• 대한치과교정학회지
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• 제53권4호
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• pp.219-231
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• 2023

Objective: This study aimed to clarify differences in the positions of cone-beam computed tomography (CBCT) landmarks according to different midsagittal planes (MSPs) in patients with skeletal Class III facial asymmetry. Methods: Pre-treatment CBCT data from 60 patients with skeletal Class III were used. The patients were classified into symmetric (menton deviations of < 2 mm) or asymmetric (menton deviations of > 4 mm) groups. Six MSPs were established based on previous studies, and three-dimensional analyses were performed for the planes in both the groups. The measurement outcomes were compared statistically. Results: A statistically significant interaction (p < 0.01) was observed between MSPs and facial asymmetry. No significant differences were observed among MSPs in the symmetric group. However, significant differences in linear measurements were identified among MSPs in the asymmetric group. Specifically, the upper facial MSP revealed both maxillary and mandibular transverse asymmetries. On the other hand, anterior nasal spine (ANS)-associated MSP could not identify maxillary asymmetry. Furthermore, the menton deviation was approximately 3 mm lower when estimated using the ANS-associated MSP than that using upper facial MSP. Conclusions: The choice of MSP can significantly affect treatment outcomes while diagnosing patients with asymmetry. Therefore, care should be taken when selecting MSP in clinical practice.

• Imaging Science in Dentistry
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• 제49권2호
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• pp.159-169
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• 2019

Purpose: Cone-beam computed tomography (CBCT) is widely used for 3-dimensional assessments of cranio-maxillo-facial relationships, especially in patients undergoing orthognathic surgery. We have introduced, for reference in CBCT cephalometry, an anatomical mid-sagittal plane (MSP) identified by the nasion, the midpoint between the posterior clinoid processes of the sella turcica, and the basion. The MSP is an updated version of the median plane previously used at our institution for 2D posterior-anterior cephalometry. This study was conducted to test the accuracy of the CBCT measures compared to those obtained using standard posterior-anterior cephalometry. Materials and Methods: Two operators measured the inter-zygomatic distance on 15 CBCT scans using the MSP as a reference plane, and the CBCT measurements were compared with measurements made on patients' posterior-anterior cephalograms. The statistical analysis evaluated the absolute and percentage differences between the 3D and 2D measurements. Results: As demonstrated by the absolute mean difference (roughly 1 mm) and the percentage difference (less than 3%), the MSP showed good accuracy on CBCT compared to the 2D plane, especially for measurements of the left side. However, the CBCT measurements showed a high standard deviation, indicating major variability and low precision. Conclusion: The anatomical MSP can be used as a reliable reference plane for transverse measurements in 3D cephalometry in cases of symmetrical or asymmetrical malocclusion. In patients who suffer from distortions of the skull base, the identification of landmarks might be difficult and the MSP could be unreliable. Becoming familiar with the relevant software could reduce errors and improve reliability.

• 대한수의학회지
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• 제51권2호
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• pp.107-115
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• 2011

Theileria (T.) buffeli (formerly T. sergenti/T. orientalis) is the major hemo-protozoan distributed in the Far East Asian countries such as Korea, China and Japan. It is responsible for the clinical symptoms of anorexia, ateliosis, anemia, fever and icterus. It also causes abortion and sudden death under severe cases, resulting in economic losses for many livestock farms. The objective of this study was to analyze the genetic diversity of the major surface protein (Msp) gene in T. buffeli in Holstein in Korea, and we characterized the association of the diversification of the Msp gene and its relationship with the pathogenicity of Theileria. For this, complete blood counts and Theileria PCR sequence analysis were performed from 57 Holstein in Jeju Island. A total of 26 PCR positive Holstein (16 anemic and 10 non-anemic) were then randomly selected based on 18s rRNA sequence typing of the Theileria Msp gene. The DNA sequence of the T. buffeli Msp gene in Holstein showed 99.0%, 99.2%, 99.9%, 99.5%, 98.7%, 98.4% and 98.4% homology with T. sergenti, Theileria spp., T. sergenti, Theileria spp., Theileria spp., Theileria spp. and Theileria spp., respectively. The result showed a genetic variation of 57.7% (type I), 3.8% (type II), 15.4% (type III), 7.7% (type IV), 13.5% (type V) and 1.9% (type VI). Type I is the most frequent type in both anemic and non-anemic Holstein while type II was found in only non-anemic Holstein. This results of our study help confirm the diversity of Msp gene types and demonstrate that the gene type distribution of Msp genes varies among Theileria-infected Holstein in Jeju Island.

