• Title/Summary/Keyword: MTC

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Loop-mediated isothermal amplification assay for differentiation of Mycobacterium bovis and M. tuberculosis (Mycobacterium bovis와 M. tuberculosis 감별을 위한 등온증폭법)

  • Koh, Ba-Ra-Da;Kim, Jae-Myung;Sung, Chang-Min;Ji, Tae-Kyung;Na, Ho-Myung;Park, Seong-Do;Kim, Yong-Hwan;Kim, Eun-Sun
    • Korean Journal of Veterinary Service
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    • v.36 no.2
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    • pp.79-86
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    • 2013
  • Mycobacterium (M.) bovis, a member of the M. tuberculosis complex (MTC), is a re-emerging, zoonotic agent of bovine tuberculosis whose prevalence probably depends on variations in direct exposure to cattle and ingestion of raw milk. Accurate species differentiation of M. bovis and M. tuberculosis is needed to distinguish between human and zoonotic tuberculosis. This study successfully developed a loop-mediated isothermal amplification (LAMP) assay for rapid detection and differentiation of M. bovis and M. tuberculosis, however showed negative reactions in eight non-tuberculous mycobacteria (NTM) samples and ten other bacterial species. Sensitivity of this assay for detection of genomic M. bovis DNA was 10 $fg/{\mu}l$. And this assay successfully detected M. bovis in bovine clinical specimens. In conclusion, the LAMP assay is a simple and powerful tool for rapid detection of M. bovis in both pure bacterial culture and in clinical samples.

Growth Stages of Maize (Zea mays, L.) (옥수수의 형태적 변화와 생장 발육 단계)

  • 박병훈;양종성;강정훈
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.26 no.2
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    • pp.185-191
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    • 1981
  • The purpose of this paper is to define and describe a series of growth stages for maize. cv. MTC-l (early) and Suweon No. 19 (late) that are easily identifiable by both professional agronomists and farmers. Plants were grown at a density of 60cm row with plant spacing of 15cm at six different seeding times in 1980. Leaf development indices with ten grades (LDI) were identified and defined in accordance with the development of a leaf blade. Leaf appearance rate (LAR) was ca. 3 days and it was not influenced by the variety or seeding time. The elongation of the first internode above the ground level began in a month after emergence and it corresponded to the 8th or 9th leaf stage. Internodes elongated in regular sequence of node position. The morphological change of silks related closely with the development of kernel. The duration of generative development was not influenced by varieties and seeding time but that of vegetative growth was influenced. A new scheme for the maize which was made by the developed leaves, visible nodes above ground level, morphological change of silks and development of kernel was proposed.

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Effective Distributed Supercomputing Resource Management for Large Scale Scientific Applications (대규모 과학응용을 위한 효율적인 분산 슈퍼컴퓨팅 자원관리 기술 연구)

  • Rho, Seungwoo;Kim, Jik-Soo;Kim, Sangwan;Kim, Seoyoung;Hwang, Soonwook
    • Journal of KIISE
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    • v.42 no.5
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    • pp.573-579
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    • 2015
  • Nationwide supercomputing infrastructures in Korea consist of geographically distributed supercomputing clusters. We developed High-Throughput Computing as a Service(HTCaaS) based on these distributed national supecomputing clusters to facilitate the ease at which scientists can explore large-scale and complex scientific problems. In this paper, we present our mechanism for dynamically managing computing resources and show its effectiveness through a case study of a real scientific application called drug repositioning. Specifically, we show that the resource utilization, accuracy, reliability, and usability can be improved by applying our resource management mechanism. The mechanism is based on the concepts of waiting time and success rate in order to identify valid computing resources. The results show a reduction in the total job completion time and improvement of the overall system throughput.

Physical Properties of Rigid Polyurethane Foams Prepared by Co-Blowing Agents (Co-blowing agent에 따른 경질 폴리우레탄 폼의 물성 변화 연구)

  • Kim Sang Bum;Koh Sung Ho
    • Journal of the Korean Institute of Gas
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    • v.8 no.2 s.23
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    • pp.1-7
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    • 2004
  • The physical properties of rigid polyurethane foam(PUF) synthesized using various types of blowing agents such as water, HFC-365mfc, HFC-245fa, HCFC-l4lb, CFC-11 and n-pentane were studied. The blending effect of blowing agents were also studied. The thermal conductivity, reaction rate, and cell morphology of the PUF with various blending ratio of blowing agents were investigated. The PUF blown by water shows the highest compressive strength among other single blowing agents. The thermal conductivity of PUFs blown by HFC-245fa and HFC-365mfc are close to that of PUFs blown by CFC-11. When HFC-365mfc was mixed with HFC-245fa(30mo1e$\%$) as coblowing agent, the mechanical property shows the highest value among other coblowing agents. It is that the thermal conductivity of PUFs depends on cell size of PUFs as well as thermal conductivity of blowing agent in gaseous form.

