• Title/Summary/Keyword: Major Function

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Double-stranded RNA Induces Inflammatory Gene Expression in Schwann Cells: Implication in the Wallerian Degeneration

  • Lee, Hyun-Kyoung;Park, Chan-Hee;Choi, Se-Young;Oh, Seog-Bae;Park, Kyung-Pyo;Kim, Joong-Soo;Lee, Sung-Joong
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.5
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    • pp.253-257
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    • 2004
  • Schwann cells play an important role in peripheral nerve regeneration. Upon neuronal injury, activated Schwann cells clean up the myelin debris by phagocytosis, and promote neuronal survival and axon outgrowth by secreting various neurotrophic factors. However, it is unclear how the nerve injury induces Schwann cell activation. Recently, it was reported that certain cytoplasmic molecules, which are secreted by cells undergoing necrotic cell death, induce immune cell activation via the toll-like receptors (TLRs). This suggests that the TLRs expressed on Schwann cells may recognize nerve damage by binding to the endogenous ligands secreted by the damaged nerve, thereby inducing Schwann cell activation. Accordingly, this study was undertaken to examine the expression and the function of the TLRs on primary Schwann cells and iSC, a rat Schwann cell line. The transcripts of TLR2, 3, 4, and 9 were detected on the primary Schwann cells as well as on iSC. The stimulation of iSC with poly (I : C), a synthetic ligand for the TLR3, induced the expression of $TNF-{\alpha}$ and RANTES. In addition, poly (I : C) stimulation induced the iNOS expression and nitric oxide secretion in iSC. These results suggest that the TLRs may be involved in the inflammatory activation of Schwann cells, which is observed during Wallerian degeneration after a peripheral nerve injury.

Effect of the Electro-acupuncture Stimulation into the Infraspinatus and the Teres Major for the Shoulder Function Improvement and Pain Reduction (극하근과 대원근에 적용한 전침이 견관절 기능 개선 및 통증 경감에 미치는 영향)

  • Jang, Won-Seok;Bae, Sung-Soo
    • The Journal of Korean Physical Therapy
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    • v.19 no.6
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    • pp.43-47
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    • 2007
  • Purpose: This study examined the effect of electro-acupuncture stimulation of the infraspinatus and teres major on the shoulder function reduction. The subjects consisted of 20 female patients with a shoulder dysfunction. Methods: The 20 female patients with shoulder dysfunction participated voluntary in this research. 10 minute electro-acupuncture stimulation (frequency: 5Hz, Intensity: below the pain threshold) with Infra-red therapy, 3 times per week given to the patients' Trigger point of the infraspinatus and teres major. The Visual Analog Scale (VAS), Apley's Scratch Test and Global Perceived Effect Scale (GPES) were examined before alter six applications. Results: There was a significant decrease in the VAS (p<0.05) and Apley's Scratch Test (p<0.05). In addition, there was statistically significant increase in the Global Perceived Effect Scale (p<0.05). Therefore, the infraspinatus and teres major is a very important muscle for the shoulder function. Conclusion: This data will be used to develop a treatment method for patients with a shoulder dysfunction. These results suggest that the electro-acupuncture stimulation into the infraspinatus and the teres major Trigger point is an effective intervention for patients with shoulder dysfunction and pain.

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The Effects of Parenting Behaviors on Preschoolers' Executive Function (부·모의 양육행동이 유아의 실행기능에 미치는 영향)

  • Lee, Yoon-Jeong;Kong, Young-Sook;Lim, Ji-Young
    • Journal of Families and Better Life
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    • v.32 no.1
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    • pp.13-26
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    • 2014
  • The purpose of this study was to explore the effects of parenting behaviors on preschoolers' executive function, focusing on methods of measuring executive function. The subjects of this study were 166 preschoolers who were 3 to 5 years of age, and their parents. Data were collected by various performance-based tests and their parents' reports and analyzed by descriptive statistics and hierarchical linear regression analysis using the SPSS 19.0 program. The major results were as follows: First, maternal autonomous and paternal affective parenting behaviors significantly affected preschoolers' performance-based executive function. Second, maternal affective parenting behaviors significantly affected preschoolers' parent-report executive function. The results suggest the importance of positive parenting practices in the development of preschoolers' executive function.

