• KSBB Journal
• /
• v.11 no.6
• /
• pp.704-711
• /
• 1996

An optimal process design of a foreign protein production system was carried out using a bioprocess flowsheeting software, BioPro Designer, with a capability of economic analysis. The flowsheeting program was applied to a production system of the tailspike protein of Salmonella phage P22, and helped save time and efforts in selecting an optimal process. A wild type tailspike and two types of mutant tailspikes, tsf G244\longrightarrow,R and Su A334\longrightarrowV, were considered in this study to show that the folding characteristics of foreign protein produced inside host influenced the selection of the best production system. An optimal production system for mature tailspike was chosen under the criterion of capital investment per unit mass of mature protein recovered.

• Journal of the Korea Safety Management & Science
• /
• v.15 no.4
• /
• pp.179-184
• /
• 2013

An accident from machine work is often fatal to the worker. This accident is mostly preventable through perfect process jig. In case of this machine work, however, the disaster frequently occurred because of the design which is not considered the beginning of product design, post-process and mass process of production. As for sand casting method, this has the merits of the production; the product is easily produced by manual labor. On the other hand, this method has the demerits of a bigger dimensional error contrary to other mass process of production. When the sand casting product is in machine work, there are various problems such as unsafe fix and excessive cutting, product desorption and rapid life depreciation of equipment and tools. Considering the characteristics of sand casting method, it is accepted as difficulty to improve the problems. In this study, it suggests shell mold method for mold instead of the machine work after the sand casting of the circle shape container product. And the surface accomplishes the following average of surface roughness Ra$9.94{\mu}m$ of machine work with the casting of flask mold by shell mold method. In accordance with the simplification of processing process and reducing the average thickness variation by mass production of product with detailed appearance, it has a good influence on safety accident prevention caused by production and damaged product. It is confirmed that making higher degree of size precision of all machine work product is possible to increase the safety and productivity, reduce the processing process and improve environment.

• Journal of the Korean Graphic Arts Communication Society
• /
• v.31 no.1
• /
• pp.51-64
• /
• 2013

When it comes to current growth trend for the printing process in Asia printing market, offset printing, gravure printing and screen printing are reduced respectively -4%, -19%, -55%. In judging from the fact, the change in the printing production system from mass production on small amount to small production on mass amount is the biggest issue. For this reason, digital printing shows the significant growth. According to the increase of the growth 78% for electro photography way and 67% for ink-jet, it's not enough to catch up with digital printing which is increasing as time goes by to equip with hardware like as digital press. There's been necessary to install the BOD(Book on Demand) system which is the advanced and regular publication edit solution based on web-to-print model in the prepress, and it has made the BOD system be considered in relation to maximization of efficiency and production. Therefore, this research tries to step forward from the POD concept, which is refired to "Print along with the ordered quantities, the ordered appropriate time and the demanded place", so that it could expand the range of the printing/publishing environment using the BOD system, the order-made publication based on automatically operating template. And it tried to make the relation to digital web press on ink-jet method which is adequate to "mass production on small amount" with such advanced concept. This research also aims to use actively BOD solution model to promote the productivity of labor, and then to produce the printings across all related industries, which means to manufacture maximally the products on the shortest time at minimum place through PC equipments.

• Journal of Microbiology and Biotechnology
• /
• v.23 no.10
• /
• pp.1445-1453
• /
• 2013

The scale-up criterion of constant oxygen mass transfer coefficient ($k_La$) was applied for the production of itaconic acid (IA) in a 50 L pilot-scale fermentor by the fungal cells of Aspergillus terreus. Various operating conditions were examined to collect as many $k_La$ data as possible by adjusting the stirring speed and aeration rate in both 5 L and 50 L fermentor systems. In the fermentations performed with the 5 L fermentor, the highest IA production was obtained under the operating conditions of 200 rpm and 1.5 vvm. Accordingly, we intended to find out parallel agitation and aeration rates in the 50 L fermentor system, under which the $k_La$ value measured was almost identical to that ($0.02sec^{-1}$) of the 5 L system. The conditions of 180 rpm and 0.5 vvm in the 50 L system turned out to be optimal for providing almost the same volumetric amount of dissolved oxygen (DO) into the fermentor, without causing shear damage to the producing cells due to excessive agitation. Practically identical fermentation physiologies were observed in both fermentations performed under those respective operating conditions, as demonstrated by nearly the same values of volumetric ($Q_p$) and specific ($q_p$) IA production rates, IA production yield ($Y_{p/s}$), and specific growth rate (${\mu}$). Specifically, the negligible difference of the specific growth rate (${\mu}$) between the two cultures (i.e., $0.029h^{-1}$ vs. $0.031h^{-1}$) was notable, considering the fact that ${\mu}$ normally has a significant influence on $q_p$ in the biosynthesis of secondary metabolites such as itaconic acid.

• Journal of Forest and Environmental Science
• /
• v.19 no.1
• /
• pp.48-68
• /
• 2003

There have been some problems of high labor. low productivity in the existing systems of bonsai cultivation. This study was conducted to cultivate a large quantity of hig-quality bonsai through the development of bottom irrigation system and management method. Bonsai placed on the FRP bed were grown very well by bottom irrigation system compared with direct watering and sprinkler system. It was concluded that bottom irrigation system was possible to reduce considerable manual labor and produce mass production of high-quality bonsai within shorter periods. This research was finally found that the growth was significantly better and earlier production was certain in the vinyl house, had another advantage which could cultivate less cold-resistant species and therefore broadened a range of species selection for market supply. Cultivation techniques by the use of vinyl house and bottom irrigation system developed was quite effective for early production of bonsai as well as for high productive and value added. This project developed a new practical techniques and systems which can make mass and early production of bonsai with high quality through input of less labor. Interest in bonsai is now expanding in landscape horticulture and other fields concerned, and bonsai export of our country is also increasing. Results from this research will make a great contribution to enhancing of bonsai cultivator's competitive position in world markets and to improving of their annual income.

