• Journal of radiological science and technology
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• v.20 no.1
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• pp.29-34
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• 1997

For radiological test in soft tissue or neighboring part with same signal intensity, proper test method and equipment shall be selected as needed. In case of female pelvic cavity, ultrasonography or computed tomography alternatively used, but MRI can be more usefully applied to design treatment method or operation plan by improving the diagnostic accuracy and careful observation of lesion characteristics. Magnetic Resonance Imaging using recently developed Enteral MRI contrast media can acquire more diagnostic information than using only intravenous contrast media. Thus this study attempted to examine the utility of anatomic structure and diagnostic acquisition by imaging the female pelvic cavity using Enteral MRI contrast media. As a result of analyzing magnetic resonance Imaging after administering Enteral MRI contrast media to pelvic cavity suspect patients, more diagnostic information media could be acquired than only using Intravenous contrast. Expecially, in the diagnosis of lesion position, shape, distinction from neighboring tissues it is thought that external Enteral MRI contrast media should be used.

• Journal of the Korean Magnetic Resonance Society
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• v.24 no.1
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• pp.30-37
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• 2020

Quantitative nuclear magnetic resonance (qNMR) has been gaining attention as a purity assessment method. In particular, qNMR is recognized as the primary method to realize the Internal System of Units (SI) in organic analysis. The capability of quantitative analysis is recognized as the beginning of NMR development. NMR signals are proportional to the number of nuclei and qNMR has been used in various fields, such as metabolomics and food and pharmaceutical analysis. However, careful sample preparation and thorough optimization of measurement parameters are required to obtain accurate and reliable results. In this review, quantitative methods used in qNMR are discussed, and the important factors to be considered also introduced. The recent development of qNMR techniques including combination with chromatography and, multidimensional NMR are also presented.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.49 no.6
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• pp.421-430
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• 2000

This paper describes an optimal design method which is applied a weighted least square (WLS) method for Magnetic Resonance Imaging (MRI) system. An optimal design approach is presented for a homogeneity superconducting magnet with the superconducting active shield especially for a magnetic resonance imaging system. The WLS is used to obtain the optimal configurations using the least amount and minimum volume of conductor, exhibiting the smallest level of field inhomogeneity and resulting in the least level of stray field. The proposed model is used to design a multiple-shield configuration for a 1.5 T MRI magnet. The field homogeneity is required less than 5 gauss stray field contour within 4m axially and 3m radially from origin. The designed magnet with the actively magnetic shielding coil out of main coils is analyzed by FEM and theoretical analysis method, investigated the field homogeneity.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.32 no.8
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• pp.654-659
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• 2008

This paper is to suggest a concept design of the permanent magnet type magnetic resonance imaging (MRI) device based on the parameter optimization method. Pulse currents in the gradient coils will introduce the effect of eddy currents in the ferromagnetic material, which will worsen the quality of imaging. In order to equalize the magnetic flux in the MRI device for good imaging, the eddy current effect in the ferromagnetic material must be taken into account. This study attempts to use the design of experiment (DOE) and the response surface method (RSM) for equalizing the magnetic flux of the permanent magnet type MRI device using that the magnetic flux can be calculated directly using a commercial finite element analysis package. As a result, optimal shapes of the pole and the yoke of the PM type MRI device can be obtained. The commercial package, ANSYS, is used for analyzing the magnetic field problem and obtaining the resultant magnetic flux.

• Journal of Electrical Engineering and Technology
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• v.8 no.4
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• pp.799-807
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• 2013

The proper equivalent circuit is newly presented for electro-magnetic resonance based wireless power transfer. Based on the proposed equivalent circuit of open-ended helical antennas, the parameter identification of helical antennas can be well derived for highly efficient wireless power transfer. The well-established equivalent circuit in high frequency ranges is developed for analyzing a resonance enhanced-electromagnetic coupling helical antennas and the unknown parameters for helical antennas are identified by experiments. The effectiveness based on the proposed equivalent circuit is verified through experiments.

