• 한국어병학회지
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• 제21권3호
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• pp.241-246
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• 2008

The effects of temperatures on pearl oyster, Pincdata fucata were studied by evaluating some functional immune responses of the haemocytes. Water temperature is one of the most important factors in bivalve immune defense. Haemocytes comprise a primary line by inflammation, encapsulation and phagocytosis. These phagocytic abilities of haemocytes were observed in different temperatures. The number of the circulating haemocytes by migratory assay, phagocytic activities by MTT assay and reactive oxygen species production of haemocytes by CL assay were measured at different temperatures. Results showed that pearl oyster maintained at 20℃ and 25℃ displayed significantly higher values for all the measured immune parameters in comparison to maintained at 10, 15, and 30℃.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2000년도 추계학술발표대회 및 bio-venture fair
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• pp.137-140
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• 2000

Numerous novel marine natural products have been discovered and isolated from varied marine organisms by the diligent bio-prospectors over the past decades. An assessment of the current status of commercial development of these natural compounds indicates only minimal commercialization due to the lack of sustainable supply. To bridge the gaps between discovery and commercialization of these tantalizing bioactive compounds, marine bioprocess engineering is the key for its success. The problems, challenges and opportunities for marine bioprocess engineers are examined for the timely transformation of the discovery into commercial reality. Marine bioprocess engineers will find it the most rewarding practice of their expertise in diving into the ocean.

• 한국해양바이오학회지
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• 제13권1호
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• pp.20-27
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• 2021

Ironically, marine bioresource production in Chungnam Province is the second-largest in the country. The province's marine bioresource production puts its lack of a marine bioindustry in the spotlight despite the region's favorable conditions to produce representative value-added and (ultra) high value-added products such as neutraceutical and/or pharmaceutical function. This juxtaposition is to be expected, as there are no institutions for training professionals in the field of marine biology or in the fisheries industry in the West Sea area. The unique features of the region require individuals with specialized training who have been educated in accordance with regional development and the specificity of the region. Recently, however, a plan has been initiated at the national level to foster the growth of the marine biology industry in the Chungnam Province on Korea's west coast. This plan includes increasing funds to the marine biology market to 1.2 trillion by 2030. If the Chungnam region wants to successfully revitalize the marine biology industry and put the increased funds to efficient use, it must first establish various research and (business) development (R&(B)D) plans regarding local marine biology infrastructures and marine biology programs at local universities. It must also focus on training specialists to protect, maintain, and develop the region's marine bio-resources to increase the growth of the region's bioindustry.

• 해양환경안전학회지
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• 제29권3호
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• pp.270-280
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• 2023

The creation of marine protected areas is an important aspect of marine ecosystem sustainability. However, South Korea has not achieved its Aichi Biodiversity Target to designate 10% of its sea as marine protected by 2020. Local residents have strong opposition to the designation of protected areas in South Korea; there has been little trust in the government since the 1970s, when residents felt that their property rights were being ignored in favor of creating national parks. Here, we present a case where creation of a marine protected area was led by residents of TongYeong City. The success of a participation income project to remove marine debris in the city seems to be an important factor that led to the designation of the marine protected area. The case of TongYeong City is compared with that of nearby Geoje City, where an ecologically important stream has not been designated as a wetland protection area, although a similar participation income project enrolled the city's residents. The comparison provides a tentative assessment of the conditions needed to increase trust among residents. The results suggest that, if the projects are well-designed and well-managed, participation income projects to remove marine debris can be effective in building trust among stakeholders in potential marine protected areas.

• Ocean and Polar Research
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• 제39권1호
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• pp.13-21
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• 2017

Temporal changes in the number of zooplankton species are important information for understanding basic characteristics and species diversity in marine ecosystems. The aim of the present study was to estimate the optimal monitoring frequency (OMF) to guarantee and predict the minimum number of species occurrences for studies concerning marine ecosystems. The OMF is estimated using the temporal number of zooplankton species through bi-weekly monitoring of zooplankton species data according to operational taxonomic units in the Tongyoung coastal sea. The optimal model comprises two terms, a constant (optimal mean) and a cosine function with a one-year period. The confidence interval (CI) range of the model with monitoring frequency was estimated using a bootstrap method. The CI range was used as a reference to estimate the optimal monitoring frequency. In general, the minimum monitoring frequency (numbers per year) directly depends on the target (acceptable) estimation error. When the acceptable error (range of the CI) increases, the monitoring frequency decreases because the large acceptable error signals a rough estimation. If the acceptable error (unit: number value) of the number of the zooplankton species is set to 3, the minimum monitoring frequency (times per year) is 24. The residual distribution of the model followed a normal distribution. This model can be applied for the estimation of the minimal monitoring frequency that satisfies the target error bounds, as this model provides an estimation of the error of the zooplankton species numbers with monitoring frequencies.

