• KSBB Journal
• /
• 제11권6호
• /
• pp.704-711
• /
• 1996

경제성분석 기능을 가진 생물공정 flowsheeting 소프트웨어인 BioPro Designer를 이용하여 외부단 백질 생산 시스템의 최적 공정설계가 수행되었다. BioPro Designer를 이용하여 Salmonella phage P P22의 tailspike protein의 생산시스템에 적용되었 는데 최적공정을 선택하는 과정에서 투입되는 시간 과 노력에 획기척인 개선이 있었다. 숙주의 내부에 서 생산되는 외부 단백질의 folding 특성이 가장좋 은 생산시스템을 선택하는데 영향을 미 친다는 것을 보여주기위하여 wild type의 tailspike와 두개의 다른 변종 tailspike들, 즉 tsf G244→R과 Su A334 -V을 비교 검토되었다. 회수된 tailspike 단백질의 단위질량 대비 자본투자비를 비교 척도로 하여 최척 의 tailspike 생산 시스템이 선택되었다.

• 대한안전경영과학회지
• /
• 제15권4호
• /
• pp.179-184
• /
• 2013

An accident from machine work is often fatal to the worker. This accident is mostly preventable through perfect process jig. In case of this machine work, however, the disaster frequently occurred because of the design which is not considered the beginning of product design, post-process and mass process of production. As for sand casting method, this has the merits of the production; the product is easily produced by manual labor. On the other hand, this method has the demerits of a bigger dimensional error contrary to other mass process of production. When the sand casting product is in machine work, there are various problems such as unsafe fix and excessive cutting, product desorption and rapid life depreciation of equipment and tools. Considering the characteristics of sand casting method, it is accepted as difficulty to improve the problems. In this study, it suggests shell mold method for mold instead of the machine work after the sand casting of the circle shape container product. And the surface accomplishes the following average of surface roughness Ra$9.94{\mu}m$ of machine work with the casting of flask mold by shell mold method. In accordance with the simplification of processing process and reducing the average thickness variation by mass production of product with detailed appearance, it has a good influence on safety accident prevention caused by production and damaged product. It is confirmed that making higher degree of size precision of all machine work product is possible to increase the safety and productivity, reduce the processing process and improve environment.

• 한국인쇄학회지
• /
• 제31권1호
• /
• pp.51-64
• /
• 2013

When it comes to current growth trend for the printing process in Asia printing market, offset printing, gravure printing and screen printing are reduced respectively -4%, -19%, -55%. In judging from the fact, the change in the printing production system from mass production on small amount to small production on mass amount is the biggest issue. For this reason, digital printing shows the significant growth. According to the increase of the growth 78% for electro photography way and 67% for ink-jet, it's not enough to catch up with digital printing which is increasing as time goes by to equip with hardware like as digital press. There's been necessary to install the BOD(Book on Demand) system which is the advanced and regular publication edit solution based on web-to-print model in the prepress, and it has made the BOD system be considered in relation to maximization of efficiency and production. Therefore, this research tries to step forward from the POD concept, which is refired to "Print along with the ordered quantities, the ordered appropriate time and the demanded place", so that it could expand the range of the printing/publishing environment using the BOD system, the order-made publication based on automatically operating template. And it tried to make the relation to digital web press on ink-jet method which is adequate to "mass production on small amount" with such advanced concept. This research also aims to use actively BOD solution model to promote the productivity of labor, and then to produce the printings across all related industries, which means to manufacture maximally the products on the shortest time at minimum place through PC equipments.

• Journal of Microbiology and Biotechnology
• /
• 제23권10호
• /
• pp.1445-1453
• /
• 2013

The scale-up criterion of constant oxygen mass transfer coefficient ($k_La$) was applied for the production of itaconic acid (IA) in a 50 L pilot-scale fermentor by the fungal cells of Aspergillus terreus. Various operating conditions were examined to collect as many $k_La$ data as possible by adjusting the stirring speed and aeration rate in both 5 L and 50 L fermentor systems. In the fermentations performed with the 5 L fermentor, the highest IA production was obtained under the operating conditions of 200 rpm and 1.5 vvm. Accordingly, we intended to find out parallel agitation and aeration rates in the 50 L fermentor system, under which the $k_La$ value measured was almost identical to that ($0.02sec^{-1}$) of the 5 L system. The conditions of 180 rpm and 0.5 vvm in the 50 L system turned out to be optimal for providing almost the same volumetric amount of dissolved oxygen (DO) into the fermentor, without causing shear damage to the producing cells due to excessive agitation. Practically identical fermentation physiologies were observed in both fermentations performed under those respective operating conditions, as demonstrated by nearly the same values of volumetric ($Q_p$) and specific ($q_p$) IA production rates, IA production yield ($Y_{p/s}$), and specific growth rate (${\mu}$). Specifically, the negligible difference of the specific growth rate (${\mu}$) between the two cultures (i.e., $0.029h^{-1}$ vs. $0.031h^{-1}$) was notable, considering the fact that ${\mu}$ normally has a significant influence on $q_p$ in the biosynthesis of secondary metabolites such as itaconic acid.

