• Title/Summary/Keyword: Marginal zone

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Immunohistochemistry of Glucagon- immunoreactive Cells in the Developing Pancreas of the Korean Native Goat (Capra hircus)

  • Sae-Kwang Ku;Hyeung-Sik Lee;Jae-Hyun Lee
    • Animal cells and systems
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    • v.3 no.2
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    • pp.187-191
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    • 1999
  • The distribution of glucagon-immunoreactive cells in the pancreas during various developmental stages (fetus, neonate, 1-month-old, 6-month-old and adult) of the Korean native goat was investigated by immunohistochemical methods. The varying distribution and frequency of glucagon-immunoreactive cells in the pancreas of the Korean native goat were observed. The glucagon-immunoreactive cells were detected in both exocrine and endocrine portions (pancreatic islets) at all developmental stages and also in ducts of the 6-month-old and adult. The relative frequencies of glucagon-immunoreactive cells increased in the pancreatic islets and ducts with age, but decreased in the exocrine portions. Generally, they were distributed in the interacinar spaces or marginal zone of the pancreatic islets during all stages of development. However, the cell distributions of the pancreatic islets in the neonate divided into two types: 1) ones which were distributed in the inner zone, and 2) others in the peripheral zone.

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A Study on the Evaluation of Head Restraint System in Domestic Cars (국내생산차량의 시트 머리구속장치 평가에 관한 연구)

  • 조휘창;박인송;김영은
    • Transactions of the Korean Society of Automotive Engineers
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    • v.12 no.1
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    • pp.99-105
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    • 2004
  • The car seat head restraint is used for neck injury(whiplash injury) prevention in rear end impacts. The purpose of this study was to evaluate the seat head restraints for the total number of 34 domestic cars. H-POINT machine and HRMD(head restraint measuring device) were applied to measure backset(the distance between head and seat head restraint) and height(height gap between head and seat head restraint). For tendency study of driver's head position, we took the 320 driver's pictures in the street. As results, There were only five percent drivers in good and acceptable zone. For car seat head restraint system, the results was 9 cars for good zone, 10 cars for acceptable zone, 9 cars for marginal zone and 6 cars for poor zone were evaluated. For a precise evaluation the of whiplash injury, detailed FE neck model will be developed and the clinical database should be constructed for model validation.

Petrogenesis of the Skarn at the Dielette, Cotentin, France (디엘레트지역(地域) 스카른의 암석학적(岩石學的) 성인연구(成因硏究))

  • Chang, Ho Wan
    • Economic and Environmental Geology
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    • v.18 no.2
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    • pp.139-150
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    • 1985
  • Skarn at the Dielette formed largely in calc-silicate hornfels at the contact with the Flamanville granite. The skarn consists mainly of garnet and pyroxene, and less frequently vesuvianite. Traversing toward calc-silicate hornfels wall rock from a central zone of the skarn, the general sequence of formation of mineral assemblages is: (1) dark brown garnet (2) pale brown garnet-vesuvianite-pyroxene, and (3) pyroxene-prehnite-scapolite-wollastonite envelopes (designated as transition zone) developed between skarn and calc-silicate hornfels. The central zone of the skarn consists mainly of dark brown garnets (garnet I) that contain little or no pyroxene. The pale brown garnet (garnet II) is associated with pyroxene and vesuvianite. The sequence of these garnets results from the zonal growth outward. There is an abrupt discontinuity in composition between garnet I formed in early stage and garnet II in late stage, while each garnet shows relatively uniform composition. At the zone in contact with the granite, the iron contents of garnets decrease toward the marginal zone of the skarn, from an average value of 36 mole % andradite in garnet I to 18 mole % andradite in garnet II. At the zone distant from the granite, the andradite component decreases from 28 mole % in garnet 1 to 19 mole % in garnet II. The variation of the iron contents of pyroxenes is also similar to that of garnets. The sharp discontinuity in composition of garnets and pyroxenes suggests that the skarn of study area was formed by infiltration metasomatic process. The results of the analyses of mineral assemblages of the transition zone by chemical potential diagrams suggest that the transition zone was made by the diffusion of the elements Ca, K and Fe from the skarn to the calc-silicate hornfels contact zone. The estimated temperatures and $Xco_2$ for the formation of the transition zone show $300^{\circ}C$$440^{\circ}C$ and $0.07{\pm}0.05<Xco_2<0.02{\pm}0.01$ at 1 Kb respectively.

