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Note on Stochastic Inequalities

  • Jeon, Jong-Woo
    • Journal of the Korean Statistical Society
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    • v.9 no.2
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    • pp.121-125
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    • 1980
  • In this note, we establish a result which characterizes a partial ordering of probability distributions on a partially ordered space by that of conditional distributions. This result is then reduced to prove the conjecture made by Nevius, Proschan and Sethuraman (1977).

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ATF3 Mediates Anti-Cancer Activity of Trans-10, cis-12-Conjugated Linoleic Acid in Human Colon Cancer Cells

  • Kim, Kui-Jin;Lee, Jihye;Park, Yeonhwa;Lee, Seong-Ho
    • Biomolecules & Therapeutics
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    • v.23 no.2
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    • pp.134-140
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    • 2015
  • Conjugated linoleic acids (CLA) are a family of isomers of linoleic acid. CLA increases growth arrest and apoptosis of human colorectal cancer cells through an isomer-specific manner. ATF3 belongs to the ATF/CREB family of transcription factors and is associated with apoptosis in colorectal cancer. The present study was performed to investigate the molecular mechanism by which t10, c12-CLA stimulates ATF3 expression and apoptosis in human colorectal cancer cells. t10, c12-CLA increased an apoptosis in human colorectal cancer cells in dose dependent manner. t10, c12-CLA induced ATF3 mRNA and luciferase activity of ATF3 promoter in a dose-dependent manner. The responsible region for ATF3 transcriptional activation by t10, c12-CLA is located between -147 and -1850 of ATF3 promoter. mRNA stability of ATF3 was not affected by t10, c12-CLA treatment. t10, c12-CLA increases $GSK3{\beta}$ expression and suppresses IGF-1-stimulated phosphorylation of Akt. The knockdown of ATF3 suppressed expression of $GSK3{\beta}$ and NAG-1 and PARP cleavage. The results suggest that t10, c12-CLA induces apoptosis through ATF3-mediated pathway in human colorectal cancer cells.

AN EXPERIMENTAL STUDY ON THE FILM THICKNESS OF RESIN LUTING CEMENTS (치과용 레진 시멘트의 피막도에 관한 실험적 연구)

  • Cho Kook-Hyeon;Song Chang-Yong;Song Kwang-Yeob;Park Chan-Woon
    • The Journal of Korean Academy of Prosthodontics
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    • v.32 no.2
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    • pp.212-224
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    • 1994
  • The purpose of this study was to evaluate and compare film thickness of five kinds of resin luting cements [Comspan, Panavia Ex, Maryland bridge adhesive, All-bond C & B cementation kit, and Super-bond C & B]. Zinc-phosphate cement and glass-ionomer cement were used as the control group. In order to measure the film thickness the methods used were in broad compliance with ADA Specification No. 8, a tapered-die system that simulates clinical conditions more closely, and the connected tapered-die system that simulates bridge conditions. The inorganic filler size of resin cements was also examined with scanning electron micrographs. The results were obtained as follows ; 1. The film thickness of resin cements was increased in the order of Comspan, Panavia Ex, Super-bond C & B, Maryland bridge adhesive, and All-bond C & B cementation kit. Maryland bridge adhesive and All-bond C & B cementation kit showed significantly higher film thickness than the control group(p<0.01). 2. For all resin cements, there was a significant difference of film thickness between the ADA method and the tapered-die system. Generally, the tapered-die system demonstrated lower film thickness than the ADA method(p<0.01). 3. There was no significant difference in film thickness between the tapered-die system and the tapered-die bridge system in all resin cements(p<0.01). 4. The scanning electron microscope showed that the cement with larger filler had a tendency to be higher in film thickness.

