• Journal of the Korea institute for structural maintenance and inspection
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• v.4 no.4
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• pp.211-218
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• 2000

Many bridges are severely damaged by the overloaded heavy vehicle and the trend will become more serious because the traffic volume is continuously increasing. Currently, the vehicles with gross weights over 40 tonf or axle weight over 10 tonf are not allowed on the public road. However, this regulation is not based on a systematic study on the bridge capacity and assumed to be much too conservative depending on the vehicle types and bridge types. In this study, the permit weights of heavy vehicles of diverse axle spacings and axle load distribution are calculated considering the structural characteristics of bridge superstructures. In order to consider the various load effects of heavy weight vehicle crossings, three conditions are considered in the calculation of permit vehicle load. From the results, the permit vehicle weights of the simple girder bridges are calculated.

• Molecules and Cells
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• v.23 no.3
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• pp.272-279
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• 2007

The maintenance of normal blood glucose levels at rest and during exercise is critical. The maintenance of blood glucose homeostasis depends on the coordination and integration of several physiological systems, including the sympathetic nervous system and the endocrine system. During prolonged exercise increased demand for glucose by contracting muscle causes to increase glucose uptake to working skeletal muscle. Increase in glucose uptake by working skeletal muscle during prolonged exercise is due to an increase in the translocation of insulin and contraction sensitive glucose transporter-4 (GLUT4) proteins to the plasma membrane. However, normal blood glucose level can be maintained by the augmentation of glucose production and release through the stimulation of liver glycogen breakdown, and the stimulation of the synthesis of glucose from other substances, and by the mobilization of other fuels that may serve as alternatives. Both feedback and feedforward mechanisms allow glycemia to be controlled during exercise. This review focuses on factors that control blood glucose homeostasis during prolonged exercise.

• Journal of Korean Academy of Nursing
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• v.52 no.6
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• pp.608-623
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• 2022

Purpose: This study aimed to evaluate the effects of a combined biofeedback and brief emotion regulation (C-BABER) program for sexually abused adolescents. Methods: This study employed a non-equivalent control group pretest-posttest design. The participants included 26 sexually abused adolescents from eight Sunflower Centers of South Korea-with 13 in the experimental group and 13 in the control group. The experimental group received four sessions of the individual C-BABER program, each lasting 60 minutes. Results: Compared with the control group, sexually abused adolescents in the experimental group exhibited significant score differences in traumatic symptoms, including depression (Z = - 2.24, p = .025), dissociation (Z = - 2.21, p = .027), anxiety (Z = - 2.02, p = .044), and posttraumatic stress (Z = - 2.01 p = .045); and impulsivity, including positive urgency (Z = - 3.35, p = .001) and negative urgency (Z = - 2.28, p = .023). Additionally, the experimental group exhibited significant score differences in meta-mood, including emotional attention (Z = - 2.45, p = .014), emotional clarity (Z = - 2.30, p = .021), and emotional repair (Z = - 2.28, p = .022); and emotional regulation modes, including emotional suppression (Z = - 2.65, p = .008) and cognitive reappraisal (Z = - 1.98, p = .047). Regarding bio-attention, significant changes were identified in the experimental group for the bio-attention rate and attention maintenance time in the posttest compared to the pretest (p = .001). Conclusion: The C-BABER program for sexually abused adolescents is effective in decreasing traumatic symptoms and impulsivity, and in improving meta-mood, emotional regulation mode, and bio-attention. Therefore, we recommend providing sexually abused adolescents the C-BABER program to help them regulate their emotions and effectively adapt to their lives.

• Journal of the Korean housing association
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• v.13 no.5
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• pp.89-99
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• 2002

The multifamily housing has various advantages in construction cost, land-use intensity. KRIHS(1997) recommended the proper scale of th multifamily housing as 800 households in constructability, 1,000 households in facility compactability, 500 households in social aspect. At the early planning stage of project, the size of the multiftmily housing has, until now, been maximizingly considered under the regulation on which has been emphasized at the building volume ratio, land area, etc., except for the expenditure during the maintenance stage. This paper aimed at providing the proper size of multifamily housing in aspect of area and household number with maintenance cost at the early stage of project. For these, it took 곧 average cost function which is made from the 3-rd quardratic form and analyzes the unit increasing rate of the average cost. It surveyed in nationwide focused on the central heating system using diesel and kerosene. The number of samples is 88 and items of management cost is 11. The results are as follows ; first, 3rd-order quadratic function is proper at explaining the cost variation, considering the multicollinearity and statistics. Second, the proper size of multifamily housing is recommended with 83,000 $m^2$ on management area, 820 or over the 2,630 household number in aspect of total management cost.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.2063-2066
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• 2005

This paper presents an approach to detect the dielectric condition of FRP Hot Stick in EHV high voltage cable whereas shutting down the power system is not necessary. The radio frequency generating method is adopted by transmitting radio wave into the Electrodes. This instrument is small, easy to use and also inexpensive. Furthermore, the impurity level of dirt on high voltage insulator (non-ceramic type) will be analyzed by using the methods based on IEEE Std.978-1984 at 105 kV.DC. /305 mm. and OSHA Regulation 1910.269 Part J - live line tools. The frequency at 10-20 MHz is applied to FRP Hot Stick via Electrode1 and from FRP Hot Stick surface to Electrode 2. After that the results will be evaluated by testing in each condition of FRP Hot Stick, such as dry surface, hot surface, foil winding and conductor inserting. Finally, the watt loss will be examined and compared with the loss from humidity and Carbon tracking. The important components of this system are radio frequency generating unit, frequency stabilizing unit, frequency amplifier, FRP Hot Stick frequency counter, processing unit, and display unit.

