• Korean Journal of Veterinary Service
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• v.46 no.4
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• pp.363-368
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• 2023

Patent ductus arteriosus (PDA) in monkeys is very rare. A 9-year-old male Japanese macaque (Macaca fuscata) had an hourglass-shaped PDA with a large luminal diameter. Morphological analysis of the vessel cast and heart revealed cardiovascular pathological changes including pulmonary artery hypertension and right ventricular hypertrophy. However, left ventricle hypertrophy or left atrial enlargement were not observed. This macaque had showed no clinical signs of PDA during its lifetime. We present the first documented case of solitary PDA in a male macaque.

• Journal of Veterinary Clinics
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• v.22 no.4
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• pp.401-403
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• 2005

A seven-year old female captive Japanese macaque (Macaca fuscata) was mobbed by its cage mates and subsequently died due to trauma. An incidental finding of multiple biliary cystadenoma in the liver is herein reported. Grossly, multiple small cysts were observed throughout the surface of the liver. One particular cyst that measured $1.3\times1.2\times1.0cm$ and contained mucinous fluid was observed in the center of the liver. Microscopically the cysts were lined by biliary epithelium that varied from simple cuboidal to columnar cells. Signs of malignancy and metastasis to other organs were not observed. This is the first report of biliary cystadenoma in Japanese macaque.

• Journal of Life Science
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• v.11 no.1
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• pp.34-38
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• 2001

The cDNA encoding ribosomal protein S4(RPS 4) from an ovary cDNA library of the Japanese monkey (Macaca fuscata) was cloned and sequenced. The RPS4X gene from monkey X chromosome encodes a deduced protein of 263 amino acids and share 99.1% cDNA sequence similarity and 100% amino acid sequence identify with the human RPS4X. Rate of synonymous substitution was higher in RPS4Y than in RPS4X in comparison to the monkey and human. The ratio of synonymous and nonsynonymous substitutions per site indicated that directional selection has nor occurred in RPS4 genes. Phylogenetic analysis using the neighbor-joining method revealed that X and Y-linked RPS4 genes have evolved independently.

• Korean Journal of Veterinary Research
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• v.36 no.1
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• pp.161-167
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• 1996

Two cases of stomach mass and one case of tongue mass were observed in Japanese monkeys(Macaca fuscata) which were raised in Yong-in Farm Land. Histologically, two spontaneous tumors were found in the cardiac region of the stomach and were diagnosed as squamous cell carcinoma. These tumors had invaded the submucosa, muscular layer and serosa, but metastasis was not found in the other tissues including the lymph node. One spontaneous tongue mass was diagnosed as squamous cell carcinoma.

• Korean Journal of Veterinary Research
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• v.43 no.2
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• pp.301-305
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• 2003

To evaluate the effects of Zoletil (tiletamine- zolazepam) that have been widely used for the chemical restraint and anesthesia of primates, on physiologic alteration, blood gas analysis and anesthetic duration in the Japanese macaque(Macaca fuscata), this study was carried out. Zoletil was administered by intramuscular injection. Evaluation of temperature, heart rate, respiration rate and blood gas analysis were performed before administration and at 1, 10, 20, 30, 40, 50 and 60 min after administration, and induction and maintenance time was recorded. There was no significant difference in heart rate, $PCO_2$, $PO_2$ after Zoletil administration rut temperature, respiraticn rate, pH were significant difference compared with these of Mere administration. The induction time was $2.5{\pm}1.0min$ and maintenance time was $86{\pm}23.2min$. It was considered that Zoletil could be usefully used for the sedation and immobilization of Japanese macaque reared in zoological garden.

• Korean Journal of Veterinary Service
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• v.27 no.2
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• pp.165-169
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• 2004

In order to monitor the parasites, 83 fecal samples were taken from monkeys such as Cercopithecus mitis(6), Macaca fuscata(32), Saimiri sciurea(27), Macaca nigra(5), Papio hamadrysa(8), and Macaca mulatta(5) in Jeonbuk area. Isolation and Identification of the parasites from the feces were determined by the fecal examination using the floatation and microscopical examination, respectively. The detection rate was 21.6%, and mixed infection rate was single 18.0%(15 heads), double 2.4%(2 heads), and triple 1.2% (1 head). The isolates were identified as Strongyloides axei from 7 heads. Trichuris spp from 3 heads, Entamoeba histolytica 3 heads, Toxacaris leonina from 3 heads, and Eimeria spp from 2 heads.

• Proceedings of the Korean Society of Life Science Conference
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• 2002.09a
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• pp.77-78
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• 2002

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2005.11a
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• pp.61-61
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• 2005

• Parasites, Hosts and Diseases
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• v.50 no.3
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• pp.253-257
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• 2012

Natural habitat fragmentation and reducing habitat quality have resulted in an increased appearance of Japanese macaques, Macaca fuscata (Gray, 1870), in suburban areas in Japan. To investigate the risk of zoonotic infections, a coprological survey of helminth eggs passed by wild Japanese macaques was carried out in 2009 and 2010 in Shiga Prefecture, Japan. Microscopic examination found helminth eggs in high prevalence, and nucleotide sequencing of DNA extracted from the eggs identified Oesophagostomum cf. aculeatum and Trichuris trichiura. A fecal culture also detected infective larvae of Strongyloides fuelleborni. These zoonotic nematodes pose a potential health issue to local people in areas frequented by Japanese macaques.

• Korean Journal of Veterinary Service
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• v.33 no.1
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• pp.89-96
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• 2010

Hematological and serum biochemical values were assessed from 20 clinically healthy Japanese Macaques raised in Everland Zoological Gardens and compared to the International Species Information System (ISIS) reference range that is used internationally as standard for wildlife animals. Taking our standard on sexual maturation at age 4, tRBC values in Macaques under age 4 were significantly lower than those over age 4, but the Hb and PCV values were significantly higher. Compared to the ISIS standard, the tRBC values in Macaques under age 4 were significantly lower whereas the Hb and MCHC values were significantly higher. Moreover, in the samples of Macaques over age 4, the PCV and MCV values were significantly lower than the ISIS standard. On serum biochemistry values the creatinine and amylase values in the Macaques under age 4 were significantly lower than those over age 4. In comparison with the ISIS standard, the values of ALT, ALP, BUN, IP, $Ca^{2+}$ and $K^+$ in the Macaques under age 4 did have no significant difference. The values of TP, GGT, tBil, amylase, TG and UA were significantly higher than the ISIS standard, but the values of albumin, AST, glucose, creatinine, cholesterol, CPK, LDH, $Na^+$ and Clwere significantly lower. In contrast, the values of TP, albumin, ALT, ALP, creatinine, cholesterol, amylase, TG, IP and $Na^+$ in the Macaques over age 4 did have no significant difference, but the values of GGT, BUN, tBil, UA and $Ca^{2+}$ were significantly higher, while the values of AST, glucose, CPK, LDH, $K^+$ and $Cl^-$ were significantly lower. On the other hand, there was no significant difference in hematological and serum biochemical values between the groups of male and female.