• Geophysics and Geophysical Exploration
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• v.27 no.1
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• pp.37-50
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• 2024

The magnetotelluric (MT) survey can be affected by external environmental factors. In particular, when acquiring MT data in islands, it is essential to consider the combined effect of topography and sea to understand the results and make accurate interpretations. To analyze the MT response (apparent resistivity, phase) with consideration of the effect of topography and sea, a small cone-shaped island model surrounded by deep sea was created. Two-dimensional (2-D) and three-dimensional (3-D) forward modeling were performed on the terrain model considering topography and the island model considering both topography and sea. The 2-D MT response did not reflect the topographic and sea effect of the direction orthogonal to the 2-D profile. The 3-D MT response included topographic and sea effects in all directions. The XY and YX components of the apparent resistivity were separated on undulating topography, such as a hill. A conductor at 1 km below sea level could be distinguished from topographic and sea effects in the MT response, and low resistivity anomaly was attenuated at greater depths. This study will facilitate understanding of field data measured on small islands.

• The Korean Journal of Ecology
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• v.10 no.3
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• pp.109-118
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• 1987

The production and decomposition rates of litters were studied in three mountains, Mt. Halla, Mt. So-back and Mt. Tae-back. The amounts of N, P, K, Ca and Na in the soils were measured and the relationships between the mineral nutrients and decay rates were reserched, The annual litter production was the most as $1, 077.3g/m^2$ and the least as $248.0g/m^2$ in a stand of Quercus acutissima at 820m of the Mt. So-back and at 1, 350m of the Mt. So-back among the study sites, respectively. The decay rates of litter was the highest as k=0.448 and the lowest as k=0.082 in a stand of Q. acutissima at 820m of the Mt. So-back and at 1, 450m of the Mt. Tae-back at 1, 450m of the Mt. Tae-back among the study sites. The higher altitude was, the slower the decay rates were. The annual contents of mineral nutrient and their amounts inputted into the forest soil were proportional to the decay rate of organic metters.

• Journal of The Korean Society of Grassland and Forage Science
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• v.22 no.1
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• pp.23-30
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• 2002

Eveuadies 71' kenaf (Hibiscus cannabinus L.) was grown at five plant densities (1, 2, 3, 4, and 5 plants per hill; 16,000, 32,000, 48,000, 64,000 and 80,000 plants/10a) from April 13 to October 8, 2001 in Jeju island to determine influence of plant number per hill on agronomic characteristics, forage yield and quality. As plant density increased from 1 to 5 plants per hill, the plant height averaged across two harvests increased 176 to 185 cm. Compared with the plant density of two plants per hill, the plant height decreased at higher plant densities (183, 180, and 166 cm for 3, 4 and 5 plants per hill). The highest yield of fresh forage (114.6 MT/ha), dry matter (17.3 MT/ha), crude protein (2.33 MT/ha), and total digestible nutrients (TDN) (9.21 MT/ha) was obtained at 2 plants per hill. As plant density increased from 1 to 5 plants per hill, crude protein, ether extract, nitrogen free extract, and TDN contents increased from 13.1 to 15.4%, 3.0 to 3.7%, 20.1 to 23.2% and 41.1 to 45.4%, respectively, while crude fiber and crude ash contents decreased from 41.2 to 34.9% and 9.4 to 8.2%, respectively.

• Proceedings of the Korean Geotechical Society Conference
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• 2010.09a
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• pp.1122-1129
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• 2010

Various soil tests were performed in the laboratory after soil samples were obtained from natural terrains distributed on the granitic rocks where are located in Mt. Bukhan, Mt. Surak and Mt. Gwanak around Seoul. Through the comparison of soil properties in each mountain, the difference of soil properties in a similar geological condition was investigated. According to the result of soil test, the soils were generally classified into calyey and silty sands with a well grade. Soil densities are ranged from $2.62kg/cm^3$ to $2.67kg/cm^3$, and water contents of soils are ranged from 3.77% to 31.12%. These values are not sorted locally. The wet unit weights of soils are ranged from $1.092kg/cm^3$ to $1.814kg/cm^3$. It has a big difference between the average values because that of Mt. Bukhan is $1.604kg/cm^3$ and those of Mt. Surak and Mt. Gwanak are $1.500kg/cm^3$ and $1.331kg/cm^3$, respectively. The internal friction angles are ranged from $31^{\circ}$ to $39^{\circ}$ and the cohesions are ranged from 1.57kPa to 8.63kPa. The shear strengths are too high and similar in all regions. The coefficients of permeability are ranged from $3.07{\times}10^{-3}cm/sec$ to $4.61{\times}10^{-2}cm/sec$. So, these soils are evaluated as a middle to high permeable ground. On average, the value of Mt. Bukhan is $1.47{\times}10^{-2}cm/sec$ and the values of Mt. Surak and Mt. Kwanak are $1.29{\times}10^{-2}cm/sec$ and $1.66{\times}10^{-2}cm/sec$, respectively.