• Archives of Pharmacal Research
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• v.29 no.4
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• pp.265-275
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• 2006

In the developing brain, capillaries are differentiated and matured into the blood-brain barrier (BBB), which is composed of cerebral endothelial cells, astrocyte end-feet, and pericytes. Since the BBB regulates the homeostasis of central nervous system (CNS), the maintenance of the BBB is important for CNS function. The disruption of the BBB may result in many brain disorders including brain tumors. However, the molecular mechanism of BBB formation and maintenance is poorly understood. Here, we summarize recent advances in the role of oxygen tension and growth factors on BBB development and maintenance, and in BBB dysfunction related with brain tumors.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.35 no.1
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• pp.63-72
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• 2019

The purpose of this study is that investigated the characteristics of integral planning related factors using the history and culture of Mojiko. It is a small city that has been urbanized after the opening of the port for logistics transportation in the modern period of Japan. As the function of the logistics city, which is the factor of the expansion of the town, declined, Mojiko applied the retro concept to the harbor which has lost its popularity due to the regional characteristics of the city to increase and revitalize local visits. Mojiko has steadily promoted the retro style of landscape and town development over 30 years, focusing on 18 Historical buildings and modern infrastructure. We analyzed characteristics of integrated urban planning include the regulation, landscape institution. Moreover, we suggest the result of the designation process of a core scenery maintenance district and the components of the plan after the designation analysis and provide essential data for revitalizing the field based on the historic city for the cultural establishment and beautiful town in the future. And deliver vital data to reviving the area based on the historical city culture establishment and beautiful town in the future.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.10
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• pp.1398-1406
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• 2016

In general, the seminiferous tubule basement membrane (STBM), comprising laminin, collagen IV, perlecan, and entactin, plays an important role in self-renewal and spermatogenesis of spermatogonial stem cells (SSCs) in the testis. However, among the diverse extracellular matrix (ECM) proteins constituting the STBM, the mechanism by which each regulates SSC fate has yet to be revealed. Accordingly, we investigated the effects of various ECM proteins on the maintenance of the undifferentiated state of SSCs in pigs. First, an extracellular signaling-free culture system was optimized, and alkaline phosphatase (AP) activity and transcriptional regulation of SSC-specific genes were analyzed in porcine SSCs (pSSCs) cultured for 1, 3, and 5 days on non-, laminin- and collagen IV-coated Petri dishes in the optimized culture system. The microenvironment consisting of glial cell-derived neurotrophic factor (GDNF)-supplemented mouse embryonic stem cell culture medium (mESCCM) (GDNF-mESCCM) demonstrated the highest efficiency in the maintenance of AP activity. Moreover, under the established extracellular signaling-free microenvironment, effective maintenance of AP activity and SSC-specific gene expression was detected in pSSCs experiencing laminin-derived signaling. From these results, we believe that laminin can serve as an extracellular niche factor required for the in vitro maintenance of undifferentiated pSSCs in the establishment of the pSSC culture system.

• Molecules and Cells
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• v.40 no.2
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• pp.117-122
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• 2017

Despite the fact that porcine embryonic stem cells (ESCs) are a practical study tool, in vitro long-term maintenance of these cells is difficult in a two-dimensional (2D) microenvironment using cellular niche or extracellular matrix proteins. However, a three-dimensional (3D) microenvironment, similar to that enclosing the inner cell mass of the blastocyst, may improve in vitro maintenance of self-renewal. Accordingly, as a first step toward constructing a 3D microenvironment optimized to maintain porcine ESC self-renewal, we investigated different culture dimensions for porcine ICM-derived cells to enhance the maintenance of self-renewal. Porcine ICM-derived cells were cultured in agarose-based 3D hydrogel with self-renewal-friendly mechanics and in 2D culture plates with or without feeder cells. Subsequently, the effects of the 3D microenvironment on maintenance of self-renewal were identified by analyzing colony formation and morphology, alkaline phosphatase (AP) activity, and transcriptional and translational regulation of self-renewal-related genes. The 3D microenvironment using a 1.5% (w/v) agarose-based 3D hydrogel resulted in significantly more colonies with stereoscopic morphology, significantly improved AP activity, and increased protein expression of self-renewal-related genes compared to those in the 2D microenvironment. These results demonstrate that self-renewal of porcine ICM-derived cells can be maintained more effectively in a 3D microenvironment than in a 2D microenvironment. These results will help develop novel culture systems for ICM-derived cells derived from diverse species, which will contribute to stimulating basic and applicable studies related to ESCs.

• 전기의세계
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• v.14 no.4
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• pp.8-17
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• 1965

Firstly, this study has analyzed the following factors affecting the optimum specifications and design of distributive transformers: 1. Facilities installation cost per unit power output. 2. Facilities operating & maintenance cost per unit power output. 3. Production cost per unit power output. 4. Load factor. 5. Loss factor. Secondly, it has clarified the relations between the following factors and the specifications and design of distributive transformers; 1. No-load loss., 2. Load loss., 3. Voltage regulation., 4. Exciting current. Finally, it has determined the method of the most economic design for the transformers using the above factors and relations, and, for optimum the illustrative purpose, suggested their optimum specifications, way of evaluation, and merits by means of typical example.