• 한국컴퓨터정보학회논문지
• /
• 제27권10호
• /
• pp.175-184
• /
• 2022

이 연구는 노인여성을 대상으로 수중(AZ)과 지상(ZG) 환경에서의 댄스운동이 골대사지표(BMM)와 골밀도(BMD)에 미치는 효과를 분석하여 골다공증 및 골감소증 예방을 위한 효율적인 운동방법을 제안하고자 실시되었다. 연구의 대상자는 70대 이상의 노인여성을 대상으로 수중댄스그룹(AZG, n=11), 지상댄스그룹(ZGG, n=13), 통제그룹(CG, n=12)을 무작위로 배정하였으며, 12주간 주 2회 60분씩 댄스운동을 실시하였다. 이 연구의 결과 OC은 AZG(P<.001)과 ZGG(P<.05), IGF-1은 AZG(P<.01)에서 유의하게 증가하였고 DPD, BMD, T-score는 유의한 차이가 나타나지 않았다. 따라서 수중과 지상에서의 댄스(Zumba) 운동이 노인여성의 BMM와 BMD 긍정적인 효과가 나타나 골다공증, 골감소증을 지연시킬 수 있는 효율적인 중재방법으로 제안한다.

• Imaging Science in Dentistry
• /
• 제37권3호
• /
• pp.171-180
• /
• 2007

The role of radiographic imaging in determining the size, numbers and the position of implants is very important. To perform the implant procedure, the dentist needs to evaluate the bone pathology and bone density, and to know the precise height, width, and contour of the alveolar process, as well as its relationship to the maxillary sinus and mandibular canal. The author analyzed 3 implant cases for treatment planning with the cone beam CT. All axial, panoramic, serial and buccolingual-sectioned images of 3 cases with stent including vertical marker were taken by using Mercuray (Hitachi, Japan). When the curved line drawn intentionally did not include dot image of a vertical marker on the axial image of CBCT, the image of the vertical marker was deformed on its buccolingually sectioned image. There was wide discrepancy in inclination between the alveolar bone and tooth on buccolingually sectioned image.

• Asian-Australasian Journal of Animal Sciences
• /
• 제19권12호
• /
• pp.1702-1705
• /
• 2006

A simulation study was conducted to evaluate a fine-mapping method exploiting population-wide linkage disequilibrium. Data were simulated according to the pedigree structure based on a large paternal half-sib family population with a total of 1,034 or 2,068 progeny. Twenty autosomes of 100 cM were generated with 5 cM or 1 cM marker intervals for all founder individuals in the pedigree, and marker alleles and a number of quantitative trait loci (QTL) explaining a total of 70% phenotypic variance were generated and randomly assigned across the whole chromosomes, assuming linkage equilibrium between the markers. The founder chromosomes were then descended through the pedigree to the current offspring generation, including recombinants that were generated by recombination between adjacent markers. Power to detect QTL was high for the QTL with at least moderate size, which was more pronounced with larger sample size and denser marker map. However, sample size contributed much more significantly to power to detect QTL than map density to the precise estimate of QTL position. No QTL was detected on the test chromosomes in which QTL was not assigned, which did not allow detection of false positive QTL. For the multiple QTL that were closely located, the estimates of the QTL positions were biased, except when the QTL were located on the right marker positions. Our fine mapping simulation results indicate that construction of dense maps and large sample size is needed to increase power to detect QTL and mapping precision for QTL position.

• 한국유전체학회:학술대회논문집
• /
• 한국유전체학회 2004년도 The 13th Korea Genome Conference
• /
• pp.46.2-46.2
• /
• 2004

• 약학회지
• /
• 제49권1호
• /
• pp.44-50
• /
• 2005

The purpose of this study was to investigate the relationship between Trp64Arg polymorphism in the ${\beta}_3$-adrenergic receptor gene and complex phenotypes such as blood pressure, body compositions and bone parameters in young men about 20 years, and to collect the fundamental data in designing the exercise program. Eighty healthy young men including 41 controls and 39 athletes were recruited, Trp64Arg polymorphism in the ${\beta}_3$-adrenergic receptor gene was genotyped by PCR-RFLP method. By association study, there were no significance in genotype and allele frequencies of Trp64Arg polymorphism in the ${\beta}_3$-adrenergic receptor gene between controls and athletes, respectively (p>0.05). When the relationship between physiological parameters and Trp64Arg polymorphism in the ${\beta}_3$-adrenergic receptor gene was tested, this polymorphism was significantly associated with 3th lumber and left femoral neck Z-score values in controls (p<0.05), but these associations were not detected in athletic groups (p>0.05). It is likely that Trp64Arg polymorphism in the ${\beta}_3$-adrenergic receptor gene is a genetic marker for the bone mineral density index in young men, but environmental factors such as exercise modify the significant effect of this polymorphism. Thus, our results suggest that Trp64Arg polymorphism in the ${\beta}_3$-adrenergic receptor gene may be applicable as a predictive marker for osteoporosis in Korean young men, and regular exercise may prevent the disadventageous effect of this polymorphism for bone mineral density in male athletic group.

