• Journal of the Society of Cosmetic Scientists of Korea
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• v.30 no.4 s.48
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• pp.445-448
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• 2004

Aging is divided into intrinsic aging and photo-aging. Intrinsic aging is naturally occurred as the time passed and photo-aging is induced by the UV radiation of skin. The main reason of aging is the free radicals and the degeneration of the cellular materials by free radicals. In this paper, we checked the anti-aging effects of Mallotus japonicus bark extracts. It has the ability to scavenge free radicals and the SOD like activity. Also, it reduced the cell damage by hydrogen peroxide treatment. Mallotus japonicus bark extracts showed the excellent activity on inhibiting the UV induced cell damage and DNA damage. In conclusion, Mallotus japonicus bark extracts can be used as active ingredients for anti-aging cosmetics.

• Korean Journal of Food Science and Technology
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• v.33 no.2
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• pp.271-277
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• 2001

Ethanol extracts from Mallotus japonicus Muell exhibited strong antimicrobial activities by paper disc diffusion method on the five strains of Listeria monocytogenes(ATCC 19111, ATCC 19112, ATCC 19113, ATCC 19114 and ATCC 15313). Ethanol extract from Mallotus japonicus Muell was subsequently fractionated by n-hexane, chloroform, ethyl acetate and water. n-Hexane fraction of Mallotus japonicus Muell showed strong growth inhibition at concentrations as low as 20 ppm level in broth culture medium on the five strains of L. monocytogenes for 72 hr at $30^{\circ}C$. Single substance(M34-4-4) was isolated from n-hexane fraction of Mallotus japonicus Muell. M34-4-4 showed a bactericidal activity against L. monocytogenes at a concentration of 50 ppm level. The purified M34-4-4 was identified as linolenic acid by $^1H-NMR,\;DEPT-135\;and\;^{13}C-NMR$.

• Korean Journal of Environment and Ecology
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• v.15 no.3
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• pp.224-229
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• 2001

The vascular plants in Chilsan islet were summarized as 84 taxi; 37 families, 74 genus, 71 species, 13 varieties. Evidence from the species distribution such as Cudrania tricuspidata and Mallotus japonicus, this islet belongs to the Southern province in phytogeographical point of view. The dominant species in the studied areas are in the follows; Both Carex boottiana and Artemisia carpillaris are in the Islet I, Carex boottiana for the Island II, Both Carex boottiuna and Mallotus japonicus fur the Island III. Clerodendron trichotomum for the Island IV. Both Miscanthus sinensis and Imperate cylindrie var. koenigii for the Island Ⅵ, respectively.

• Korean Journal of Pharmacognosy
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• v.51 no.2
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• pp.115-121
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• 2020

Caenorhabditis elegans model system was used to investigate the antioxidant activity of methanol extract of Mallotus japonicus twigs. The ethyl acetate soluble fraction of the M. japonicus methanol extract showed the best DPPH radical scavenging activity. The ethyl acetate fraction was measured for the activity of superoxide dismutase (SOD), catalase, and oxidative stress tolerance by using C. elegans along with reactive oxygen species (ROS) level. In addition, to confirm that the regulation of the stress response gene is responsible for the increased stress tolerance of C. elegans treated by the ethyl acetate fraction, SOD-3 expression was measured using a transgenic strain. As a result, the ethyl acetate fraction increased SOD and catalase activity, and decreased ROS accumulation in a dose-dependent manner. In addition, the ethyl acetate fraction-treated CF1553 worm showed higher SOD-3::GFP intensity than the control worm.

