• Journal of Magnetics
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• 제20권2호
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• pp.133-137
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• 2015

This study was conducted to determine the effects of repetitive transcranial magnetic stimulation (rTMS) integrated mirror therapy on the gait of post-stroke patients. Thirty patients who were six months post-stroke were assigned to either the experimental group (n = 15) or the control group (n = 15). Stroke patients in the experimental group underwent rTMS and mirror therapy for the lower limbs, while those in the control group underwent rTMS and sham therapy. Participants in both groups received therapy five days per week for four weeks. A significant difference in post-training gains for the single support phase, step length, stride length and velocity was observed between the experimental group and the control group (p < 0.05). The experimental group showed a significant increment in the single support phase, step length, stride length, swing phase, velocity, cadence, double support phase and step width as compared to pre-intervention (p < 0.05). The control group showed a significant increment in step length, velocity, cadence and step width compared to preintervention (p < 0.05). Further investigation of the availability and feasibility of rTMS integrated mirror therapy for post-stroke patients as a therapeutic approach for gait rehabilitation is warranted.

• 정신신체의학
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• 제18권1호
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• pp.3-10
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• 2010

뚜렛 증후군은 주로 아동기에 발생하는 만성적인 운동 및 음성 틱을 주소로 하는 질환이다. 기저핵-시상-피질 회로에서의 이상이 비자발성 틱의 병태생리에 중요한 역할을 하는 것으로 생각된다. 뚜렛 증후군은 흔히 주의력 결핍 과잉행동장애나 강박장애와 병존한다. 경두개 자기자극술은 연구용으로 많이 사용되는 신경생리학적 기법이다. 이 기법이 피질의 활성을 변화시킬 수 있다는 증거들이 많아서, 반복적 경두개 자기자극술은 피질의 활성도를 바꾸어서 결과적으로 내재한 서로 연결된 피질-피질하 회로에 영향을 주기 위하여 치료적 목적으로도 사용된다. 우리는 본 논문에서 경두개자극술의 여러 신경생리학적 변인들과 임상적 응용에 관하여 기존의 연구보고들을 고찰하여 보고자 한다.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.352-355
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• 2002

The purpose of this study was to investigate whether or not acupuncture of GB34 produces a significant response of the modulation of somatomotor areas by functional magnetic resonance imaging (fMRI) study. The acupoint, GB34, located in the back of the knee, is known to be effective in recovering motor function after stroke. Using 3T MRI scanner, functional MR imaging of the whole brain was performed in 12 normal healthy subjects during two stimulation paradigms; acupuncture manipulation on GB 34 and sham points. This study investigates the activation of the mortor cortex elicited by a soft and an intensified stimulation of GB 34. Three different paradigms were carried out to detect any possible modulation of the Blood Oxygenation Level Dependent (BOLD) response in the somatomortor area to motor stimulation through acupuncture. Group analysis from seven individuals showed that bilateral sensorimotor areas (BA 3,4,6 and 7) showed stimulation related BOLD signal contrast of approximately 6% whereas very few areas were activated when sham stimulation is given. The present study shows that acupuncture fMRI study can be safely conducted in 3T MRI environment, and acupuncture stimulation in GB34 modulates the cortical activities of the somatomotor area in human. The present findings may shed light on the CNS mechanism of motor function by acupuncture and form a basis for future investigations of motor modulation circuits in the stroke patients.

• Journal of Magnetics
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• 제19권1호
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• pp.32-36
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• 2014

The purpose of this study was to investigate the effect of pulsed magnetic field (PMF) and low frequency low level laser (LFLLL) stimuli on acupoint LI4 (Hegu) using photoplethysmography (PPG). Our PMF system was designed to generate maximum intensity of 0.20 T at a transition time of 0.16 ms, with pulse intervals of 1 Hz. The diode laser with wavelength of 650 nm and power of 5 mW was also employed. It was observed the change of the pulsating blood volume through measuring PPG signals from both hands. These results imply that stimulating acupoint LI4 with PMF and LFLLL improves the circulation of peripheral vascular system. In particular, PMF stimulation brings a big improvement of the blood flow even with short term stimulation of 3-4 minutes compared to LFLLL stimulus.

• 대한의용생체공학회:의공학회지
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• 제11권1호
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• pp.1-4
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• 1990

Functional neuromuscular stimulation(FNS)를 사용하여 하반선마비사가 앉은 상태에서부터 일어나 균형을 유지할 수 있도록 하기 위하여 FNS의 자동제어 시스댐을 개발하였다. Output feedback gain matrix를 최적제어이론을 사용하여 계산하기 위하여 비선형 선체모델을 직립위치에 대하여 선형화하였다. 제어기는 측정된 output에 의하여 매순간 각 선체조인트에 필요한 torque할 계산 하며, 이 조인트 torque는 근육이 최소한의 에너지를 사용하게끔 각 단육에 배분된다. 컴퓨터 시뮬레이션결과, 이 제어 시스템을 사용하여 각 조인트가 약 45도 정도 구부버진 상태에서 부터 직립위치를 회복할 수 있으며 팔의 움직임으로 대표되는 외부로부터의 방해를 반았블 때에도 직립 위치를 자동적으로 유지할 수 있었다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2006년도 하계종합학술대회
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• pp.855-856
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• 2006

