THE EFFECTS OF POLYCHLORINATED BIPHENYLS (PCBs) ON THE AhR AND ER ACTIVITY

  • Joung, Ki-Eun (College of Pharmacy, Ewha Womans University) ;
  • Min, Kyung-Nan (College of Pharmacy, Ewha Womans University) ;
  • Yoon, Hyun-Jung (College of Medicine, HanYang University) ;
  • Y.Y Sheen (College of Pharmacy, Ewha Womans University)
  • Published : 2002.05.01

Abstract

Polychlorinated biphenyls (PCBs) are persistent environmental contaminants that elicit a broad spectrum of toxic effects in mammals and other vertebrate species. Because of their lipophilicity, chemical stability and resistance to biodegradation, PCBs tend to accumulate in the human body via food chain and environmental matrices including human adipose tissues, blood and milk.(omitted)

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