• Korean journal of applied entomology
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• v.52 no.2
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• pp.93-100
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• 2013

In this study, the distribution of Cantao ocellatus in Korea occurred at Jindo, Tongyoung, Gwangju and Taean including Jejudo in 2012 and was coincidentally in accordance with the distribution of Mallotus japonicus as a host plant. The adult emerges in M. japonicus occur from late June to early July and can be observed until the end of October. The investigation of the female and male was measured, developmental characteristics, host plant and oviposition preference under the conditions of temperature $25^{\circ}C({\pm}2)$, humidity 65%(${\pm}2$), day length 16L:8D, by indoor breeding. For females and males respectively, average body lengths were 26.20 mm and 23.88 mm, body widths 11.35 mm and 10.57 mm, head widths 3.84 mm and 3.64 mm, probosics lengths 7.90 mm and 7.27 mm, antennal lengths 9.87 mm and 9.69 mm, anterior leg lengths 12.50 mm and 12.27 mm, intermediate leg lengths 14.61 mm and 13.12 mm, posterior leg lengths 16.90 mm and 16.53 mm, and fresh weights 0.46 g and 0.31 g. It was seen that two kinds of C. ocellatus had prickles at the end of the pronotum which had developed in the fifth instars. The female is distinguished from the male by the reproductive organ and the spotted pattern on the abdominal segment. The preference of drinks was fruit, leafstalk, midrib, and branch in Mallotus japonicus (Thunb.) Muell. Arg., Mallotus japonicus 'Variegatus', Ricinus communis L., Lonicera japonicus var. repens (Siebold) Rehder, Citrus sinensis (L.) Osbeck and Zelkova serrata (Thunb.) Makino.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.11 no.6
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• pp.61-72
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• 2008

This study was carried out to analyze vegetation and soil characteristic of Osmanthus insularis community, Geomundo. The Osmanthus insularis community was classified into three subcommunities: Mallotus japonicus subcommunity, Ficus erecta subcommunity, Raphiolepis umbellata subcommunity. The importance value of Camellia japonica, Osmanthus insularis, Ligustrum japonicum, Litsea japonica Mallotus japonicus, Pinus thunbergii and Ficus erecta in Osmanthus insularis community were 76.11%, 75.91%, 37.24%, 21.99%, 18.35%, 17.64% and 11.91%, respectively. According to the DBH analysis. Osmanthus insularis showed formality distribution style among the entire community. Their dominance is expected to continue. But the young plant individual were low density, importance value reduced. In the study sites, soil organic matter, nitrogen, available phosphorous and soil pH were ranged from 19.11~24.62%, 0.73~1.18%, 11.61~27.98mg/kg and 6.11~6.37, respectively. According to the result of survey Osmanthus insularis individual, the female plants individual were 57.90%, the male plants individual were 42.10%.

• Korean Journal of Pharmacognosy
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• v.31 no.3
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• pp.351-356
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• 2000

The hepatoprotective effects of bergenin and its derivative, acetylbergenin, were evaluated against D-galactosamine-induced liver damage in rats. Bergenin is a C-glucoside of 4-O-methyl gallic acid that has been isolated from the cortex of Mallotus japonicus (Euphorbiaceae). Acetylbergenin was synthesized from acetylation of bergenin to increase lipophilic and physiological activities. Bergenin (50, 100 and 200 mg/kg) and acetylbergenin (25, 50 and 100 mg/kg) were administered orally once daily for successive 5 days after the injection of galactosamine (400 mg/kg, i.p.), respectively. The substantially elevated serum enzyme activities of alanine/aspartate aminotransferase, sorbitol dehydrogenase and ${\gamma}-glutamyltransferase$ due to galactosamine treatment were dose-dependently restored towards normalization by post-treatment with bergenin and acetylbergenin. Bergenin and acetylbergenin also significantly prevented the elevation of hepatic malondialdehyde formation and depletion of reduced glutathione content induced by galactosamine in a dose-dependent manner. In addition, the decreased activities of glutathione S-transferase and glutathione reductase were restored towards normalization. These results suggest that effects of bergenin and acetylbergenin may be related to complex mechanisms that involve prevention of lipid peroxidation and preservation of hepatic glutathione. The results of this study clearly indicate that bergenin and acetylbergenin have potent hepatotherapeutic action against galactosamine-induced hepatotoxicity in rats, and lipophilic acetylbergenin is more active in the antihepatotoxic effects against galactosamine than much less lipophilic bergenin.