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Disparity in opinions on lip protrusiveness in contemporary African American faces

  • Battle, Yvette;Schneider, Monica;Magder, Laurence;Pae, Eung-Kwon
    • The korean journal of orthodontics
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    • v.48 no.1
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    • pp.23-29
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    • 2018
  • Objective: In accordance with the changing demographics in the United States, orthodontists working on various ethnic populations should be more conscious when using the standardized profile analyses for the African American patient. The objective of this study was to examine whether the perception of lip protrusiveness in modern African American faces has changed. For this purpose, we investigated the most favorable African American lip profile using the opinions of 10 experienced and 10 newly trained younger orthodontists. Methods: Attractiveness was converted to a number on visualized analog scales. Comparative ranks on 16 African American profiles, with focus on lip protrusiveness and thickness, were made among the groups. Mixed-effects linear regression models were fit and group differences were estimated. Results: Younger orthodontists favored a more protrusive lip profile, and the variance in their perceptions was narrower than those of older orthodontists. Measurements related to upper lip protrusion showed the strongest correlation to attractiveness (r = -0.82). The association with attractiveness decreased linearly as the protrusiveness of the upper lip increased. Steiner's E-line was the most influential reference for determining the level of attractiveness for the older orthodontists, whereas upper lip protrusion was the most influential factor for the young orthodontists. Conclusions: An adequate level of lip protrusiveness and thickness should be essential for maintaining attractive esthetics in African American patients. Yet, a new set of standards for prominent lips in this population is necessary to reflect the current trend in the concept of a beautiful face in the modern world.

Characterization of rapidly consolidated γ-TiAl

  • Kothari, Kunal;Radhakrishnan, Ramachandran;Sudarshan, Tirumalai S.;Wereley, Norman M.
    • Advances in materials Research
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    • v.1 no.1
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    • pp.51-74
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    • 2012
  • A powder metallurgy-based rapid consolidation technique, Plasma Pressure Compaction ($P^2C^{(R)}$), was utilized to produce near-net shape parts of gamma titanium aluminides (${\gamma}$-TiAl). Micron-sized ${\gamma}$-TiAl powders, composed of Ti-50%Al and Ti-48%Al-2%Cr-2%Nb (at%), were rapidly consolidated to form near-net shape ${\gamma}$-TiAl parts in the form of 1.0" (25.4 mm) diameter discs, as well as $3"{\times}2.25"$ ($76.2mm{\times}57.2mm$) tiles, having a thickness of 0.25" (6.35 mm). The ${\gamma}$-TiAl parts were consolidated to near theoretical density. The microstructural morphology of the consolidated parts was found to vary with consolidation conditions. Mechanical properties exhibited a strong dependence on microstructural morphology and grain size. Because of the rapid consolidation process used here, grain growth during consolidation was minimal, which in turn led to enhanced mechanical properties. Consolidated ${\gamma}$-TiAl samples corresponding to Ti-48%Al-2%Cr-2%Nb composition with a duplex microstructure (with an average grain size of $5{\mu}m$) exhibited superior mechanical properties. Flexural strength, ductility, elastic modulus and fracture toughness for these samples were as high as 1238 MPa, 2.3%, 154.58 GPa and 17.95 MPa $m^{1/2}$, respectively. The high temperature mechanical properties of the consolidated ${\gamma}$-TiAl samples were characterized in air and vacuum and were found to retain flexural strength and elastic modulus for temperatures up to $700^{\circ}C$. At high temperatures, the flexural strength of ${\gamma}$-TiAl samples with Ti-50%Al composition deteriorated in air by 10% as compared to that in vacuum. ${\gamma}$-TiAl samples with Ti-48%Al-2%Nb-2%Cr composition exhibited better if not equal flexural strength in air than in vacuum at high temperatures.

Image Processing Software Development for Detection of Oyster Hinge Lines (굴의 힌지 선 감지를 위한 영상처리 소프트웨어의 개발)

  • So, J.D.;Wheaton, Fred W.
    • Journal of Biosystems Engineering
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    • v.22 no.2
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    • pp.237-246
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    • 1997
  • Shucking(removing the meat from the shell) an oyster requires that the muscle attachments to the two shell valves and the hinge be severed. Described here is the computer vision software needed to locate the oyster hinge line so it can be automatically severed, one step in development of an automated oyster shucker. Oysters are first prepared by washing and trimming off a small shell piece on the oyster hinge end to provide access to the outer hinge surface. A computer vision system employing a color video comera then gabs an image of the hinge end of the oyster shell. This image is Processed by the computer using software. The software is a combination of commercially available and custom written routines that locate the oyster hinge. The software uses four feature variables, circularity, rectangularity, aspect-ration, and Euclidian distance, to distinguish the hinge object from other dark colored objects on the hinge end of the oyster. Several techniques, including shrink-expand, thresholding, and others, were used to secure an image that could be reliably and efficiently processed to locate the oyster hinge line.

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