• Journal of Forest and Environmental Science
• /
• 제19권1호
• /
• pp.48-68
• /
• 2003

현재 분재재배의 큰 문제점은 높은 노동력에 비해 생산성이 매우 낮은 것이다 본 연구는 관수시스템과 관리방법의 개발로 고품질의 분재를 대량생산하기 위해 실시되었다. FRP분상에서 재배된 분재는 직수관수나 스프링클러 관수에 비해 저변관수시스템에서 생육이 매우 좋았다. 또한 저면관수시스템은 노동력을 크게 줄일 수 있었고 짧은 기간에 대량생산을 할 수 있었다. 또한 비닐하우스내(內)에서 저면관수 시스템의 이용은 조기생산은 물론 고품질의 분재를 생산할 수 있었으며 내한성이 약한 수종들도 겨울재배가 가능하였다. 본 연구는 세계시장을 위한 국가경쟁력에 크게 기여하였을 뿐만 아니라 농가 수익에도 큰 도움을 줄 수 있었다.

• 한국환경과학회지
• /
• 제8권5호
• /
• pp.575-586
• /
• 1999

From the environmental aspects, primary productivity of phytoplankton plays the most improtant role in enhancement of marine culture oyster production. This study may be divided into two branches; one is estimation of maximum oyster meat production per unit facility(Carrying Capacity) under the present enviromental conditions in Kamak Bay, the other is improvement of carrying from increase of primary productivity by changing the environmental conditions that cause not ot form an unfavorable environment such as the formation of oxygen deficient water mass using the eco-hydrodynamic model. By simulation of three-dimensional hydrdynamic model and ecosystem model, the comparison between observed and computed data showed good agreement. The results of sensitivity analysis showed that phytoplankton maximum growth rate was the most important parameter for phytoplankton and dissolved oxygen. The estimation of mean primary productivity of Wonpo, Kamak, Pyongsa, and Kunnae culture grounds in Kamak Bay during culturing period were 3.73gC/$m^2$/d, 2.12gC/$m^2$/d, 1.98gC/$m^2$/d, and 1.26gC/$m^2$/d, respectively. Under condition not ot form the oxygen deficient water mass, four times increasing of pollutants loading as much as the present loading from river increased mean primary productivity of whole culture grounds to 4.02gC/$m^2$/d. Sediment N, P fluxes that allowed for 35% increasing from the present conditions increased mean primary productivity of whole culture grounds to 3.65gC/$m^2$/d. Finally, ten times increasing of boundary loadings from the present conditions increased mean primary productivity of whole culture grounds to 3.95gC/$m^2$/d. The maximum oyster meat production per year and that of unit facility in actual oyster culture grounds under the present conditions were 6,929ton and 0.93ton, respectively. This 0.93ton/unit facility is considered to be the carrying capacity in study area, and if the primary productivity is increased by changing the environmental conditions, oyster production can be increased.

• 대한안전경영과학회지
• /
• 제2권4호
• /
• pp.103-112
• /
• 2000

This research aims at the improvement of the manufacturing productivity of . kitchen furniture industry. W company deals with the orders of 2 types - the one is the batch order for mass production, and the other is the order of a customized single set. But, because the company has a single manufacturing system appropriate to mass production despite of the above 2 types-orders, the problems of increasing work-in-process, throughput time and material handling time were resulted in, and the overall productivity was generally low. We proposed a new material handling method to substitute the traditional one, the rearrangement of facility layout, and the introduction of a proper outsourcing method. This research results in about 80% increase in production quantity in the same period.

• 한국공작기계학회:학술대회논문집
• /
• 한국공작기계학회 2001년도 추계학술대회(한국공작기계학회)
• /
• pp.185-189
• /
• 2001

In order to prevent the production defects the optimum design of product, jig and fixture putting in the field is very significant manufacturing method. Drilling Jig is the device according to industrial demand for multi manufacturing products on the growing at alarming rate. In the field of design and making for machine tool working, welding, assembling with jig and fixture for mass production is a specific division. They require analysis of many kinds of important factors, theory and practice of machine tool operating process and jig & fixture structure, machining condition for tool making, tool materials, heat treatment of jig & fixture components, know-how and so on. In this study we designed and constructed a drilling jig of mass production and performed tryout under the Auto CAD, Auto Lisp database, that we made by database, and window environment. Especially this study is reveals with the analysis of part drawing, jig planning, jig design etc, and then the result of drill jig's making try out.

• 시스템엔지니어링학술지
• /
• 제11권1호
• /
• pp.67-72
• /
• 2015

It has been tested for SW reliability in order to prevent the SW error during the development of weapons systems. According to a recent report, defects such as memory leak, buffer overflow, and null deference occur usually in the development stage, but also in the mass production stage. Although it is intended to enhance the SW test and evaluation to prevent SW failures in the development stage, the non-functional problems like syntax errors are not completely revised due to the limitation of the schedule and costs. In addition, SW failure rate are usually fluctuated by the operational environment through SW upgrade in contrast with HW. In this paper, we propose a method to increase SW reliability in the mass production stage of Korean weapon systems.

• 한국해양공학회:학술대회논문집
• /
• 한국해양공학회 2000년도 춘계학술대회 논문집
• /
• pp.104-108
• /
• 2000

Drilling Jig is the device according to industrial demand for multi manufacturing products on the growing at alarming rate. In the field of design and making for machine tool working, welding, assembling with jig and fixture for mass production is a specific division. In order to prevent the production defects the optimum design of product, fig and fixture putting in the field is very significant manufacturing method. They require analysis of many kinds of important factors, theory and practice of machine tool operating process and its phenomena, jig & fixture structure, machining condition for tool making tool materials, heat treatment of jig & fixture components, know-how and so on. In this study we designed and constructed a drilling jig of mass production and performed tryout under the Auto CAD, database, and window environment. Especially Part1 of this study is reveals with the analysis of part drawing, jig planning, jig design etc.