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검색결과 562건 처리시간 0.029초

Pantoea agglomeranso에 의한 Hydroxyapatite의 인산화

  • 임원봉;정일;이기영;김도만;김시욱;박돈희
    • 한국생물공학회:학술대회논문집
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    • 한국생물공학회 2001년도 추계학술발표대회
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    • pp.414-417
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    • 2001
  • 불용성 인산염인 hydroxyapatite를 분해하여 인산을 생성하는 미생물인 P. agglomerans의 성장에 따른 인산의 생성량을 여러 산으로 처리하였을 때와 비교하여 보았다. P. agglomerans 의 성장에 있어서 필요한 인산의 양은 300mg/L에서 361mg/L 정도의 인산을 소모하였다. 또한 여러 유기 및 무기산으로 4% 의 hydroxyapatite를 처리하였을 때에 0.01N 의 시트르산과 옥살산으로 처리하였을 때 만이 인산의 생성량은 P. agglomerans 에서 보다 높은 각각 702와 537mg/L 이었고 배양후 48 시간이 지났을 때 P. agglomerans 의 유리인산의 최대가용화량은 465mg/L이었다.

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다중 시계열 모델을 이용한 단기 부하 무효전력 예측 (Short-term Reactive Power Load Forecasting Using Multiple Time-Series Model)

  • 이효상;조종만;박우현;김진오
    • 조명전기설비학회논문지
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    • 제18권5호
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    • pp.105-111
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    • 2004
  • 본 논문에서는 실제 전력 수요 데이터를 이용하여 유효전력에 단기 부하 예측함에 있어 무효전력이 중요한 역할을 하는 것을 회귀 분석 검정 통계량으로 증명한다. 무효전력의 공급과 수요는 계통의 전압과 아주 밀접한 관계를 가지고 있으므로 계통전압을 관리하고 계통의 신뢰도를 높이기 위해서는 예측된 무효전력 수요에 따라 무효전력 공급계획을 별도로 수립하여 운영해야 한다. 따라서 본 논문에서는 다중 시계열 모델을 이용한 시전 예측방법을 이용하여 설명변수로 유효전력을 사용하여 부하의 무효전력을 예측 하였다.

In vitro Drug Release Characteristics of Methotrexate-Human Serum Albumin and 5-Fluorouracil-Acetic Acid Human Serum Albumin Conjugates

  • Kim, Chong-Kook;Lee, Myung-Gull;Park, Man-Ki-Heejoo;Lee, Hae-Jin;Kang, Hae-Jin
    • Archives of Pharmacal Research
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    • 제12권3호
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    • pp.186-190
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    • 1989
  • The release rates of methotrexate (MTX) from MTX-human serum albumin (HSA) conjugate, and 5-fluorouracil (5-FU) from 5-FU acetic acid (AA)-HSA conjugate were determined after incubation of the conjugates in various conditions. The concentrations of 5-FU released from the conjugate increased monoexponentially, however those of MTX increased biexponentially in all studies. It indicated that there are two distinct types of MTX-HSA linkage, weakly and tightly bound linkages. The release rates of 5-FU were lower than those of MTX in all studies indicating that the bond of 5-FU-AA-HSA conjugate is very stable, which is supported by the higher value of activation energy (39. 9 vs 10. 7 Kcal/mole) using Arrhenius equation. The release rates of MTX and 5 -FU from the conjugates increased with incubation temperatures. Proteolytic enzyme and liver homogenates accelerated significantly the release rates of MTX and 5-FU. Approximately 1.30 and 22.0% of MTX were released after 12 hours of incubation in the absence and presence of protease, respectively. The corresponding values for 5-FU were released after 12 hours of incubation with rat liver homogenates which were diluted 6 times with phosphate buffer of pH 6.0. The MTX-HSA and 5-FU-AA-HSA conjugates were very stable in rat plasma.