• Journal of the Korean Magnetic Resonance Society
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• v.10 no.1
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• pp.1-37
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• 2006

General expressions for solid state NMR lines are described for transitions under static, magic angle spinning, and variable angle spinning conditions in the case where the principal axis system for the anisotropic chemical shift tensor is noncoincident with that of the quadrupole coupling tensor. It is demonstrated that solid state NMR powder pattern simulation program VMAS based on the conventional grid point method of integrating over the Euler angle space is fast enough in comparison with the POWDER simulation package and Gauss-point method.

• Journal of the Korean Magnetic Resonance Society
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• v.3 no.1
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• pp.36-43
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• 1999

We present a pulse shape tailored for broadband decoupling for a system of spin-1/2's with scalar couplings as well. In crafting the pulse shape Coherent Averaging Theory and Fourier expansion method are used. The Fourier expansion coefficients are optimized numerically by applying the Simulated Annealing Method. The decoupling performance of the shaped pulse thus designed is then compared with the well-known composite pulse sequence, DIPSI-2. It is shown that the shaped pulse performs well even at the conditions where the DIPSI sequence begins to fail.

• Journal of the Korean Magnetic Resonance Society
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• v.11 no.2
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• pp.115-121
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• 2007

A new quantitative analysis of chloride by the HERETIC NMR method which does not need internal or external references was described. The results showed that the use of HERETIC peak corresponding $500\;{\mu}g/mL$ of chloride calibration showed less than 4 % standard deviations from 50 to $5000\;{\mu}g/mL$ range of chloride concentrations.

• Bulletin of the Korean Chemical Society
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• v.33 no.6
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• pp.1890-1894
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• 2012

Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been implicated in the pathogenesis of rheumatoid arthritis, which is angiogenesis dependent. Antibody-based molecular imaging improves targeting, and antibody radiolabeling is useful for monitoring biological events $in$ $vivo$ $via$ PET or SPECT. We investigated the potential of molecular imaging to diagnose arthritis with VEGFR-2 $in$ $vivo$. The $^{123}I$-VEGFR-2 antibody was prepared by the iodogen tube method. The radioligand was injected into arthritic mice, and micro SPECT/CT was performed. The arthritic mice were examined by 4.7-T MRI and immunohistochemistry. The $^{123}I$-VEGFR-2 antibody showed high uptake in the arthritic region at 1 h postinjection on SPECT/CT but no uptake in the control animals after radioligand injection. In MR images, the arthritic tissue of the mice was correlated with regions labeled by the $^{123}I$-VEGFR-2 antibody. Immunohistochemical localization showed markedly increased expression of VEGFR-2 in the endothelial cells, fibroblasts, and macrophages of the arthritic mice.

• Investigative Magnetic Resonance Imaging
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• v.25 no.3
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• pp.141-155
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• 2021

Purpose: To develop a 3D magnetic resonance fingerprinting (MRF) method for application in high resolution knee cartilage PD, T₁, T₂ mapping. Materials and Methods: A novel 3D acquisition trajectory with golden-angle rotating radial in k_xy direction and interleaved echo planar imaging (EPI) acquisition in the k_z direction was implemented in the MRF framework. A centric order was applied to the interleaved EPI acquisition to reduce Nyquist ghosting artifact due to field inhomogeneity. For the reconstruction, singular value decomposition (SVD) compression method was used to accelerate reconstruction time and conjugate gradient sensitivity-encoding (CG-SENSE) was performed to overcome low SNR of the high resolution data. Phantom experiments were performed to verify the proposed method. In vivo experiments were performed on 6 healthy volunteers and 2 early osteoarthritis (OA) patients. Results: In the phantom experiments, the T₁ and T₂ values of the proposed method were in good agreement with the spin-echo references. The results from the in vivo scans showed high quality proton density (PD), T₁, T₂ map with EPI echo train length (N_ETL = 4), acceleration factor in through plane (R_z = 5), and number of radial spokes (N_spk = 4). In patients, high T₂ values (50-60 ms) were seen in all transverse, sagittal, and coronal views and the damaged cartilage regions were in agreement with the hyper-intensity regions shown on conventional turbo spin-echo (TSE) images. Conclusion: The proposed 3D MRF method can acquire high resolution (0.5 mm³) quantitative maps in practical scan time (~ 7 min and 10 sec) with full coverage of the knee (FOV: 160 × 160 × 120 mm³).