• Biomolecules & Therapeutics
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• v.8 no.4
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• pp.293-298
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• 2000

Bergenin is a C-glucoside of 4-O-methyl gallic acid that has been isolated from the cortex of Mallotus japonicus (Euphorbiaceae). Acetylbergenin was synthesized by acetylation from bergenin to increase lipophilic and physiological activities. The therapeutic effects of bergenin and acetylbergenin were evaluated against carbon tetrachloride ($CCl_4$)-induced hepatotoxicity in rats. Bergenin and acetylbergenin were administered orally once daily for successive 5 days, after the intraperitoneal injection of a mixture 0.5 m1/kg of $CCl_4$ in olive oil (1:1). The substantially elevated serum enzymatic activities of alanine/aspartate aminotransferase, sorbitol dehydrogenase and ${\gamma}$-glutamyltransferase induced by $CCl_4$ were restored towards normalization by posttreatment with bergenin and acetylbergenin. Bergenin and acetylbergenin also significantly prevented the elevation of hepatic malondialdehyde formation and depletion of glutathione content induced by $CCl_4$ in a dose dependent fashion. In addition, the decreased activities of glutathione S-transferase and glutathione reductase were restored towards normalization. These results suggest that therapeutic effects of bergenin and acetylbergenin may be related complex mechanisms that involve prevention of lipid peroxidation and preservation of hepatic GSH. The results of this study clearly indicate that bergenin and acetylbergenin have potent hepatothrapeutic action against $CCl_4$-induced hepatotoxicity in rats. In addition, acetylbergenin 50 mgHg showed almost the same levels of hepatoprotective activity as those of bergenin 100 mgAg, indicating the fact that lipophilic acetylbergenin is more effective in the hepatoprotective action against $CCl_4$ than bergenin.

• Biomolecules & Therapeutics
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• v.7 no.1
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• pp.35-43
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• 1999

Hepatoprotective effects of Malloti cortex extract (MCE) from Mallotus japonicus against the carbon tetrachloride (CCl$_{4}$) and galactosamine (GalN) were investigated. Whereas serum aspartate aminotransferase and alanine aminotransferase levels were markedly elevated after CCl$_{4}$ and GalN administration, pretreatment and posttreatment with MCE before and after the injection of CCl$_{4}$ and GalN resulted in decreases in elevated serum aminotransferase activities. Whereas CCl$_{4}$ and GalN treatment caused 3~7 fold increases in sorbitol dehydrogenase and ${\gamma}$-glutamyltransferase activities, pretreatment and posttreatment with MCE resulted in the blocking of CCl$_{4}$ and GalN-induced liver toxicity. The hepatoprotective effect of MCE was in part due to MCE-induced elevation of hepatic glutathione levels. Pretreatment and posttreatment with MCE also reduced increased lipid peroxidation induced by CCl$_{4}$ and GalN. These results suggest that MCE may be useful for the prevention and therapy of hepatotoxic pathogenesis. It is presumed that protective and therapeutic effects of MCE due to be inducible glutathione S-transferase and glutathione reductase activities, involving in glutathione-medicated detoxication and maintainment of glutathione content, respectively.

• Journal of Korean Society of Forest Science
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• v.88 no.3
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• pp.374-378
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• 1999

In present study, perforated ray cells were recorded for the first time in the species of Berberis amurensis and Berberis poiretii (Berberidaceae) and Mallotus japonicus and Sapium japonicum (Euphorbiaceae) that grow in Korea. These ray cells had simply perforations in the above species which had vessel elements with simple perforations, In Korean Berberidaceae and Euphorbiaceae, thus, the perforation types of perforated ray cells appeared to be identical with the types of perforation plates in the vessel elements is the same wood.