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Nonlinear numerical modelling for the effects of surface explosions on buried reinforced concrete structures

  • Nagy, N.;Mohamed, M.;Boot, J.C.
    • Geomechanics and Engineering
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    • v.2 no.1
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    • pp.1-18
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    • 2010
  • The analysis of structure response and design of buried structures subjected to dynamic destructive loads have been receiving increasing interest due to recent severe damage caused by strong earthquakes and terrorist attacks. For a comprehensive design of buried structures subjected to blast loads to be conducted, the whole system behaviour including simulation of the explosion, propagation of shock waves through the soil medium, the interaction of the soil with the buried structure and the structure response needs to be simulated in a single model. Such a model will enable more realistic simulation of the fundamental physical behaviour. This paper presents a complete model simulating the whole system using the finite element package ABAQUS/Explicit. The Arbitrary Lagrange Euler Coupling formulation is used to model the explosive charge and the soil region near the explosion to eliminate the distortion of the mesh under high deformation, while the conventional finite element method is used to model the rest of the system. The elasto-plastic Drucker-Prager Cap model is used to model the soil behaviour. The explosion process is simulated using the Jones-Wilkens-Lee equation of state. The Concrete Damage Plasticity model is used to simulate the behaviour of concrete with the reinforcement considered as an elasto-plastic material. The contact interface between soil and structure is simulated using the general Mohr-Coulomb friction concept, which allows for sliding, separation and rebound between the buried structure surface and the surrounding soil. The behaviour of the whole system is evaluated using a numerical example which shows that the proposed model is capable of producing a realistic simulation of the physical system behaviour in a smooth numerical process.

Clinical effectiveness of different types of bone-anchored maxillary protraction devices for skeletal Class III malocclusion: Systematic review and network meta-analysis

  • Wang, Jiangwei;Yang, Yingying;Wang, Yingxue;Zhang, Lu;Ji, Wei;Hong, Zheng;Zhang, Linkun
    • The korean journal of orthodontics
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    • v.52 no.5
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    • pp.313-323
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    • 2022
  • Objective: This study aimed to estimate the clinical effects of different types of bone-anchored maxillary protraction devices by using a network meta-analysis. Methods: We searched seven databases for randomized and controlled clinical trials that compared bone-anchored maxillary protraction with tooth-anchored maxillary protraction interventions or untreated groups up to May 2021. After literature selection, data extraction, and quality assessment, we calculated the mean differences, 95% confidence intervals, and surface under the cumulative ranking scores of eleven indicators. Statistical analysis was performed using R statistical software with the GeMTC package based on the Bayesian framework. Results: Six interventions and 667 patients were involved in 18 studies. In comparison with the tooth-anchored groups, the bone-anchored groups showed significantly more increases in Sella-Nasion-Subspinale (°), Subspinale-Nasion-Supramentale(°) and significantly fewer increases in mandibular plane angle and the labial proclination angle of upper incisors. In comparison with the control group, Sella-Nasion-Supramentale(°) decreased without any statistical significance in all treated groups. IMPA (angle of lower incisors and mandibular plane) decreased in groups with facemasks and increased in other groups. Conclusions: Bone-anchored maxillary protraction can promote greater maxillary forward movement and correct the Class III intermaxillary relationship better, in addition to showing less clockwise rotation of mandible and labial proclination of upper incisors. However, strengthening anchorage could not inhibit mandibular growth better and the lingual inclination of lower incisors caused by the treatment is related to the use of a facemask.

Study on the 3GPP International Standard for M2M Communication Networks (M2M네트워크통신을 위한 3GPP 국제표준화 동향연구)

  • Hwang, Jin-ok;Lee, Sang-Gi
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.40 no.6
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    • pp.1040-1047
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    • 2015
  • This study is investigated for M2M Communication Network Standard based on 3GPP. The environment of M2M communication, we can predict the new mobile service that gathering, handling, controlling, transferring of the data for Intelligence, so that we can consider new direction for a lot of subject of study development issue. This study is shown three types of M2M network structure and four types of use cases on 3GPP International Standard. In Addition, we can introduce the future M2M communication network model, it can be propagate the industry and academic cooperation with 3GPP standards. The suggestion develops multiple applications and multiple devices for industry and academic. With the deployment of network provider, this environment support our current communication market that the standard devices of M2M network and service requirement. We are suggest this study for grasp the initial market with the intellectual property right (IPR) based on International Standards. In the future, we wish the success that grap the initial market or initial academic study with helpful issue.

Group-based Random Access Using Variable Preamble in NB-IoT System (NB-IoT 시스템에서 가변 프리앰블을 이용한 그룹 랜덤 액세스)

  • Kim, Nam-Sun
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.13 no.5
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    • pp.370-376
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    • 2020
  • In this study, we consider a group-based random access method for group connection and delivery by grouping devices when H2H devices and large-scale M2M devices coexist in a cell in NB-IoT environment. H2H devices perform individual random access, but M2M devices are grouped according to a NPRACH transmission period, and a leader of each group performs random access. The preamble is allocated using the variable preamble allocation algorithm of the Disjoint Allocation(DA) method. The proposed preamble allocation algorithm is an algorithm that preferentially allocates preambles that maximizes throughput of H2H to H2H devices and allocates the rest to M2M devices. The access distribution of H2H and M2M devices was set as Poisson distribution and Beta distribution, respectively, and throughput, collision probability and resource utilization were analyzed. As the random access transmission slot is repeated, the proposed preamble allocation algorithm decreases the collision probability from 0.93 to 0.83 and 0.79 when the number M2M device groups are 150. In addition, it was found that the amount of increase decreased to 33.7[%], 44.9[%], and 48.6[%] of resource used.