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A Case Report of Disseminated Extranodal Marginal Zone B-Cell Lymphoma of MALT Manifested by Solitary Pulmonary Nodule (고립성 폐결절로 발현한 파종성 림프절 외 변연부 B-세포 림프종 1예)

  • Cho, Joon Hyun;Jung, Jong Pil;Cha, Hee Jeong;Park, Chang Ryul;Kim, Sung Ryul;Kim, Hawk;Park, Jin Woo;Woo, Soon Joo;Eum, Eun A;Lee, Ki Young;Jegal, Yang Jin
    • Tuberculosis and Respiratory Diseases
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    • v.61 no.2
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    • pp.171-177
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    • 2006
  • Extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) is usually indolent. Although it was reported recently that about 20-30% cases of MALT lymphoma presented with a disseminated disease at diagnosis, it was described as a disease localized at diagnosis and remaining stable for a prolonged period. However, only a few cases of MALT lymphoma involved the lung and gastrointestinal tract all at once. We report a case of a 73-year-old man with disseminated MALT lymphoma. He presented with non-productive cough, initial chest radiograph showed a nodule in the right lower lobe. The diagnosis of stage IV MALT lymphoma was made by CT scan, video-assisted thoracoscopic excisional biopy, gastrofiberscopic biopsy and bone marrow biopsy. The lymphoma involved the lung, stomach and bone marrow at the time of diagnosis. Because he refused chemotherapy, he discharged after Helicobacter pylori eradication without chemotherapy. Regular follow-up examination did not show any evidence of disease progression over 22 months.

Clinical Manifestation and Treatment Results of the Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue Arising in the Head and Neck Region (두경부의 점막연관 림프조직에서 발생한 림프절외 변연부 B세포 림프종의 임상 양상 및 치료 결과에 대한 고찰)

  • Rah, Yoon-Chan;Han, Kyu-Hee;An, Soo-Youn;Kwon, Tack-Kyun;Sung, Myung-Whun;Kim, Kwang-Hyun;Hah, J.-Hun
    • Korean Journal of Head & Neck Oncology
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    • v.25 no.2
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    • pp.128-131
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    • 2009
  • Objectives : Mucosa-associated lymphoid tissue(MALT) lymphoma of the head and neck region is relatively rare, but it has variable clinical and biological characteristics. Although there were few studies on this topic, there is still controversy regarding the best treatment. The authors retrospectively investigated the clinical courses and treatment results in 10 patients presenting with MALT-lymphoma in head and neck region except ocular adnexa. Material and Methods : Ten patients with a histologically verified diagnosis of the extranodal marginal zone B cell lymphoma arising in thyroid glands(3), larynx(3), oral cavity(2), oropharynx(1), salivary glands(1) were analyzed. Results : Four patients were allocated to stage IE and another six patients to stage IIE according to the Ann Arbor staging system. Treatment consisted of local therapy(surgical resection and/or radiotherapy) in four patients and systemic chemotherapy with/without local therapy in six patients. Complete remission and partial remission were achieved in seven patients(70%) and two patients(20%), respectively. No recurrence or mortality was observed with a mean follow-up of 40.5 months. Conclusion : Patients with MALT-lymphomas of the head and neck region were potentially treated by local modality in localized disease state. However systemic chemotherapy was also effective even in localized disease state and was well tolerated by patients. And strict staging and close long-term monitoring were recommended considering its indolent progression.

Surgical Experience with Pull-through Operation in Hirschsprung's Disease of the Descending Colon (하행결장에 발생한 Hirschsprung씨 병의 Pull-through수술 경험)

  • Hong, Jeong
    • Advances in pediatric surgery
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    • v.10 no.1
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    • pp.60-62
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    • 2004
  • Leveling colostomy with a frozen-section biopsy in a Hirschsprung's disease is an important factor for a successful procedure. Two neonatal cases of Hirschsprung's disease in the descending colon are reported. In both cases, loop ileostomy was established because of the unavailability of frozen-section biopsy on an emergency basis. At the time of definitive procedure of the first case, transition zone at the splenic flexure was noted and was compatible with the frozen section biopsy. In the second case, an unexpected longer resection at a higher level than transition zone was required because of the poor vascularity after dissection. In conclusion, a leveling colostomy should be selected as a choice in long-segment Hirschsprung's disease. Confirming preservation of the marginal artery of Drummond is particularly important in case of Hirschsprung's disease in the descending colon.