Identification of the Distribution Function of the Preisach Model using Inverse Algorithm

  • Koh, Chang-Seop;Ryu, Jae-Seop
    • KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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    • v.2B no.4
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    • pp.168-173
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    • 2002
  • A new identification algorithm for the Preisach model is presented. The algorithm treats the identification procedure of the Preisach model as an inverse problem where the independent variables are parameters of the distribution function and the objective function is constructed using only the initial magnetization curve or only tile major loop of the hysteresis curve as well as the whole reversal curves. To parameterize the distribution function, the Bezier spline and Gaussian function are used for the coercive and interaction fields axes, respectively. The presented algorithm is applied to the ferrite permanent magnets, and the distribution functions are correctly found from the major loop of the hysteresis curve or the initial magnetization curve.

The Effect of Maternal Cognitive Empathy on Preschooler's Executive Function: Mediating Effects of Preschooler's Caring Behavior and Happiness (어머니의 인지적 공감능력이 유아의 실행기능에 미치는 영향: 유아 배려행동과 행복감의 매개효과)

  • Kong, Youngsook;Lim, Jiyoung;An, Sunjung;Lee, Yoonjeong
    • Human Ecology Research
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    • v.60 no.1
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    • pp.99-113
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    • 2022
  • This study examined the effect of maternal cognitive empathy on children's executive function focusing on mediating effects of preschooler's caring behavior and happiness. The subject of this study was 460 five-year-old preschooler-their mother dyads in Korea. Data were collected by Korean Version of Questionnaire of Cognitive and Affective Empathy(K-QCAE), Caring Behaviors Scale for Young Children, Happiness Scale for Young Children and Behavior Rating Inventory of Executive Function-Preschool Version(BRIEF-P). Data were analyzed using descriptive statistics, independent samples t-test, Pearson correlation analysis, structural equation model and bootstrapping test with SPSS 25.0 and AMOS 23.0 program. The major results were as follows. 1) Maternal cognitive empathy had a positive influence on preschooler's caring behavior. 2) Preschooler's caring behavior had a positive influence on happiness and executive function. 3) Preschooler's happiness had a positive influence on executive function. 4) The effect of maternal cognitive empathy on preschooler's executive function was mediated by preschooler's caring behavior. 5) The effect of maternal cognitive empathy on preschooler's executive function was sequentially mediated by preschooler's caring behavior and happiness. This study revealed that maternal cognitive empathy, preschooler's caring behavior, and happiness have an important role in preschooler's executive function. Most of all, we suggest that maternal cognitive empathy should be improved to promote preschooler's executive function. The findings of this study will contribute to designing intervention programs to improve preschooler's executive function as well as maternal empathy.

The Structural Relationships among Maternal Reflective Function, Preschoolers' Empathy, Executive Functions, and Caring Behaviors (어머니의 반영기능과 유아의 공감능력, 실행기능, 배려행동 간의 구조적 관계)

  • Lee, Yoonjeong;Lim, Jiyoung;An, Sunjung
    • Human Ecology Research
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    • v.60 no.2
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    • pp.177-186
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    • 2022
  • The purpose of this study was to explore the relationships among mothers' reflective function, preschoolers' empathy, executive function, caring behaviors. Subjects for this study were 498 preschoolers and their mothers. Mothers' reflective function was assessed by the Parental Reflective Functioning Questionnaire(PRFQ). Preschoolers' empathy was assessed by the Questionnaire of Cognitive and Affective Empathy(QCAE). Preschoolers' executive function was assessed by the Behavioral Rating Inventory of Executive Functions-Preschool Version(BRIEF-P), and caring behaviors were assessed by the caring behaviors scale(Kim, 2015). Data were analyzed using descriptive statistics, confirmatory factor analysis(CFA), and structural equation model(SEM) with the SPSS 25.0 and AMOS 23.0 program. The major results of this study were as follows. First, mothers' reflective function showed direct effects on preschoolers' empathy, executive function, and caring behaviors. Second, the preschoolers' empathy and executive function showed direct effects on preschoolers' caring behaviors. Third, preschoolers' empathy mediated the effects of mothers' reflective function on preschoolers' caring behaviors. The findings of this study will contribute to designing intervention programs to improve preschoolers' empathy, executive function, and caring behaviors.

