron spectroscopy, thermogravimetic analysis, and X-ray diffraction. The resulting materials might be useful for various applications such as in rechargeable batteries, as hydrogen storage materials, as nano-fillers in composites, in ultracapacitors, and in chemical/bio sensors.