• Title/Summary/Keyword: Magnolia obovata Thunb

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Evaluation of Cell Cytotoxicity on the extractives of Magnoliaceae (목련과 수목의 추출성분에 대한 세포독성평가)

  • 김영균;고영남;김용만;양현옥
    • Journal of Korea Foresty Energy
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    • v.20 no.2
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    • pp.1-8
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    • 2001
  • The 90% methanol extracts of eight magnoliaceae plants were collected and tested the cytotoxicity against SK-OV-3 and SiHa cells. Also six pure compounds such as magnonol, honokiol, dihydroxybiphenyl ether, linodenine, anonaine, asimilobine which were previously isolated from Magnolia obovata Thunb. were evaluated the cytotoxicities and their mechanism study using the Lactate dehydrogenase assay(LDH) and FACScan analysis system. Of the tested six compounds, magnonol, honokiol, dihydroxybiphenyl ether showed high cytotoxicities against human cancer cell lines, SK-OV-3 and SiHa cells. In addition, one of the plausible mechanisms of their antitumor activities suggested that they could induce the early stage of apoptosis. For the quantitative analysis, the methanol extractives were fractionated with chloroform, ethylacetate, $H_2O$ and then the ethylacetate fraction was chromatographed on silica gel using n-Hexane ; Acetone(4:1, v/v) as eluent. This fraction was subjected for the quantitative analysis in the HPLC system. The result suggested that the methanol extractives of Magnolia obovata Thunb. contained with magnonol, honokiol, dihydroxybiphenyl ether, 0.9%, 0.3% and 0.24%, respectively.

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Unrecorded causal organisms of Korean powdwery (II) (한국산 미기록 백삽병균류에 관한 연구 2)

  • 이호준;이배함
    • Korean Journal of Microbiology
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    • v.7 no.1
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    • pp.22-28
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    • 1969
  • Twenty-nine specimens of the infected plans were collected from areas through the country since 1967 to 1968. We report here four unrecorded causla organisms of powdery and their hosts which were identified in this work. The results as as follows : 1. Microsphaera diffusa Cooke et Peck (M.magnoliae Sawoda) (Host:Magnolia obovata Thunb.) 2. Sphaerotheca humili (de Condolle0Burill. (Host: Spirea sp.) 3. Phyllactinea fraxini (de Condolle)Homma. (Host : Betuls sp.) 4. Uncinula sengorui.Salmon.(Host : Celastrus orbiculatus, Thunb.) * Six unrecorded host 1. Altemisia japonica. Thunb. (Pathogen : Erysiohe cichoracearum DC.) 2. Aster tataricus. L. (Pathogen :Sohaerotheca fuliginea (Schlechtendahl) Poll. 3. Dohlia variabilis Defont. (Pathogen :Sphaerotheeca fuliginea (schlechtendahl) poll. 5. Helianthus ammues (Pathogen :Spherotheca fuliginea schlechtendahl) poll. 6. Solanum melangera L. (Pathogen : Erysiphe cichoracearum DC.)

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A Phenylpropanoid Glycoside as a Calcineurin Inhibitor Isolated from Magnolia obovata Thunb.

  • Lee, Won Jeong;Moon, Jae Sun;Kim, Sung In;Bahn, Yong-Sun;Lee, Hanna;Kang, Tae Hoon;Shin, Heung Mook;Kim, Sung Uk
    • Journal of Microbiology and Biotechnology
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    • v.25 no.9
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    • pp.1429-1432
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    • 2015
  • To identify plant-derived cell signaling inhibitors with antifungal properties, a twocomponent screening system using both wild-type Cryptococcus neoformans and a calcineurin mutant was employed owing to their counter-regulatory actions on the Hog1 mitogenactivated protein kinase and calcineurin pathways. Of the 2,000 plant extracts evaluated, a single bioactive compound from M. obovata Thunb. was found to act specifically on the calcineurin pathway of C. neoformans. This compound was identified as magnoloside A, and had potent antifungal activities against various Cryptococcus strains with minimum inhibitory concentration values ranging from 1.0 to 4.0 μg/ml.

The Study on Anti-obesity Activity of the Wild Plants of Jeju Island (제주 자생 식물들에 대한 항비만 효능에 대한 연구)

  • Park, Deok-Hoon;Jung, Eun-Sun;Lee, Jong-Sung;Jung, Kwang-Seon;Kim, Sae-Bom;Huh, Sung-Ran
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.33 no.3
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    • pp.175-179
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    • 2007
  • In this study, we investigated the anti-obesity activity of extracts collected from wild plants in Jeju island. The inhibitory effect of plant extracts on the differentiation of preadipocyte 3T3-L1 was examined by oil red-O staining. We found that extracts collected from 6 plants among 31 plants, namely, Aralia elata(Miq.) Seem, Polygonum multiflorum Thunberg, Artemisia asiatica, platycodon grandiflorum(Jacq.) A. Dc., Polygonum cuspidatum S. et Z., Magnolia obovata Thunb, significantly inhibited preadipocyte differentiation. Additionally, 4 plant extracts were also found to have antioxidant activities in DPPH radical scavenging assay. Taken together, these results show that 6 plant extracts suppress the differentiation of preadipocytes, suggesting the potential use of 6 plant extracts as anti-obesity agents.

The Characteristics of Vascular Plants Distributed in Royal Tomb of the Joseon Dynasty - Focused on Gwangneung - (조선왕릉에 분포하는 관속식물상의 특성 - 광릉을 중심으로 -)

  • Oh, Hyun-Kyung;Kim, Eun-Ok;You, Ju-Han
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.37 no.1
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    • pp.41-55
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    • 2019
  • The purpose of this study is to present the basic data for conservation and management of traditional landscape and ecological environment by surveying and analysing the vascular plants distributed in Gwnagneung, a royal tomb of the Joseon Dynasty. The results are as follows. The numbers of vascular plants were summarized as 446 taxa including 97 families, 274 genera, 384 species, 4 subspecies, 49 varieties and 9 forms. The planting species were 34 taxa including Ginkgo biloba L., Pinus koraiensis Siebold & Zucc., Taxus cuspidata Siebold & Zucc. and so forth. Exotic species such as Pterocarya stenoptera DC. and Magnolia obovata Thunb. need to be remove for traditional landscape management. The rare plants were 7 taxa including 2 taxa of CR(critically endangered), 2 taxa of VU(vulnerable) and 3 taxa of LC(least concerned). The Korean endemic plants were 8 taxa including Pseudostellaria coreana (Nakai) Ohwi, Chrysosplenium pilosum var. fulvum (N.Terracc.) Hara, Philadelphus schrenkii Rupr., Indigofera koreana Ohwi, Paulownia coreana Uyeki(planting), Weigela subsessilis (Nakai) L.H.Bailey, Aster koraiensis Nakai(planting) and Hosta minor (Baker) Nakai(planting). The specific plants by floristic region were 45 taxa including 2 taxa of grade V, 12 taxa of grade III, 9 taxa of grade II and 22 taxa of grade I. The naturalized plants were 25 taxa including Fallopia dumetorum (L.) Holub, Chenopodium ficifolium Smith, Amorpha fruticosa L., Galinsoga ciliata (Raf.) S.F.Blake and so forth. The target plants adaptable to climate change were 9 taxa including 1 taxon of endemic plant and 8 taxa of northern plants.