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A Network partition Technique Using Marginal Cost Sensitivity Under Transmission Congestion (송전 혼잡하에서 한계비용 민감도를 이용한 계통분활)

  • Kim, Sung-Pil;Mang, Keun-Ho;Jeong, Hae-Seong;Park, Jong-Keun
    • Proceedings of the KIEE Conference
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    • 2002.11b
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    • pp.111-113
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    • 2002
  • 본 논문에서는 경쟁적 전력시장에서 송전 계약에 관한 비용을 모선에서 한계비용 만감도를 이용해서 분할하는 방법을 제시하였다. 구조개편된 전력사장에서는 단순하면서도 분명한 전력 요금 시스템이 요구된다. Zonal pricing은 이런 면에서 좋은 pricing 시스템이 요구된다. 하지만, zone을 효과적으로 나누는 것은 상당히 어렵다. 기존의 방법에서는 오직 부하만을 고려하여 분류를 하였지만, 에너지 시장에서의 전력의 매매행위를 고려할 때, 시스템 내부의 모든 사업자에 대한 고려가 필요하다. 그래서, 본 논문에서는 한계비용 민감도를 이용해서 모든 에너지 시장 참여자를 고려하여, 네트워크를 분할하였다. 모든 노드에서의 민감도의 패턴이 분석되었고 동일한 패턴을 가진 노드들을 같은 zone으로 분류하였다. 6-모선 전력시스템을 이용해서 제안한 방법을 설명하였다.

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Creep and creep crack growth behaviors for base, weld, and heat affected zone in a grade 91 weldment

  • Kim, Woo-Gon;Sah, Injin;Kim, Seon-Jin;Lee, Hyeong-Yeon;Kim, Eung-Seon
    • Nuclear Engineering and Technology
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    • v.53 no.2
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    • pp.572-582
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    • 2021
  • This study investigated the creep and creep crack growth (CCG) behavior of the base metal (BM), weld metal (WM), and heat affected zone (HAZ) in a Gr. 91 weldment, which was made by a shield metal arc weld process. A series of tensile, creep, and CCG tests were performed for the BM, WM, and HAZ at 550 ℃. Creep behavior of the BM, WM, and HAZ was analyzed in terms of various creep laws; Norton's power-law, Monkman-Grant relation and damage tolerance factor (λ), and their constants were determined. In addition, each CCGR law for the BM, WM, and HAZ was proposed and compared in terms of a C*-fracture parameter. The WM and HAZ revealed faster creep rate, lower rupture ductility, and faster CCGRs than the BM, but they showed a similar behavior in the creep and CCG. The CCGRs obtained in the present study exhibited a marginal difference when compared with those of RCC-MRx of currently elevated design code in France. A creep crack path in the HAZ plane progressed towards a weak fine-grained HAZ adjacent to the BM.

Benefit of volumetric-modulated arc therapy over three-dimensional conformal radiotherapy for stage I-II extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue in the stomach: a dosimetric comparison

  • Chung, Joo-Hyun;Na, Kyoungsu;Kim, Il Han
    • Radiation Oncology Journal
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    • v.36 no.4
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    • pp.332-340
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    • 2018
  • Purpose: To retrospectively analyze dosimetric parameters of volumetric-modulated arc therapy (VMAT) and three-dimensional conformal radiotherapy (3D-CRT) delivered to extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue in the stomach (gastric MALT lymphoma) to find out advantages of VMAT and conditions for definite benefits of VMAT. Materials and Methods: Fifty patients with stage I-II gastric MALT lymphoma received VMAT (n = 14) or 3D-CRT (n = 36) between December 2005 and April 2018. Twenty-seven patients were categorized according to whether the planning target volume (PTV) overlaps kidney(s). Dosimetric parameters were analyzed by dose-volume histogram. Results: Radiation dose to the liver was definitely lower with VMAT in terms of mean dose (p = 0.026) and V15 (p = 0.008). The V15 of the left kidney was lower with VMAT (p = 0.065). For those with PTV overlapping kidney(s), the left kidney V15 was significantly lower with VMAT. Furthermore, the closer the distance between the PTV and kidneys, the less the left kidney V15 with VMAT (p = 0.037). Delineation of kidney(s) by integrating all respiratory phases had no additional benefit. Conclusions: VMAT significantly increased monitor units, reduced treatment time and radiation dose to the liver and kidneys. The benefit of VMAT was definite in reducing the left kidney V15, especially in geometrically challenging conditions of overlap or close separation between PTV and kidney(s).