• 한국초전도학회:학술대회논문집
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• v.16
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• pp.50-50
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• 2006

• 한국초전도학회:학술대회논문집
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• 2007.07a
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• pp.52-52
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• 2007

• 한국초전도학회:학술대회논문집
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• v.15
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• pp.53-53
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• 2005

• Progress in Superconductivity
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• v.8 no.1
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• pp.33-39
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• 2006

We have developed a second-order double relaxation oscillation SQUID(DROS) gradiometer with a baseline of 35 mm, and constructed a poorly magnetically-shielded room(MSR) with an aluminum layer and permalloy layers for magnetocardiography(MCG). The 2nd-order DROS gradiometer has a noise level of 20 $fT/{\surd}Hz$ at 1 Hz and 8 $fT/{\surd}Hz$ at 200 Hz inside the heavily-shielded MSR with a shielding factor of $10^3$ at 1 Hz and $10^4-10^5$ at 100 Hz. The poorly-shielded MSR, built of a 12-mm-thick aluminum layer and 4-6 permalloy layers of 0.35 mm thickness, is 2.4mx2.4mx2.4m in size, and has a shielding factor of 40 at 1 Hz, $10^4$ at 100 Hz. Our 64-channel second-order gradiometer MCG system consists of 64 2nd-order DROS gradiometers, flux-locked loop electronics, and analog signal processors. With the 2nd-order DROS gradiometers and flux-locked loop electronics installed inside the poorly-shielded MSR, and with the analog signal processor installed outside it, the noise level was measured to be 20 $fT/{\surd}Hz$ at 1 Hz and 8 $fT/{\surd}Hz$ at 200 Hz on the average even though the MSR door is open. This result leads to a low noise level, low enough to obtain a human MCG at the same level as that measured in the heavily-shielded MSR. However, filters or active shielding is needed fur clear MCG when there is large low-frequency noise from heavy air conditioning or large ac power consumption near the poorly-shielded MSR.

• Proceedings of the KIEE Conference
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• 2004.07d
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• pp.2685-2686
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• 2004

심자도(Magnetocardiography: MCG)는 심장에서 발생하는 자기신호로 크기가 수 pico Tesla에서 수 femto Tesla 정도로 지구 자기에 비하여 $10^{-6}{\sim}10^{-10}$ 정도로 매우 작기 때문에 보통 3층의 차폐 막 구조로 되어 있는 자기차폐실을 사용하여 외부 잡음을 줄인다. 그러나 자기차폐실의 비용이 크기 때문에, 자기차폐실의 비용을 줄이고 다양한 신호처리를 병행하여 신호대 잡음비를 높이고 있다. 본 논문에서는 1Giga FLOPS (FLoating point Operationals Per Second)의 부동 소숫점 연산능력을 가진 TMS320C6701을 사용하여 실시간 신호처리가 가능한 신호처리 시스템을 설계하였다. 개발된 DSP 보드는 PCI-bus 기반으로 설계하여 신호 측정 컴퓨터에 내장이 가능하도록 하였다. 프로그램과 데이터 처리를 위한 외부 메모리를 장착하였고, PCI 콘트롤러를 갖추어 PC 와의 대용량 메모리 공유가 가능하도록 하였다. 제작된 DSP 보드를 사용하여, 심자도 신호에서 실시간으로 적응 잡음 소거 및 필터링을 구현하여 신호대 잡음비의 향상을 확인할 수 있었다.

• Progress in Superconductivity
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• v.9 no.1
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• pp.40-44
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• 2007

We investigated signal-to-noise ratios (SNRs) of magnetocardiography (MCG) signals using the first-order and the second-order gradiometers of different baselines. The MCG signals were recorded using a measurement system with 61 magnetometers which measured the normal magnetic component to the chest surface. The distance between the chest surface and the bottom of the dewar was changed from 0 cm to 15 cm, and the MCGs were measured for each distance. By subtracting the other signals (distance = 1 to 15 cm) from the reference signal (distance =0 cm), we could simulate the first-order and the second-order gradiometer signals with various baselines. In addition, to evaluate the reproducibility of the simulation, we fabricated the wire wound first-order and second-order gradiometers which measured a normal magnetic component to the chest surface. The baselines of the first-order gradiometers were, respectively, 50 mm, 70 mm and 100 mm and the baseline of the second-order gradiometer was 50 mm. Using these gradiometers, we recorded the MCG signal and compared the SNR between the simulation and the measurement.