Effects of Mentoring Function, Self-Concept, Career Decision-making Self-efficacy, and Major Satisfaction on College Life Adaptation (멘토링 기능, 자아개념, 진로결정 자기효능감, 전공만족도가 대학생활적응에 미치는 영향)

  • Ji-Won Yoon;Mee-Ra Park;Nam-Joo Je
    • Journal of the Korean Society of Industry Convergence
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    • v.27 no.2_2
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    • pp.377-388
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    • 2024
  • The purpose of this study is to prepare basic data to help college students adapt to college life by grasping the effects of mentoring skills, self-concept, career decision-making self-efficacy, and major satisfaction on college life adaptation. To achieve the purpose of the study, data were collected from January 17 to January 27, 2024, targeting college students from one university in C city located in G-do. The survey was conducted online. As a result of the study, the mentoring function of the subjects averaged 4.11 points (out of 5 points), the self-concept was 4.29 points (out of 5 points), the career decision-making self-efficacy was 4.04 points (out of 5 points), the major satisfaction was 4.45 points (out of 5 points), and the college life adaptation was 3.91 points (out of 5 points). The factor that most influenced the subject's adaptation to college life was career decision-making self-efficacy, followed by self-concept, mentoring function, and major-art field. The explanatory power of the model was 70.2%. Specifically, the higher the career decision-making self-efficacy, the higher the self-concept, and the higher the mentoring function, the higher the adaptation to college life. Educational intervention programs (non-curricular programs) are needed to adapt to college life for college students, and subsequent studies need to examine the effects of the developed programs.

Assessment of Ventricular Function Using Gated Blood Pool Scan and Gated Blood Pool SPECT (게이트심장혈액풀 스캔과 게이트심장혈액풀 SPECT를 이용한 심실기능의 평가)

  • Park, Seok-Gun
    • The Korean Journal of Nuclear Medicine
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    • v.39 no.2
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    • pp.100-106
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    • 2005
  • Non-invasive evaluation of cardiac function by nuclear medicine technologies are one of the major contribution of nuclear medicine. Gated cardiac blood pool scan was once a novel and robust technique which enabled evaluation of ventricular function. Concept of EKG gating was one of the major breakthrough in nuclear cardiology. According to the evolution of echocardiographic techniques, and as the evaluation of myocardial perfusion by perfusion SPECT became feasible, number of gated blood pool study dong in nuclear medicine laboratory is declining. And recently, evaluation of ventricular function with gated perfusion SPECT further decreased the use of gated blood pool scan. In this article, assessment of ventricular function using gated blood pool scan is discussed including some insight about the role of gated blood pool SPECT.

An Inquiry on the Building Process of Pedagogical Content Knowledge of Prospective Mathematics Teachers -centered at function concepts- (수학과예비교사들의 교수학적지식 형성 과정 탐구 -함수 개념을 중심으로-)

  • Kang Yun-Soo;Jun Sung-A
    • The Mathematical Education
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    • v.45 no.2 s.113
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    • pp.217-230
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    • 2006
  • The purpose of this study is to inquire the building process of Pedagogical Content Knowledge of prospective mathematics teachers about the function concepts. For this purpose, We performed the following steps; First, we performed the survey relaying to the prospective mathematics teachers' teaching experiences, capabilities of their error evaluation of the students, and viewpoints about the function concepts. Second, we performed the survey on the subject-matter knowledge about the function concepts and the key items of designing teaching plans about the function concepts. And then, we interviewed the participants to check the results of the surveys and to supplement the necessary contents. The collected data was relatively correlative and analyzed in the process. As a result, we found the followings; First, subject-matter knowledge of prospective mathematics teachers about the function concepts is different depending on the grades. Second, prospective mathematics teachers are building more extended function concepts through the major subjects. Third, the major subjects are important to build the Pedagogical Content Knowledge of function concepts. Fourth, teaching experience plays an important role in transforming subject-matter knowledge of function concepts to Pedagogical Content Knowledge of it. Fifth, building the Pedagogical Content Knowledge means transferring the teacher's viewpoint from himself/herself to the learner.

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Memory and Psychiatric Disorders (기억력과 정신질환)

  • Hong, Kyung Sue;Yeon, Byeong Kil
    • Korean Journal of Biological Psychiatry
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    • v.4 no.1
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    • pp.3-11
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    • 1997
  • Disturbances in memory are the most common problem in patients with an organic mental syndrome. Other patients with significant psychiatric disorders also often have difficulty with memory. So it is very important in the clinical practice of psychiatry to understand the biological and neurocognitive mechanisms of memory proessing, and to develop the assessment tools with which memory function can be evaluated reliably and validly. Moreover, memory researches provide an important viewpoint from which we can understand the pathophysiological mechanisms of major neuropsychiatric illnesses. This article focuses on our understanding of memory functions in clinical and neurobiological aspects. The relevant material will be presented in four parts : 1) terminologies needed in defining major stages of various types of memory processing : 2) neurochemical and neuroanatomical basis of memory processing : 3) brief bed-side screening tests and more comprehensive neuropsychological tests for the evaluation of memory function : 4) the characteristics of memory dysfunction in several major psychiatric illnesses.

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