• 한국자기공명학회:학술대회논문집
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• 한국자기공명학회 1999년도 하계총회 및 제15회 자기공명 학술발표회
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• pp.10-10
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• 1999

• 한국자기공명학회:학술대회논문집
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• 한국자기공명학회 1999년도 하계총회 및 제15회 자기공명 학술발표회
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• pp.30-30
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• 1999

• 한국자기공명학회:학술대회논문집
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• 한국자기공명학회 2002년도 제20회 학술발표회
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• pp.3-4
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• 2002

• 한국자기공명학회:학술대회논문집
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• 한국자기공명학회 2002년도 International Symposium on Magnetic Resonance
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• pp.49-49
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• 2002

• 한국자기공명학회논문지
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• 제11권1호
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• pp.42-47
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• 2007

Several hydrotalcite compounds calcined with different temperature for applications in a chlorine resistant textile were prepared, and its structural changes in dependence on the temperature were studied by using $^{27}Al$ solid-state nuclear magnetic resonance(NMR) spectroscopy. We found that the Al coordination was partly lowered from octahedral to tetrahedral site as the calcined temperature goes up. And we also investigated the hydrotalcite-treated textile for chlorine resistance by using $^{27}Al$ solid-state NMR spectroscopy.

• Investigative Magnetic Resonance Imaging
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• 제22권1호
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• pp.26-36
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• 2018

Purpose: Children born with single ventricle physiology demonstrate poor growth rate and suffer from malnutrition, which lead to increased morbidity and mortality in this population. We assume that an anabolic steroid, oxandrolone, will promote growth in these infants by improving myocardial energy utilization. The purpose of this paper is to study the efficacy of oxandrolone on myocardial energy consumption in these infants. Materials and Methods: We modeled single ventricle physiology in a lamb by prenatally shunting the aorta to the pulmonary artery and then postnatally, we monitored cardiac energy utilization by quantitatively measuring the first order reaction rate constant, $k_f$ of the creatine-kinase reaction in the heart using magnetization transfer $^{31}P$ magnetic resonance spectroscopy, home built $^1H/^{31}P$ transmit/receive double tuned coil, and transmit/receive switch. We also performed cine MRI to study the structure and dynamic function of the myocardium and the left ventricular chamber. The spectroscopy data were processed using home-developed python software, while cine data were analyzed using Argus software. Results: We quantitatively measured both the first order reaction rate constant and ejection fraction in the control, shunted, and the oxandrolone-treated lambs. Both $k_f$ and ejection fraction were found to be more significantly reduced in the shunted lambs compared to the control lambs, and they are increased in oxandrolone-treated lambs. Conclusion: Some improvement was observed in both the first order reaction rate constant and ejection fraction for the lamb treated with oxandrolone in our preliminary study.

• Investigative Magnetic Resonance Imaging
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• 제12권2호
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• pp.107-114
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• 2008

목적 : 3T MR 기기를 이용하여, 췌장 주위에 발생한 낭성 종양에 대하여, 생체내, 그리고 생체외 생체내 자기공명분광법(magnetic resonance spectroscopy: MRS)를 획득한 후, 생체외 핵자기공명 (nuclear magnetic resonance, NMR) 스펙트럼을 기준으로 비교함으로써, 낭성 종양의 감별 진단에 있어 MRS의 적용 가능성을 알아보고자 하였다. 대상 및 방법 : 췌장 주위에 발행한 12예의 낭성 종양(점액성 낭성 종양=5, 췌담관내 유두종=5, 가성 낭종=1, 및 림프관종 n=1)을 대상으로 3.0T 생체내, 생체외 양성자 MRS 및 9T NMR 스펙트럼을 획득하였다. NMR의 피크와 상응하는 생체내, 생체외 양성자 MRS에서 관찰되는 피크의 존재유무를 알아보았으며, 특정 질환을 예측하는 피크에 대하여 알아보았다. 결과 : 생체내 MRS는 NMR과 민감도 29.6%, 특이도 82.6% 그리고, 67.7%의 정확도를 보였으며 (p=0.096, McNemar test), 생체외 MRS는 생체내 MRS는 민감도 57.1%, 특이도 92.6%, 그리고, 82.3%의 정확도를 보였다 (p = 0.362, McNemar test). 질병간의 스펙트럼의 차이는 NMR에서 췌담관내 유두종의 경우에서 점액성 낭성 종양에 비해 3.5-4.0 ppm에서 유의하게 많은 피크를 보였다 (p=0.026). 결론 : 결론적으로, NMR 이용한 화학물질 분석은 낭성 종양의 감별 진단에 도움이 될 가능성이 있는 기법으로 생각되지만, 생체내 및 생체외 MRS는 임상에 적용되기 위해서는 많은 기술적 발전을 필요로 하는 것으로 생각된다.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.25-25
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• 2003

Purpose： In order to characterise primary central nervous system Iymphomas (PCNSL) and to evaluate if 1H spectroscopy improves the preoperative differential diagnosis of other diseases. Method： We reviewed 11 MR imaging and 7 MR spectroscopy of 9 patient with Iymphoma confirmed by stereotatic biopsy.

• 한국자기공명학회논문지
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• 제19권3호
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• pp.124-131
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• 2015

Hyperpolarization methods are the most emerging techniques in the field of magnetic resonance (MR) researches since they make a contribution to overcoming sensitivity limitation of MR spectroscopy and imaging, leading to new fields of researches, real-time in vivo metabolic/molecular imaging and MR analysis of chemical/biological reactions in non-equilibrium conditions. Make use of enormous signal enrichments, it becomes feasible to investigate various chemical and biochemical systems with low ${\gamma}$ nuclei in real-time. This review deals with the theoretical principals of common hyperpolarization methods and their experimental features. In addition, more detailed theories, mechanisms, and applications of dissolution dynamic nuclear polarization (D-DNP) are discussed.

• 한국자기공명학회논문지
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• 제6권2호
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• pp.142-154
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• 2002

One of the oldest, still unsolved, and often ignored problems in magnetic resonance remains the issue of how to observe undistorted, normal one-dimensional spectra where the frequencies and their relative intensities represent faithfully the distribution of spins and sites in the sample within the magnet. Often distortions in these parameters are accepted, as the price of sensitivity enhancement, or because it is unclear just how these distortions might be avoided. Surprisingly enough, the problem is exacerbated by the use of modern techniques of pulsed Fourier transform NMR. Noise spectroscopy is an approach to solving the problem of distorted NMR spectra, which is largely under appreciated; it promises virtually "unlimited" distortionless bandwidths without costly hardware investments. Nonetheless, its exploitation remains limited. We will discuss why noise spectroscopy belongs in the arsenal of tricks spectroscopists should be aware of, show examples where its use is essential if accurate, quantitative NMR is to be expected, and discuss some recent approaches which extend its applicability yet further, particularly in solid state NMR and in applications to quadrupolar nuclear spins.