• Journal of Ship and Ocean Technology
• /
• 제8권2호
• /
• pp.61-69
• /
• 2004

Unsteady nonlinear wave motions on the free surface over a plane beach of constant slope are numerically simulated using a finite difference method in rectangular grid system. Two-dimensional Navier-Stokes equations and the continuity equation are used for the computations. Irregular leg lengths and stars are employed near the boundaries of body and free surface to satisfy the boundary conditions. Also, the free surface which consists of markers or segments is determined every time step with the satisfaction of kinematic and dynamic free surface conditions. Moreover, marker-density method is also adopted to allow plunging jets impinging on the free surface. The second-order Stokes wave theory is employed for the generation of waves on the inflow boundary. For the simulation of wave breaking phenomena, the computations are carried out with the plane beach of constant slope in surf zone. The results are compared with other existing experimental results. Agreement between the experimental data and the computation results is good.

• 한국해양공학회지
• /
• 제19권3호
• /
• pp.18-24
• /
• 2005

Wave overtopping is one of the most important processes for the design of seawalls. The term "wave overtopping" is used here to refer to the processes where waves hit a sloping structure run up the slope and, if the crest level of the slope is lower than the highest run up level, overtop the structure. Wave overtopping is dependent on the processes associated with breaking wave. A numerical model based on Navier-Stokes equation and the Marker-density function for predicting wave overtopping of coastal structures is developed in this paper. In order to evaluate the present model, two simulations are tested. One is overflow without waves at vertical seawall, and the other is wave overtopping at sloping seawalls.

• Asian-Australasian Journal of Animal Sciences
• /
• 제24권4호
• /
• pp.457-462
• /
• 2011

The purpose of this study was to detect QTL for carcass quality on bovine chromosome (BTA) 6 using a high density SNP map in a Hanwoo population. The data set comprised 45 sires and their 427 Hanwoo steers that were born between spring of 2005 and fall of 2007. The steers that were used for progeny testing in the Hanwoo Improvement Center in Seosan, Korea, were genotyped with the 2,535SNPs on BTA6 that were embedded in the Illumina bovine SNP 50K chip. Four different linkage disequilibrium (LD) mapping models were applied to detect significant SNPs for carcass quality traits; the fixed model with a single marker, the random model with a single marker, the random model with haplotype effects using two adjacent markers, and the random model at hidden state. A total of twelve QTL were detected, for which four, one, three and four SNPs were detected on BTA6 under the respective models (p<0.001). Among the detected QTL, four, two, five and one QTL were associated with carcass weight, backfat thickness, longissimus dorsi muscle area, and marbling score, respectively (p<0.001). Our results suggest that the use of multiple LD mapping approaches may be beneficial in increasing power to detect QTL given a limited sample size and magnitude of QTL effect.

• 대한조선학회논문집
• /
• 제47권2호
• /
• pp.188-195
• /
• 2010

Green water load is an important parameter to be considered in designing a modern ship or offshore structures like FPSO and FSRU. In this research, a numerical simulation method for green water phenomenon is introduced. The Navier-Stokes equations and the continuity equation are used as governing equations. The equations are calculated using Finite Difference Method(FDM) in rectangular staggered grid system. To increase the numerical accuracy near the body, the Cartesian cut cell method is employed. The nonlinear free-surface during green water incident is defined by Marker-density method. The green waters on a box in regular waves are simulated. The simulation results are compared with other experimental and computational results for verification. To check the applicability to moving ship, the green water of the ship which is towed by uniform force in regular wave, is simulated. The ship is set free to heave and to surge.

• 한국해양공학회:학술대회논문집
• /
• 한국해양공학회 2004년도 학술대회지
• /
• pp.90-95
• /
• 2004

During the past 50 years methods for predicting wave overtopping of coastal structures have coastal structures have continuously been developed Wave overtopping is one of the most important processes for the design of seawalls. The term 'wave overtopping' is used here to refer to the processes where waves hit a sloping structure run up the slope and, if the crest level of the slope is lower than the highest run up level, overtop the structure. Wave overtopping is dependent on the processes associated with breaking wave. The Numerical model is based on Navier-Stokes equation and Marker-Density Function of method for nonlinear free-surface flow by Miyata & Park(1995). The influence of how the slopes of seawalls, wave type and crest freeboard affect overtopping discharges has been investigated. The research of study using the new development nonlinear free-surface flow numerical model SOLA-VOF are presented.