• Title/Summary/Keyword: Mammals

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Recent Research on Production of Cloned Animals by Nuclear Transplantation (핵이식에 의한 복제동물 생산의 최근 연구 성과)

  • 박충생
    • Journal of Embryo Transfer
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    • v.8 no.1
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    • pp.37-44
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    • 1993
  • Nuclear transplantation techinque has been found to be the most potential and efficient method for producing a large number of genetically identical animals from a single embryo. The technical development of nuclear transplantation in mammals and its application to the production of cloned animals were reviewed. For the efficient and successful production of cloned embryos by nuclear transplantation, selection and micromanipulation of recipient eggs or embryos as capacious recipient cytoplasm, and benefitial preparation of multiple totipotent embryonic cells as donor nuclei, and also fusion technique are very critical. Recent works approaching to these critical points were introduced and discussed.

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THE EFFECTS OF POLYCHLORINATED BIPHENYLS (PCBs) ON THE AhR AND ER ACTIVITY

  • Joung, Ki-Eun;Min, Kyung-Nan;Yoon, Hyun-Jung;Y.Y Sheen
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.05a
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    • pp.130-130
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    • 2002
  • Polychlorinated biphenyls (PCBs) are persistent environmental contaminants that elicit a broad spectrum of toxic effects in mammals and other vertebrate species. Because of their lipophilicity, chemical stability and resistance to biodegradation, PCBs tend to accumulate in the human body via food chain and environmental matrices including human adipose tissues, blood and milk.(omitted)

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Biology and Potential Use of Chicken Bone Marrow-derived Cells

  • Ko, Dongwoo;Lim, Jeong Mook
    • Journal of Embryo Transfer
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    • v.33 no.1
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    • pp.31-40
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    • 2018
  • Developmental aspects of chicken embryos showed dramatic difference compared with those of mammals and consequently, such difference in various developmental events leads to different feasibility in both clinical and industrial application. We have concentrated on the studies for using of chicken bone marrow cells and currently we found number of unique cellular properties. Through this article, we reviewed characteristics and cell signaling of osteogenic cells during endochondral ossification in chicken long bone.

Polychlorinated Biphenyls (PCBs) in the Bio-geochemistry of Oceans

  • Kannan, Narayanan
    • Journal of Marine Bioscience and Biotechnology
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    • v.2 no.4
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    • pp.201-208
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    • 2007
  • Polychlorinated biphenyls (PCBs) are anthropogenic contaminants found globally in water, ice, soil, air and sediment. Modern analytical techniques allow us to determine these chemicals in environmental matrices at parts per trillion levels or lower. Environmental forensic on PCBs opens up new avenues of investigation such as transport and fate of water masses in oceans, sedimentation, onset of primary production, migration of marine mammals, their population distribution and pharmacokinetics of drugs inside organisms. By virtue of persistence, bioaccumulation, bioconcentration and structure-activity relationship PCBs emerge as unconventional chemical tracers of new sort.

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Role of Aquaporins in Body Fluid Homeostasis

  • Jung, Jin-Sup;Kim, Yong-Keun;Lee, Sang-Ho
    • Proceedings of the Korean Biophysical Society Conference
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    • 1999.06a
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    • pp.28-28
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    • 1999
  • The movement of water across cell plasma membranes occurs in all cell types but is particularly rapid in erythrocytes, renal tubular cells. In principle, osmotic/oncotic gradients and hydrostatic pressure difference can drive water across a cell layer by transcellular or paracellular pathways. The aquaporin family of molecular water channels, which now number 10 in mammals and many more in plants and lower organism, are likely to provide a molecular pathway for water transport in some cell membranes.(omitted)

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EROGOTHIONEINE RESCUES PCl2 CELLS FROM BETA-AMYLOID-INDUCED APOPTOTIC DEATH

  • Jang, Jung-Hee;Surh, Young-Joon
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.141.2-142
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    • 2003
  • beta-Amyloid (A$\beta$) peptide is the major component of senile plaques and considered to have a causal role in the development and progression of Alzheimer's disease. There has been compelling evidence supporting that $A\beta$-induced cytotoxicity is mediated through oxidative and/or nitrosative stress. Recently, considerable attention has been focused on dietary manipulation of oxidative and/or nitrosative damage. L-Egrothioneine (EGT) is a low-molecular weight naturally occurring thiol compound of dietary origin which exists in milimolar concentrations in the brain, liver, kindney, erythrocytes, ocular tissues and in seminal fluids of mammals. (omitted)

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Role of Acyl-CoA Synthetase 4, an Arachidonate-Preferring Enzyme Expressed in Steroidogenic Tissues

  • Kang, M.J.
    • Korean Journal of Animal Reproduction
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    • v.24 no.4
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    • pp.339-341
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    • 2000
  • In mammals, fatty acid utilization is initiated by activation of fatty acid, catalyzed by acyl-CoA synthetase(ACS, EC6.2.1.3). This enzyme reaction is essential in fatty acid metabolism, since mammalian fatty acid synthetase contains a specific thioesterase to produce fatty acid as th $\varepsilon$ final reaction product. Acyl-CoA, the product of ACS, is utilized in various metabolic pathways including membrane biogenesis, energy production and fat deposition. (omitted)

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