• 한국임상수의학회지
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• 제15권1호
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• pp.140-145
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• 1998

The present study was carried out for the rapid and accurate detection of Anaplasma marginale in cattle using Polymerase Chain Reaction. One pair of primer, BAP-2 and AL34S, were designed to amplify a 409 Up fragment of the A marginale membrane surface protein encoding beta($msp{\beta}l$) gene with a hilly sensitive and specific PCR. A marginale isolated from naturally infected calf in Chonbuk area were used to obtain target genomic DNA for PCR. This study showed that a 409 bp of $msp{\beta}l$ gene fragment could be detected as little as 15 fg of purified A marginale genomic DNA. The amplified fragment with PCR was checked for the identification of $msp{\beta}l$ gene by enzyme restriction and sequencing. Also, the target DNA extracted directly from blood were used in the PCR reactions without prior purification to shorten the detection time. The PCR in the present study was considered convenient and rapid method for the detection of A marginale in whole blood of infected cattle.

• Parasites, Hosts and Diseases
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• 제53권4호
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• pp.413-419
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• 2015

The present study determined and compared the genetic diversity of Plasmodium falciparum strains infecting children living in 2 areas from Gabon with different malaria endemicity. Blood samples were collected from febrile children from 2008 to 2009 in 2 health centres from rural (Oyem) and urban (Owendo) areas. Genetic diversity was determined in P. falciparum isolates by analyzing the merozoite surface protein-1 (msp1) gene polymorphism using nested-PCR. Overall, 168 children with mild falciparum malaria were included. K1, Ro33, and Mad20 alleles were found in 110 (65.5%), 94 (55.9%), and 35 (20.8%) isolates, respectively, without difference according to the site (P>0.05). Allelic families' frequencies were comparable between children less than 5 years old from the 2 sites; while among the older children the proportions of Ro33 and Mad20 alleles were 1.7 to 2.0 fold higher at Oyem. Thirty-three different alleles were detected, 16 (48.5%) were common to both sites, and 10 out of the 17 specific alleles were found at Oyem. Furthermore, multiple infection carriers were frequent at Oyem (57.7% vs 42.2% at Owendo; P=0.04) where the complexity of infection was of 1.88 (${\pm}0.95$) higher compared to that found at Owendo ($1.55{\pm}0.75$). Extended genetic diversity of P. falciparum strains infecting Gabonese symptomatic children and high multiplicity of infections were observed in rural area. Alleles common to the 2 sites were frequent; the site-specific alleles predominated in the rural area. Such distribution of the alleles should be taken into accounts when designing MSP1 or MSP2 malaria vaccine.

• 해양환경안전학회지
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• 제15권3호
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• pp.237-242
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• 2009

최근 육상부존자원의 한계봉착과 신물질개발 및 국제 물류 이동의 증가 등으로 인하여 해양개발수요가 증가하고 있다. 해양에서의 개발행위는 해양생물과 그 서식지에 외부불경제를 유발한다. 이러한 보호와 개발간의 대립을 극복하고 지속가능한 해양이용을 추구하기 위해 고안된 제도가 해양공간계획이다. 본 논문은 해양공간 계획제도가 가지는 효과를 경제적, 생태적, 정책적 측면으로 구분하여 분석하였으며, 우리나라에서 해양공간계획제도의 도입이 필요한 이유를 설명하고 해양공간계획 제도의 성공을 위한 전제조건을 제시하였다.

• Journal of Advanced Marine Engineering and Technology
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• 제39권1호
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• pp.86-93
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• 2015

최근 선박의 안전항해를 위해 해사서비스 목록인 MSP에 대한 국제적인 논의가 활발하게 진행되고 있다. 성공적으로 MSP를 개발하기 위해서는 먼저 MSP의 구조와 데이터 표준화가 되어야 한다. 또한 육상-선박, 선박-선박 간 제공되는 IT서비스가 안전항해에 효과적인지 평가하고 데이터의 전달 및 표현방법에 대한 사전 적합성 검토가 필요하다. 따라서 본 논문에서 제안하는 시뮬레이션 시스템은 항해사 교육 목적으로 사용하는 선박 조종 시뮬레이터와 달리 일반 PC 환경에서 동작하여 MSP의 IT서비스를 개발하고 검증하는 것을 목적으로 설계하였다. 시스템은 시나리오 편집기 모듈과 항해환경 3차원 시각화 모듈, 항해기기 2차원 시각화 모듈로 구성되어 있다. 시나리오 편집기 모듈은 시뮬레이션 시나리오를 작성하고 시뮬레이션을 운용하는 기능을 제공한다. 항해환경 3차원 시각화 모듈은 작성된 시나리오에 따라 해상환경과 항해환경의 상호작용을 3차원으로 표현하는 기능을 제공한다. 항해기기 2차원 시각화 모듈은 선박의 주요 항해기기의 상호작용을 2차원으로 표현하는 기능을 제공한다. 개발된 시뮬레이션 시스템을 이용하여 다수 선박이 항구에 입 출항하는 항해환경을 구성하고 자선을 항구에 입항하는 시험을 행하여 국제해사기구에서 개발되어진 일부 MSP의 효용성을 평가하기 위한 시뮬레이션에 사용할 수 있다는 것을 확인하였다.

