• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.6A
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• pp.556-562
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• 2006

In this paper, macro diversity coding methods are proposed to efficiently transmit broadcast packet data over mobile cellular networks based on OFDM. In the method, cells are divided into multiple cell groups which transmit one of two orthogonal branches in a transmit diversity code. Furthermore, a coded packet is partitioned into the subblocks for which different cell group combinations are assigned to transmit two different branches. The methods extend the cell coverage at the same transmit power due to the transmit diversity of each symbol and coding diversity obtained through different fading statistics over the subblocks.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.5
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• pp.1291-1300
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• 2004

Baicalin, a biologically active flavonoid form the roots of Scutallaria baicalensis (Skullcap), have been reported to not only function as anti-oxidants but also cause anticancer effect. We investigated the mechanism of baicalin-induced cytotoxicity and the macro scale gene expression analysis in leukemia cell line, HL-60 cells. Baicalin (10 μM) were used to treat the cells for 6h, 12h, 24h, 48h and 72h. In a human cDNAchip study of 65,000 genes evaluated 6, 12, 24, 48. 72 hours after treated with Baicalin in HL-60 cells. Hierarchical cluster against the genes which showed expression changes by more than two fold. One hundred one genes were grouped into 6 clusters according to their profile of expression by a hierarchical clustering algorithm. For genes differentially expressed in response to baicalin treatment, we tested functional classes based on Gene Ontology (GO) terms. This study provides the most comprehensive available survey of gene expression changes in response to baicalin treatment in HL-60 cell line.

• ETRI Journal
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• v.37 no.5
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• pp.856-866
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• 2015

A heterogeneous network (HetNet) is a network topology composed by deploying multiple HetNets under the coverage of macro cells (MCs). It can improve network throughput, extend cell coverage, and offload network traffic; for example, the network traffic of a 5G mobile communications network. A HetNet involves a mix of radio technologies and various cell types working together seamlessly. In a HetNet, coordination between MCs and small cells (SCs) has a positive impact on the performance of the networks contained within, and consequently on the overall user experience. Therefore, to improve user-perceived service quality, HetNets require high-efficiency network protocols and enhanced radio technologies. In this paper, we introduce a 5G HetNet comprised of MCs and both fixed and mobile SCs (mSCs). The featured mSCs can be mounted on a car, bus, or train and have different characteristics to fixed SCs (fSCs). In this paper, we address the technical challenges related to mSCs. In addition, we analyze the network performance under two HetNet scenarios-MCs and fSCs, and MCs and mSCs.

• Journal of the Korean Society for Advanced Composite Structures
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• v.2 no.3
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• pp.1-11
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• 2011

The typical truss-lattice material successively packed by repeated cubic symmetric unit cells consists of sub-elements (SE) proposed in this study. The representative continuum model for this truss-lattice material such as the effective strain and stress relationship can be formulated by the homogenization procedure based on the notation of averaged mechanical properties. The volume fractions of micro-scale struts have a significant influence on the effective strength as well as the relative density in the lattice plate with replicable unit cell structures. Most of the strength contribution in the lattice material is induced by axial stiffness under uniform stretching or compression responses. Therefore, continuum based constitutive models composed of homogenized member stiffness include these mechanical characteristics with respect to strength, internal stress state, material density based on the volume fraction and even failure modes. It can be also recognized that the stress state of micro-scale struts is directly associated with the continuum constitutive model. The plastic flow at the micro-scale stress can extend the envelope of the analytical stress function on the surface of macro-scale stress derived from homogenized constitutive equations. The main focus of this study is to investigate the basic topology of unit cell structures with the cubic symmetric system and to formulate the plastic models to predict pressure dependent macro-scale stress surface functions.

• Journal of Internet Computing and Services
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• v.24 no.1
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• pp.1-7
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• 2023

Recently, the technology of device-to-device(D2D) communication has been receiving big attention to improve the system performance since the amount of high quality/large capacity data traffic from smart phones and various devices of Internet of Things increase rapidly in 5G/6G based next generation cellular networks. However, even though the system performance of macro cells increase by reusing the frequency, the performance of macro user equipments(MUEs) decrease because of the strong interference from D2D user equipments(DUEs). Therefore, this paper proposes a dynamic channel management(DCM) scheme for DUEs to guarantee the performance of MUEs as the number of DUEs increases in next generation downlink cellular networks. In the proposed D2D DCM scheme, macro base stations dynamically assign subchannels to DUEs based on the interference information and signal to interference and noise ratio(SINR) of MUEs. Simulation results show that the proposed D2D DCM scheme outperforms other schemes in terms of the mean MUE capacity as the threshold of the SINR of MUEs incareases.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.7
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• pp.2993-2999
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• 2014

