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The Study on Anti-obesity Activity of the Wild Plants of Jeju Island  

Park, Deok-Hoon (Biospectrum Life Science Institute)
Jung, Eun-Sun (Biospectrum Life Science Institute)
Lee, Jong-Sung (Biospectrum Life Science Institute)
Jung, Kwang-Seon (Skincure Cosmetics, Inc.)
Kim, Sae-Bom (Biospectrum Life Science Institute)
Huh, Sung-Ran (Biospectrum Life Science Institute)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.33, no.3, 2007 , pp. 175-179 More about this Journal
Abstract
In this study, we investigated the anti-obesity activity of extracts collected from wild plants in Jeju island. The inhibitory effect of plant extracts on the differentiation of preadipocyte 3T3-L1 was examined by oil red-O staining. We found that extracts collected from 6 plants among 31 plants, namely, Aralia elata(Miq.) Seem, Polygonum multiflorum Thunberg, Artemisia asiatica, platycodon grandiflorum(Jacq.) A. Dc., Polygonum cuspidatum S. et Z., Magnolia obovata Thunb, significantly inhibited preadipocyte differentiation. Additionally, 4 plant extracts were also found to have antioxidant activities in DPPH radical scavenging assay. Taken together, these results show that 6 plant extracts suppress the differentiation of preadipocytes, suggesting the potential use of 6 plant extracts as anti-obesity agents.
Keywords
anti-obesity; preadipocyte; differentiation; DPPH radical scavenging assay; oil red-O staining method;
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