• 제어로봇시스템학회지
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• 제4권2호
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• pp.15-17
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• 1998

DSP(Digital Signal Processor)는 신호처리의 응용에 있어서 실시간 처리가 요구되는 경우 탁월한 성능을 나타낸다. 멀티미디어 서비스를 위해서는 전송되어 들어오는 데이터를 빠른 시간에 처리를 하여 원하는 서비스를 제공해야 한다. 따라서 사용자 측에서는 전송된 데이터의 실시간 처리를 위한 특별한 장치가 요구된다. 본 논문에서는 이러한 용도를 위해 DSP를 이용하여 MSP(Multimedia Signal Processor)를 설계한다.

• 지역사회간호학회지
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• 제30권2호
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• pp.161-173
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• 2019

Purpose: This study was conducted to develop and test a measurement of the suicidal protection(MSP) for high school students in Korea. Methods: Thirty-four preliminary items were initially developed based on literature review and focus group interviews. Those items were evaluated by experts for content validity with 31 items yielded. For testing validity and reliability of the measurement, data were collected from 330 high school students in Korea. Results: The item analysis selected 26 items. One item was deleted additionally through the primary exploratory factor analysis. The final exploratory factor analysis yielded 26 items in six factors such as fear of suicide, self-esteem, emotion regulation, support from others, support from family, and school life, explaining 66.6% of the total variance of the suicidal protection for high school students in Korea. Convergent validity and discriminant validity were supported by construct reliability, average variance extracted estimate, and standardized regression weight. MSP scores were positively associated with economic status, academic record and suicidal ideation. Also, criterion validity was supported through a significant correlation with the Reason for Living Inventory for Adolescent. The Cronbach's ${\alpha}$ reliability coefficient was .93 for the overall measurement and .72~.86 for the six factors. Conclusion: The results show that MSP may be valid and reliable for assessing suicidal protection of high school students.

• 대한의용생체공학회:의공학회지
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• 제22권5호
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• pp.439-448
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• 2001

이식형 양심실 보조 장치 (Biventricular Assist Device, BVAD)에서 판막이 닫힐 때 나는 소리의 특성과 판막의 물리적인 상태의 상관성을 고찰하였다. 본 연구에서 Bj rk Shiley Convexo Concave tilting disk 판막을 사용했으며, 모의 순환계와 양의 체내에서 동작하는 BVAD 에서 판막음을 측정하였다. 모의 순환계에서는 정상 판막. 기계적으로 손상된 판막. 모의 혈전이 형성된 판막의 3가지를 고려하였다. 양에 이식된 BVAD의 경우, 이식 후 1일부터 5일 동안 규칙적인 간격으로 판막음을 측정하였다. 측정된 신호의 스펙트럼 특성은 Multiple Signal Classification (MUSIC)을 이용하여 추정하였다. MUSIC의 최적 차수는 Bayesian Information Criterion (BIC)을 이용하여 계산하였다. 실험 결과, 판막의 기계적인 손상은 판막 폐쇄음의 주파수 스펙트럼 구조를 변화시키고 있으며, 혈전의 형성은 판막음 스펙트럼의 기본 구조는 유지하지만 피크 주파수와 에너지의 크기를 변화시키는 것으로 관찰되었다. 최대 에너지를 가지는 MSP (maximum spectral peak)는 정상 판막에서는 2 kHz에 위치하고 있으나 모의 혈전을 부탁한 판막에서는 3 kHz로 이동하였다. 손상된 판막은 7 kHz 부근에서 강한 피크 보이고 있다 실험 동물 내에서 판막에 혈전이 형성되어감에 따라 판막음은 저주파 성분 (〈 2kHz)이 상대적으로 크게 감소하였고, Ist 2nd. 3rd MSP 주파수는 약간씩 상승하였다. 또한 혈전이 형성되어 감에 따라 반복해서 측정된 판막음의 1st, 2nd. 3rd MSP 주파수의 변화 정도 및 BIC 차수는 감소하는 것으로 나타났다