• Journal of Environmental Science International
• /
• v.8 no.5
• /
• pp.575-586
• /
• 1999

From the environmental aspects, primary productivity of phytoplankton plays the most improtant role in enhancement of marine culture oyster production. This study may be divided into two branches; one is estimation of maximum oyster meat production per unit facility(Carrying Capacity) under the present enviromental conditions in Kamak Bay, the other is improvement of carrying from increase of primary productivity by changing the environmental conditions that cause not ot form an unfavorable environment such as the formation of oxygen deficient water mass using the eco-hydrodynamic model. By simulation of three-dimensional hydrdynamic model and ecosystem model, the comparison between observed and computed data showed good agreement. The results of sensitivity analysis showed that phytoplankton maximum growth rate was the most important parameter for phytoplankton and dissolved oxygen. The estimation of mean primary productivity of Wonpo, Kamak, Pyongsa, and Kunnae culture grounds in Kamak Bay during culturing period were 3.73gC/$m^2$/d, 2.12gC/$m^2$/d, 1.98gC/$m^2$/d, and 1.26gC/$m^2$/d, respectively. Under condition not ot form the oxygen deficient water mass, four times increasing of pollutants loading as much as the present loading from river increased mean primary productivity of whole culture grounds to 4.02gC/$m^2$/d. Sediment N, P fluxes that allowed for 35% increasing from the present conditions increased mean primary productivity of whole culture grounds to 3.65gC/$m^2$/d. Finally, ten times increasing of boundary loadings from the present conditions increased mean primary productivity of whole culture grounds to 3.95gC/$m^2$/d. The maximum oyster meat production per year and that of unit facility in actual oyster culture grounds under the present conditions were 6,929ton and 0.93ton, respectively. This 0.93ton/unit facility is considered to be the carrying capacity in study area, and if the primary productivity is increased by changing the environmental conditions, oyster production can be increased.

• International Journal of Precision Engineering and Manufacturing-Green Technology
• /
• v.9
• /
• pp.431-441
• /
• 2021

Gadolinium-doped ceria (GDC) is sought-after as an electrolyte layer in solid oxide fuel cells because of its high ionic conductivity and low treatment temperature. Recently, some studies have been reported to produce a component layer of solid oxide fuel cell using a Roll-to-Roll (R2R) system because of its characteristics of the cost-effective and eco-friendly advantages. However, the brittleness and low density of GDC prevent it from being mass-produced via the R2R continuous process. Therefore, we attempted to improve the density of GDC-based multi-electrolyte layers through an optimized R2R calendaring process. The finite element method was employed to determine suitable materials for the calendering rolls and the maximum calendering pressure that would reduce the thickness and porosity of the coated electrolyte layer without producing cracks in the layer. The effect of the number of calendering processes on the thickness and porosity of the electrolyte layers was examined as well. Silicon and steel were observed to be best-suited as the materials for the top and bottom rolls, respectively. Moreover, the maximum permissible calendering pressure was determined to be 15 MPa, while the ideal number of calendering processes was found to be 5. Experimental observations using scanning electron microscopy confirmed that the optimized calendering process reduced the thickness and porosity of the coated electrolyte layers by 16.99% and 7.04%, respectively. Thus, our findings suggest that large-area, high-density GDC-based multi-electrolyte layers with smooth surfaces can be produced via the R2R process, which can enable mass production of SOFCs.

• Journal of the Korea Safety Management & Science
• /
• v.2 no.4
• /
• pp.103-112
• /
• 2000

This research aims at the improvement of the manufacturing productivity of . kitchen furniture industry. W company deals with the orders of 2 types - the one is the batch order for mass production, and the other is the order of a customized single set. But, because the company has a single manufacturing system appropriate to mass production despite of the above 2 types-orders, the problems of increasing work-in-process, throughput time and material handling time were resulted in, and the overall productivity was generally low. We proposed a new material handling method to substitute the traditional one, the rearrangement of facility layout, and the introduction of a proper outsourcing method. This research results in about 80% increase in production quantity in the same period.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
• /
• 2001.10a
• /
• pp.185-189
• /
• 2001

In order to prevent the production defects the optimum design of product, jig and fixture putting in the field is very significant manufacturing method. Drilling Jig is the device according to industrial demand for multi manufacturing products on the growing at alarming rate. In the field of design and making for machine tool working, welding, assembling with jig and fixture for mass production is a specific division. They require analysis of many kinds of important factors, theory and practice of machine tool operating process and jig & fixture structure, machining condition for tool making, tool materials, heat treatment of jig & fixture components, know-how and so on. In this study we designed and constructed a drilling jig of mass production and performed tryout under the Auto CAD, Auto Lisp database, that we made by database, and window environment. Especially this study is reveals with the analysis of part drawing, jig planning, jig design etc, and then the result of drill jig's making try out.

• Journal of the Korean Society of Systems Engineering
• /
• v.11 no.1
• /
• pp.67-72
• /
• 2015

It has been tested for SW reliability in order to prevent the SW error during the development of weapons systems. According to a recent report, defects such as memory leak, buffer overflow, and null deference occur usually in the development stage, but also in the mass production stage. Although it is intended to enhance the SW test and evaluation to prevent SW failures in the development stage, the non-functional problems like syntax errors are not completely revised due to the limitation of the schedule and costs. In addition, SW failure rate are usually fluctuated by the operational environment through SW upgrade in contrast with HW. In this paper, we propose a method to increase SW reliability in the mass production stage of Korean weapon systems.