• Journal of Pharmaceutical Investigation
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• v.23 no.3
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• pp.9-18
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• 1993

Sugar spheres loaded with melatonin (MT) were coated with $Aquacoat^{\circledR}$ to control the release rate of MT over 8 hours. A zero-order release pattern over 8 hours was obtained with 20% coating on 8-10 mesh beads in USP basket dissolution studies. MT in 20% coated beads was quite stable at room temperature with less than 5% MT degraded during 6 months' storage. Dissolution profiles were also unchanged after 6 months. An oral preparation containing MT-loaded uncoated beads for immediate release and 20% coated beads with $Aquacoat^{\circledR}$ for controlled release over 8 hours was evaluated in six human subjects. When total 0.5 mg MT as low dose (immediate release portion of MT, 0.1 mg) was administered to four subjects, average peak plasma MT concentration was reached at about 600 pg/ml and maintained at about 10 pg/ml over 8 hours. Plasma MT concentration-time profiles were similar in shape to computer-simulated profiles. However, maximal plasma MT concentrations were three times greater compared to computer simulated curve. These results suggest that MT dose, ratio of immediate and controlled release MT, and pharmacokinetic parameters selected are adjusted to mimic endogenous MT concentration-time curve. In another study, 0.2 mg MT having 10% of immediate release portion and 80% controlled release portion produced plasma MT concentration-time curve which is more similar to endogenous profiles. A low bioavailability (<20%) may result from extensive first pass metabolism and remaining amounts of MT from controlled beads. A good correlation between plasma MT concentration and urinary excretion rate of 6-sulphatoxymelatonin (6-STMT), a major metabolite of MT was observed. As plasma MT concentration increased, urinary excretion rate of 6-STMT increased concomitantly. The linear relation between plasma MT and urinary excretion rate of 6-STMT was statistically significant. This result suggests that urinary 6-STMT may be used as an index of circadian rhythms of MT in humans.

• Journal of the Korean Society of Marine Environment & Safety
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• v.12 no.1 s.24
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• pp.15-22
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• 2006

Marine Technology is the last hope of mankind for resolving predestined issues of food, resources, and environmental problems. facing and realizing this great challenge, domestic industrial, academic and research institutional experts participated in formulating the Marine Technology development plan, and the national science and technology committee chaired by the president passed this important plan thus setting the foundation for activating and promoting MT development. A project to develop Marine Technology Road Map(MTRM) has been carried out since June of 2005 for effective execution of the plan 1his paper reviewed current issues of MT and contents of MTRM, and proposed alternative measures for MT activation and promotion such as the establishment of special institutes for managing MT research and development and the fund raising for MT budget.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.27 no.4
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• pp.314-320
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• 2001

Matrix metalloproteinases have long been viewed as ideal candidates for proteinases that enables tumor cells to permeated basement membrane defenses and invade surrounding tissue. There is growing evidence that the MMPs have an expanded role, as they are important for the creation and maintenance of a microenvironment that facilitates growth and angiogenesis of tumors at primary and metastatic sites. MT-MMPs are not secreted but instead remaining attached to cell surfaces. Although not all of the MT-MMPs are fully characterized, MT-MMPs have important role in localizing and activating secreted MMPs. The MMP genes are transcriptionally responsive to a wide variety of oncogene, growth factors, cytokine, and hormones. Currently, a number of MMP inhibitors are being developed and some have reached clinical trials as anti-metastatic or anti-cancer therapies. MT1-MMP is involved in the activation of proMMP-2. MT1-MMP is significant not only as a tumor marker but as a new target for chemotherapy against cancer. The purpose of this study was to evaluate the effects of protein kinase C inhibitor(genistein) on the proliferation of HT1080 and expression of MT1-MMP mRNA. Human fibrosarcoma cell line HT1080 was cultured and divided 2 groups. The experimental group was treated with $100{\mu}M$ genistein and incubated 12h, 24h for $[3^H]-thymidine$ uptake assay and northern hybridization individually. And the control group was treated with same amount of PBS for the above procedures. $[3^H]-thymidine$ incorporation was measured with ${\beta}$ ray detector. And RT-PCR and northern blotting for MT1-MMP mRNA was performed. The results were as follows 1. $[3^H]-thymidine$ uptake was reduced in experimental group with statistical significance. 2. MT1-MMP mRNA expression was significantly reduced in experimental group. These results showed that protein kinase C inhibitor (genistein) inhibited proliferation of HT1080 and almost completely blocked transcription of MT1-MMP mRNA. So, it is possible to use the protein kinase inhibitor (genistein) as anti-metastatic and anti-proliferative agent.