Saccharina japonica is a family member of Phaeophyceae (brown macro-alga) and extensively cultivated in China, Japan and Korea. Here, the potential anti-cancer effect of n-hexane fraction of S. japonica was evaluated in SK-Hep1 human hepatocellular carcinoma cells. The N-hexane fraction reduced cell viability and increased the numbers of apoptotic cells in a both dose- and time-dependent manner. Apoptosis was activated by both caspase-dependent and independent pathways. The caspase-dependent cell death pathway is mediated by cell surface death receptors and activated caspase-8 amplified the apoptotic signal either through direct activation of downstream caspase-3 or pro-apoptotic proteins (Bad, Bax and Bak) subsequently leading to the release of cytochrome c. On the other hand, caspase-independent apoptosis appeared mediated by disruption of mitochondrial membrane potential and translocation of AIF to the nucleus where they induced chromatin condensation and/or large-scale DNA fragmentation. In addition, the n-hexane fraction induced endoplasmic reticulum (ER)-stress and cell cycle arrest. The results suggested that potential anti-cancer effects of n-hexane extract from S. japonica on SK-Hep1 cells.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38A no.6
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• pp.520-527
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• 2013

In this paper, a joint cell grouping and user association technique proposed for a semi-dynamic grouped network MIMO in a clustered heterogeneous cellular network (HCN). With the conventional macro BSs, small cells are being overlaid to increase a spectral efficiency per area and these small cells are expected to be concentrated to support exponentially increasing data traffic in hot spot areas. The main culprits of performance degradation in the clustered HCN are interference and load imbalance. The proposed scheme jointly handles them to maximize a proportional-fair metric. It is shown that the proposed technique can largely improve user average rate and proportional fairness among users than any other conventional schemes in the clustered HCN.

• Archives of Pharmacal Research
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• v.26 no.11
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• pp.960-966
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• 2003

Macrophages play an important role in host defenses by killing tumors and virus infections and producing secretory products. High mannuronic acid (HMA) containing alginate was examined to determine the mechanisms by which HMA-activated macrophages resist infection with HSV-1 and inhibit the growth of tumor cells. The ability of macro phages to resist infection with HSV-1 or to inhibit the growth of tumor cells was assessed following treatment with HMA alginate in the presence of either antibodies to various cytokines or inhibitors/scavengers of toxic macrophage products. Only antibodies to IFN-$\alpha$/$\beta$ were able to abrogate the protective effects of HMA alginate in macrophages infected with HSV-1, suggesting that the antiviral activity induced by this immunomodulator was mediated by the production of IFN-$\beta$. In contrast, anti-TNF-$\alpha$, anti-IFN and inhibitors of nitric oxide and reactive oxygen species were all able to partially abrogate HMA-induced cytostatic activity, suggesting that multiple mechanisms are involved in macrophage cytostasis. These results indicate that the HMA-induced intrinsic antiviral and extrinsic cytotoxic activites are mediated by different mechanisms.

• Natural Product Sciences
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• v.11 no.2
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• pp.58-62
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• 2005

Pygmaeopremna herbacea (Roxb.) Mold. (Verbenaceae) is a small herb or sometimes an undershrub arising from a perennial rootstock. The dry roots are dark muddy brown in colour having root nodules. Its extensively developed roots are widely used in tribal medicine. They are used as an aphrodisiac and for the treatment of gout, rheumatism and ulcers. This study deals with the detailed pharmacognostical evaluation of the dried roots and root nodules of P. herbacea which includes macro and microscopic studies, determination of physicochemical parameters and chemoprofiling of the extract using HPTLC fingerprint profiles. It was observed that the roots consist of a well developed cortical region consisting of tangentially elongated thin walled parenchymatous cells and contain polygonal stone cells as well as compound starch grains. Also the pith was parenchymatous. The HPTLC fingerprint profile of the methanolic extract showed the presence of seven major bands. Such an analysis may thus be utilized in identifying P. herbacea and in differenciating it from other species which are similar to it or are used as its adultrants/substitutes under the same vernacular name of Bharangi.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.5B
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• pp.388-403
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• 2003

RSVP was published as a resource reservation protocol to guarantee QoS for realtime applications in wired network environments. As mobile application services in wireless network environments are more popular, QoS guaranteeing problem becomes an important issue in mobile computing environments. Therefore, the researches about cooperation between RSVP and Mobile IP supporting mobility in mobile computing environments are activating today. In this paper, we propose I-MRSVP(Integrated-Mobile RSVP), a QoS guaranteed resource reservation protocol supporting the integrated mobility in mobile computing environments. I-MRSVP protocol supports the integrated mobility providing interoperability between Mobile IP-based macro cells and Cellular IP-based micro cells. To minimize resource reservation overheads, it provides efficient resource reservation functions by using the signal strength based predictive resource reservation scheme.