Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
권호 표지
DOI QR코드

DOI QR Code

Solitary patent ductus arteriosus in a Japanese macaque (Macaca fuscata)

  • Young-Jin Jang (Department of Veterinary Medicine, College of Veterinary Medicine and Institute of Animal Transplantation, Jeonbuk National University) ;
  • Byung-Yong Park (Department of Veterinary Medicine, College of Veterinary Medicine and Institute of Animal Transplantation, Jeonbuk National University) ;
  • Hyun-Jin Tae (Department of Veterinary Medicine, College of Veterinary Medicine and Institute of Animal Transplantation, Jeonbuk National University) ;
  • Jeoungha Sim (Department of Nursing, College of Medical Science, Jeonju University) ;
  • Dongchoon Ahn (Department of Veterinary Medicine, College of Veterinary Medicine and Institute of Animal Transplantation, Jeonbuk National University)
  • Received : 2023.12.05
  • Accepted : 2023.12.14
  • Published : 2023.12.30
Download PDF
⟨ Previous Next ⟩

Abstract

Patent ductus arteriosus (PDA) in monkeys is very rare. A 9-year-old male Japanese macaque (Macaca fuscata) had an hourglass-shaped PDA with a large luminal diameter. Morphological analysis of the vessel cast and heart revealed cardiovascular pathological changes including pulmonary artery hypertension and right ventricular hypertrophy. However, left ventricle hypertrophy or left atrial enlargement were not observed. This macaque had showed no clinical signs of PDA during its lifetime. We present the first documented case of solitary PDA in a male macaque.

Keywords

Acknowledgement

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Ministry of Science and ICT (MSIT), Government of the Republic of Korea (Grant No. NRF-2019R1I1A3A01064272). We extend our sincere gratitude to the veterinarian who provided valuable information about the subject.

References

  1. Broaddus K, Tilson M. 2010. Patent ductus arteriosus in dogs. Compend Contin Educ Vet 32: E3.
  2. Freigang B, Knobil E. 1967. Patent ductus arteriosus with pulmonary hypertension and arteritis in a rhesus monkey. Yale J Biol Med 40: 239-242.
  3. Jerome CP. 1987. Congenital malformations and twinning in a breeding colony of old world monkeys. Lab Anim Sci 37: 624-630.
  4. Kammerlander AA, Aschauer S, Zotter-Tufaro C, Duca F, Knechtelsdorfer K, Wiesinger M, Schwaiger ML, Dalos D, Schneider M, Marzluf BA, Bonderman D, Mascherbauer J. 2017. Diameter of the pulmonary artery in relation to the ascending aorta: association with cardiovascular outcome. Radiology 284: 685-693. https://doi.org/10.1148/radiol.2017161849
  5. Koie H, Abe Y, Sato T, Yamaoka A, Taira M, Nigi H. 2007. Tetralogy of Fallot in a Japanese macaque (Macaca fuscata). J Am Assoc Lab Anim Sci 46: 66-67.
  6. Krichenko A, Benson LN, Burrows P, Moes CAF, McLaughlin P, Freedom RM. 1989. Angiographic classification of the isolated, persistently patent ductus arteriosus and implications for percutaneous catheter occlusion. Am J Cardiol 63: 877-880. https://doi.org/10.1016/0002-9149(89)90064-7
  7. McNamara PJ, Sehgal A. 2007. Towards rational management of the patent ductus arteriosus: the need for disease staging. Arch Dis Child Fetal Neonatal Ed 92: F424-F427. https://doi.org/10.1136/adc.2007.118117
  8. Miller MW, Gordon SG, Saunders AB, Arsenault WG, Meurs KM, Lehmkuhl LB, Bonagura JD, Fox PR. 2006. Angiographic classification of patent ductus arteriosus morphology in the dog. J Vet Cardiol 8: 109-114. https://doi.org/10.1016/j.jvc.2006.07.001
  9. Peterson PE, Short JJ, Tarara R, Valverde C, Rothgarn E, Hendrickx AG. 1997. Frequency of spontaneous congenital defects in rhesus and cynomolgus macaques. J Med Primatol 26: 267-275. https://doi.org/10.1111/j.1600-0684.1997.tb00222.x
  10. Reader JR, Canfield DR, Lane JF, Kanthaswamy S, Ardeshir A, Allen AM, Tarara RP. 2016. Left ventricular hypertrophy in rhesus macaques (Macaca mulatta) at the California National Primate Research Center (1992-2014). Comp Med 66: 162-169.
  11. Rishniw M, Caivano D, Dickson D, Vatne L, Harris J, Matos JN. 2019. Two-dimensional echocardiographic left-atrial-to-aortic ratio in healthy adult dogs: a reexamination of reference intervals. J Vet Cardiol 26: 29-38. https://doi.org/10.1016/j.jvc.2019.11.001
  12. Robinson WF, Robinson NA. 2016. Cardiovascular system. pp.17-19. In: Maxie MG(ed.). Pathology of domestic animals: Volume 3. 6th ed. Elsvier. St. Louis, Missouri.