• Journal of Acupuncture Research
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• v.22 no.5
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• pp.111-120
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• 2005

Objectives : The aim of this study is to investigate the effect of acupuncture stimulation on the relationship of change in magnetocardiography (MCG). Methods : For this purpose, 30 heart deficiency volunteers were acupunctured at Shinmun (HA7) and Naegwan (PC6) acupoint. Then, we measured and observed the change of frequency parameters in MCG. Results : In the mean frequency, during and after acupuncture treated groups of PC6 were decreased the activity of $f\;_{mean-max}$ compared to the control group. In the median frequency, during the acupuncture treated group of PC6 was decreased the activity of $f\;_{median-max}$ compared to the control group. Conclusion : These results suggested that acupuncture stimulation plays an important role to the activities of MCG.

• Progress in Superconductivity
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• v.8 no.2
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• pp.164-168
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• 2007

We developed a SQUID magnetometer based on Double Relaxation Oscillation SQUID(DROS) for measuring magnetocardiography(MCG). Since DROS provides a 10 times larger flux-to-voltage transfer coefficient than the conventional DC-SQUID, simple flux-locked loop electronics could be used for SQUID operation. Especially, we adopted an external feedback to eliminate the magnetic coupling with adjacent channels. When the DROS magnetometer was operated inside a magnetically shielded room, average magnetic field noise was about 5 $fT/^{\surd}Hz$ at 100 Hz. Using the DROS magnetometer, we constructed a multichannel MCG system. The system consisted of 61 magnetometers are arranged in a hexagonal structure and measures a vertical magnetic-field component to the chest surface. The distance between adjacent channels is 26 mm and the magnetometers cover a circular area with a diameter of 208 mm. We recorded the MCG signals with this system and confirmed the magnetic field distribution and the myocardinal current distribution.

• Progress in Superconductivity
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• v.7 no.1
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• pp.28-35
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• 2005

We propose a method to measure atrial arrhythmias (AA) such as atrial fibrillation (Afb) and atrial flutter (Afl) with a SQUID magnetocardiograph (MCG) system. To detect AA is one of challenging topics in MCG. As the AA generally have irregular rhythm and atrio-ventricular conduction, the MCG signal cannot be improved by QRS averaging; therefore a SQUID MCG system having a high SNR is required to measure informative atrial excitation with a single scan. In the case of Afb, diminished f waves are much smaller than normal P waves because the sources are usually located on the posterior wall of the heart. In this study, we utilize an MCG system measuring tangential field components, which is known to be more sensitive to a deeper current source. The average noise spectral density of the whole system in a magnetic shielded room was $10\;fT/{\surd}Hz(a)\;1\;Hz\;and\;5\;fT/{\surd}Hz\;(a)\;100\;Hz$. We measured the MCG signals of patients with chronic Afb and Afl. Before the AA measurement, the comparison between the measurements in supine and prone positions for P waves has been conducted and the experiment gave a result that the supine position is more suitable to measure the atrial excitation. Therefore, the AA was measured in subject's supine position. Clinical potential of AA measurement in MCG is to find an aspect of a reentry circuit and to localize the abnormal stimulation noninvasively. To give useful information about the abnormal excitation, we have developed a method, separative synthetic aperture magnetometry (sSAM). The basic idea of sSAM is to visualize current source distribution corresponding to the atrial excitation, which are separated from the ventricular excitation and the Gaussian sensor noises. By using sSAM, we localized the source of an Afl successfully.