• 대한통합의학회지
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• 제10권4호
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• pp.121-136
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• 2022

Purpose : Marine therapy is an activity that promotes public health such as constitution improvement, immunity improvement, and anti-aging by utilizing marine therapeutic resources such as seawater, mud, seaweed, salt and sea climate. In Europe developed countries, the marine therapy industry has been developing for centuries, with France, Germany, and Israel leading the way. Currently, it has achieved great industrial achievements and is of great help in improving the human health. The purpose of this study is to investigate how marine therapeutic resources benefit to human health, as well as how to study and utilize their efficacy. We analyzed previous research articles related to the effects of marine therapeutic resources. Methods : The study included a total of 830 published literatures in the last 20 years from the Republic of Korea and other contries. PubMed and Google Scholar were utilized to collect the foreign source while the local scientific publications were accessed through the Korean Education and research Information Service (KERIS) and Korean studies Information Service System (KISS). The keywords used to search foreign literature were "marine therapy", "Thalassotherapy", "seawater", "deep seawater", "saline groundwater", "sand therapy", "mud therapy", "hydrotherapy", "seaweed", "Sun light", "sea salt", "marine animal", and "marine microorganisms" were combined, and for the domestic literature, the keywords were "marine therapy", "marine therapeutic resources", "seawater", and "sand". Results : A total of 830 research papers were found as a result of searching for domestic and international papers related to marine therapeutic resources. The collected documents were classified into 175 seawater resources, 259 marine mineral resources, 41 marine environment, and 355 marine organisms. The efficacy of each marine therapeutic resources was analyzed. By resources type, there were about 213 papers on the efficacy of seaweed, followed by about 175 papers on seawater, 142 on microorganisms, 124 on mud/peat, and sand, salt, minerals and others are appeared in order (Table 1). Conclusion : Korea has the highest marine biodiversity index, excellent tidal flats, four distinct seasons, and various sea environments of the East sea, Yellow sea, South sea and Jeju sea. For this reason, Korea has a much more diverse marine therapeutic resources than other advanced countries in the marine therapy industry. prebiously, we thought that the sea was only valuable as a shipping port and fishery industry. But now, it been shown that the ocean can become a new industrial field which can contribute to human health and well-being by providing healing and therapy to people through the gift of marine resources.

• 해양환경안전학회지
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• 제27권7호
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• pp.967-976
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• 2021

우리나라에서 발생한 최근 10년간의 해양사고를 살펴보면 다른 종류의 사고에 비하여 해양 부유물에 의한 해양사고가 뚜렷하게 증가하고 있는 것을 알 수 있다. 본 연구에서는 연간 발생한 해양사고에 대한 중앙해양안전심판원과 해양경찰청의 통계연보를 분석하고 비교 검토해보았다. 두 기관의 통계는 일부 상이한 부분이 있었지만 전체 해양사고 통계 중 부유물 해양사고의 수치는 지속적으로 증가하고 있었고 어선과 비어선으로 나누었을 때 어선에서 특히 많이 발생하고 있다는 것을 알 수 있었다. 또한 부유물 감김 해양사고의 원인이 되는 주된 부유물질은 어망, 어구, 밧줄류에 기인한 비율이 압도적으로 많았다. 해양 플라스틱과 관련된 국내외 정책들을 들여다보면 대부분 해양오염 자체를 예방하고 해양쓰레기를 회수하는데 집중하여 해양환경적인 문제로 인식하고 있는 것이 대부분이다. 또한 해양환경 및 해양 쓰레기와 관련된 대표적인 법인 「해양환경관리법」과 「해양폐기물 및 해양오염퇴적물 관리법」을 살펴보면 해양쓰레기를 해양폐기물의 한 종류로써 인식하고 있으며 폐기물의 종류와 정의는 다루되, 해양쓰레기에 관한 정의는 찾아보기 어려웠다. 따라서 본 연구에서는 선박의 운항에 영향을 미칠 수 있는 해양 플라스틱 쓰레기 규제와 관련된 법제도를 살펴보고 개선방안을 제시해 보고자 하였다. 그리고 선박의 안전한 항행과 운항에 적합한 해양 쓰레기에 관한 정의가 부재하기에 이에 맞는 해양쓰레기의 범위를 제안하여 그 개념을 명확히 해보고자 하였다.

• Archives of Pharmacal Research
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• 제28권9호
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• pp.1042-1046
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• 2005

Two known modified dipeptides, trichodermamide A (1) and aspergillazine A (2), were isolated from an ethyl acetate extract of the metabolite of a marine-derived fungus Spicaria elegans, and were found to have a weak cytotoxic effect on three cancer cell lines P388, A-549, and HL-60 agreed. To our knowledge, this is the first report on the isolation of compounds 1 and 2 from the fungus Spicaria elegans and their cytotoxic effect.

• 통합자연과학논문집
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• 제4권4호
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• pp.255-265
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• 2011

Marine ecosystems are often characterized by a high biological diversity, and it corresponds to a high chemical diversity. Up to present, more than 20,000 new bioactive substances have been isolated from marine organisms, where considerable numbers of these naturally occurring derivatives are developed as potential candidates for pharmaceutical application. In this process, screening of natural products from marine organisms that could potentially inhibit the expression of metalloproteinases has gained a huge popularity. Cancer is considered as one of the deadliest diseases in the medical field. Matrix metalloproteinase (MMPs) can degrade extracellular matrix (ECM) components and play important roles in a variety of biological and pathological processes. Matrix metalloproteinase inhibitors (MMPIs) have been identified as potential therapeutic candidates for metastasis, arthritis, chronic inflammation and wrinkle formation.

• 해양환경안전학회:학술대회논문집
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• 해양환경안전학회 2017년도 공동학술발표회
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• pp.217-217
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• 2017