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둔상에 의한 요관 손상 1례 (Ureteral Injury Caused By Blunt Trauma: A Case Report)

  • 권오상;문윤수;우승효;한현영;황정주;이장영;이민구
    • Journal of Trauma and Injury
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    • 제25권4호
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    • pp.291-295
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    • 2012
  • Ureteral trauma is rare, accounting for less than 1% of all urologic traumas. However, a missed ureteral injury can result in significant morbidity and mortality. The purpose of this case presentation is to suggest another method for early detection of ureteral injury in blunt traumatic patient. A 47-years-old man was injured in pedestrian traffic accident. He undergone 3-phase abdominal CT initially and had had a short-term follow-up simple. We suspected ureteral injury. Our final diagnosis of a ureteral injury was based on follow-up and antegrade pyeloureterography, he underwent emergency surgery. We detected the ureteral injury early and took a definitive action within 24 hours. In blunt trauma, if abnormal fluid collection in the perirenal retroperitoneal space is detect, the presence of a ureteral injury should be suspected, so a short-term simple X-ray or abdominal CT, within a few hours after initial abdominal CT, may be useful.

지주막하강에 투여한 Morphine으로 인한 소양감에 대한 임상적 고찰 (A Clinical Study on Pruritus Due to Intrathecal Morphine)

  • 정찬종;백승완;김인세;정규섭
    • The Korean Journal of Pain
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    • 제1권1호
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    • pp.91-97
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    • 1988
  • Herein is a review of eigthy six surgical cases from March to August, 1986 which recieved tetracaine hydrochloride spinal anesthesia. In an attempt to relieve postoperative pain, 0.5 mg morphine sulfate was administrated into the lumbar subarachnoid space. Pruritus, a side effect of intraspinal morphine, was explored in detail. The results were as follows : 1) The incidence of pruritus was 67.4%, 65.5% in man and 71.0% in woman. 2) The time of onset of pruritus was between 30 and 120 minutes with an average of 79.1 minutes. 3) Pruritus primary occurred on the face(87.9%), especially on the nasal, perinasal and periocular areas. Other sites included the scalp, neck, chest, abdomen, shoulder, hip, thigh, flank, and whole body. 4) The severity of pruritus was classified as mild and moderate, but 4 cases(6.9%) were regarded as severe and were treated with naloxone. 5) The duration of pruritus was from 15 minutes to 19 hours with an average of 4.7 hours. 6) There was no significant difference in the prevention of pruritus between the group recieving diphenhydramine and the one which received normal saline.

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기초 매스콘크리트의 수화열 저감을 위한 초지연제 응결시간차 공법의 현장 적용 (Construction Considering the Difference of Setting Time of Super Retarding Agent for Reduction of Hydration Heat of Footing Mass Concrete)

  • 황인성;배정렬;윤석명;김기철;오선교;한천구
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2003년도 학술.기술논문발표회
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    • pp.95-98
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    • 2003
  • This paper presents the results of field experiment to apply the difference of setting tine method using super retarding agent for reducing hydration heat of mass concrete of foundation. According to the results, as the properties of fresh concrete, base concrete satisfies aimed slump and air content, and there is no difference of slump and air content with mixture of super retarding agent. The mixing ratio of super retarding agent is determined for setting time to be retarded by 12 hours in comparison with base concrete, but because the temperature of the air and concrete is low, the difference of setting time is retarded to 24 hours. In man concrete of foundation to which the difference of setting time method is applied, crack by hydration heat is not seen because the lower concrete of super retarding agent generates heat after generation of hydration heat of the upper concrete.

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하악골 부분절제술을 받은 환자에서 발생한 기도 관리 실패 (Failed Airway Management in a Patient with Wound Hematoma After Partial Mandibulectomy and Reconstruction with Free Flap)

  • 김석곤;송재격;강봉진;김철환;최규운
    • 대한치과마취과학회지
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    • 제13권3호
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    • pp.127-131
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    • 2013
  • We experienced failed airway management in a patient who had partial mandibulectomy and reconstruction with free-flap. 40 year-old man (height: 164 cm, body weight: 59 kg) with malignant melanoma on #38 tooth area of mandibular body was scheduled for partial mandibulectomy and reconstruction with free flap. Approximately fifteen-hours after surgery, the patient was extubated without complication. Seven hours after extubation, we experienced respiratory failure andfailed airway managementdue to airway edema and neck. We failed orotracheal intubation with direct laryngoscopy andlaryngeal mask airway, thus we tried tracheostomy but the patient was hypoxic state for more than 30 minutes. The patient had got hypoxic brain damage in whole cerebral cortex and basal ganglia. We should have the policy of airway management of the patients who have massive oro-maxillo-facial surgery and all medical personnel who treat these patients should be educated the policy and airway management methods.

