• 대한물리치료과학회지
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• 제16권1호
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• pp.21-29
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• 2009

Background: The purpose of this study was to find out the effects of the hand movement exercise program on the cognitive function of the older with dementia. Methods: A total of twenty-four subjects were divided into two research groups and one control group, respectively. Each exercise was conducted in twelve weeks: three times a week, twice a day for fifteen minutes. Enhancement of cognitive function in each exercise program was evaluated four times using MMSE-KC, the Korean version of the Mini-Mental State. Results: As for enhancement of cognitive function, the hand movement exercise program represented an increase of $1.63{\pm}.92$ over those before study, showing significant differences (p<.05); the large muscle exercise program, $.75{\pm}.89$; and the activities of daily living program, $.00{\pm}2.14$, showing no significant differences. Conclusion: Hand Movement Exercise Program can be inferred from the results that consistent exercise program is more effective than any other ways for enhancement of cognitive function of the older with dementia.

• International Journal of Contents
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• 제6권1호
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• pp.41-46
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• 2010

The aim of this study was to investigate the effect of different shoe-heel heights on the surface electromyographic (EMG) activity of vastus medialis (VM) and vastus lateralis (VL) during treadmill walking in female patients with patellofemoral pain (PFP). Nineteen women with PFP participated in this research. EMG signals were recorded from the VM and VL of both sides and were compared during the treadmill walking. The subjects walked on a treadmill wearing shoes of three different heel heights: 1 cm, 3 cm and 7 cm. Each subject walked on a treadmill for five minutes at a speed of 2 km/hour with three minutes resting intervals between consecutive trials. The data were analyzed by one-way repeated-measures analysis of variance. The results of the present study indicate that EMG data of the VM and VL of female patients with PFP did improve with an increase in the height of the shoe heel, which were statistically significant. Additionally, the EMG activity of VM increased more dramatically than that of VL associated with the task of walking with high-heeled shoes on the treadmill. This study suggests that the type of high-heeled shoes is related to the VM and VL muscle activation patterns contributing to knee joint pathologies in female patients with PFP.

• The Journal of Korean Physical Therapy
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• 제27권4호
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• pp.270-274
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• 2015

Purpose: The purpose of this study was to examine the electromyographic (EMG) activity of the abdominal muscles and to compare the activity ratios of the bilateral rectus abdominis (RA) to oblique abdominal muscles during shoulder abduction in opposite directions with single leg raising (SLR) performed in the supine position on a foam roller. Methods: Fifteen healthy subjects were recruited to the study. Each subject lay on the foam roller and performed left single leg raising with right or left shoulder $90^{\circ}$ abduction (Abd); performed in a random order. Surface EMG recordings of selected abdominal muscles (i.e., the RA, external oblique abdominis [EO], internal oblique abdominis [IO], and transverse abdominis [TrA]) were normalized to maximum voluntary isometric contraction. EO/RA and IO and TrA/RA ratios were determined with surface EMG. Data were analyzed by Independent t-test. The statistical significance level was p<0.05. Results: The results were as follows: (1) the right RA, left EO, and right IO and TrA muscle activities increased significantly at the left SLR with left Abd compared to the left SLR with right Abd (p<0.05); and (2) the ratio of right EO/RA activity increased significantly at the left SLR with right Abd compared to left Abd (p<0.05). Conclusion: These findings suggest that left SLR with left Abd on a foam roller is an appropriate exercise for activation of specific oblique abdominal muscles.

• Food Science and Biotechnology
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• 제18권1호
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• pp.172-178
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• 2009

Fermented ginseng (FG) is an ethanol extract of ginseng radix processed with $\beta$-galactosidase. It was hypothesized that FG may exert anti-hyperlipidemic and anti-diabetic activities through modulating AMP-activated protein kinase (AMPK) in HepG2 human hepatoma cells. In this study, we showed that AMPK phosphorylation was stimulated by FG. These effects were abolished by pretreatment with an AMPK inhibitor, compound C. In addition, FG regulated the expression of genes associated with lipogenesis and lipolysis, thus causing suppression of hepatic triglyceride accumulation. In vivo study using db/db mice, FG reduced fasting plasma glucose, HbAlc, and insulin resistance index, when compared to diabetic control. FG also increased the phospho-AMPK and glucose transporter 4 (GLUT4) expressions in liver and skeletal muscle, respectively. In liver, expressions of lipogenic gene were decreased whereas expressions of lipolytic genes were induced, when compared to diabetic control. Taken together, we may suggest that FG ameliorates hyperglycemia and hyperlipidemia through activation of AMPK and could be developed as a health functional food or therapeutic agent for type 2 diabetic patients.

• 한국축산식품학회:학술대회논문집
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• 한국축산식품학회 2004년도 정기총회 및 제33차 춘계 학술대회
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• pp.198-201
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• 2004

To investigate hydrostatic pressure (HP) effect on myofibrillar protein (Mf) extracted from bovine Semitendinosus muscle, Ca- and Mg-ATPase activities to evaluate denaturation of myosin and actin, and soluble protein contents were observed. In Mf treated with 100 MPa for 5 min was not observed denaturation of myosin and actin. In Mf treated with 200 MPa for 5 min, denaturation of myosin and actin were observed but inactivation rate was low (0.0136 $min^{-1}$). Inactivation rate of myosin and actin was dramatically increased above 300 MPa treatment. However denaturation of myosin and actin was not that critical with duration time. By increasing pressure size, the amount of myosin and actin in soluble protein eluted in 20 mM potassium phosphate buffer (pH 7.0) containing 0.6 M NaCl were decreased. SDS-PAGE of soluble protein released from Mf suspension in 0.1 M NaCl buffer (pH 7.0) showed that low molecular weight proteins (15${\sim}$36 KDa) were released by HP treatment above 200 MPa. From the results, denaturation of myosin and actin, and release of light molecule proteins of Mf were observed by HP treatment over 200 MPa.