Magnetic nerve stimulation treatment is much backward real condition than other field. Specially, successful medical treatment introduction of magnetic field (MF) can was refered long ago in Avicenna's work, and is thought as age of medicine magnetology development recently. These development is achieved through biologist and biophysicist and clinician's joint effort, but, new mountings and relationship air tassel are developed steadily. Magnetic nerve stimulation treatment field designs treatment system by each function during long wave high-amplitude (traditional magneto therapy of greatly great that strong that) short time that CMF, VMF, PMF field etc. are representative but are HPMT technology in this research and manufacture and special quality did comparative analysis.

• 한국정보통신학회논문지
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• 제14권5호
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• pp.1209-1216
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• 2010

당뇨 합병증 등으로 인한 말초혈류 및 신경장애, 수족냉증 및 손가락 관절염, 통증 질환이 증가하고 있으며, 이러한 문제를 개선할 수 있는 손가락 질환 전용 치료기기가 전무한 상태로 이와 관련된 치료기의 개발이 필요하다. 본 연구에서는 시변 미약자기장을 이용하여 비침습적으로 말초혈류/신경개선과 손가락 류마티스 치료를 위한 솔레노이드 원통형 코일을 제작하고, 다양한 치료목적에 사용하기 위해서 3가지 자극모드(N, S, N/S)와 자극주파수(0.25, 0.5, 1hz)를 선택할 수 있는 시스템을 설계하였다. 자속밀도 측정 프로브를 솔레노이드의 중심에서부터 거리를 0 ~ 3cm 단계로 자극방식과 주파수별로 자속밀도를 측정하였다. 자속밀도를 측정한 결과, 모든 자극방식과 주파수에서 솔레노이드 내부의 중심(0cm)에 근접할수록 자속밀도가 급격히 증가하였다. 솔레노이드 중심 자속밀도는 N자극 (294.3mT)과 S자극(293.8mT)에서는 1Hz, N/S자극(275.4mT)에서는 0.25Hz에서 가장 높게 측정되었다. 본 논문에서는 다양한 패턴과 강도의 자기장을 이용하여 다양한 손가락 질환을 치료할 수 있는 솔레노이드형 치료기기를 개발하였다. 솔레노이드 내부 자속밀도를 측정함으로써 손가락 말초질환 개선을 위한 미약자기장 시스템의 임상 적용 가능성을 확인하였다.

• 수면정신생리
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• 제28권1호
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• pp.2-5
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• 2021

Hyperarousal or increased brain excitability is thought to play a key role in the pathophysiology of insomnia. Neuromodulation techniques are emergent complementary therapies for insomnia and can improve sleep by modulating cortical excitability. A growing body of literature support the idea that neuromodulation can be effective in improving sleep or treating insomnia. Recent evidence has revealed that neuromodulation methods can improve objective and subjective sleep measures in individuals with insomnia, although effects vary according to protocol. Different mechanisms of action might explain the relative efficacy of neuromodulation techniques on sleep outcomes. Further research testing different stimulation parameters, replicating existing protocols, and adding standardized sleep-related outcomes could provide further evidence on the clinical utility of neuromodulation techniques.

• Annals of Clinical Neurophysiology
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• 제8권1호
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• pp.29-35
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• 2006

Background: Transcranial magnetic stimulation (TMS) is a non-invasive diagnostic method particularly suited to investigation the long motor tracts. The clinical value of TMS in most spinal cord diseases has still to be made. Diagnostic value of magnetic motor evoked potential (MEP) parameters in intramedullary spinal cord lesions was investigated. Methods: MEP elicited by TMS was recorded in 57 patients with clinically and radiologically defined intramedullary myelopathy. Twenty five patients with cervical myelopathy (CM) and 32 thoracic myelopathy (TM) were included. Recordings were performed during resting and minimal voluntary contraction at both abductor pollicis brevis (APB) and tibialis anterior (TA) muscles. Stimulation threshold(ST), amplitude, and central motor conduction time (CCT) were measured at resting and facilitated conditions. CCT was calculated by two means; central motor latency (CML)-M using magnetic transcranial and root stimulation, and CML-F using electrical F-wave study. The results were compared between patient groups and 10 normal control group. Results: Facilitated mean ST recorded at TA was elevated in both CM and TM compared with control group. Resting mean CML-M at TA was significantly prolonged in both CM and TM, and CML-M was absent or delayed in 37.1% of CM and 8% of TM at APB with facilitation. Facilitated mean MEP amplitude at ABP was lower in CM than in TM, while MEP/M ratios were not different significantly between groups. Conclusions: Magnetic motor evoked potential has diagnostic value in intramedullary myelopathy and localizing value in differentiating between CM and TM by recording at APB and TA. It is a noninvasive way to investigate the functional status of motor tracts of spinal cord.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2014년도 자성 및 자성재료 국제학술대회
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• pp.158-160
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• 2014