기포제 종류에 따른 경량기포콘크리트의 단열특성에 관한 실험적 연구 (An Experimental Study on the Insulation Property of Light-Weight Foamed Concrete according to Foaming Agent Type)

  • 최훈국;선정수;이정구;최덕진;정지용;김진만
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2007년도 추계 학술논문 발표대회
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    • pp.27-30
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    • 2007
  • Recently, use of light-weight panel is increasing in building. Styrofoam sandwich panel is inexpensive and it is excellent in insulation ability and constructability. But styrofoam of panel inside is low ignition point. Consequently, when panel is fired, it is occur in poisonous gas. On the other hand, light-weight foamed concrete is excellent in insulation ability, fire resistance due to inner pore. Properties of light-weight concrete is influenced by foaming agent type. Accordingly, this study investigate in insulation property of according to foaming agent type in order to using light-weight foamed concrete instead of styrofoam. As a results, Non-heating zone temperature of light-weight foamed concrete of using AP, FP are lower than light-weight foamed concrete of using AES. Light-weight foamed concrete of using AES, FP are satisfied with fire performance of two hours at foam ratio 50, 100. Light-weight foamed concrete of using AP is satisfied with fire performance of two hours at AP ratio 0.1, 0.15. Insulation property is better closed pore by made AP, FP than open pore by made AES.

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溫度順應이 흰쥐의 血淸알칼리 및 酸性 Phosphatase 活性에 미치는 影響 (Effect of Temperature Acclimation on Activities of Serum Alkaline and Acid Phosphatases of the Rat)

  • Kim, Duk-Man
    • 한국동물학회지
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    • 제18권4호
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    • pp.173-180
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    • 1975
  • Sprague-Dawley 系인 成熟한 雄性흰쥐를 對照群과 實驗群으로 나누어 對照群은 $23^\\circ C$에서 保存하였으며 實驗群은 $30^\\circ C 및 33^\\circ C$에서 各各 240時間 및 64時間동안 繼續하여 溫度順應시켰다. 溫熱順應의 各 時間區마다 血淸알칼리性 및 酸性 Phosphatase의 活性을 測定하였다. $30^\\circ C$에서는 上記 酵素活性의 變化相은 $33^\\circ C$에 比하여 一般的으로 顯著하였다. 다시 말하면 $30^\\circ C$에서의 溫熱順應에 있어서 血淸알칼리性 및 酸性 Phosphatase는 對照群에 比하여 一般的으로 높은 活性의 恒定特續性을 나타내었다. 以上의 結果로 미루어 보아 上記 酵素는 $30^\\circ C$의 溫熱順應에 있어서 生化學的으로 直接 또는 間接으로 溫度調節에 關與하고 있는 것으로 思料된다.

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Ulnar artery access for intracranial mechanical thrombectomy procedure: A salvage option after failed trans-femoral and trans-radial access

  • Muhammad U Manzoor;Abdullah A Alrashed;Ibrahim A Almulhim;Sultan Alqahtani;Fahmi Al Senani
    • Journal of Cerebrovascular and Endovascular Neurosurgery
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    • 제25권4호
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    • pp.429-433
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    • 2023
  • 84 years old gentle man with past medical history of hypertension and diabetes presented with sudden onset right sided weakness and aphasia for two hours. Initial neurological assessment revealed National Institute of Health Stroke Scale (NIHSS) 17. Computed tomography (CT) scan demonstrated minimal early ischemic changes along left insular cortex with occlusion of left middle cerebral artery (MCA). Based on clinical and imaging findings, decision was made to perform mechanical thrombectomy procedure. Initially, right common femoral artery approach was utilized. However, due to unfavorable type-III bovine arch, left internal carotid artery could not be engaged via this approach. Subsequently, access was switched to right radial artery. Angiogram revealed small caliber radial artery, with larger caliber ulnar artery. Attempt was made to advance the guide catheter through the radial artery, however significant vasospasm was encountered. Subsequently, ulnar artery was accessed and successful thrombolysis in cerebral infarction (TICI) III left MCA reperfusion was achieved with a single pass of mechanical thrombectomy via this approach. Post procedure neurological examination demonstrated significant clinical improvement. Doppler ultrasound 48 hours after the procedure demonstrated patent flow in radial and ulnar arteries with no evidence of dissection.