• Journal of Korean Society of Forest Science
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• v.95 no.5
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• pp.562-568
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• 2006

This study was conducted to examine the energy content and photosynthetic efficiency of Quercus mongolica stands in Korea. Study sites were located in Mt. Joongwang, Gangwon-do (1,000 m and 800 m above sea level), Mt. Baekwoon, Jeollanam-do (800 m a.s.l.), Mt. Halla, Jeju-do (1,000 m a.s.l.), Mt. Taehwa, Gyeonggi-do (350 m a.s.l.), and Mt. Wolak, Chungcheongbuk-do (300 m a.s.l.). Total energy content and annual energy accumulation in Q. mongolica stands were 2,916-6,435 GJ/ha and 284-441 GJ/ha, respectively. Lower latitude (N.L.) stands of Q. mongolica showed higher energy contents than higher latitude stands, but Quercus stands in Mt. Baekwoon had higher annual energy accumulation than those in Mt. Halla located at a lower latitude. During the growing season, the photosynthetic efficiency of 60 to 70-year-old Q. mongolica stands ranged from 1.19 to 1.34% while that of 35-year-old stands did from 1.87 to 1.95%. There were no significant differences in photosynthetic efficiency among the latitudes because solar radiation was higher in low latitudes.

• Journal of The Korean Society of Grassland and Forage Science
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• v.23 no.3
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• pp.143-150
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• 2003

This study was conducted to determine the response of main growth characters, yield and chemical composition of Jeju native soybean based on the difference between phosphate rates (0, 50, 100, 150, 200, 250kg/ha) from May 11 to September 10 in 2002 in Jeju island. Days to flowering was delayed from 92 days to 97 days as the increasing of phosphate rate. Also plant height grew longer from 109cm to 124cm. The number of branches and leaves, stem diameter, root length and weight of root grew powerful as phosphate rate increased from 0 to 250kg/ha. Fresh forage yield was 26.5MT/ha in the nonphosphate plot and then was 36.9MT/ha as phosphate rate increased to 250kg/ha. And the difference between 200kg/ha and 250kg/ha in phosphate rate was not significant. Dry matter, crude protein and TDN yield increased 6.0∼7.9MT/ha, 0.9∼1.4MT/ha and 3.4∼4.9MT/ha respectively, as the increasing of phosphate rate. Also crude protein, crude fat, NFE and TDN content increased 15.5∼18.3%, 2.2∼3.3%, 42.5∼43.5%, and 56.7∼61.9% respectively. In contrast with this, crude fiber and crude ash decreased 32.1∼28.1% and 7.7∼6.8% respectively. To reach the climax of forage yield was estimated optimum phosphate rate to be 200kg/ha.

• Journal of the Korean Wood Science and Technology
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• v.34 no.4
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• pp.54-65
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• 2006

This study was conducted to examine the biomass and energy content of 60- to 70-year-old Quercus mongolica stand facing northern and southern aspect in Mt. Baekwoon (800 m above sea level), Gwangyang, Jeollanam-do and in Mt. Halla (1,000 m above sea level), Jeju-do. The total biomass was 288.4 ton/ha in northern aspect and 241.9 ton/ha in southern aspect of Mt. Baekwoon while 368.4 ton/ha in northern aspect and 364.3 ton/ha in southern aspect of Mt. Halla. Annual net production was 20.7 ton/ha/yr in northern aspect and 17.7 ton/ha/yr in southern aspect of Mt. Baekwoon while 19.0 ton/ha/yr in northern aspect and 21.2 ton/ha/yr in southern aspect of Mt. Halla. Total biomass and annual net production of Mt. Halla were greater than those of Mt. Baekwoon. The net assimilation rate (NAR) was 5.05 in northern aspect and 4.09 in southern aspect of Mt. Baekwoon, while 4.60 in northern aspect and 3.66 in southern aspect of Mt. Halla, Total energy content was 5,666 GJ/ha in northern aspect and 4,793 GJ/ha in southern aspect of Mt. Baekwoon while 6,550 GJ/ha in northern aspect and 6,435 GJ/ha in southern aspect of Mt. Halla. Annual energy content was 365 GJ/ha/yr in northern aspect and 360 GJ/ha/yr in southern aspect of Mt. Baekwoon while 351 GJ/ha/yr in northern aspect and 347 GJ/ha/yr in southern aspect of Mt. Halla. Annual energy content of Mt. Baekwoon was greater than that of Mt. Halla.