• 대한한방소아과학회지
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• 제29권2호
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• pp.16-25
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• 2015

Objectives The purpose of this study is to investigate the relationship between physical activity and growth indices. Methods 5963 of 12 years old adolescents were participated in the 10th Korea Youth Risk Behavior Web-Based Survey (KYRBWS-V) project in 2014. These data was analyzed to show the relationship between physical activity and height, BMI. Results According to the Physical Activity guidelines, the mean height was higher in the each male and female group with 'moderate physical activity for at least 60 min ${\geq}7$ days/week', 'vigorous physical activity ${\geq}3$ days/week', and 'muscle-strengthening activity ${\geq}3$ days/week' compare to the group who did not. The mean BMI was lower in the male group of 'sitting for watching TV or computer, etc on a weekday < 3 hr/day' compare to group who did not. Conclusions These results showed that physical activity in adolescence is correlated to growth. Therefore, this research can be one of the reference data to show the proper physical activity is important in the growth.

• 한국수산과학회지
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• 제40권4호
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• pp.193-200
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• 2007

Ion-exchange chromatography and ultra-filtration permeation were used to extract carnosine from the eel Anguilla japonica. In an investigation of its antioxidant properties, the eel carnosine prevented lipid peroxidation in linoleic acid systems, scavenged free radicals, and exhibited superoxide dismutase-like activity. These activities increased as the carnosine concentration increased. The nitrite scavenging effects (NSEs) of commercial carnosine and the eel carnosine were measured at various acidic pHs (1.2, 3.0, and 4.2). For both types of carnosine, the maximum NSE was observed at pH 1.2. At this pH, the NSE of the eel carnosine was 65.3%. Both types of carnosine were effective at maintaining reasonably good color of ground beef patties over 5 days of storage at $4^{\circ}C$ and inhibited metmyoglobin formation as well as lipid peroxidation. These data suggest that the eel carnosine might be useful as a "natural" antioxidant in commercial production and storage of muscle foodstuffs.

• 대한정형도수물리치료학회지
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• 제17권2호
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• pp.33-39
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• 2011

Background: The purpose of this study was to verify the most effective spinal stabilization exercise program by comparing the activities of muscles contributing to spinal stabilization during 2 types of exercises using 3-D NEWTON and a Gym-ball. Methods: We divided sixteen healthy students to two groups in D city were recruited and each subjects performed two type of exercise. Exercise 1 was performed 3-D NEWTON spinal stabilization training during 4 weeks (n=8). Exercise 2 was performed special training program that use a Gym-ball during 4 weeks (n=8). Results: The group of 3-D NEWTON applying lumbar stabilization kinetic program was increased 18.8s after training. Conclusions: It was revealed the statically significant difference between 3-D NEWTON and Gym-ball lumbar stabilization exercise groups. Therefore it has been turned out that 3-D NEWTON and Gym-ball lumbar stabilization exercise has an effect on the abdominis and trunk muscle strengthening and balance.

• KSBB Journal
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• 제28권1호
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• pp.36-41
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• 2013

Carotenoids are fat-soluble red-orange colored pigments found in plants and seafood-derived products, including algae, seaweeds, and fish muscle. In this study, we have demonstrated the molecular mechanism underlying the antioxidants and anti-inflammatory properties of ascidian tunic carotenoids using mouse macrophage cell line (RAW 264.7). Cell viability was not affected by treatment of carotenoids < 10 ${\mu}g/mL$. This treatment also showed negative inhibition on lipopolysaccharide (LPS)-stimulated nitric oxide (NO) and cyclooxygenase-2 (COX-2). The DPPH radical scavenging activity of carotenoids was 47.2% at 100 mg/mL. It also has a potential reducing power (1.025) comparable with ascorbic acid (1.584). The ascidian tunic carotenoids would make a candidate for the commercially interesting biologically active cosmetic pigments.

• 대한인간공학회지
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• 제28권4호
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• pp.17-23
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• 2009

The purpose of this study was to assess activation and contribution of muscles of the elderly according to increased loading during the arm flexion extension resistance exercise. Surface electromyographic signals were acquired from biceps brachii, triceps brachii, deltoid posterior, pectoralis major and latissimmus dorsi to determine the difference of the activation of specific muscles between the elderly and young. Five elderly and five young males with no musculoskeletal disease volunteered for the study. Electromyographic activities in the muscles were measured during resistance exercise and normalized to the maximum EMG activity recorded in the maximal voluntary static contraction (MVC). Against the increased loading during arm flexion/extension resistance exercises, the young uses muscles evenly but the elderly uses one specific muscle frequently. Contribution of triceps brachii during extension and deltoid posterior during flexion was principal in the elderly.